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Author: Makoto Oba Publisher: John Wiley & Sons ISBN: 3527836004 Category : Science Languages : en Pages : 421
Book Description
Cell-Penetrating Peptides The definitive reference on the rational design of cell-penetrating peptides enables readers to develop tailor-made peptides for their specific needs. In recent years, cell-penetrating peptides (CPPs) have become valuable tools for the cellular delivery of proteins, nucleic acids, and drugs. These small peptide sequences can be artificially designed and synthesized with custom-made characteristics to mediate the efficient and non-toxic transport of biomolecules, drugs, or nanoparticles into the cell. Cell-Penetrating Peptides: Design, Development, and Applications provides an up-to-date account of the development and use of CPPs for delivering membrane-impermeable bioactive molecules into cells. Bringing together contributions from leading researchers from around the world, this comprehensive volume describes the characteristics and mechanisms of CPPs as well as their application in both medicine, biotechnology and agriculture. Covers rational design and development of cell-penetrating peptides for use in cellular delivery of small molecule drugs, proteins, nucleic acids, and nanoparticles Presents the chemical and biological characteristics of CPP action in vitro and in vivo Describes the structure and design principles of both synthetic and naturally occurring CPPs Discusses key medical applications of CPPs such as oral delivery, intranasal delivery, and clinical trials Cell-Penetrating Peptides: Design, Development, and Applications is an essential resource for biochemists, medicinal chemists, molecular biologists, biotechnologists, and researchers studying CPPs in both academia and industry.
Author: Makoto Oba Publisher: John Wiley & Sons ISBN: 3527836004 Category : Science Languages : en Pages : 421
Book Description
Cell-Penetrating Peptides The definitive reference on the rational design of cell-penetrating peptides enables readers to develop tailor-made peptides for their specific needs. In recent years, cell-penetrating peptides (CPPs) have become valuable tools for the cellular delivery of proteins, nucleic acids, and drugs. These small peptide sequences can be artificially designed and synthesized with custom-made characteristics to mediate the efficient and non-toxic transport of biomolecules, drugs, or nanoparticles into the cell. Cell-Penetrating Peptides: Design, Development, and Applications provides an up-to-date account of the development and use of CPPs for delivering membrane-impermeable bioactive molecules into cells. Bringing together contributions from leading researchers from around the world, this comprehensive volume describes the characteristics and mechanisms of CPPs as well as their application in both medicine, biotechnology and agriculture. Covers rational design and development of cell-penetrating peptides for use in cellular delivery of small molecule drugs, proteins, nucleic acids, and nanoparticles Presents the chemical and biological characteristics of CPP action in vitro and in vivo Describes the structure and design principles of both synthetic and naturally occurring CPPs Discusses key medical applications of CPPs such as oral delivery, intranasal delivery, and clinical trials Cell-Penetrating Peptides: Design, Development, and Applications is an essential resource for biochemists, medicinal chemists, molecular biologists, biotechnologists, and researchers studying CPPs in both academia and industry.
Author: Allen James Fromherz Publisher: Univ of California Press ISBN: 0520398564 Category : History Languages : en Pages : 335
Book Description
This sweeping history reorients our understanding of the Middle East, placing the Gulf at the heart of globalized trade and cross-cultural encounters. World history began in the Persian Gulf. The ancient port cities that dotted its coastlines created the first global seaboard, a place from where faiths and cultures from around the world set sail and made contact. More than a history, The Center of the World shows us that contradictions that define our modern age have always been present. For over four thousand years, the Gulf—sometimes called the Persian Gulf, sometimes the Arabian Gulf—has been a global crossroads while managing to avoid control by the world’s greatest empires. In its history, we see a world of rapid change, fluctuating centers of trade, a dependency on uncertain global markets, and intense cross-cultural encounters that hold a mirror to the contemporary world. Focusing each chapter on a different port around the Gulf, The Center of the World shows how the people of the Gulf adapted to larger changes in world history, creating a system of free trade, merchant rule, and commerce that continues to define the region today.
Author: Sir Arnold Talbot Wilson Publisher: ISBN: Category : Middle East Languages : en Pages : 394
Book Description
Sir Arnold Talbot Wilson (1884-1940) was a British colonial administrator, soldier, and politician. He graduated from the Royal Military Academy Sandhurst in 1903 and served as an officer in the British Army in India. He was transferred to the Indian Political Department and subsequently sent to the Persian Gulf. Wilson was the British civil commissioner in Baghdad in 1918-20. Although he was credited with improving the country's administration, he was criticized for his violent repression of the 1920 Iraqi revolt against the British. At the 1919 Paris Peace Conference that followed World War I, he successfully recommended changing the Greek name "Mesopotamia" to the Arabic "Iraq." However, the British government ultimately rejected his view that Iraq should not be granted independence, and he was removed from his position. Wilson later became a member of Parliament. With the outbreak of World War II, he joined the Royal Air Force Volunteer Reserve. He served as a pilot officer and was killed in action in northern France. The Persian Gulf. An Historical Sketch from the Earliest Times to the Beginning of the Twentieth Century is a concise history of the region. Wilson begins with the writings of Greek, Roman, and Muslim geographers, followed by chapters on the arrival of European powers, beginning with the Portuguese, the British, and the Dutch. A later chapter discusses the growth of the British influence, starting in the 18th century. Other topics covered in the book are piracy, the slave trade, and the growth of Arab principalities.
