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Studies Towards the Understanding of the Effects of Ionizing Radiations at the Molecular Scale

Author: Bruno Coupier
Publisher:
ISBN:
Category :
Languages : en
Pages : 277

Book Description
Ce travail s'inscrit dans le cadre d'études récentes pour la compréhension à l'échelle moléculaire des effets des rayonnements ionisants sur les systèmes biologiques, mises en oeuvre par le groupe IPM de l'IPNL en collaboration avec l'Institut für Ionenphysik de l'Université d'Innsbruck. Il est composé de deux parties. La première présente un nouvel ensemble de mesures des sections efficaces d'ionisation de l'hélium par impact de protons ou d'atomes d'hydrogène dans la gamme d'énergie d'intérêt pour la radiobiologie (20 à 150keV). Il s'agit de systèmes modèles d'intérêt pour la compréhension des phénomènes de base, et les collisions H + He ont fait l'objet, jusqu'à présent, de peu d'études utilisant les techniques de coïncidences. En outre, cette étude avec l'hélium a été faite dans l'intention de réaliser un test général de fonctionnement de l'appareillage avant d'aller vers des systèmes plus complexes. Des études similaires ont été ensuite réalisées en remplaçant la cible d'hélium par l'eau ou par des molécules d'intérêt biologique (Uracil, Thymine ...). La seconde partie de la thèse traite d'un autre type de radiations ionisantes que l'on peut voir comme une des conséquences secondaires des radiations étudiées dans la première partie. Des électrons de faible énergie (1 à 16eV) sont émis lors du bombardement de la matière par des protons ou des atomes d'hydrogène rapides; ces électrons ayant à leur tour des effets ionisants sur l'environnement. Une étude de l'attachement dissociatif des électrons sur l'eau a été entreprise à l'université d'Innsbruck, motivée par l'existence d'importants désaccords entre les précédentes études sur le même sujet. Le problème de la discrimination des ions à grande énergie cinétique dans le monochromateur trochoïdal utilisé pour cette étude a fait l'objet d'une attention particulière.

Studies Towards the Understanding of the Effects of Ionizing Radiations at the Molecular Scale

Author: Bruno Coupier
Publisher:
ISBN:
Category :
Languages : en
Pages : 277

Health Risks from Exposure to Low Levels of Ionizing Radiation

Author: Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation
Publisher: National Academies Press
ISBN: 0309133343
Category : Science
Languages : en
Pages : 422

Book Description
This book is the seventh in a series of titles from the National Research Council that addresses the effects of exposure to low dose LET (Linear Energy Transfer) ionizing radiation and human health. Updating information previously presented in the 1990 publication, Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, this book draws upon new data in both epidemiologic and experimental research. Ionizing radiation arises from both natural and man-made sources and at very high doses can produce damaging effects in human tissue that can be evident within days after exposure. However, it is the low-dose exposures that are the focus of this book. So-called “late” effects, such as cancer, are produced many years after the initial exposure. This book is among the first of its kind to include detailed risk estimates for cancer incidence in addition to cancer mortality. BEIR VII offers a full review of the available biological, biophysical, and epidemiological literature since the last BEIR report on the subject and develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation.

Health Effects of Exposure to Low Levels of Ionizing Radiation

Author: National Research Council
Publisher: National Academies
ISBN: 0309039959
Category : Science
Languages : en
Pages : 436

Book Description
This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations.

Holland-Frei Cancer Medicine

Author: Robert C. Bast, Jr.
Publisher: John Wiley & Sons
ISBN: 111900084X
Category : Medical
Languages : en
Pages : 2004

Book Description
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Biological effects of ionizing radiation at the molecular level : Proceedings of the Symposium on the Biological Effects of Ionizing Radiation at the Molecular Level held by the International Atomic Energy Agency at Brno, 2-6 July 1962

Author: Symposium on the Biological Effects of Ionizing Radiation at the Molecular Level
Publisher:
ISBN:
Category :
Languages : en
Pages : 461

Book Description

Medical Effects of Ionizing Radiation

Author: Fred A. Mettler
Publisher: Saunders
ISBN:
Category : Medical
Languages : en
Pages : 484

Book Description
"The new edition of this monograph features renowned experts who offer the most current information and reliable guidance on all aspects of the effects of radiation exposure on humans. They provide the answers you need to effectively treat your patients who have been exposed to accidental, occupational, or medical radiation."--BOOK JACKET.