Author: Hannes Hauswedell
Publisher: Springer Nature
ISBN: 3030909905
Category : Computers
Languages : en
Pages : 350
Book Description
This is a book about software engineering, bioinformatics, the C++ programming language and the SeqAn library. In the broadest sense, it will help the reader create better, faster and more reliable software by deepening their understanding of available tools, language features, techniques and design patterns. Every developer who previously worked with C++ will enjoy the in-depth chapter on important changes in the language from C++11 up to and including C++20. In contrast to many resources on Modern C++ that present new features only in small isolated examples, this book represents a more holistic approach: readers will understand the relevance of new features and how they interact in the context of a large software project and not just within a "toy example". Previous experience in creating software with C++ is highly recommended to fully appreciate these aspects. SeqAn3 is a new, re-designed software library. The conception and implementation process is detailed in this book, including a critical reflection on the previous versions of the library. This is particularly helpful to readers who are about to create a large software project themselves, or who are planning a major overhaul of an existing library or framework. While the focus of the book is clearly on software development and design, it also touches on various organisational and administrative aspects like licensing, dependency management and quality control.
Sequence Analysis and Modern C++
Author: Hannes Hauswedell
Publisher: Springer Nature
ISBN: 3030909905
Category : Computers
Languages : en
Pages : 350
Book Description
This is a book about software engineering, bioinformatics, the C++ programming language and the SeqAn library. In the broadest sense, it will help the reader create better, faster and more reliable software by deepening their understanding of available tools, language features, techniques and design patterns. Every developer who previously worked with C++ will enjoy the in-depth chapter on important changes in the language from C++11 up to and including C++20. In contrast to many resources on Modern C++ that present new features only in small isolated examples, this book represents a more holistic approach: readers will understand the relevance of new features and how they interact in the context of a large software project and not just within a "toy example". Previous experience in creating software with C++ is highly recommended to fully appreciate these aspects. SeqAn3 is a new, re-designed software library. The conception and implementation process is detailed in this book, including a critical reflection on the previous versions of the library. This is particularly helpful to readers who are about to create a large software project themselves, or who are planning a major overhaul of an existing library or framework. While the focus of the book is clearly on software development and design, it also touches on various organisational and administrative aspects like licensing, dependency management and quality control.
Publisher: Springer Nature
ISBN: 3030909905
Category : Computers
Languages : en
Pages : 350
Book Description
This is a book about software engineering, bioinformatics, the C++ programming language and the SeqAn library. In the broadest sense, it will help the reader create better, faster and more reliable software by deepening their understanding of available tools, language features, techniques and design patterns. Every developer who previously worked with C++ will enjoy the in-depth chapter on important changes in the language from C++11 up to and including C++20. In contrast to many resources on Modern C++ that present new features only in small isolated examples, this book represents a more holistic approach: readers will understand the relevance of new features and how they interact in the context of a large software project and not just within a "toy example". Previous experience in creating software with C++ is highly recommended to fully appreciate these aspects. SeqAn3 is a new, re-designed software library. The conception and implementation process is detailed in this book, including a critical reflection on the previous versions of the library. This is particularly helpful to readers who are about to create a large software project themselves, or who are planning a major overhaul of an existing library or framework. While the focus of the book is clearly on software development and design, it also touches on various organisational and administrative aspects like licensing, dependency management and quality control.
Virus Bioinformatics
Author: Manja Marz
Publisher: MDPI
ISBN: 3039218824
Category : Science
Languages : en
Pages : 330
Book Description
Virus bioinformatics is evolving and succeeding as an area of research in its own right, representing the interface of virology and computer science. Bioinformatic approaches to investigate viral infections and outbreaks have become central to virology research, and have been successfully used to detect, control, and treat infections of humans and animals. As part of the Third Annual Meeting of the European Virus Bioinformatics Center (EVBC), we have published this Special Issue on Virus Bioinformatics.
