Synthesis and Characterization of Biomedical Materials PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Synthesis and Characterization of Biomedical Materials PDF full book. Access full book title Synthesis and Characterization of Biomedical Materials by Leszek Adam Dobrza ́ Nski. Download full books in PDF and EPUB format.
Author: Leszek Adam Dobrza ́ Nski Publisher: Mdpi AG ISBN: 9783036525228 Category : Technology & Engineering Languages : en Pages : 544
Book Description
This book aims to summarize the latest achievements in the development and manufacturing of modern biomaterials used in modern medicine and dentistry, for example, in cases where, as a result of a traffic or sports accident, aging, resection of organs after oncological surgery, or dangerous inflammation, there is a need to replace lost organs, tissues, and parts of the human body. The essence of biomedical materials is their constant contact with living tissues, organisms, or microorganisms and, therefore, they should meet numerous requirements from various fields, including medicine, biology, chemistry, tissue engineering, and materials science. For this reason, biomaterials must be compatible with the organism, and biocompatibility issues must be addressed before using the product in a clinical setting. The production and synthesis of biomaterials require the use of various technologies and methods to obtain the appropriate material, which is then processed using advanced material processing technologies. Often, however, it is necessary to directly manufacture a specific product with individualized geometric features and properties tailored to the requirements of a particular patient. In such cases, additive manufacturing methods are increasingly used. In this sense, it can be considered that the Biomaterials 4.0 stage has been reached, and detailed information is included in the individual chapters of this book on the achievements in the development and manufacturing of modern biomaterials used in modern regenerative medicine, regenerative dentistry, and tissue engineering.
Author: Leszek Adam Dobrza ́ Nski Publisher: Mdpi AG ISBN: 9783036525228 Category : Technology & Engineering Languages : en Pages : 544
Book Description
This book aims to summarize the latest achievements in the development and manufacturing of modern biomaterials used in modern medicine and dentistry, for example, in cases where, as a result of a traffic or sports accident, aging, resection of organs after oncological surgery, or dangerous inflammation, there is a need to replace lost organs, tissues, and parts of the human body. The essence of biomedical materials is their constant contact with living tissues, organisms, or microorganisms and, therefore, they should meet numerous requirements from various fields, including medicine, biology, chemistry, tissue engineering, and materials science. For this reason, biomaterials must be compatible with the organism, and biocompatibility issues must be addressed before using the product in a clinical setting. The production and synthesis of biomaterials require the use of various technologies and methods to obtain the appropriate material, which is then processed using advanced material processing technologies. Often, however, it is necessary to directly manufacture a specific product with individualized geometric features and properties tailored to the requirements of a particular patient. In such cases, additive manufacturing methods are increasingly used. In this sense, it can be considered that the Biomaterials 4.0 stage has been reached, and detailed information is included in the individual chapters of this book on the achievements in the development and manufacturing of modern biomaterials used in modern regenerative medicine, regenerative dentistry, and tissue engineering.
Author: Maria Cristina Tanzi Publisher: Woodhead Publishing ISBN: 0081007434 Category : Technology & Engineering Languages : en Pages : 503
Book Description
Characterization of Polymeric Biomaterials presents a comprehensive introduction on the topic before discussing the morphology and surface characterization of biomedical polymers. The structural, mechanical, and biological characterization is described in detail, followed by invaluable case studies of polymer biomaterial implants. With comprehensive coverage of both theoretical and experimental information, this title will provide scientists with an essential guide on the topic of these materials which are regularly used for clinical applications, such as implants and drug delivery devices. However, a range of novel polymers and the development and modification of existing medical polymers means that there is an ongoing need to satisfy particular design requirements. This book explains the critical and fundamentals methods to characterize polymer materials for biomedical applications. - Presents a self-contained reference on the characterization of polymeric biomaterials - Provides comprehensive information on how to characterize biomedical polymers in order to improve design and synthesis - Includes useful case studies that demonstrate the characterization of biomaterial implants
Author: Mangal Roy Publisher: Elsevier Inc. Chapters ISBN: 0128071036 Category : Science Languages : en Pages : 19
Book Description
In joint replacement surgery with suboptimal bone, allograft materials are often used to achieve biological fixation of the metallic implant to the host bone and reducing the implant fixation time. The most commonly used techniques are cemented and hydroxyapatite (HA)-coated metallic implants. Typically, HA coatings are suggested for patients with better bone stock, whereas recommended implant fixation process for most other osteoporotic patients is bone cements. In general, there is a long-standing need to improve the performance of hip and other devices for longer in vivo implant lifetime that can help in reducing the number of revision surgeries, as well as minimizing physical and mental trauma to the patient. To achieve these goals, it is important to understand the mechanical and biological properties of coatings that can influence not only its short- and long-term bioactivity but also life span in vivo. Over the years, it has been recognized that the stability of a coated implant is governed by its physical and mechanical properties. A coating that separates from the implant provides no advantage over an uncoated implant and undesirable due to problems with debris materials, which can lead to osteolysis. Therefore, it is important to properly characterize the coated implants in terms of its physical and mechanical properties. In this chapter, specific details on coating characterization techniques including sample dimensions, sample preparation, experimental procedure and data interpretation are discussed. In particular, the standards and requirements of regulatory organizations are presented elucidating the significance and use of each characterization. It is important to appreciate that mechanical properties of coatings can only be determined with certain coating specification such as coating thickness. This chapter is designed even for non-experts to follow mechanical property characterizations of coatings on medical implants.
