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Computational Genomics with R

Computational Genomics with R PDF Author: Altuna Akalin
Publisher: CRC Press
ISBN: 1498781861
Category : Mathematics
Languages : en
Pages : 463

Book Description
Computational Genomics with R provides a starting point for beginners in genomic data analysis and also guides more advanced practitioners to sophisticated data analysis techniques in genomics. The book covers topics from R programming, to machine learning and statistics, to the latest genomic data analysis techniques. The text provides accessible information and explanations, always with the genomics context in the background. This also contains practical and well-documented examples in R so readers can analyze their data by simply reusing the code presented. As the field of computational genomics is interdisciplinary, it requires different starting points for people with different backgrounds. For example, a biologist might skip sections on basic genome biology and start with R programming, whereas a computer scientist might want to start with genome biology. After reading: You will have the basics of R and be able to dive right into specialized uses of R for computational genomics such as using Bioconductor packages. You will be familiar with statistics, supervised and unsupervised learning techniques that are important in data modeling, and exploratory analysis of high-dimensional data. You will understand genomic intervals and operations on them that are used for tasks such as aligned read counting and genomic feature annotation. You will know the basics of processing and quality checking high-throughput sequencing data. You will be able to do sequence analysis, such as calculating GC content for parts of a genome or finding transcription factor binding sites. You will know about visualization techniques used in genomics, such as heatmaps, meta-gene plots, and genomic track visualization. You will be familiar with analysis of different high-throughput sequencing data sets, such as RNA-seq, ChIP-seq, and BS-seq. You will know basic techniques for integrating and interpreting multi-omics datasets. Altuna Akalin is a group leader and head of the Bioinformatics and Omics Data Science Platform at the Berlin Institute of Medical Systems Biology, Max Delbrück Center, Berlin. He has been developing computational methods for analyzing and integrating large-scale genomics data sets since 2002. He has published an extensive body of work in this area. The framework for this book grew out of the yearly computational genomics courses he has been organizing and teaching since 2015.

Computational Genomics with R

Computational Genomics with R PDF Author: Altuna Akalin
Publisher: CRC Press
ISBN: 1498781861
Category : Mathematics
Languages : en
Pages : 463

Book Description
Computational Genomics with R provides a starting point for beginners in genomic data analysis and also guides more advanced practitioners to sophisticated data analysis techniques in genomics. The book covers topics from R programming, to machine learning and statistics, to the latest genomic data analysis techniques. The text provides accessible information and explanations, always with the genomics context in the background. This also contains practical and well-documented examples in R so readers can analyze their data by simply reusing the code presented. As the field of computational genomics is interdisciplinary, it requires different starting points for people with different backgrounds. For example, a biologist might skip sections on basic genome biology and start with R programming, whereas a computer scientist might want to start with genome biology. After reading: You will have the basics of R and be able to dive right into specialized uses of R for computational genomics such as using Bioconductor packages. You will be familiar with statistics, supervised and unsupervised learning techniques that are important in data modeling, and exploratory analysis of high-dimensional data. You will understand genomic intervals and operations on them that are used for tasks such as aligned read counting and genomic feature annotation. You will know the basics of processing and quality checking high-throughput sequencing data. You will be able to do sequence analysis, such as calculating GC content for parts of a genome or finding transcription factor binding sites. You will know about visualization techniques used in genomics, such as heatmaps, meta-gene plots, and genomic track visualization. You will be familiar with analysis of different high-throughput sequencing data sets, such as RNA-seq, ChIP-seq, and BS-seq. You will know basic techniques for integrating and interpreting multi-omics datasets. Altuna Akalin is a group leader and head of the Bioinformatics and Omics Data Science Platform at the Berlin Institute of Medical Systems Biology, Max Delbrück Center, Berlin. He has been developing computational methods for analyzing and integrating large-scale genomics data sets since 2002. He has published an extensive body of work in this area. The framework for this book grew out of the yearly computational genomics courses he has been organizing and teaching since 2015.

