Author: Amanda Lizabeth SalmonPublisher:
ISBN:
Category :
Languages : en
Pages : 0
Book Description
Structural and Functional Characterisation of Bioactive Amphibian Skin Peptides
Author: Amanda Lizabeth SalmonPublisher:
ISBN:
Category :
Languages : en
Pages : 0
Book Description
Molecular Cloning, Structural Characterisation and Functional Study of Bioactive Peptides from Amphibian Skin Secretion
Author: Yuqing ChenDiscovery, Structural Characterisation and Targeted Engineering of Bioactive Peptides from Amphibian Skin Secretion
Author: Haoyang HeIdentification, Molecular Cloning and Functional Characterization of Novel Bioactive Peptides from Amphibian Skin Secretion
Author: Yanjing DongIdentification, Molecular Cloning and Functional Characterisation of Novel Bioactive Peptide Drugs from Amphibian Skin Secretions
Author: Dong ChenMarine Bioactive Peptides: Structure, Function, and Therapeutic Potential
Author: Tatiana V. Ovchinnikova Publisher: MDPI
ISBN: 3039215329
Category : Medical
Languages : en
Pages : 442
Book Description
This Special Issue Book, “Marine Bioactive Peptides: Structure, Function, and Therapeutic Potential" includes up-to-date information regarding bioactive peptides isolated from marine organisms. Marine peptides have been found in various phyla, and their numbers have grown in recent years. These peptides are diverse in structure and possess broad-spectrum activities that have great potential for medical applications. Various marine peptides are evolutionary ancient molecular factors of innate immunity that play a key role in host defense. A plethora of biological activities, including antibacterial, antifungal, antiviral, anticancer, anticoagulant, endotoxin-binding, immune-modulating, etc., make marine peptides an attractive molecular basis for drug design. This Special Issue Book presents new results in the isolation, structural elucidation, functional characterization, and therapeutic potential evaluation of peptides found in marine organisms. Chemical synthesis and biotechnological production of marine peptides and their mimetics is also a focus of this Special Issue Book.
Molecular Cloning, Structural Characterisation and Functional Study of Bioactive Peptides from Odorrana Versabilis Skin Secretion
Author: Junting YaoIdentification and Functional Characterization of Novel Venom Components
Author: Steven D. AirdPublisher: MDPI
ISBN: 3039364677
Category : Science
Languages : en
Pages : 210
Book Description
Throughout most of the 20th century, the toxinological literature consisted largely of pharmacological and functional characterizations of crude venoms and venom constituents, often constituents that could not be identified unambiguously. The advent of amino acid composition analysis in the 1950s enabled the first forays into physical characterizations of purified toxins, though these remained few in number until the 1970s. Then, the tryptic and chymotryptic cleavage of venom proteins coupled with manual Edman degradation began to provide the first complete sequences, particularly of three-finger toxins. Polyacrylamide gel electrophoresis and improved resins for liquid chromatography permitted improved purification and better gross structural characterization of venom components. The early 1980s witnessed the advent of automated Edman degradation, and entire sequences of longer proteins began to be reported in the literature. Then, the molecular biology revolution enabled the generation of cDNA sequences of more and larger proteins, followed by mass-spectrometry-based proteomics and quantitative high-throughput DNA sequencing and genomics. Today, we face an unprecedented situation in which our capacity to generate sequence/structural data has completely overwhelmed our capacity to functionally characterize venom constituents. This Special Issue of Toxins includes 11 publications addressing the discovery and functional characterization of novel venom constituents of vertebrate and invertebrate venoms.
Handbook of Biologically Active Peptides
Author: Abba KastinPublisher: Academic Press
ISBN: 0123850967
Category : Science
Languages : en
Pages : 2033
Book Description
Handbook of Biologically Active Peptides, Second Edition, is the definitive, indispensable reference for peptide researchers, biochemists, cell and molecular biologists, neuroscientists, pharmacologists, and endocrinologists. Its chapters are designed to be a source for workers in the field and enable researchers working in a specific area to examine related areas outside their expertise. Peptides play a crucial role in many physiological processes, including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology, and cell biology. The second edition of Handbook of Biologically Active Peptides presents this tremendous body of knowledge in the field of biologically active peptides in one single reference. The section editors and contributors represent some of the most sophisticated and distinguished scientists working in basic sciences and clinical medicine. - Presents all aspects of biologically active peptides in one resource - Features more than 20 sections spanning plant, bacterial, fungal, venom, and invertebrate peptides to general peptides - Includes immunological, inflammatory, cancer, vaccine, and neurotrophic peptides - Discusses peptide precursors, mRNA distribution, processing, and receptors, not just pathophysiological implications
Structural and Mechanistic Studies of Bioactive Peptides
Author: Tara Louise PukalaPublisher:
ISBN:
Category : Amphibians
Languages : en
Pages : 668
Book Description
The research presented in this thesis is centred on the isolation and investigation of peptides from both frogs and spiders, and endeavours to probe the important structural and mechanistic features of these bioactive compounds. The skin peptide profiles of interspecific hybrids between the green tree frog Litoria caerulea and the magnificent tree frog Litoria splendida have been investigated in a nine-month survey. Fourteen peptides were characterised primarily using mass spectrometry, of which three had not been identified previously in the skin secretions of either parent.