Author: Ravin Narain Publisher: John Wiley & Sons ISBN: 1118776372 Category : Science Languages : en Pages : 934
Book Description
Explores bioconjugate properties and applications of polymers, dendrimers, lipids, nanoparticles, and nanotubes Bioconjugation has enabled breakthroughs across many areas of industry and biomedicine. With its emphasis on synthesis, properties and applications, this book enables readers to understand the connection between chemistry and the biological application of bioconjugated materials. Its detailed descriptions of methods make it possible for researchers to fabricate and take full advantage of bioconjugates for a broad range of applications. Moreover, the book sets the foundation for the development of new applications, including assays, imaging, biosensors, drug delivery, and diagnostics. Chemistry of Bioconjugates features contributions from an international team of leading experts and pioneers in the field. These contributions reflect the authors’ firsthand laboratory experience as well as a thorough review of the current literature. The book’s six sections examine: General methods of bioconjugation Polymer bioconjugates Organic nanoparticle-based bioconjugates Inorganic nanomaterial bioconjugates, including metals and metal oxides Cell-based, hydrogel/microgel, and glyco-bioconjugates Characterization, physico-(bio)chemical properties, and applications of bioconjugates This comprehensive exploration of bioconjugates includes discussions of polymers, dendrimers, lipids, nanoparticles, and nanotubes. References at the end of each chapter serve as a gateway to the most important original research findings and reviews in the field. By drawing together and analyzing all the latest chemical methods and research findings on the physico-chemical and biochemical properties of bioconjugates, Chemistry of Bioconjugates sheds new light on the significance and potential of bioconjugation. The book is recommended for organic and polymer chemists, biochemists, biomaterial scientists, carbohydrate chemists, biophysicists, bioengineers, and drug and gene delivery scientists.
Author: Sangamesh G. Kum bar Publisher: Newnes ISBN: 0123972906 Category : Technology & Engineering Languages : en Pages : 421
Book Description
Polymers are important and attractive biomaterials for researchers and clinical applications due to the ease of tailoring their chemical, physical and biological properties for target devices. Due to this versatility they are rapidly replacing other classes of biomaterials such as ceramics or metals. As a result, the demand for biomedical polymers has grown exponentially and supports a diverse and highly monetized research community. Currently worth $1.2bn in 2009 (up from $650m in 2000), biomedical polymers are expected to achieve a CAGR of 9.8% until 2015, supporting a current research community of approximately 28,000+. Summarizing the main advances in biopolymer development of the last decades, this work systematically covers both the physical science and biomedical engineering of the multidisciplinary field. Coverage extends across synthesis, characterization, design consideration and biomedical applications. The work supports scientists researching the formulation of novel polymers with desirable physical, chemical, biological, biomechanical and degradation properties for specific targeted biomedical applications. - Combines chemistry, biology and engineering for expert and appropriate integration of design and engineering of polymeric biomaterials - Physical, chemical, biological, biomechanical and degradation properties alongside currently deployed clinical applications of specific biomaterials aids use as single source reference on field. - 15+ case studies provides in-depth analysis of currently used polymeric biomaterials, aiding design considerations for the future
Author: Alexandru Grumezescu Publisher: Elsevier ISBN: 0128184345 Category : Technology & Engineering Languages : en Pages : 617
Book Description
Materials for Biomedical Engineering: Organic Micro- and Nanostructures provides an updated perspective on recent research regarding the use of organic particles in biomedical applications. The different types of organic micro- and nanostructures are discussed, as are innovative applications and new synthesis methods. As biomedical applications of organic micro- and nanostructures are very diverse and their impact on modern and future therapy, diagnosis and prophylaxis of diseases is huge, this book presents a timely resource on the topic. Users will find the latest information on cancer and gene therapy, diagnosis, drug delivery, green synthesis of nano- and microparticles, and much more. - Provides knowledge of the range of organic micro- and nanostructures available, enabling the reader to make optimal materials selection decisions - Presents detailed information on current and proposed applications of the latest biomedical materials - Places a strong emphasis on the characterization, production and use of organic nanoparticles in biomedicine, such as gene therapy, DNA interaction and cancer management
Author: Kunal Pal Publisher: Woodhead Publishing ISBN: 0081021801 Category : Technology & Engineering Languages : en Pages : 570
Book Description
