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Silica and Silica Induced Lung Diseases

Silica and Silica Induced Lung Diseases PDF Author: Vincent Castranova
Publisher: CRC-Press
ISBN: 9780849347092
Category : Medical
Languages : en
Pages : 432

Book Description
This book represents a comprehensive review of current concepts concerning the development, progression, and treatment of silica-induced lung diseases. The text begins with a complete review of the historical evolution of our understanding of silicosis and a discussion of the clinical and pathological features of this disease. It presents critical questions that must be resolved and then details state-of-the-art experiments that address these problems. The book presents an extensive discussion of new technologies that have increased our understanding of the relationship of surface properties of particulates to their cytotoxicity and pathogenicity. It also presents data that explain the intracellular and intercellular mechanisms involved in the pulmonary response to silica exposure.

Silica and Silica Induced Lung Diseases

Silica and Silica Induced Lung Diseases PDF Author: Vincent Castranova
Publisher: CRC-Press
ISBN: 9780849347092
Category : Medical
Languages : en
Pages : 432

Book Description
This book represents a comprehensive review of current concepts concerning the development, progression, and treatment of silica-induced lung diseases. The text begins with a complete review of the historical evolution of our understanding of silicosis and a discussion of the clinical and pathological features of this disease. It presents critical questions that must be resolved and then details state-of-the-art experiments that address these problems. The book presents an extensive discussion of new technologies that have increased our understanding of the relationship of surface properties of particulates to their cytotoxicity and pathogenicity. It also presents data that explain the intracellular and intercellular mechanisms involved in the pulmonary response to silica exposure.

Pathology of the Lungs E-Book

Pathology of the Lungs E-Book PDF Author: Bryan Corrin
Publisher: Elsevier Health Sciences
ISBN: 0702046221
Category : Medical
Languages : en
Pages : 785

Book Description
With an emphasis on practical diagnostic problem solving, Pathology of the Lungs, 3rd Edition provides the pulmonary pathologist and the general surgical pathologist with an accessible, comprehensive guide to the recognition and interpretation of common and rare neoplastic and non-neoplastic lung conditions. The text is written by two authors and covers all topics in a consistent manner without the redundancies or lapses that are common in multi-authored texts. The text is lavishly illustrated with the highest quality illustrations which accurately depict the histologic, immunohistochemical and cytologic findings under consideration and it is supplemented throughout with practical tips and advice from two internationally respected experts. The user-friendly design and format allows rapid access to essential information and the incorporation throughout of relevant clinical and radiographic information makes it a complete diagnostic resource inside the reporting room. Approximately 1,000 high quality full color illustrations.Provides the user with a complete visual guide to each specimen and assists in the recognition and diagnosis of any slide looked at under the microscope. Comprehensive coverage of both common and rare lung diseases and disorders. One stop consultation resource for the reporting room or study, no need to go further to get questions answered. Clinical background and ancillary radiographs incorporated throughout.Provides the user with all of the necessary diagnostic tools to make a complete and accurate pathologic report. Practical advice and tips from two of the world’s recognized experts. Provides the trainee and general surgical pathologist with time saving diagnostic clues when dealing with difficult specimens. Consistent and uniform approach incorporated for each disease and disorder (Etiology, pathogenesis, clinical features, pathologic features, differential diagnosis) User-friendly format enables quick and easy navigation to the key information required. Extensive use of summary tables, charts and graphs throughout the text. Helps simplify and clarify complex concepts and facilitates “at a glance comparisons between entities. Extensive reference list highlights landmark articles as well as including most up-to-date citations. Directs the trainee and practitioner to the most recent and authoritative sources for further reading and investigation

Crystalline Silica, Quartz

Crystalline Silica, Quartz PDF Author: F. Rice
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 62

Book Description
A concise assessment of the adverse effects on human health caused by exposure to quartz the most common form of crystalline silica. Quartz is a frequently occurring solid component of most natural mineral dusts. Human exposure occurs most often during occupational activities involving movement of earth disturbance of silica-containing products such as masonry and concrete or use or manufacture of silica-containing products. As respirable quartz dust particles can be inhaled and deposited in the lung the report gives particular attention to evidence of an increased risk of lung cancer in occupationally exposed workers. Most studies in laboratory animals have concentrated on adverse effects associated with long-term inhalation of particles. Effects observed include cellular proliferation nodule formation suppressed immune function and alveolar proteinosis. While exposure clearly induces pulmonary tumours in one species other species show less or no malignant tumour response. The evaluation of risks to human health draws on a large number of epidemiological studies of workers exposed to respirable quartz dust. Occupational exposure has been linked to an increased incidence of silicosis ung cancer and pulmonary tuberculosis. Studies have also documented statistically significant increases in cases of bronchitis emphysema chronic obstructive pulmonary disease autoimmune-related diseases including scleroderma rheumatoid arthritis and systemic lupus erythematosus and renal disease. In reviewing these findings the report underscores several uncertainties inherent to the study of respiratory diseases in occupational populations that complicate the assessment of risks associated with exposure to quartz dust. The need for improved methods of exposure assessment and data analysis is stressed.

