Structure Formation as Studied by EPR Spectroscopy PDF Download

Author: Jeannine Heller
Publisher:
ISBN:
Category :
Languages : en
Pages : 380

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Author: Matthias J.N.Junk
Publisher: Springer Science & Business Media
ISBN: 3642251358
Category : Technology & Engineering
Languages : en
Pages : 225

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Book Description
In his thesis, Matthias Junk takes an innovative approach to assess the local structure and dynamics of biological and synthetic amphiphilic macromolecules capable of transporting small molecules. Replacing the latter with stable radicals, he uses state-of-the-art electron paramagnetic resonance (EPR) spectroscopy to describe the highly relevant transport function from the viewpoint of the guest molecules. Such, he demonstrates that the functional structure of human serum albumin in solution significantly differs from its crystal structure – a consequence of the protein’s adaptability to host various endogenous compounds and drug molecules. Further, he shows that the thermal collapse of thermoresponsive hydrogels and dendronized polymers leads to static and dynamic heterogeneities on the nanoscale. These heterogeneities bear consequences for the material’s hosting properties and enable unforeseen complex catalytic functionalities.

Author: Chandran Karunakaran
Publisher: Elsevier
ISBN: 012813609X
Category : Science
Languages : en
Pages : 380

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Book Description
Spin Resonance Spectroscopy: Principles and Applications presents the principles, recent advancements and applications of nuclear magnetic resonance (NMR) and electron paramagnetic resonance (EPR) in a single multi-disciplinary reference. Spin resonance spectroscopic techniques through NMR and EPR are widely used by chemists, physicists, biologists and medicinal chemists. This book addresses the need for new spin resonance spectroscopy content while also presenting the principles, recent advancements and applications of NMR and EPR simultaneously. Ideal for researchers and students alike, the book provides a single source of NMR and EPR applications using a dynamic, holistic and multi-disciplinary approach. Presents a highly interdisciplinary approach by including NMR and EPR applications in chemistry, physics, biology and biotechnology Addresses both NMR and EPR, making its concepts and applications implementable in multiple resonance environments and core scientific disciplines Features a broad range of methods, examples and illustrations for both NMR and EPR to aid in retention and underscore key concepts

Author: Anders Lund
Publisher: Springer
ISBN: 3319092162
Category : Science
Languages : en
Pages : 766

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Book Description
Applications of EPR in Radiation Research is a multi-author contributed volume presented in eight themes: I. Elementary radiation processes (in situ and low temperature radiolysis, quantum solids); II: Solid state radiation chemistry (crystalline, amorphous and heterogeneous systems); III: Biochemistry, biophysics and biology applications (radicals in biomaterials, spin trapping, free-radical-induced DNA damage); IV: Materials science (polymeric and electronic materials, materials for treatment of nuclear waste, irradiated food); V: Radiation metrology (EPR-dosimetry, retrospective and medical applications); VI: Geological dating; VII: Advanced techniques (PELDOR, ESE and ENDOR spectroscopy, matrix isolation); VIII: Theoretical tools (density-functional calculations, spectrum simulations).

Author: Anders Lund
Publisher: Springer Science & Business Media
ISBN: 9400748876
Category : Science
Languages : en
Pages : 400

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EPR of Free Radicals in Solids: Trends in Methods and Applications, 2nd ed. presents a critical two volume review of the methods and applications of EPR (ESR) for the study of free radical processes in solids. Emphasis is on the progress made in the developments in EPR technology, in the application of sophisticated matrix isolation techniques and in the advancement in quantitative EPR that have occurred since the 1st edition was published. Improvements have been made also at theoretical level, with the development of methods based on first principles and their application to the calculation of magnetic properties as well as in spectral simulations. EPR of Free Radicals in Solids II focuses on the trends in applications of experimental and theoretical methods to extract structural and dynamical properties of radicals and spin probes in solid matrices by continuous wave (CW) and pulsed techniques in nine chapters written by experts in the field. It examines the studies involving radiation- and photo-induced inorganic and organic radicals in inert matrices, the high-spin molecules and metal-based molecular clusters as well as the radical pro-cesses in photosynthesis. Recent advancements in environmental applications in-cluding measurements by myon resonance of radicals on surfaces and by quantitative EPR in dosimetry are outlined and the applications of optical detection in material research with much increased sensitivity reviewed. The potential use of EPR in quantum computing is considered in a newly written chapter. This new edition is aimed to experimentalists and theoreticians in research involving free radicals, as well as for students of advanced courses in physical chemis-try, chemical physics, materials science, biophysics, biochemistry and related fields.