Publisher: MDPI
ISBN: 3039218824
Category : Science
Languages : en
Pages : 330
Book Description
Virus bioinformatics is evolving and succeeding as an area of research in its own right, representing the interface of virology and computer science. Bioinformatic approaches to investigate viral infections and outbreaks have become central to virology research, and have been successfully used to detect, control, and treat infections of humans and animals. As part of the Third Annual Meeting of the European Virus Bioinformatics Center (EVBC), we have published this Special Issue on Virus Bioinformatics.
From Mathematics to Generic Programming
Author: Alexander A. Stepanov
Publisher: Addison-Wesley Professional
ISBN: 0133491781
Category : Computers
Languages : en
Pages : 311
Book Description
In this substantive yet accessible book, pioneering software designer Alexander Stepanov and his colleague Daniel Rose illuminate the principles of generic programming and the mathematical concept of abstraction on which it is based, helping you write code that is both simpler and more powerful. If you’re a reasonably proficient programmer who can think logically, you have all the background you’ll need. Stepanov and Rose introduce the relevant abstract algebra and number theory with exceptional clarity. They carefully explain the problems mathematicians first needed to solve, and then show how these mathematical solutions translate to generic programming and the creation of more effective and elegant code. To demonstrate the crucial role these mathematical principles play in many modern applications, the authors show how to use these results and generalized algorithms to implement a real-world public-key cryptosystem. As you read this book, you’ll master the thought processes necessary for effective programming and learn how to generalize narrowly conceived algorithms to widen their usefulness without losing efficiency. You’ll also gain deep insight into the value of mathematics to programming—insight that will prove invaluable no matter what programming languages and paradigms you use. You will learn about How to generalize a four thousand-year-old algorithm, demonstrating indispensable lessons about clarity and efficiency Ancient paradoxes, beautiful theorems, and the productive tension between continuous and discrete A simple algorithm for finding greatest common divisor (GCD) and modern abstractions that build on it Powerful mathematical approaches to abstraction How abstract algebra provides the idea at the heart of generic programming Axioms, proofs, theories, and models: using mathematical techniques to organize knowledge about your algorithms and data structures Surprising subtleties of simple programming tasks and what you can learn from them How practical implementations can exploit theoretical knowledge
Publisher: Addison-Wesley Professional
ISBN: 0133491781
Category : Computers
Languages : en
Pages : 311
Book Description
In this substantive yet accessible book, pioneering software designer Alexander Stepanov and his colleague Daniel Rose illuminate the principles of generic programming and the mathematical concept of abstraction on which it is based, helping you write code that is both simpler and more powerful. If you’re a reasonably proficient programmer who can think logically, you have all the background you’ll need. Stepanov and Rose introduce the relevant abstract algebra and number theory with exceptional clarity. They carefully explain the problems mathematicians first needed to solve, and then show how these mathematical solutions translate to generic programming and the creation of more effective and elegant code. To demonstrate the crucial role these mathematical principles play in many modern applications, the authors show how to use these results and generalized algorithms to implement a real-world public-key cryptosystem. As you read this book, you’ll master the thought processes necessary for effective programming and learn how to generalize narrowly conceived algorithms to widen their usefulness without losing efficiency. You’ll also gain deep insight into the value of mathematics to programming—insight that will prove invaluable no matter what programming languages and paradigms you use. You will learn about How to generalize a four thousand-year-old algorithm, demonstrating indispensable lessons about clarity and efficiency Ancient paradoxes, beautiful theorems, and the productive tension between continuous and discrete A simple algorithm for finding greatest common divisor (GCD) and modern abstractions that build on it Powerful mathematical approaches to abstraction How abstract algebra provides the idea at the heart of generic programming Axioms, proofs, theories, and models: using mathematical techniques to organize knowledge about your algorithms and data structures Surprising subtleties of simple programming tasks and what you can learn from them How practical implementations can exploit theoretical knowledge
The Standard ML Basis Library
Author: Emden R. Gansner
Publisher: Cambridge University Press
ISBN: 9781139451406
Category : Computers
Languages : en
Pages : 486
Book Description
The book provides a description of the Standard ML (SML) Basis Library, the standard library for the SML language. For programmers using SML, it provides a complete description of the modules, types and functions composing the library, which is supported by all conforming implementations of the language. The book serves as a programmer's reference, providing manual pages with concise descriptions. In addition, it presents the principles and rationales used in designing the library, and relates these to idioms and examples for using the library. A particular emphasis of the library is to encourage the use of SML in serious system programming. Major features of the library include I/O, a large collection of primitive types, support for internationalization, and a portable operating system interface. This manual will be an indispensable reference for students, professional programmers, and language designers.