Author: Robert Hillenbrand Publisher: Columbia University Press ISBN: 9780231101325 Category : Architecture Languages : en Pages : 716
Book Description
This is the definitive survey of Islamic architecture. Working from a social, rather than a technical perspective, Hillenbrand shows how the buildings fulfilled their intended functions within the community. Lavishly illustrated.
Author: Cahier d’Archipel 42 Publisher: Kepustakaan Populer Gramedia ISBN: 2910513696 Category : History Languages : en Pages : 522
Book Description
For the last century and a half, the name of Padang Lawas, in the present province of North Sumatra, Indonesia, has been associated with a number of isolated Hindu- Buddhist remains located in the middle of the island. These remains are all the more remarkable because they form the largest Indianized archaeological complex yet to be seen in the northern half of Sumatra. This book is the latest contribution to the accumulation of knowledge on the ancient history of Padang Lawas. The ?fteen studies brought together here present the main results of the archaeological research programme conducted from 2006 until 2010 by the Ecole francaise d’Extréme-Orient in cooperation with the Indonesian National Centre for Archaeological Research. This programme was focused on one of the sites known in this region, namely Si Pamutung, presently located near the con?uence of the Bammun and Batang Pane Rivers. These contributions are devoted ?rstly to the directly visible features of Si Pamutung, namely its environmental setting and its Hindu-Buddhist remains made of brick and stone.
Author: L. Potter Publisher: Springer ISBN: 0230618456 Category : History Languages : en Pages : 323
Book Description
Exploring the history of the Persian Gulf from ancient times until the present day, leading authorities treat the internal history of the region and describe the role outsiders have played there. The book focuses on the unity and identity of Gulf society and how the Gulf historically has been part of a cosmopolitan Indian Ocean world.
Author: Marcus Milwright Publisher: Edinburgh University Press ISBN: 0748629955 Category : History Languages : en Pages : 272
Book Description
Traces archaeology's contribution to Islamic culture from its earliest manifestations to the present This introduction to the archaeology of the Islamic world traces the history of the discipline from its earliest manifestations through to the present and evaluates the contribution made by archaeology to the understanding of key aspects of Islamic culture. The author argues that it is essential for the results of archaeological research to be more fully integrated into the wider historical study of the Islamic world. His organisation of the book into broad themes allows a focus on issues that are relevant across different regions and periods, and the broad geographical scope reflects the main focus of archaeological work in the Islamic world to the present day. Key Features Includes short case studies to allow the reader to examine the ways in which archaeologists collect and interpret material in specific contexts Considers archaeological work conducted in the area stretching from Afghanistan and the Central Asian republics in the east to Spain in the west Draws comparisons with Islamic regions of sub-Saharan Africa and the Indian subcontinent Includes a Glossary of archaeological terminology and Arabic, Persian and Turkish terms
Author: St John Simpson Publisher: Archaeopress Publishing Ltd ISBN: 1803274190 Category : History Languages : en Pages : 538
Book Description
This collection of essays offers an examination of the Sasanian empire based almost entirely on archaeological and scientific research, much presented here for the first time. The book is divided into three parts examining Sasanian sites, settlements and landscapes; their complex agricultural resources; and their crafts and industries.
Author: George F. Hourani Publisher: Princeton University Press ISBN: 9780691000329 Category : Business & Economics Languages : en Pages : 220
Book Description
In this classic work George Hourani deals with the history of the sea trade of the Arabs in the Indian Ocean from its obscure origins many centuries before Christ to the time of its full extension to China and East Africa in the ninth and tenth centuries. The book comprises a brief but masterly historical account that has never been superseded. The author gives attention not only to geography, meteorology, and the details of travel, but also to the ships themselves, including a discussion of the origin of stitched planking and of the lateen fore-and-aft sails. Piracy in the Indian Ocean, day-to-day life at sea, the establishment of ancient lighthouses and the production of early maritime guides, handbooks, and port directories are all described in fascinating detail. Arab Seafaring will appeal to anyone interested in Arab life or the history of navigation. For this expanded edition, John Carswell has added a new introduction, a bibliography, and notes that add material from recent archaeological research.
Author: Makoto Oba
Author: Makoto Oba
Author: Allen James Fromherz
Author: David Whitehouse
Author: Sir Arnold Talbot Wilson
Author: Robert Hillenbrand
Author: Cahier d’Archipel 42
Author: L. Potter
Author: Marcus Milwright
Author: St John Simpson
Author: George F. Hourani