Author: Ellen C. Hayes
Publisher:
ISBN:
Category :
Languages : en
Pages : 294

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Book Description
In this dissertation, the fundamental concepts and techniques of electron paramagnetic resonance (EPR) spectroscopy, which are important for understanding electronic structure and relating it to geometric structure, are presented in Chapter 1. Following this are five chapters each dedicated to a separate topic where EPR spectroscopy was a central tool in studying the properties of biologically relevant systems. Chapter 2 focuses on the study of tryptophan radicals in small peptide systems. The studies aim to understand how microenvironment influences the electronic structure (through measuring magnetic and electrochemical properties) of these radicals. In Chapter 3, the identity of an unknown organic radical in the active site of the enzyme spore photoproduct lyase (SPL) is investigated. This radical is believed to be a part of a radical transfer chain involved in the repair of photodamaged DNA by the enzyme SPL. In Chapter 4, closely related to the topics of Chapter 3, the pathway of DNA photodamage by ultraviolet light is investigated. The damaged DNA is believed to form through a radical recombination process amenable to study with EPR spectroscopy. Chapter 5 discusses the magnetic properties of an intermediate formed during O-O bond activation and cleavage by a small molecule MnII compound. Results of EPR spectroscopy suggest the intermediate is a MnIIIMnIV dimer and aim to characterize the bridging motif and protonation state of the MnIIIMnIV dimer. Finally, Chapter 6 presents a study of a small molecule CuII-alkoxide compound relevant for understanding CuII mediated alcohol oxidations (which occur in enzymes such as galactose oxidase). A detailed electronic structure characterization was carried out by using single-crystal EPR spectroscopy in tandem with magnetic circular dichroism spectroscopy, resonance Raman spectroscopy, and density functional theory calculations.

Author: Bela E. Bode
Publisher: Royal Society of Chemistry
ISBN: 183916171X
Category : Science
Languages : en
Pages : 277

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Book Description
Electron paramagnetic resonance (EPR) applications remain highly significant in modern analytical science and this volume compiles critical coverage of developments in the recent literature. The topics covered in this volume describe contrasting types of EPR application, including rapid scan EPR, using the EPR toolkit to investigate the structural dynamics of membrane proteins and pulse dipolar EPR spectroscopy for investigating biomolecular binding events. An additional chapter reviewing the PARACAT collaboration from the EU has also been included. Providing a snapshot of the area by a handpicked group of researchers at the cutting-edge of the field, this book is a useful addition to any library supporting this research.

Author: Wilfred Raymond Hagen
Publisher: CRC Press
ISBN: 1420059580
Category : Medical
Languages : en
Pages : 264

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Book Description
Comprehensive, Up-to-Date Coverage of Spectroscopy Theory and its Applications to Biological SystemsAlthough a multitude of books have been published about spectroscopy, most of them only occasionally refer to biological systems and the specific problems of biomolecular EPR (bioEPR). Biomolecular EPR Spectroscopy provides a practical introduction t

Author: Patrick Bertrand
Publisher: Springer Nature
ISBN: 3030396681
Category : Science
Languages : en
Pages : 433

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Book Description
This book shows how the fundamentals of electron paramagnetic resonance (EPR) spectroscopy are practically implemented and illustrates the diversity of current applications. The technique is used at various levels, and applications are presented in order of increasing difficulty, with reference to theoretically obtained results. This book features a diverse array of application examples, from fields such as ionizing radiation dosimetry, neurodegenerative diseases, structural transitions in proteins, and the origins of terrestrial life. The final chapter of this book highlights the principles and applications of the technique of ferromagnetic resonance spectroscopy, followed by a brief introduction to advanced EPR techniques such as electron spin echo envelope modulation (ESEEM), hyperfine sub-level correlation (HYSCORE), pulsed electron-electron double resonance (PELDOR), and continuous wave electron nuclear double resonance (ENDOR) experiments.

Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1064

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