Smart Diagnostics for Neurodegenerative Disorders PDF Download

Author: Arpana Parihar
Publisher: Elsevier
ISBN: 0323955401
Category : Science
Languages : en
Pages : 379

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Book Description
Smart Diagnostics for Neurodegenerative Disorders: Neuro-sensors explores all available biosensor-based approaches and technologies as well as their use in the diagnosis, prognosis and therapeutic management of a variety of neurological disorders such as Alzheimer's, Parkinson's and epileptic disorders. The book also discusses contemporary and revolutionary biosensor platforms that are being used to produce a quantitative quick lab-on-a-chip point-of-care (POC) assay for several types of predictive and diagnostic biomarkers linked with neurodegenerative disorders. It offers a combinatorial strategy for learning recent advances and designing new biosensor-based technologies in the fields of medical science, engineering and biomedical technology. Early detection of neurological conditions has the potential to treat the disease and extend the life expectancy of patients. Recent improvements in biosensor-based approaches that target specific cell surface biomarkers can be used for early detection of neurodegenerative disease. Provides an in-depth understanding of biomarkers associated with neurodegenerative disease to build and create a variety of biosensors Presents biosensor-based strategies to create and construct enhanced platforms for quick diagnosis of biomarkers linked to a variety of neurological illnesses Discusses the current challenges and future trends in developing diagnostic devices for early detection of neurodegenerative disorders, presenting new avenues for more sensitive and selective point-of-care devices

Author: Megha Agrawal
Publisher: Frontiers Media SA
ISBN: 2889451941
Category :
Languages : en
Pages : 92

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Book Description
Neurodegeneration is characterized by the progressive loss of neural tissue that result in various neurodegeneration-initiated cerebral failures and complex diseases such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease. All these medical conditions are accompanied by the disruption of blood-brain barrier (BBB). The BBB is an interface, separating the brain from the circulatory system and protecting the central nervous system from potentially harmful chemicals while regulating transport of essential molecules and maintaining a stable environment. Owing to the inability of the neurons to regenerate on their own after neurodegeneration or severe damage to the neural tissue, neurodegenerative disorders do not have natural cures on their own. Neuroregeneration is a viable way to curb neurodegeneration. One of the current approaches is stem cell-based therapy that has been shown to be potentially helpful for the application of neuronal cell replacement for neuroregeneration. It is vital that the neurodegenerative disorder being detected at an early stage as it can provide a chance for treatment that may be helpful to prevent further progression of the fatal disease. Thus, research has focused on developing effective non-invasive diagnostic methods for early detection of these disorders. Molecular diagnostics can provide a powerful method to detect and diagnose various neurological disorders. Such diagnosis can enhance early detection, provide subsequent medical counsel based on medical pathway, as well as to gain better insight of neurogenesis and hopefully eventual cure of the neurodegenerative diseases. With research reports, reviews, mini-reviews and commentary, this research topic covers a wide range of areas in neurodegeneration research, including diagnosis and prognosis; regulating central nervous system; biomarkers and brain injury induced neurobehavioral outcomes among other timely reports on neurodegeneration.

Author: Anuradha Mishra
Publisher: Bentham Science Publishers
ISBN: 9815238760
Category : Medical
Languages : en
Pages : 243

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Book Description
Advances in Diagnostics and Immunotherapeutics for Neurodegenerative Diseases delves into the intricate mechanisms underlying neurodegenerative disorders and highlights cutting-edge diagnostic methods and innovative immunotherapeutic strategies. This comprehensive book addresses several key themes crucial to understanding and combating these debilitating conditions with an updated understanding of neurodegenerative disorders and a review of the latest advancements in diagnostic and treatment strategies. Key Themes Neuroinflammation: examines the complex molecular pathways involved in neuroinflammatory responses and their impact on disease dynamics. Gut-Brain Axis: A thorough discussion on the relationship between the gut microbiome and neurodegenerative processes is presented. Advanced Diagnostics: A state-of-the-art review of diagnostic techniques provides updates on advanced neuroimaging modalities, cerebrospinal fluid biomarker analysis, and genetic testing. Epigenetic Regulation of Microglia: Covers the emerging field of epigenetic modifications and their role in modulating microglial activation and function. Immunotherapeutics: Learn about the potential of monoclonal antibodies, immune modulators, and repurposed drug therapies in slowing disease progression and improving patient outcomes. This book serves as a valuable resource for researchers, clinicians, and students in the fields of molecular biology, neuroimmunology, and clinical neurology.

