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Spontaneous Activity in the Sensory System

Spontaneous Activity in the Sensory System PDF Author: Kazuo Imaizumi
Publisher: Frontiers Media SA
ISBN: 2889454789
Category :
Languages : en
Pages : 152

Book Description
Spontaneous activity in the nervous system is defined as neural activity that is not driven by an external stimulus and is considered a problem for sensory processing and computation. However, spontaneous activity is not completely random and often has unique spatiotemporal patterns that instruct neural circuit development in the developing brain. Moreover, normal and aberrant patterns of spontaneous activity underlie behavioral states and diseased conditions in the adult brain. The recent technological development has shed light on these unique questions in spontaneous activity. This eBook provides both original and review articles in the propensity, mechanisms, and functions of spontaneous activity in the sensory system. Our goal is to define the state of knowledge in the field, the current challenges, and the future directions for research.

Spontaneous Activity in the Sensory System

Spontaneous Activity in the Sensory System PDF Author: Kazuo Imaizumi
Publisher: Frontiers Media SA
ISBN: 2889454789
Category :
Languages : en
Pages : 152

Book Description
Spontaneous activity in the nervous system is defined as neural activity that is not driven by an external stimulus and is considered a problem for sensory processing and computation. However, spontaneous activity is not completely random and often has unique spatiotemporal patterns that instruct neural circuit development in the developing brain. Moreover, normal and aberrant patterns of spontaneous activity underlie behavioral states and diseased conditions in the adult brain. The recent technological development has shed light on these unique questions in spontaneous activity. This eBook provides both original and review articles in the propensity, mechanisms, and functions of spontaneous activity in the sensory system. Our goal is to define the state of knowledge in the field, the current challenges, and the future directions for research.

Spontaneous Firing of Sensory Neurons Modulates the Gain in the Downstream Circuit of a Simple Olfactory System

Spontaneous Firing of Sensory Neurons Modulates the Gain in the Downstream Circuit of a Simple Olfactory System PDF Author: Matthew Justin O'Neill
Publisher:
ISBN:
Category : Electronic dissertations
Languages : en
Pages : 63

Book Description
In locusts and other insects, odorants are transduced into electrical signal by the olfactory receptor neurons and transmitted to central circuits for further processing. Previous studies have shown that exogenous variables (e.g., flow rates, humidity, temperature, odor mixtures, etc.) can influence the responses of the sensory neurons and therefore modulate the central circuits. However, how the sensory neuron activity is manipulated to achieve adaptive gain control in the following circuit is yet to be understood. It is possible that the magnitude of the stimulus-evoked response in the receptor neurons, their spontaneous activity, or both of these factors can change how information about a chemical cue is processed downstream. To this end, I studied the effects of modulating two different factors on the olfactory system (flow rate and relative humidity) at four levels of the olfactory system: individual olfactory receptor neurons (first-order neurons), the whole antenna (electroantennogram recordings), individual projection neurons in the antennal lobe of the brain (second-order neurons), and population antennal lobe activity as assayed by local field potential recordings in the mushroom body. We found that flow rate changes altered the magnitude of the stimulus-evoked responses in the antenna without altering the spontaneous activity levels. Whereas, changes in the relative humidity elicited a decrease in both response magnitude and baseline activity. Intriguingly, only the humidity modulation experiments brought about significant compensatory change in the spontaneous and odor-evoked activity of the second-order neurons in the antennal lobe. Therefore, our data and analysis suggest that baseline activity of receptor neurons seems to play a key role in adapting the gain of the locust brain's central circuit.

Spontaneous Activity and Sensory Integration in Cerbellar Neurons in Vivo

Spontaneous Activity and Sensory Integration in Cerbellar Neurons in Vivo PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 350

Book Description


Development of the Visual System

Development of the Visual System PDF Author: Retina Research Foundation (U.S.). Symposium
Publisher: MIT Press
ISBN: 9780262121545
Category : Neuroreguladores
Languages : en
Pages : 330

Book Description
Development of the Visual System presents a selection of current studies that clearly illustrate principles of visual system development. These range from retinal development in fish and frogs to the effects of abnormal visual experience on the primary visual cortex of the cat. The book is unique in addressing four specific and fundamental aspects of development: cell lineage and cell fate, specificity and targeting of axons, specification of visual cortex, and correlates of the critical period. Encompassing technical advances in cellular and molecular biology and in video imaging and microscopy, contributions in each of these areas provide new information at the cellular and molecular levels to complement the now classic descriptions of visual development previously available at the level of neural systems.ContributorsKaren L. Allendoerfer, David M. Altshuler, Antonella Antonini, Seymour Benzer, Edward M. Callaway, Constance L. Cepko, Hollis T. Cline, Max S. Cynader, N. W. Daw, Scott E. Fraser, K. Fox, Eckhard Friauf, Anirvan Ghosh, R. W. Guillery, William A. Harris, Christine E. Holt, Lawrence C. Katz, Susan McConnell, Pamela A. Raymond, Thomas A. Reh, Carla J. Shatz, Michael P. Stryker, Claudia A. 0. Stuermer, Mriganka Sur, David L. Turner, T. N. Wiesel