Similarity-Based Clustering

Similarity-Based Clustering PDF Author: Thomas Villmann
Publisher: Springer Science & Business Media
ISBN: 3642018041
Category : Computers
Languages : en
Pages : 211

Book Description
This book is the outcome of the Dagstuhl Seminar on "Similarity-Based Clustering" held at Dagstuhl Castle, Germany, in Spring 2007. In three chapters, the three fundamental aspects of a theoretical background, the representation of data and their connection to algorithms, and particular challenging applications are considered. Topics discussed concern a theoretical investigation and foundation of prototype based learning algorithms, the development and extension of models to directions such as general data structures and the application for the domain of medicine and biology. Similarity based methods find widespread applications in diverse application domains, including biomedical problems, but also in remote sensing, geoscience or other technical domains. The presentations give a good overview about important research results in similarity-based learning, whereby the character of overview articles with references to correlated research articles makes the contributions particularly suited for a first reading concerning these topics.

Large-Scale Group Decision-Making

Large-Scale Group Decision-Making PDF Author: Su-Min Yu
Publisher: Springer Nature
ISBN: 9811678898
Category : Business & Economics
Languages : en
Pages : 195

Book Description
This book explores clustering operations in the context of social networks and consensus-reaching paths that take into account non-cooperative behaviors. This book focuses on the two key issues in large-scale group decision-making: clustering and consensus building. Clustering aims to reduce the dimension of a large group. Consensus reaching requires that the divergent individual opinions of the decision makers converge to the group opinion. This book emphasizes the similarity of opinions and social relationships as important measurement attributes of clustering, which makes it different from traditional clustering methods with single attribute to divide the original large group without requiring a combination of the above two attributes. The proposed consensus models focus on the treatment of non-cooperative behaviors in the consensus-reaching process and explores the influence of trust loss on the consensus-reaching process.The logic behind is as follows: firstly, a clustering algorithm is adopted to reduce the dimension of decision-makers, and then, based on the clusters’ opinions obtained, a consensus-reaching process is carried out to obtain a decision result acceptable to the majority of decision-makers. Graduates and researchers in the fields of management science, computer science, information management, engineering technology, etc., who are interested in large-scale group decision-making and consensus building are potential audience of this book. It helps readers to have a deeper and more comprehensive understanding of clustering analysis and consensus building in large-scale group decision-making.

Machine Learning and Data Mining in Pattern Recognition

Machine Learning and Data Mining in Pattern Recognition PDF Author: Petra Perner
Publisher: Springer Science & Business Media
ISBN: 3540405046
Category : Computers
Languages : en
Pages : 452

Book Description
TheInternationalConferenceonMachineLearningandDataMining(MLDM)is the third meeting in a series of biennial events, which started in 1999, organized by the Institute of Computer Vision and Applied Computer Sciences (IBaI) in Leipzig. MLDM began as a workshop and is now a conference, and has brought the topic of machine learning and data mining to the attention of the research community. Seventy-?ve papers were submitted to the conference this year. The program committeeworkedhardtoselectthemostprogressiveresearchinafairandc- petent review process which led to the acceptance of 33 papers for presentation at the conference. The 33 papers in these proceedings cover a wide variety of topics related to machine learning and data mining. The two invited talks deal with learning in case-based reasoning and with mining for structural data. The contributed papers can be grouped into nine areas: support vector machines; pattern dis- very; decision trees; clustering; classi?cation and retrieval; case-based reasoning; Bayesian models and methods; association rules; and applications. We would like to express our appreciation to the reviewers for their precise andhighlyprofessionalwork.WearegratefultotheGermanScienceFoundation for its support of the Eastern European researchers. We appreciate the help and understanding of the editorial sta? at Springer Verlag, and in particular Alfred Hofmann,whosupportedthepublicationoftheseproceedingsintheLNAIseries. Last, but not least, we wish to thank all the speakers and participants who contributed to the success of the conference.

