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Author: Dori Derdikman Publisher: Springer ISBN: 3709112923 Category : Medical Languages : en Pages : 567
Book Description
The discovery of new cell types, such as grid and time cells, in the hippocampus has been accompanied by major anatomical and theoretical insights in the recent years. This book provides comprehensive, up-to-date information about the hippocampal formation and especially the neural basis of episodic memory, spatial location (the formation of the cognitive map) and temporal representation. The first part of the book describes the information flow from pre-hippocampal areas into the hippocampus, the second part discusses the different types of hippocampal processing and finally, the third part depicts the influence that the hippocampal processing has on other brain structures that are perhaps more closely tied to explicit cognitive or behavioral output. This book is intended for neuroscientists, especially for those who are involved in research on the hippocampus, as well as for behavioral scientists and neurologists.
Author: Dori Derdikman Publisher: Springer ISBN: 3709112923 Category : Medical Languages : en Pages : 567
Book Description
The discovery of new cell types, such as grid and time cells, in the hippocampus has been accompanied by major anatomical and theoretical insights in the recent years. This book provides comprehensive, up-to-date information about the hippocampal formation and especially the neural basis of episodic memory, spatial location (the formation of the cognitive map) and temporal representation. The first part of the book describes the information flow from pre-hippocampal areas into the hippocampus, the second part discusses the different types of hippocampal processing and finally, the third part depicts the influence that the hippocampal processing has on other brain structures that are perhaps more closely tied to explicit cognitive or behavioral output. This book is intended for neuroscientists, especially for those who are involved in research on the hippocampus, as well as for behavioral scientists and neurologists.
Author: Sheri J.Y. Mizumori Publisher: Oxford University Press ISBN: 0198043457 Category : Medical Languages : en Pages : 431
Book Description
Data from neuropsychological and animal research suggest that the hippocampus plays a pivotal role in two relatively different areas: active navigation, as well as episodic learning and memory. Recent studies have attempted to bridge these disparate accounts of hippocampal function by emphasizing the role that hippocampal place cells may play in processing the spatial contextual information that defines situations in which learned behaviors occur. A number of established laboratories are currently offering complementary interpretations of place fields, and this book will present the first common platform for them. Bringing together research from behavioral, genetic, physiological, computational, and neural-systems perspectives will provide a thorough understanding of the extent to which studying place-field properties has informed our understanding of the neural mechanisms of hippocampus-dependent memory. Hippocampal Place Fields: Relevance to Learning and Memory will serve as a valuable reference for everyone interested in hippocampal function.
Author: Deborah E. Hannula Publisher: Springer ISBN: 3319504061 Category : Medical Languages : en Pages : 587
Book Description
The hippocampus has long been considered a critical substrate in the neurobiology, neuropsychology, and cognitive neuroscience of memory. Over the past few decades, a number of ground-breaking theoretical and methodological advances have radically enhanced our understanding of the structure and function of the hippocampus and revolutionized the neuroscientific study of memory. Cutting across disciplines and approaches, these advances offer novel insights into the molecular and cellular structure and physiology of the hippocampus, the role of hippocampus in the formation, (re)consolidation, enhancement, and retrieval of memory across time and development, and permit investigators to address questions about how the hippocampus interacts, functionally and anatomically, with other neural systems in service of memory. In addition, recent investigations also suggest that the mechanistic properties and functional processing features of the hippocampus permit broader contributions to cognition, beyond memory, to the domains of attention, decision-making, language, social cognition, and a variety of other capacities that are critical for flexible cognition and behavior. These advances have profound implications for the neurobiology and cognitive neuroscience of hippocampus dependent cognition and for the numerous psychiatric and neurological diseases and disorders for which hippocampal pathology is a hallmark such as Alzheimer’s disease and schizophrenia. The goal of this book is to bring together in a single source an integrated review of these advances providing state of the art treatment on the structure and function of the hippocampus. Contributors will examine the hippocampus from a variety of levels (from cells to systems) using a wide range of methods (from neurobiological approaches in non-human animals to neuroimaging and neuropsychological work in humans).
Author: György Buzsáki Publisher: Springer ISBN: 3319288024 Category : Medical Languages : en Pages : 181
Book Description
This book brings together leading investigators who represent various aspects of brain dynamics with the goal of presenting state-of-the-art current progress and address future developments. The individual chapters cover several fascinating facets of contemporary neuroscience from elementary computation of neurons, mesoscopic network oscillations, internally generated assembly sequences in the service of cognition, large-scale neuronal interactions within and across systems, the impact of sleep on cognition, memory, motor-sensory integration, spatial navigation, large-scale computation and consciousness. Each of these topics require appropriate levels of analyses with sufficiently high temporal and spatial resolution of neuronal activity in both local and global networks, supplemented by models and theories to explain how different levels of brain dynamics interact with each other and how the failure of such interactions results in neurologic and mental disease. While such complex questions cannot be answered exhaustively by a dozen or so chapters, this volume offers a nice synthesis of current thinking and work-in-progress on micro-, meso- and macro- dynamics of the brain.