Brain Architecture : Understanding the Basic Plan

Brain Architecture : Understanding the Basic Plan PDF Author: and Director NIBS Neuroscience Program University of Southern California Larry W. Swanson Milo Don and Lucille Appleman Professor of Biological Sciences
Publisher: Oxford University Press, USA
ISBN: 0198026463
Category : Medical
Languages : en
Pages : 283

Book Description
Depending on your point of view the brain is an organ, a machine, a biological computer, or simply the most important component of the nervous system. How does it work as a whole? What are its major parts and how are they interconnected to generate thinking, feelings, and behavior? This book surveys 2,500 years of scientific thinking about these profoundly important questions from the perspective of fundamental architectural principles, and then proposes a new model for the basic plan of neural systems organization based on an explosion of structural data emerging from the neuroanatomy revolution of the 1970's. The importance of a balance between theoretical and experimental morphology is stressed throughout the book. Great advances in understanding the brain's basic plan have come especially from two traditional lines of biological thought-- evolution and embryology, because each begins with the simple and progresses to the more complex. Understanding the organization of brain circuits, which contain thousands of links or pathways, is much more difficult. It is argued here that a four-system network model can explain the structure-function organization of the brain. Possible relationships between neural networks and gene networks revealed by the human genome project are explored in the final chapter. The book is written in clear and sparkling prose, and it is profusely illustrated. It is designed to be read by anyone with an interest in the basic organization of the brain, from neuroscience to philosophy to computer science to molecular biology. It is suitable for use in neuroscience core courses because it presents basic principles of the structure of the nervous system in a systematic way.

The Neurobiology of Olfaction

The Neurobiology of Olfaction PDF Author: Anna Menini
Publisher: CRC Press
ISBN: 1420071998
Category : Science
Languages : en
Pages : 438

Book Description
Comprehensive Overview of Advances in OlfactionThe common belief is that human smell perception is much reduced compared with other mammals, so that whatever abilities are uncovered and investigated in animal research would have little significance for humans. However, new evidence from a variety of sources indicates this traditional view is likely

Neural Circuit and Cognitive Development

Neural Circuit and Cognitive Development PDF Author: Bin Chen
Publisher: Academic Press
ISBN: 0128144122
Category : Psychology
Languages : en
Pages : 670

Book Description
Neural Circuit and Cognitive Development, Second Edition, the latest release in the Comprehensive Developmental Neuroscience series, provides a much-needed update to underscore the latest research in this rapidly evolving field, with new section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume is devoted mainly to anatomical and functional development of neural circuits and neural systems and cognitive development. Understanding the critical role these changes play in neurodevelopment provides the ability to explore and elucidate the underlying causes of neurodevelopmental disorders and their effect on cognition. This series is designed to fill the knowledge gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Features leading experts in various subfields as section editors and article authors Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship Includes coverage of mechanisms that control the assembly of neural circuits in specific regions of the nervous system and multiple aspects of cognitive development

The Mammalian Auditory Pathway: Neuroanatomy

The Mammalian Auditory Pathway: Neuroanatomy PDF Author: Douglas B Webster
Publisher: Springer Science & Business Media
ISBN: 1461244161
Category : Science
Languages : en
Pages : 494

Book Description
The Springer Handbook of Auditory Research presents a series of com prehensive and synthetic reviews of the fundamental topics in modem auditory research. It is aimed at all individuals with interests in hearing research including advanced graduate students, postdoctoral researchers, and clinical investigators. The volumes will introduce new investigators to important aspects of hearing science and will help established inves tigators to better understand the fundamental theories and data in fields of hearing that they may not normally follow closely. Each volume is intended to present a particular topic comprehensively, and each chapter will serve as a synthetic overview and guide to the literature. As such, the chapters present neither exhaustive data reviews nor original research that has not yet appeared in peer-reviewed journals. The series focusses on topics that have developed a solid data and con ceptual foundation rather than on those for which a literature is only beginning to develop. New research areas will be covered on a timely basis in the series as they begin to mature.

Methods of Behavior Analysis in Neuroscience

Methods of Behavior Analysis in Neuroscience PDF Author: Jerry J. Buccafusco
Publisher: CRC Press
ISBN: 1420041819
Category : Medical
Languages : en
Pages : 341

Book Description
Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic

The Auditory Cortex

The Auditory Cortex PDF Author: Jeffery A. Winer
Publisher: Springer Science & Business Media
ISBN: 1441900748
Category : Science
Languages : en
Pages : 711

Book Description
There has been substantial progress in understanding the contributions of the auditory forebrain to hearing, sound localization, communication, emotive behavior, and cognition. The Auditory Cortex covers the latest knowledge about the auditory forebrain, including the auditory cortex as well as the medial geniculate body in the thalamus. This book will cover all important aspects of the auditory forebrain organization and function, integrating the auditory thalamus and cortex into a smooth, coherent whole. Volume One covers basic auditory neuroscience. It complements The Auditory Cortex, Volume 2: Integrative Neuroscience, which takes a more applied/clinical perspective.