Publisher: Cambridge University Press
ISBN: 9781139451406
Category : Computers
Languages : en
Pages : 486
Book Description
The book provides a description of the Standard ML (SML) Basis Library, the standard library for the SML language. For programmers using SML, it provides a complete description of the modules, types and functions composing the library, which is supported by all conforming implementations of the language. The book serves as a programmer's reference, providing manual pages with concise descriptions. In addition, it presents the principles and rationales used in designing the library, and relates these to idioms and examples for using the library. A particular emphasis of the library is to encourage the use of SML in serious system programming. Major features of the library include I/O, a large collection of primitive types, support for internationalization, and a portable operating system interface. This manual will be an indispensable reference for students, professional programmers, and language designers.
Networks in Systems Biology
Author: Fabricio Alves Barbosa da Silva
Publisher: Springer Nature
ISBN: 3030518620
Category : Computers
Languages : en
Pages : 381
Book Description
This book presents a range of current research topics in biological network modeling, as well as its application in studies on human hosts, pathogens, and diseases. Systems biology is a rapidly expanding field that involves the study of biological systems through the mathematical modeling and analysis of large volumes of biological data. Gathering contributions from renowned experts in the field, some of the topics discussed in depth here include networks in systems biology, the computational modeling of multidrug-resistant bacteria, and systems biology of cancer. Given its scope, the book is intended for researchers, advanced students, and practitioners of systems biology. The chapters are research-oriented, and present some of the latest findings on their respective topics.
Publisher: Springer Nature
ISBN: 3030518620
Category : Computers
Languages : en
Pages : 381
Book Description
This book presents a range of current research topics in biological network modeling, as well as its application in studies on human hosts, pathogens, and diseases. Systems biology is a rapidly expanding field that involves the study of biological systems through the mathematical modeling and analysis of large volumes of biological data. Gathering contributions from renowned experts in the field, some of the topics discussed in depth here include networks in systems biology, the computational modeling of multidrug-resistant bacteria, and systems biology of cancer. Given its scope, the book is intended for researchers, advanced students, and practitioners of systems biology. The chapters are research-oriented, and present some of the latest findings on their respective topics.
ACS Style Guide
Author: Anne M. Coghill
Publisher: American Chemical Society
ISBN: 9780841239494
Category : Authorship
Languages : en
Pages : 0
Book Description
In the time since the second edition of The ACS Style Guide was published, the rapid growth of electronic communication has dramatically changed the scientific, technical, and medical (STM) publication world. This dynamic mode of dissemination is enabling scientists, engineers, and medicalpractitioners all over the world to obtain and transmit information quickly and easily. An essential constant in this changing environment is the requirement that information remain accurate, clear, unambiguous, and ethically sound.This extensive revision of The ACS Style Guide thoroughly examines electronic tools now available to assist STM writers in preparing manuscripts and communicating with publishers. Valuable updates include discussions of markup languages, citation of electronic sources, online submission ofmanuscripts, and preparation of figures, tables, and structures. In keeping current with the changing environment, this edition also contains references to many resources on the internet.With this wealth of new information, The ACS Style Guide's Third Edition continues its long tradition of providing invaluable insight on ethics in scientific communication, the editorial process, copyright, conventions in chemistry, grammar, punctuation, spelling, and writing style for any STMauthor, reviewer, or editor. The Third Edition is the definitive source for all information needed to write, review, submit, and edit scholarly and scientific manuscripts.