Hamilton and Hardy's Industrial Toxicology

Hamilton and Hardy's Industrial Toxicology PDF Author: Raymond D. Harbison
Publisher: John Wiley & Sons
ISBN: 0470929731
Category : Science
Languages : en
Pages : 1364

Book Description
Providing a concise, yet comprehensive, reference on all aspects of industrial exposures and toxicants; this book aids toxicologists, industrial hygienists, and occupational physicians to investigate workplace health problems. • Updates and expands coverage with new chapters covering regulatory toxicology, toxicity testing, physical hazards, high production volume (HPV) chemicals, and workplace drug use • Includes information on occupational and environmental sources of exposure, mammalian toxicology, industrial hygiene, medical management and ecotoxicology • Retains a succinct chapter format that has become the hallmark for the previous editions • Distils a vast amount of information into one resource for both academics and professionals

Crystalline Silica

Crystalline Silica PDF Author: Society for Mining, Metallurgy, and Exploration (U.S.)
Publisher: SME
ISBN: 0873351665
Category : Medical
Languages : en
Pages : 57

Book Description
In practical language, Crystalline Silica addresses what crystalline silica is, where it is found and used, and how it is identified. In addition, the book discusses the regulatory decisions yielding new interest in this ubiquitous substance and presents an overview of the techniques used to determine its presence and abundance. A list of selected readings and supplemental resources and a glossary of terms beyond the scope of this publication round out the text.

Encyclopedia of Respiratory Medicine

Encyclopedia of Respiratory Medicine PDF Author: Geoffrey J. Laurent
Publisher: Academic Press
ISBN:
Category : Medical
Languages : en
Pages : 680

Book Description
An impressive four-volume work that provides an authoritative and comprehensive coverage of the complete field of respiratory medicine. It provides a vital interface between the pure and clinical science environments covering all aspects of respiratory medicine from the relevant molecular biology to the treatment of diseases that affect the respiratory system. It includes comprehensive coverage of lung cells, the structural components of the lung and key molecules that regulate lung function as well as all the major respiratory diseases. Students, researchers and professionals alike will find this an authoritative source of information on all aspects of respiratory medicine. Also available online via ScienceDirect (2006) - featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedirect.com. Includes diagrams of uniformly high quality and references to enable readers to access the wider literature Highly structured through the use of chapter templates Key four-color illustrations that will be invaluable teaching tools

Health Effects of Occupational Exposure to Respirable Crystalline Silica

Health Effects of Occupational Exposure to Respirable Crystalline Silica PDF Author:
Publisher:
ISBN:
Category : Industrial hygiene
Languages : en
Pages : 154

Book Description


Silicosis and Role of IL-6

Silicosis and Role of IL-6 PDF Author: Haushila Prasad Pandey
Publisher: LAP Lambert Academic Publishing
ISBN: 9783848408078
Category :
Languages : en
Pages : 60

Book Description
Silica induced lung fibrosis otherwise known as Silicosis. It is irreversible fibrosis of the lungs caused by inhalation of free silica dust. It is estimated that about million of people are working in various types of mines, ceramics, potteries, foundries, metal grinding, stone crushing, agate grinding, slate pencil industry etc., and occupationally exposed to free silica dust and are at potential risk of developing silicosis. Silica induces different kinds of pro-inflammatory cytokines that help in progression of disease. IL-6 is one of the pro-inflammatory cytokines that produce after silica exposure in lung. In the present book silicosis, parthenogenesis of silicosis and role of IL-6 have been discussed.

The Teaching Files

The Teaching Files PDF Author: C. Isabela S. Silva
Publisher: Elsevier Health Sciences
ISBN: 141606110X
Category : Medical
Languages : en
Pages : 437

Book Description
"Practical and clinically focused, this Chest title in the new Teaching Files Series provides you with 200 interesting and well-presented cases and nearly 600 high-quality images to help you better diagnose any disease of the chest. Experts in the field, Drs. Muller and Silva, use a logical organization throughout, making referencing difficult diagnoses easier than ever before. Detailed discussions of today's modalities and technologies keep you up to date, and challenging diagnostic questions probe your knowledge of the material. This unique, case-based resource offers you an ideal way to sharpen your diagnostic skills and study for exams. And, with Expert Consult functionality, you'll have convenient access to the full text online, all of the book's illustrations, additional cases and images, and links to Medline at expertconsult.com."--Page [4] de la couv.

Occupational and Environmental Lung Disease

Occupational and Environmental Lung Disease PDF Author: Johanna Feary
Publisher: European Respiratory Society
ISBN: 184984125X
Category : Medical
Languages : en
Pages : 353

Book Description
This Monograph provides the general respiratory physician with a working reference based on the latest literature and expert opinion. The initial chapter provides a contemporaneous global perspective of the epidemiology of occupational and environmental lung diseases in an ever-evolving landscape. The book then goes on to consider specific occupational lung diseases. Each chapters has a clear clinical focus and considers: key questions to ask in the history; appropriate investigations to undertake; differential diagnoses; and management. Controversies or diagnostic conundrums encountered in the clinic are also considered, and further chapters are more broadly centred on the non-workplace environment; specifically, the respiratory symptoms and diseases associated with both the outdoor and indoor environments.