Author: Lars Lannfelt
Publisher:
ISBN: 9781493935604
Category : Biochemical markers
Languages : en
Pages : 289

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Book Description

Author: Nilanjan Dey
Publisher: CRC Press
ISBN: 1040105629
Category : Computers
Languages : en
Pages : 259

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Book Description
This book presents advanced research on smart health technologies, focusing on the innovative transformations in diagnosis and treatment planning using medical imaging and data analysed by data science techniques. It shows how smart health technologies leverage artificial intelligence (AI) and big data analytics to provide more accurate and efficient diagnosis and treatment planning. In search for innovative and novel methods and techniques for health technologies and medical data processing, the book • Discusses applications of Artificial Intelligence, Data Science, Machine Learning, Deep Learning, the Internet of Things, Big Data, Cloud Computing; • Includes use of electronic patient records in healthcare, analysis of big data in medical diagnosis, reliability, and challenges of EPR and EHR in smart healthcare; • Explores evolving techniques for smart healthcare, its application in medical imaging and prediction in the fields of treatment planning; • Provides recent studies in AI-driven healthcare technologies and medical imaging to outline insight into smart healthcare technologies; • Discusses the role of big data in smart healthcare, computing techniques for healthcare for medical diagnosis and treatment planning; • Encompasses the ethical and legal challenges of using smart healthcare and medical data. This book serves as a valuable reference for researchers working on smart health technologies. Researchers of medical imaging, artificial intelligence, and data science along with healthcare domain will find it a great resource as well.

Author: Zeshan, Furkh
Publisher: IGI Global
ISBN: 1668464357
Category : Medical
Languages : en
Pages : 299

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Book Description
Different healthcare technologies have been in use for decades. These technologies are continuously evolving and changing the way medicine will be practiced in the future. These technologies allow medical practice from anywhere, at any time, and from any device. These technologies are mainly concerned with the resources, devices, and methods required to optimize the acquisition, storage, retrieval, processing, and use of information in health. Recent Advancements in Smart Remote Patient Monitoring, Wearable Devices, and Diagnostics Systems provides relevant theoretical and practical frameworks, as well as the latest empirical research findings in the area. It provides insights and supports executives concerned with remote patient monitoring through wearable devices and diagnostics systems. Covering topics such as cloud computing, obesity monitoring systems, and photoacoustic imaging, this premier reference source is an essential resource for hospital administrators, medical technicians, healthcare professionals, medical students and educators, librarians, researchers, and academicians.

Author: Fernando Gomes
Publisher: Elsevier
ISBN: 0128235551
Category : Technology & Engineering
Languages : en
Pages : 474

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Book Description
Nanofabrication for Smart Nanosensor Applications addresses the design, manufacture and applications of a variety of nanomaterials for sensing applications. In particular, the book explores how nanofabrication techniques are used to create more efficient nanosensors, examines their major applications in biomedicine and environmental science, discusses the fundamentals of how nanosensors work, explores different nanofabrication techniques, and comments on toxicity and safety issues relating to the creation of nanosensors using certain nanomaterial classes. This book is an important resource for materials scientists and engineers who want to make materials selection decisions for the creation of new nansensor devices. Summarizes current research and applications of a variety of nanofabrication techniques for the creation of efficient sensing devices Provides readers with an understanding of surfaces and interfaces, a key challenge for those working on hybrid nanomaterials, carbon nanotubes, graphene, polymers and liquid crystal electro-optical imaging Discusses the variability and sight recognition of biopolymers, such as DNA molecules, which offer a wide range of opportunities for the self-organization of nanostructures into much more complex patterns

