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Author: Publisher: Academic Press ISBN: 0323915922 Category : Science Languages : en Pages : 392
Book Description
B12 Enzyme, Volume 667 in the Methods in Enzymology serial, highlights new advances in the field with this new volume presenting timely, interesting chapters, including Part I: B12 Biosynthesis and B12 Chaperones, Probing the preference and regioselectivity of lower ligand activation and its role in cobamide diversity, Biosynthesis of corrinoids, The human B12 trafficking chaperones: CblC, CblD and ATR, A method for the efficient adenosylation of corrinoids, Production, purification and liposome reconstitution of cobamide synthase, Extraction and Purification of Cobamides from Bacterial Cultures, Part II: The many faces of B12-dependent enzyme reactions, Methylcobalamin-dependent methionine synthase, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in Methods in Enzymology serials - Includes the latest information on B12 Enzymes
Author: Publisher: Academic Press ISBN: 0323915922 Category : Science Languages : en Pages : 392
Book Description
B12 Enzyme, Volume 667 in the Methods in Enzymology serial, highlights new advances in the field with this new volume presenting timely, interesting chapters, including Part I: B12 Biosynthesis and B12 Chaperones, Probing the preference and regioselectivity of lower ligand activation and its role in cobamide diversity, Biosynthesis of corrinoids, The human B12 trafficking chaperones: CblC, CblD and ATR, A method for the efficient adenosylation of corrinoids, Production, purification and liposome reconstitution of cobamide synthase, Extraction and Purification of Cobamides from Bacterial Cultures, Part II: The many faces of B12-dependent enzyme reactions, Methylcobalamin-dependent methionine synthase, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in Methods in Enzymology serials - Includes the latest information on B12 Enzymes
Author: Bernhard Kräutler Publisher: Wiley-VCH ISBN: Category : Health & Fitness Languages : en Pages : 568
Book Description
This text reviews the important developments in the "B12-field" with regard to biological, chemical, pharmaceutical and medicinal aspects. Topics of particular interest include: biosynthesis of vitamin B12; B12-catalyzed enzymatic reactions and their mechanisms; and structural B12-chemistry
Author: Ivano Bertini Publisher: University Science Books ISBN: 9781891389436 Category : Science Languages : en Pages : 794
Book Description
Part A.: Overviews of biological inorganic chemistry : 1. Bioinorganic chemistry and the biogeochemical cycles -- 2. Metal ions and proteins: binding, stability, and folding -- 3. Special cofactors and metal clusters -- 4. Transport and storage of metal ions in biology -- 5. Biominerals and biomineralization -- 6. Metals in medicine. -- Part B.: Metal ion containing biological systems : 1. Metal ion transport and storage -- 2. Hydrolytic chemistry -- 3. Electron transfer, respiration, and photosynthesis -- 4. Oxygen metabolism -- 5. Hydrogen, carbon, and sulfur metabolism -- 6. Metalloenzymes with radical intermediates -- 7. Metal ion receptors and signaling. -- Cell biology, biochemistry, and evolution: Tutorial I. -- Fundamentals of coordination chemistry: Tutorial II.