Polymeric Gels: Characterization, Properties and Biomedical Applications covers the fundamentals and applications of polymeric gels. Particular emphasis is given to their synthesis, properties and characteristics, with topics such as natural, synthetic, and smart polymeric gels, medical applications, and advancements in conductive and magnetic gels presented. The book covers the basics and applications of hydrogels, providing readers with a comprehensive guide on the types of polymeric gels used in the field of biomedical engineering. - Provides guidance for decisions on the suitability and appropriateness of a synthetic route and characterization technique for particular polymeric networks - Analyzes and compares experimental data - Presents in-depth information on the physical properties of polymeric gels using mathematical models - Uses an interdisciplinary approach to discuss potential new applications for both established polymeric gels and recent advances
Author: Valentina Grumezescu Publisher: Elsevier ISBN: 0128168757 Category : Technology & Engineering Languages : en Pages : 598
Book Description
Materials for Biomedical Engineering: Thermoset and Thermoplastic Polymers presents the newest and most interesting approaches to intelligent polymer engineering in both current and future progress in biomedical sciences. Particular emphasis is placed on the properties needed for each selected polymer and how to increase their biomedical potential in varying applications, such as drug delivery and tissue engineering. These materials are intended for use in diagnoses, therapy and prophylaxis, but are also relatable to other biomedical related applications, such as sensors. Recent developments and future perspectives regarding their use in biomedicine are discussed in detail, making this book an ideal source on the topic. - Highlights the most well-known applications of thermoset and thermoplastic polymers in biological and biomedical engineering - Presents novel opportunities and ideas for developing or improving technologies in materials for companies, those in biomedical industries, and others - Features at least 50% of references from the last 2-3 years
Author: T.S. Sampath Kumar Publisher: Elsevier Inc. Chapters ISBN: 012807096X Category : Science Languages : en Pages : 49
Book Description
The physicochemical properties of biomaterials exert a major influence over their interaction with cells and subsequently play an important role on the materials' in vivo performance . Physical characteristics involve internal microstructural features, shape and size of particles, porosity, density, and surface area. Characterization in terms of the chemistry involves determination of the chemical composition and distribution of the elements within the biomaterial. The last decade has seen several innovations in the armory of tools to image and analyze materials, as well as advancement in the collection and processing of those results. In this chapter, the most commonly used methods, which are available for the microstructural characterization of biomaterials, are explained with suitable examples. This chapter starts with microstructural characterization using different types of microscopic techniques including optical and electron microscopy. These techniques can provide information from atomic-scale to microscale to macroscale information. Specific examples are also used for specialized microscopic techniques such as scanning probe microscopy and atomic force microscopy. Some discussions were also used in -related surface characterization using microscopic techniques. Followed by microscopic techniques, phase analysis techniques are discussed based on X-ray diffraction. Short discussion is also placed on infrared (IR)-based spectroscopic characterization for chemical analysis. Further discussion on IR spectroscopy can be found in for surface analysis. The last part of this chapter deals with size, shape, porosity, surface area and surface energy characterization. Particle size analysis by dynamic light scattering (DLS) is discussed in detail followed by IR spectroscopic analysis. Contact angle measurement for surface energy, mercury intrusion porosimetry for analysis of pore structures and gas adsorption measurements for surface area analysis are presented in detail with relevant examples. Throughout this chapter, specific discussions are focused on examples based on applications as well as advantages, disadvantages, and challenges.
Author: Robert B. Heimann Publisher: Walter de Gruyter GmbH & Co KG ISBN: 3110619318 Category : Science Languages : en Pages : 805
Book Description
This book gives an introduction to the highly interdisciplinary field of biomaterials. It concisely summarizes properties, synthesis and modification of materials such as metals, ceramics, polymers or composites. Characterization, in vitro and in vivo testing as well as a selection of various applications are also part of this inevitable guide.
Author: Leszek Adam Dobrza ́ Nski
Author: Leszek Adam Dobrza ́ Nski
Author: Maria Cristina Tanzi
Author: Mangal Roy
Author: Ravin Narain
Author: Sangamesh G. Kum bar
Author: Alexandru Grumezescu
Author: Kunal Pal
Author: Valentina Grumezescu
Author: T.S. Sampath Kumar
Author: Robert B. Heimann