Author: Paolo FerrariniPublisher:
ISBN:
Category :
Languages : en
Pages : 153
Book Description
Study of Modified Surfaces for Molecular Recognition
Author: Paolo FerrariniCharacterization of the Molecular Basis of Cell Recognition at Surfaces
Author: Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Book Description
Molecular recognition interactions have been studied via atomic force microscopy using specially modified tips. Tip-surface interaction forces in the piconewton range were measured. From the from force-tip separation relationships significant information has been obtained about molecular scale interactions. In particular, analysis of mixed phospholipid/glycolipid bilayers has resulted in a clear understanding of the different forces involved. This work leads to a better understanding of molecular recognition events involving cell adhesion and complex biological reactions, such as healing, and has potential use in ultra sensitive biosensors.
Structure Analysis and Molecular Recognition Studies of Bio-functionalized Surfaces
Author: Publisher:
ISBN: 9789173930505
Category :
Languages : en
Pages : 56
Book Description
Biological and chemical reactions involved in physiological processes are often complex and very sophisticated. Such processes can be mimicked in the laboratory to obtain important knowledge, valuable for the development of new diagnostic methods, drugs and biosensors. This thesis includes investigations of bio-functionalized surfaces that can be used as model systems to mimic naturally existing biomolecular recognition processes.
Molecular Recognition and Inclusion
Author: A.W. ColemanPublisher: Springer Science & Business Media
ISBN: 9401152888
Category : Science
Languages : en
Pages : 552
Book Description
This volume presents articles on the developing field of molecular interactions, molecular recognition, crystal engineering, and structural determination of complex molecular systems. The approaches described are interdisciplinary in nature, reflecting the concept of the ISMRI series of symposia.
Basics of Molecular Recognition
Author: Dipankar ChatterjiPublisher: CRC Press
ISBN: 1482219697
Category : Medical
Languages : en
Pages : 139
Book Description
Basics of Molecular Recognition explores fundamental recognition principles between monomers or macromolecules that lead to diverse biological functions. Based on the author's longtime courses, the book helps readers understand the structural aspects of macromolecular recognition and stimulates further research on whether molecules similar to DNA o
Handbook of Biofunctional Surfaces
Author: Wolfgang KnollPublisher: CRC Press
ISBN: 9814316636
Category : Medical
Languages : en
Pages : 1186
Book Description
The design and synthesis of molecularly or supramolecularly defined interfacial architectures have seen in recent years a remarkable growth of interest and scientific research activities for various reasons. On the one hand, it is generally believed that the construction of an interactive interface between the living world of cells, tissue, or whole organisms and the (inorganic or organic) materials world of technical devices such as implants or medical parts requires proper construction and structural (and functional) control of this organism–machine interface. It is still the very beginning of generating a better understanding of what is needed to make an organism tolerate implants, to guarantee bidirectional communication between microelectronic devices and living tissue, or to simply construct interactive biocompatibility of surfaces in general. This exhaustive book lucidly describes the design, synthesis, assembly and characterization, and bio-(medical) applications of interfacial layers on solid substrates with molecularly or supramolecularly controlled architectures. Experts in the field share their contributions that have been developed in recent years.
Molecular Recognition
Author: Jason A. McEvoyPublisher:
ISBN: 9781611227345
Category : Chemistry
Languages : en
Pages : 0
Book Description
The term 'molecular recognition' refers to the specific interaction between two or more molecules through noncovalent bonding. This book presents research in the study of molecular recognition, including next generation molecular imprinted polymers; applications of molecular imprinting; recent advances in DNA-Ligand molecular recognition and allosteric interactions; the proteomic code and the molecular recognition of odorant-binding proteins in insect olfaction.
The Physical-Organic Chemistry of Surfaces, and Its Relevance to Molecular Recognition
Author: Publisher:
ISBN:
Category :
Languages : en
Pages : 22
Book Description
Understanding the interactions between liquids and the surfaces of organic solids is important for the study of molecular recognition. One method for studying these interactions is based on a physical organic approach: formation of well characterized organic surfaces and comparison of the contact angles of liquids on these surfaces. The technique of self-assembly provides an excellent route for the syntheses of organic surfaces; alkanethiols, for example, self-assemble from solutions to form monolayers on gold. Properties of these monolayers, including their thickness and their wettability by water, can be controlled by manipulating the structure and functionality of the molecules used to form the monolayer. The wettability of monolayers on gold formed from HS(CH2)(n)CH3 or HS(CH2)110(CH2)(n)CH3, where n is the number of methylene groups, depends only on the composition the outermost 5-10 A angstroms of the monolayer. The wettability of monolayers formed from mixtures of HS(CH2)11CH3 and HS(CH2)21CH3 depends both on the structure of the outermost part of the monolayer and the structure of the liquid. These and other results suggest that this physical-organic approach has and will continue to provide valuable insight into molecular recognition. Keywords: Biocompatibility, Proteins, Ligands, Biochemistry. (AW).
Surface Modification to Improve Properties of Materials
Author: Miran MozetičPublisher: MDPI
ISBN: 3038977969
Category : Technology & Engineering
Languages : en
Pages : 356
Book Description
This book contains selected contributions on surface modification to improve the properties of solid materials. The surface properties are tailored either by functionalization, etching, or deposition of a thin coating. Functionalization is achieved by a brief treatment with non-equilibrium gaseous plasma containing suitable radicals that interact chemically with the material surface and thus enable the formation of rather stable functional groups. Etching is performed in order to modify the surface morphology. The etching parameters are selected in such a way that a rich morphology of the surfaces is achieved spontaneously on the sub-micrometer scale, without using masks. The combination of adequate surface morphology and functionalization of materials leads to superior surface properties which are particularly beneficial for the desired response upon incubation with biological matter. Alternatively, the materials are coated with a suitable thin film that is useful in various applications from food to aerospace industries.
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