Statistical Bases of Reference Values in Laboratory Medicine PDF Download

Author: Eugene K. Harris
Publisher: CRC Press
ISBN: 9780824793395
Category : Mathematics
Languages : en
Pages : 388

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Book Description
Examining the strengths and limitations of various standards of accuracy in clinical laboratory analyses, this detailed reference presents an in-depth study of important theoretical and empirical issues concerning the description, collection, and application of reference values in laboratory medicine.

Author: P. W. Strike
Publisher: Butterworth-Heinemann
ISBN: 1483161927
Category : Medical
Languages : en
Pages : 553

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Book Description
Statistical Methods in Laboratory Medicine focuses on the application of statistics in laboratory medicine. The book first ponders on quantitative and random variables, exploratory data analysis (EDA), probability, and probability distributions. Discussions focus on negative binomial distribution, non-random distributions, binomial distribution, fitting the binomial model to sample data, conditional probability and statistical independence, rules of probability, and Bayes' theorem. The text then examines inference, regression, and measurement and control. Topics cover analytical goals for assay precision, estimating the error variance components, indirect structural assays, functional assays, bivariate regression model, and least-squares estimates of the functional relation parameters. The manuscript takes a look at assay method comparison studies, multivariate analysis, forecasting and control, and test interpretation. Concerns include time series structure and terminology, polynomial regression, assessing the performance of the classification rule, quantitative screening tests, sample correlation coefficient, and computer assisted diagnosis. The book is a dependable reference for medical experts and statisticians interested in the employment of statistics in laboratory medicine.

Author: D. A. Berry
Publisher: CRC Press
ISBN: 1482276860
Category : Mathematics
Languages : en
Pages : 592

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Book Description
A state-of-the-art handbook of statistical analysis for use in the pharmaceutical industry. Areas covered in this reference/text include: bioavailability, repeated-measures designs, dose-response, population models, multicenter trials, handling dropouts, survival analysis, robust data analysis, cate

Author: Callum G. Fraser
Publisher: Amer. Assoc. for Clinical Chemistry
ISBN: 9781890883492
Category : Medical
Languages : en
Pages : 172

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Book Description

Author: William Q. Meeker
Publisher: John Wiley & Sons
ISBN: 1118594959
Category : Mathematics
Languages : en
Pages : 648

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Book Description
Describes statistical intervals to quantify sampling uncertainty,focusing on key application needs and recently developed methodology in an easy-to-apply format Statistical intervals provide invaluable tools for quantifying sampling uncertainty. The widely hailed first edition, published in 1991, described the use and construction of the most important statistical intervals. Particular emphasis was given to intervals—such as prediction intervals, tolerance intervals and confidence intervals on distribution quantiles—frequently needed in practice, but often neglected in introductory courses. Vastly improved computer capabilities over the past 25 years have resulted in an explosion of the tools readily available to analysts. This second edition—more than double the size of the first—adds these new methods in an easy-to-apply format. In addition to extensive updating of the original chapters, the second edition includes new chapters on: Likelihood-based statistical intervals Nonparametric bootstrap intervals Parametric bootstrap and other simulation-based intervals An introduction to Bayesian intervals Bayesian intervals for the popular binomial, Poisson and normal distributions Statistical intervals for Bayesian hierarchical models Advanced case studies, further illustrating the use of the newly described methods New technical appendices provide justification of the methods and pathways to extensions and further applications. A webpage directs readers to current readily accessible computer software and other useful information. Statistical Intervals: A Guide for Practitioners and Researchers, Second Edition is an up-to-date working guide and reference for all who analyze data, allowing them to quantify the uncertainty in their results using statistical intervals.

Author: Gerald J. Hahn
Publisher: John Wiley & Sons
ISBN: 0470317442
Category : Mathematics
Languages : en
Pages : 423

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Book Description
Presents a detailed exposition of statistical intervals and emphasizes applications in industry. The discussion differentiates at an elementary level among different kinds of statistical intervals and gives instruction with numerous examples and simple math on how to construct such intervals from sample data. This includes confidence intervals to contain a population percentile, confidence intervals on probability of meeting specified threshold value, and prediction intervals to include observation in a future sample. Also has an appendix containing computer subroutines for nonparametric statistical intervals.