Author: J. David Sweatt Publisher: Academic Press ISBN: 0080959199 Category : Psychology Languages : en Pages : 362
Book Description
This fully revised second edition provides the only unified synthesis of available information concerning the mechanisms of higher-order memory formation. It spans the range from learning theory, to human and animal behavioral learning models, to cellular physiology and biochemistry. It is unique in its incorporation of chapters on memory disorders, tying in these clinically important syndromes with the basic science of synaptic plasticity and memory mechanisms. It also covers cutting-edge approaches such as the use of genetically engineered animals in studies of memory and memory diseases. Written in an engaging and easily readable style and extensively illustrated with many new, full-color figures to help explain key concepts, this book demystifies the complexities of memory and deepens the reader’s understanding. More than 25% new content, particularly expanding the scope to include new findings in translational research. Unique in its depth of coverage of molecular and cellular mechanisms Extensive cross-referencing to Comprehensive Learning and Memory Discusses clinically relevant memory disorders in the context of modern molecular research and includes numerous practical examples
Author: Per Andersen Publisher: Oxford University Press ISBN: 9780195100273 Category : Medical Languages : en Pages : 892
Book Description
The hippocampus is one of a group of remarkable structures embedded within the brain's medial temporal lobe. Long known to be important for memory, it has been a prime focus of neuroscience research for many years. The Hippocampus Book promises to facilitate developments in the field in a major way by bringing together, for the first time, contributions by leading international scientists knowledgeable about hippocampal anatomy, physiology, and function. This authoritative volume offers the most comprehensive, up-to-date account of what the hippocampus does, how it does it, and what happens when things go wrong. At the same time, it illustrates how research focusing on this single brain structure has revealed principles of wider generality for the whole brain in relation to anatomical connectivity, synaptic plasticity, cognition and behavior, and computational algorithms. Well-organized in its presentation of both theory and experimental data, this peerless work vividly illustrates the astonishing progress that has been made in unraveling the workings of the brain. The Hippocampus Book is destined to take a central place on every neuroscientist's bookshelf.
Author: Ahmed Tarek Hussin Publisher: ISBN: Category : Languages : en Pages : 0
Book Description
Memory is one of the most important faculties of the mind. Memory keeps a record of our experiences which enriches our sense of self, enables us to make adaptive decisions in the present and informed plans for the future. Historically, memory research has focused on the hippocampal formation in the medial temporal lobes which is critical in the initial stages of memory formation. More recently, memory research expanded to include neocortical areas especially with regards to remote memory. An open question in neuroscience is what happens to memory representations in the brain with time. It remains unclear whether the contribution of the hippocampus to memory decreases with time in favour of the neocortex, or if both their contributions stay the same. In this dissertation, I use the non-human primate model to examine the neural mechanism underlying memory formation in the hippocampus, as well as the contribution of neocortical areas during remote memory. In the first study, I present findings that the neural mechanism underlying memory is heterogenous; varying by waking state and underlying spiking of different neuronal types. In the second study, I focus on two neocortical areas alongside the hippocampus and present findings that support a greater role for neocortical areas during remote memory. These findings support the idea that memory dependence shifts to areas outside the hippocampus with time.
Author: Yuichi Takeuchi Publisher: Frontiers Media SA ISBN: 2832512550 Category : Science Languages : en Pages : 115
Book Description
Oscillatory brain activities reflect and affect network activities in the brain. They support many physiological functions from motor control to cognition and emotion. Abnormal oscillatory brain activities are commonly observed in neurological and psychiatric disorders including epilepsy, Parkinson’s disease, Alzheimer’s disease, schizophrenia, anxiety/trauma-related disorders, major depressive disorders, addiction, etc. Therefore, these disorders can be considered as common oscillation defects “oscillopathies” despite having distinct behavioral manifestations. Recent advances in brain activity measurements and analyses have allowed us to study the pathological oscillations of each disorder as a possible biomarker of symptoms. Furthermore, novel brain stimulation technologies will enable time- and space-targeted interventions of the pathological oscillations of both neurological and psychiatric disorders as possible therapeutic targets for regulating their symptoms. This Research Topic focused on understanding and controlling pathological oscillations in the brain will provide a comprehensive overview of pathological oscillations in neurological and psychiatric disorders. This Research Topic will also examine correlations or causal relationships between pathological oscillations and the symptoms of disorders with a view to the possible use of oscillations as biomarkers or therapeutic targets. Good animal models that accurately reflect neurological and psychiatric symptoms of patients are necessary for providing the proof-of-concept toward future translational research. Large-scale recording and reliable decoding technologies are crucial for discovering the correlations between pathological oscillations and some symptoms, while time- and space-targeted intervention technologies are necessary for studying their causal relationships, Such data will eventually allow the development of neuroprosthesis devices for pathological oscillations. Revealing the mechanisms of physiological oscillations is also important for the direction of this topic.
Author: Per Andersen Publisher: Oxford University Press ISBN: 0195100271 Category : Medical Languages : en Pages : 853
Book Description
The hippocampus is one of a group of remarkable structures embedded within the brain's medial temporal lobe. Long known to be important for memory, it has been a prime focus of neuroscience research for many years. The Hippocampus Book promises to facilitate developments in the field in a major way by bringing together, for the first time, contributions by leading international scientists knowledgeable about hippocampal anatomy, physiology, and function. This authoritative volume offers the most comprehensive, up-to-date account of what the hippocampus does, how it does it, and what happens when things go wrong. At the same time, it illustrates how research focusing on this single brain structure has revealed principles of wider generality for the whole brain in relation to anatomical connectivity, synaptic plasticity, cognition and behavior, and computational algorithms. Well-organized in its presentation of both theory and experimental data, this peerless work vividly illustrates the astonishing progress that has been made in unraveling the workings of the brain. The Hippocampus Book is destined to take a central place on every neuroscientist's bookshelf.
Author: Dori Derdikman
Author: Dori Derdikman
Author: Sheri J.Y. Mizumori
Author: Deborah E. Hannula
Author: VOGT
Author: György Buzsáki
Author: J. David Sweatt
Author: Per Andersen
Author: Ahmed Tarek Hussin
Author: Yuichi Takeuchi
Author: Per Andersen