Author: Publisher:
ISBN:
Category : Carbon dioxide
Languages : en
Pages : 215
Book Description
Single and Multiple Inert Gas Washout
Author: Single and Multiple Inert Gas Washout
Author: The Multiple Inert Gas Elimination Technique (MIGET)
Author: Susan R. HopkinsPublisher: Springer
ISBN: 1493974416
Category : Medical
Languages : en
Pages : 338
Book Description
The Multiple Inert Gas Elimination Technique (MIGET) is a complex methodology involving specialized gas chromatography and sophisticated mathematics developed in the early 1970’s. Essentially, nobody possesses knowledge of all its elements except for its original developers, and while some practical and theoretical aspects have been published over the years, none have included the level of detail that would be necessary for a potential user to adopt and understand the technique easily. This book is unique in providing a highly detailed, comprehensive technical description of the theory and practice underlying the MIGET to help potential users set up the method and solve problems they may encounter. But it is much more than a reference manual – it is a substantial physiological and mathematical treatise in its own right. It also has a wide applicability – there is extensive discussion of the common biological problem of quantitative inference. The authors took measured whole-lung gas exchange variables, and used mathematical procedures to infer the distribution of ventilation and blood flow from this data. In so doing, they developed novel approaches to answer the question: What are the limits to what can be concluded when inferring the inner workings from the “black box” behavior of a system? The book details the approaches developed, which can be generalized to other similar distributed functions within tissues and organs. They involve engineering approaches such as linear and quadratic programming, and uniquely use mathematical tools with biological constraints to obtain as much information as possible about a “black box” system. Lastly, the book summarizes the hundreds of research papers published by a number of groups over the decades in a way never before attempted in order to marshal the world’s literature on the topic and to provide in one place the wealth of important discoveries, both physiological a nd clinical, enabled by the technique.
Multiple Breath Inert Gas Washout
Author: Simon J. TavenerPublisher:
ISBN:
Category : Lungs
Languages : en
Pages : 184
Book Description
The Multiple Inert Gas Elimination Technique (MIGET)
Author: Susan R. HopkinsPublisher: Springer
ISBN: 9781493984879
Category : Medical
Languages : en
Pages : 329
Book Description
The Multiple Inert Gas Elimination Technique (MIGET) is a complex methodology involving specialized gas chromatography and sophisticated mathematics developed in the early 1970’s. Essentially, nobody possesses knowledge of all its elements except for its original developers, and while some practical and theoretical aspects have been published over the years, none have included the level of detail that would be necessary for a potential user to adopt and understand the technique easily. This book is unique in providing a highly detailed, comprehensive technical description of the theory and practice underlying the MIGET to help potential users set up the method and solve problems they may encounter. But it is much more than a reference manual – it is a substantial physiological and mathematical treatise in its own right. It also has a wide applicability – there is extensive discussion of the common biological problem of quantitative inference. The authors took measured whole-lung gas exchange variables, and used mathematical procedures to infer the distribution of ventilation and blood flow from this data. In so doing, they developed novel approaches to answer the question: What are the limits to what can be concluded when inferring the inner workings from the “black box” behavior of a system? The book details the approaches developed, which can be generalized to other similar distributed functions within tissues and organs. They involve engineering approaches such as linear and quadratic programming, and uniquely use mathematical tools with biological constraints to obtain as much information as possible about a “black box” system. Lastly, the book summarizes the hundreds of research papers published by a number of groups over the decades in a way never before attempted in order to marshal the world’s literature on the topic and to provide in one place the wealth of important discoveries, both physiological a nd clinical, enabled by the technique.