Author: Mrutyunjaya Panda
Publisher: CRC Press
ISBN: 1040085628
Category : Computers
Languages : en
Pages : 292

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Book Description
With the advent of computational intelligence-based approaches, such as bio-inspired techniques, and the availability of clinical data from various complex experiments, medical consultants, researchers, neurologists, and oncologists, there is huge scope for CI-based applications in medical oncology and neurological disorders. This book focuses on interdisciplinary research in this field, bringing together medical practitioners dealing with neurological disorders and medical oncology along with CI investigators. The book collects high-quality original contributions, containing the latest developments or applications of practical use and value, presenting interdisciplinary research and review articles in the field of intelligent systems for computational oncology and neurological disorders. Drawing from work across computer science, physics, mathematics, medical science, psychology, cognitive science, oncology, and neurobiology among others, it combines theoretical, applied, computational, experimental, and clinical research. It will be of great interest to any neurology or oncology researchers focused on computational approaches.

Author: Lilhore, Umesh Kumar
Publisher: IGI Global
ISBN:
Category : Medical
Languages : en
Pages : 477

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Book Description
Alzheimer's disease (AD) poses a significant global health challenge, with an estimated 50 million people affected worldwide and no known cure. Traditional methods of diagnosis and prediction often rely on subjective assessments. They are limited in detecting the disease early, leading to delayed intervention and poorer patient outcomes. Additionally, the complexity of AD, with its multifactorial etiology and diverse clinical manifestations, requires a multidisciplinary approach for effective management. AI-Driven Alzheimer's Disease Detection and Prediction offers a groundbreaking solution by leveraging advanced artificial intelligence (AI) techniques to enhance early diagnosis and prediction of AD. This edited book provides a comprehensive overview of state-of-the-art research, methodologies, and applications at the intersection of AI and AD detection. By bridging the gap between traditional diagnostic methods and cutting-edge technology, this book facilitates knowledge exchange, fosters interdisciplinary collaboration, and contributes to innovative solutions for AD management.

Author: Sathish-Kumar Kamaraj
Publisher: John Wiley & Sons
ISBN: 1394175205
Category : Science
Languages : en
Pages : 330

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Book Description
The book presents the fundamentals of nanomaterials, discusses the direct applications of nanomaterials to the biomedical sector, and explores the potential therapeutic applications of nanotheranostics. This book focuses on the fundamental features of various nanomaterials that are related to the development of biomedical technologies. These fundamental qualities are broken up into three parts: prevention, diagnostics, and therapeutics. When it comes to infectious diseases, prevention is of the utmost importance. Highly advanced nanomaterials including silver, titanium, graphene-based filters, and copper nanoparticles are used to fight infectious illnesses. Once the symptoms have been recognized in the patients, through the use of effective and straightforward nanodiagnostic techniques, the diseases can be accurately localized in either a qualitative or quantitative manner. Nanodiagnostics tools currently dominate the field of biomedical diagnostics because of their high degree of accuracy, low requirement for samples and reagents, user-friendliness, portability, and capacity to perform point-of-care (POC) applications. Nanomaterials are widely used in imaging due to many factors, including: their signal generation and amplification abilities; the ongoing development of reliant new imaging techniques, such as photoacoustic imaging and Raman imaging; their targeting potential, due to the possibility of functionalizing their surface with cancer-targeting moieties; their multimodality, since some nanomaterials can generate signals for more than one imaging technique; and their affordability. Modern therapeutics explores the various nanotechnological advances to cure the site-specific cancer treatment most prominently. The book explores the fundamentals of nanomaterials and discloses their direct application to the biomedical field. Finally, the book discusses future therapeutic applications of nanotheranostics. Audience The book will be read by scientists, researchers, and post-graduate students in the biomedical-related engineering field, nanoscience and nanotechnology, materials science, and bionanotechnology.