Author: Shein-Chung Chow
Publisher: CRC Press
ISBN: 9780203910146
Category : Mathematics
Languages : en
Pages : 412

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Book Description
Emphasizing the role of good statistical practices (GSP) in drug research and formulation, this book outlines important statistics applications for each stage of pharmaceutical development to ensure the valid design, analysis, and assessment of drug products under investigation and establish the safety and efficacy of pharmaceutical compounds. Cove

Author: Michiko Watanabe
Publisher: CRC Press
ISBN: 0824757025
Category : Mathematics
Languages : en
Pages : 214

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Book Description
Exploring the application and formulation of the EM algorithm, The EM Algorithm and Related Statistical Models offers a valuable method for constructing statistical models when only incomplete information is available, and proposes specific estimation algorithms for solutions to incomplete data problems. The text covers current topics including statistical models with latent variables, as well as neural network models, and Markov Chain Monte Carlo methods. It describes software resources valuable for the processing of the EM algorithm with incomplete data and for general analysis of latent structure models of categorical data, and studies accelerated versions of the EM algorithm.

Author: Nader Rifai
Publisher: Elsevier Health Sciences
ISBN: 0323834671
Category : Medical
Languages : en
Pages : 4232

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Book Description
Use THE definitive reference for laboratory medicine and clinical pathology! Tietz Textbook of Laboratory Medicine, 7th Edition provides the guidance necessary to select, perform, and evaluate the results of new and established laboratory tests. Comprehensive coverage includes the latest advances in topics such as clinical chemistry, genetic metabolic disorders, molecular diagnostics, hematology and coagulation, clinical microbiology, transfusion medicine, and clinical immunology. From a team of expert contributors led by Nader Rifai, this reference includes access to wide-ranging online resources on Expert Consult — featuring the comprehensive product with fully searchable text, regular content updates, animations, podcasts, over 1300 clinical case studies, lecture series, and more. - Authoritative, current content helps you perform tests in a cost-effective, timely, and efficient manner; provides expertise in managing clinical laboratory needs; and shows how to be responsive to an ever-changing environment. - Current guidelines help you select, perform, and evaluate the results of new and established laboratory tests. - Expert, internationally recognized chapter authors present guidelines representing different practices and points of view. - Analytical criteria focus on the medical usefulness of laboratory procedures. - Use of standard and international units of measure makes this text appropriate for any user, anywhere in the world. - Elsevier eBooks+ provides the entire text as a fully searchable eBook, and includes animations, podcasts, more than 1300 clinical case studies, over 2500 multiple-choice questions, a lecture series, and more, all included with print purchase. - NEW! 19 additional chapters highlight various specialties throughout laboratory medicine. - NEW! Updated, peer-reviewed content provides the most current information possible. - NEW! The largest-ever compilation of clinical cases in laboratory medicine is included with print purchase on Elsevier eBooks+. - NEW! Over 100 adaptive learning courses included with print purchase on Elsevier eBooks+ offer the opportunity for personalized education.

Author: Alan H. B. Wu
Publisher: Elsevier Health Sciences
ISBN: 1437719872
Category : Medical
Languages : en
Pages : 1857

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Book Description
This new edition of Norbert Tietz's classic handbook presents information on common tests as well as rare and highly specialized tests and procedures - including a summary of the utility and merit of each test. Biological variables that may affect test results are discussed, and a focus is placed on reference ranges, diagnostic information, clinical interpretation of laboratory data, interferences, and specimen types. New and updated content has been added in all areas, with over 100 new tests added. - Tests are divided into 8 main sections and arranged alphabetically. - Each test includes necessary information such as test name (or disorder) and method, specimens and special requirements, reference ranges, chemical interferences and in vivo effects, kinetic values, diagnostic information, factors influencing drug disposition, and clinical comments and remarks. - The most current and relevant tests are included; outdated tests have been eliminated. - Test index (with extensive cross references) and disease index provide the reader with an easy way to find necessary information - Four new sections in key areas (Preanalytical, Flow Cytometry, Pharmacogenomics, and Allergy) make this edition current and useful. - New editor Alan Wu, who specializes in Clinical Chemistry and Toxicology, brings a wealth of experience and expertise to this edition. - The Molecular Diagnostics section has been greatly expanded due to the increased prevalence of new molecular techniques being used in laboratories. - References are now found after each test, rather than at the end of each section, for easier access.