Gas Mixing and Distribution in the Lung
Author: Ludwig A. EngelPublisher: CRC Press
ISBN: 9780824772840
Category : Medical
Languages : en
Pages : 432
Book Description
This impressive volume presents a state-of-the-art synthesis of all aspects of gas mixing and ventilation distribution in the lung, blending current theoretical understanding with the most recent experimental findings for complete coverage unavailable in any other single source. Written by an international panel of renowned physiologists, physicists, engineers, and physicians, Gas Mixing and Distribution in the Lung examines basic principles of molecular diffusion, plus lung anatomy and how it influences gas mixing and distribution ... mathematical and computer models being developed to better understand gas mixing in the lung -- an area of rapid, exciting advances ... dispersion of gases in conducting airways, as well as mechanisms for axial dispersion that sustain alveolar ventilation and gas exchange at high-frequency ventilation ... regional ventilation distribution -- where improvements in the use of radioactive gas isotopes and imaging facilities are providing new findings ... topics in comparative physiology, respiratory disease states, and more. Gathering the widely scattered, multidisciplinary knowledge in one well-illustrated and fully referenced resource, this comprehensive volume provides the authoritative insight into the subject required by pulmonary physiologists, pneumologists, anesthesiologists, biomedical engineers, biophysicists, physiotherapists, nuclear medicine specialists, inhalation therapists, and medical students. Also, the book is an excellent reference for graduate-level courses in Respiratory Physiology or Comparative Physiology. Book jacket.
Basic Physiology for Anaesthetists
Author: David ChambersPublisher: Cambridge University Press
ISBN: 1108463991
Category : Medical
Languages : en
Pages : 469
Book Description
Easily understood, up-to-date and clinically relevant, this book provides junior anaesthetists with an essential physiology resource.
Infant Respiratory Function Testing
Author: Janet StocksPublisher: John Wiley & Sons
ISBN: 9780471076827
Category : Medical
Languages : en
Pages : 628
Book Description
This book is a step-by-step guide to procedures and analysis of infant lung function testing. Each test description is preceded by a brief resume of the theoretical background. A troubleshooting section compiles the problems most frequently encountered during measurement and analysis. This book will provide those training in pediatric pulmonary with a sound grasp of the fundamental principles and practical issues involved in measuring infant lung function.
Pulmonary Gas Exchange
Author: G. Kim PriskPublisher: Biota Publishing
ISBN: 1615044515
Category : Science
Languages : en
Pages : 88
Book Description
The lung receives the entire cardiac output from the right heart and must load oxygen onto and unload carbon dioxide from perfusing blood in the correct amounts to meet the metabolic needs of the body. It does so through the process of passive diffusion. Effective diffusion is accomplished by intricate parallel structures of airways and blood vessels designed to bring ventilation and perfusion together in an appropriate ratio in the same place and at the same time. Gas exchange is determined by the ventilation-perfusion ratio in each of the gas exchange units of the lung. In the normal lung ventilation and perfusion are well matched, and the ventilation-perfusion ratio is remarkably uniform among lung units, such that the partial pressure of oxygen in the blood leaving the pulmonary capillaries is less than 10 Torr lower than that in the alveolar space. In disease, the disruption to ventilation-perfusion matching and to diffusional transport may result in inefficient gas exchange and arterial hypoxemia. This volume covers the basics of pulmonary gas exchange, providing a central understanding of the processes involved, the interactions between the components upon which gas exchange depends, and basic equations of the process.
Air Pollution, the Automobile, and Public Health
Author: Sponsored by The Health Effects InstitutePublisher: National Academies Press
ISBN: 0309037263
Category : Science
Languages : en
Pages : 703
Book Description
"The combination of scientific and institutional integrity represented by this book is unusual. It should be a model for future endeavors to help quantify environmental risk as a basis for good decisionmaking." â€"William D. Ruckelshaus, from the foreword. This volume, prepared under the auspices of the Health Effects Institute, an independent research organization created and funded jointly by the Environmental Protection Agency and the automobile industry, brings together experts on atmospheric exposure and on the biological effects of toxic substances to examine what is knownâ€"and not knownâ€"about the human health risks of automotive emissions.