Author: Publisher: Academic Press ISBN: 0323955584 Category : Science Languages : en Pages : 386
Book Description
Coenzyme B12 Enzymes, Part B, Volume 169 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on Structural characterization of cobalamin-dependent radical SAM methylases, Purification and characterization of sequential cobalamin-dependent radical SAM methylases ThnK and TokK in -lactam antibiotic biosynthesis, Characterization of the cobalamin-dependent radical S-adenosyl-L-methionine enzyme C-methyltransferase Fom3 in fosfomycin biosynthesis, Studies of OxsB and GenK, two B12-dependent radical SAM enzymes involved in natural product biosynthesis, Purification and structural elucidation of the cobalamin-dependent radical SAM enzyme OxsB, and more. Other chapters discuss Methods for studying the mechanisms of B12 enzymes, Computational investigations of B12 dependent enzymatic reactions, Using kinetic isotope effects to probe the mechanisms of adenosylcobalamin-dependent enzymes, Steady-state and pre-steady state kinetic analysis of ornithine 4,5-aminomutase, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in Methods in Enzymology series - Includes the latest information on B12 Enzymes
Author: Andreas Holzenburg Publisher: Springer Science & Business Media ISBN: 030646828X Category : Science Languages : en Pages : 710
Book Description
Dramatic advances have been made in recent years in the field of redox enzymology which has resulted in an increase of research activities. This volume will cover the recent milestone developments in this field by leading experts, uniting theory and experiment, and selecting contributions to illustrate important aspects of the mechanisms of electron and radical transfer in proteins. Features: A demonstration of the key principles controlling biological redox reactions; Experimental studies of `simple' soluble systems in various enzyme familiies to illustrate concepts in the control of electron transfer reactions; Detail of advances made in membrane electron transfer through structural descriptions of key membrane-embedded proteins; Appeal to those interested in the design and use of redox enzymes, from academics to industrialists.
Author: Hermann Dugas Publisher: Springer Science & Business Media ISBN: 1461224268 Category : Science Languages : en Pages : 717
Book Description
This widely-praised textbook is particularly suited for advanced undergraduates or graduates in chemistry, biochemistry, medicinal chemistry, and pharmacology. The third edition has been substantially revised to reflect new research in the field, and features a major new chapter on self-assembly, auto-organization, and molecular devices. The outstanding figures remain a highlight of the book, and were described in an earlier edition as "the best I've seen for showing the organic chemistry of biomolecules." (Quart. Rev. Biol.)
Author: H. Dugas Publisher: Springer Science & Business Media ISBN: 1468400959 Category : Science Languages : en Pages : 518
Book Description
Springer Advanced Texts in Chemistry New textbooks at all levels of chemistry appear with great regularity. Some fields like basic biochemistry, organic reaction mechanisms, and chemical ther modynamics are well represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. However, some areas of chemistry, especially many of those taught at the graduate level, suffer from a real lack of up-to-date textbooks. The most serious needs occur in fields that are rapidly changing. Textbooks in these subjects usually have to be written by scientists actually involved in the research which is advancing the field. It is not often easy to persuade such individuals to set time aside to help spread the knowledge they have accumulated. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive introductions to their fields. These should serve the needs of one semester or one quarter graduate courses in chemistry and biochemistry. In some cases the availability of texts in active research areas should help stimulate the creation of new courses. New York, New York CHARLES R.
Author: Ruma Banerjee Publisher: John Wiley & Sons ISBN: 9780471253907 Category : Science Languages : en Pages : 960
Book Description
A Definitive New Reference for the Latest Advances in B_12 Chemistry and Biochemistry Over the past decade, the field of B_12 research has been revolutionized by such major breakthroughs as the unraveling of the entire biosynthetic pathway for this important vitamin. This comprehensive compendium surveys the wealth of information that has accumulated, covering in one volume virtually all aspects of the field-from physical and inorganic chemistry to enzymology, microbiology, medicine, and diagnostic and therapeutic applications. Edited by Dr. Ruma Banerjee, a highly respected and active member of the B_12 community, this work provides B_12 researchers with a dependable and up-to-date reference on the subject. Leading authorities from five continents explore such new areas as the structural biology of B_12-dependent enzymes, free-radical-mediated reaction mechanisms, biosynthesis, and much more. The role of B_12 in nutrition and disease, and B_12 transport, are also thoroughly examined. Complete with color illustrations and extensive references, Chemistry and Biochemistry of B_12 is a one-of-a-kind resource for biochemists, biophysicists, spectroscopists, microbiologists, molecular biologists, and anyone with an interest in "nature's most beautiful cofactor."
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Author: Bernhard Kräutler
Author: Zenon Schneider
Author: Ivano Bertini
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Author: Andreas Holzenburg
Author: Hermann Dugas
Author: H. Dugas
Author: N. H. Andersen
Author: Ruma Banerjee