Grouping Multidimensional Data

Grouping Multidimensional Data PDF Author: Jacob Kogan
Publisher: Taylor & Francis
ISBN: 9783540283485
Category : Computers
Languages : en
Pages : 296

Book Description
Publisher description

Data Clustering: Theory, Algorithms, and Applications, Second Edition

Data Clustering: Theory, Algorithms, and Applications, Second Edition PDF Author: Guojun Gan
Publisher: SIAM
ISBN: 1611976332
Category : Mathematics
Languages : en
Pages : 430

Book Description
Data clustering, also known as cluster analysis, is an unsupervised process that divides a set of objects into homogeneous groups. Since the publication of the first edition of this monograph in 2007, development in the area has exploded, especially in clustering algorithms for big data and open-source software for cluster analysis. This second edition reflects these new developments, covers the basics of data clustering, includes a list of popular clustering algorithms, and provides program code that helps users implement clustering algorithms. Data Clustering: Theory, Algorithms and Applications, Second Edition will be of interest to researchers, practitioners, and data scientists as well as undergraduate and graduate students.

Collaborative Filtering Using Data Mining and Analysis

Collaborative Filtering Using Data Mining and Analysis PDF Author: Bhatnagar, Vishal
Publisher: IGI Global
ISBN: 1522504907
Category : Computers
Languages : en
Pages : 336

Book Description
Internet usage has become a normal and essential aspect of everyday life. Due to the immense amount of information available on the web, it has become obligatory to find ways to sift through and categorize the overload of data while removing redundant material. Collaborative Filtering Using Data Mining and Analysis evaluates the latest patterns and trending topics in the utilization of data mining tools and filtering practices. Featuring emergent research and optimization techniques in the areas of opinion mining, text mining, and sentiment analysis, as well as their various applications, this book is an essential reference source for researchers and engineers interested in collaborative filtering.

Advanced Machine Learning Technologies and Applications

Advanced Machine Learning Technologies and Applications PDF Author: Aboul Ella Hassanien
Publisher: Springer
ISBN: 3642353266
Category : Computers
Languages : en
Pages : 606

Book Description
This book constitutes the refereed proceedings of the First International Conference on Advanced Machine Learning Technologies and Applications, AMLTA 2012, held in Cairo, Egypt, in December 2012. The 58 full papers presented were carefully reviewed and selected from 99 intial submissions. The papers are organized in topical sections on rough sets and applications, machine learning in pattern recognition and image processing, machine learning in multimedia computing, bioinformatics and cheminformatics, data classification and clustering, cloud computing and recommender systems.

Advances in Neural Information Processing Systems

Advances in Neural Information Processing Systems PDF Author: Thomas G. Dietterich
Publisher: MIT Press
ISBN: 9780262042086
Category : Computers
Languages : en
Pages : 832

Book Description
The proceedings of the 2001 Neural Information Processing Systems (NIPS) Conference. The annual conference on Neural Information Processing Systems (NIPS) is the flagship conference on neural computation. The conference is interdisciplinary, with contributions in algorithms, learning theory, cognitive science, neuroscience, vision, speech and signal processing, reinforcement learning and control, implementations, and diverse applications. Only about 30 percent of the papers submitted are accepted for presentation at NIPS, so the quality is exceptionally high. These proceedings contain all of the papers that were presented at the 2001 conference.

Time Series Clustering and Classification

Time Series Clustering and Classification PDF Author: Elizabeth Ann Maharaj
Publisher: CRC Press
ISBN: 0429603304
Category : Mathematics
Languages : en
Pages : 213

Book Description
The beginning of the age of artificial intelligence and machine learning has created new challenges and opportunities for data analysts, statisticians, mathematicians, econometricians, computer scientists and many others. At the root of these techniques are algorithms and methods for clustering and classifying different types of large datasets, including time series data. Time Series Clustering and Classification includes relevant developments on observation-based, feature-based and model-based traditional and fuzzy clustering methods, feature-based and model-based classification methods, and machine learning methods. It presents a broad and self-contained overview of techniques for both researchers and students. Features Provides an overview of the methods and applications of pattern recognition of time series Covers a wide range of techniques, including unsupervised and supervised approaches Includes a range of real examples from medicine, finance, environmental science, and more R and MATLAB code, and relevant data sets are available on a supplementary website