Studies at Moderate Hypothermic Temperatures of Factors Affecting Survival Under Prolonged Hypothermia PDF Download

Author: Boston University. School of Medicine
Publisher:
ISBN:
Category :
Languages : en
Pages : 32

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Author: Boston University. School of Medicine
Publisher:
ISBN:
Category :
Languages : en
Pages : 15

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Author: Evangelos T. Angelakos
Publisher:
ISBN:
Category : Hypothermia
Languages : en
Pages : 14

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The purpose of this investigation was to study the mortality of anesthetized dogs maintained under hypothermia for many hours, and to evaluate the factors responsible for death under these conditions. Data are presented on technically successful experiments in 40 dogs maintained at 26 plus or minus 1 degree C. Among the animals that died during maintained hypothermia mortality was progressive with no apparent critical time. There was a progressive decrease in the average normal pacemaker heart rate in animals maintained at a relatively fixed hypothermic temperature. The factors limiting survival under prolonged hypothermia are different from those involved in the acute induction of the hypothermic state.

Author: E. T. Angelakos
Publisher:
ISBN:
Category :
Languages : en
Pages : 28

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The mortality of anesthetized dogs maintained under prolonged hypothermia was studied and the factors responsible for death were evaluated. In the technically acceptable experiments, 45% of the dogs maintained at moderate hypothermic temperatures (26 plus or minus 1C) died within 16 hours. The corresponding mortality in normothermic (38C) control dogs was 7%. Progressive hemoconcentration and bradycardia were observed during prolonged hypothermia. The former could be abolished by splenectomy. The use of artificial pacemakers to limit the effects of bradycardia was unsuccessful due to the development of other cardiovascular complications. Blood catecholamine levels increased with cooling to 33C but decreased below control levels at or below 25C; however, prolonged hypothermia at 25C was associated with a progressive increase in blood catecholamines up to two to three times the initial control levels. The catecholamine content of aorta, kidney and spleen was not altered significantly by hypothermia, however, cardiac catecholamines decreased to below 50% of control with cooling to 25C. Adrenergic mechanisms apparently play a key role in the alterations of cardiovascular functions which limit survival during prolonged hypothermia. (Author).

Author: Hermann Brugger
Publisher: Edra
ISBN: 8821447340
Category : Medical
Languages : en
Pages : 1331

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Mountain emergency medicine has seen exponential development due to the ever increasing number of people who hike or trek as well as practice extreme sports. Emergency physicians and nurses need to be equipped with the necessary training to be able to manage “on the field” accidents and sicknesses as well as their own physical security. Theoretical knowledge is generally of high level but practical expertise is dangerously lacking in many operators. Furthermore, treatment modalities on the field have not been completely codified and are not supported by internationally-accepted guidelines. This book is the first to offer a complete and thorough approach to this field of Emergency Medicine based on the latest research findings.

Author: Derek Maclean
Publisher: Wiley-Blackwell
ISBN: 9780632008315
Category : Accidents
Languages : en
Pages : 476

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Author: N. Hayashi
Publisher: Springer Science & Business Media
ISBN: 4431668829
Category : Medical
Languages : en
Pages : 253

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Rapid progress in technology and its application to diagnosis and monitoring of brain tissue temperature and metabolism have resulted in advances in the therapy for critically brain-injured patients and breakthroughs in understanding the pathophysiology of brain damage. The latest concept of brain hypothermia therapy clarifies targets such as brain thermal pooling, masking brain hypoxia associated with catecholamine surge, the metabolic shift from glucose to lipids, and selective radical damage of dopamine in the central nervous system. This volume explains the mechanism of brain injury and how brain hypothermia treatment differs from other hypothermia therapy in four major sections: Brain Injury Mechanism, Pathophysiology of Hypothermia, Basic Research of Hypothermia Treatment, and Clinical Studies of Brain Hypothermia. The book is a valuable source for practitioners and researchers in neurosurgery and neurology and in critical care and emergency medicine.

Author: Peter Safar
Publisher: W.B. Saunders Company
ISBN: 9780721621562
Category : Medical
Languages : en
Pages : 488

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An introduction to basic and advanced cardiac and trauma life support. This text embodies the principles and practices advocated by the World Federation of Societies of Anaesthesiologists' Committee on Cardiopulmonary Cerebral Resusitation and Critical Care and incorporates American Heart Association Conference guidelines on CPR and emergency care. Includes complete coverage of resuscitation medicine--basic, advanced and prolonged cardiac and traumatic life support. Approved by the WFSA.

Author: Hemanshu Prabhakar
Publisher: Academic Press
ISBN: 0128041137
Category : Medical
Languages : en
Pages : 502

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Complications in Neuroanesthesia focuses on complications that may arise related to neuroanesthesia practice and discusses its various causes. Each complication is written as a separate chapter, and the pathophysiology and mechanisms of each complication, as well as measures for diagnosis, treatment and prevention are discussed. Towards the end of the book, several case scenarios are provided to the readers that challenge readers to diagnose the possible complication for each case. Chapters include brain and spinal cord problems, cardiovascular and hematological problems, and nerve and muscle problems. Written in a standard format, Complications in Neuroanesthesia provides quick and easy access to understanding problems in neuroanesthesia. It provides insight into all possible complications occurring during perioperative management of neurosurgical and neurologic patients. It is useful for trainees, clinicians, and researchers in the fields of neurosurgery, neurocritical care, and neurology by providing an understanding of preventable mishaps that may occur in neurosurgical or neurologic patients. - Quick and easy reference for understanding problems in neuroanesthesia - Provides comprehensive insights into all possible complications occurring during perioperative management of neurosurgical and neurologic patients - Includes useful section with clinical case studies of complications in neuroanesthesia

Author: M. Kosaka
Publisher: Springer Science & Business Media
ISBN: 4431670351
Category : Medical
Languages : en
Pages : 556

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This book provides a comprehensive overview of the multitude of different forms of thermotherapy in connection with aspects of thermal physiology and cell biology. The aim is to elucidate the scientific background of therapeutic actions and to promote effective new applications at the beginning of the 21st century. Significant to these purposes is cooperation between experts in the fields of thermal biology, hyper thermic oncology, rheumatology, and balneology, as represented by the editors. Emphasis has been placed on a balanced choice of contributions, in the hope that this will enable the reader to draw helpful connections between the principles and prac tice of thermotherapy. It is apparent that a wealth of published data exists concerning thermotherapy on the one hand and thermal physiology on the other. However, in the former field empirical aspects of therapeutic usefulness prevail, while in the latter, aspects of basic science are in the foreground. Accordingly, the sources where published data may be found are quite different and as a consequence many findings of potential mutual interest published in medical journals have gone unnoticed by readers of physio logical journals, and vice versa. It is hoped that this book will bridge the gap and encourage researchers' efforts to integrate the available knowledge to attain optimal coordination of clinical and theoretical aspects.