Publisher: American Chemical Society
ISBN: 9780841239494
Category : Authorship
Languages : en
Pages : 0
Book Description
In the time since the second edition of The ACS Style Guide was published, the rapid growth of electronic communication has dramatically changed the scientific, technical, and medical (STM) publication world. This dynamic mode of dissemination is enabling scientists, engineers, and medicalpractitioners all over the world to obtain and transmit information quickly and easily. An essential constant in this changing environment is the requirement that information remain accurate, clear, unambiguous, and ethically sound.This extensive revision of The ACS Style Guide thoroughly examines electronic tools now available to assist STM writers in preparing manuscripts and communicating with publishers. Valuable updates include discussions of markup languages, citation of electronic sources, online submission ofmanuscripts, and preparation of figures, tables, and structures. In keeping current with the changing environment, this edition also contains references to many resources on the internet.With this wealth of new information, The ACS Style Guide's Third Edition continues its long tradition of providing invaluable insight on ethics in scientific communication, the editorial process, copyright, conventions in chemistry, grammar, punctuation, spelling, and writing style for any STMauthor, reviewer, or editor. The Third Edition is the definitive source for all information needed to write, review, submit, and edit scholarly and scientific manuscripts.
Generic Programming
Author: Mehdi Jazayeri
Publisher: Springer
ISBN: 3540399534
Category : Computers
Languages : en
Pages : 280
Book Description
This book constitutes the thoroughly refereed post-proceedings of the International Seminar on Generic Programming held in Dagstuhl Castle, Germany in April/May 1998.The 20 revised full papers were carefully reviewed for inclusion in the book. As the first book entirely devoted to the new paradigm of generic programming, this collection offers topical sections on foundations and methodology comparisons, programming methodology, language design, and applications.
Publisher: Springer
ISBN: 3540399534
Category : Computers
Languages : en
Pages : 280
Book Description
This book constitutes the thoroughly refereed post-proceedings of the International Seminar on Generic Programming held in Dagstuhl Castle, Germany in April/May 1998.The 20 revised full papers were carefully reviewed for inclusion in the book. As the first book entirely devoted to the new paradigm of generic programming, this collection offers topical sections on foundations and methodology comparisons, programming methodology, language design, and applications.
The Art of the Metaobject Protocol
Author: Gregor Kiczales
Publisher: MIT Press
ISBN: 9780262610742
Category : Computers
Languages : en
Pages : 352
Book Description
The authors introduce this new approach to programming language design, describe its evolution and design principles, and present a formal specification of a metaobject protocol for CLOS. The CLOS metaobject protocol is an elegant, high-performance extension to the CommonLisp Object System. The authors, who developed the metaobject protocol and who were among the group that developed CLOS, introduce this new approach to programming language design, describe its evolution and design principles, and present a formal specification of a metaobject protocol for CLOS. Kiczales, des Rivières, and Bobrow show that the "art of metaobject protocol design" lies in creating a synthetic combination of object-oriented and reflective techniques that can be applied under existing software engineering considerations to yield a new approach to programming language design that meets a broad set of design criteria. One of the major benefits of including the metaobject protocol in programming languages is that it allows users to adjust the language to better suit their needs. Metaobject protocols also disprove the adage that adding more flexibility to a programming language reduces its performance. In presenting the principles of metaobject protocols, the authors work with actual code for a simplified implementation of CLOS and its metaobject protocol, providing an opportunity for the reader to gain hands-on experience with the design process. They also include a number of exercises that address important concerns and open issues. Gregor Kiczales and Jim des Rivières, are Members of the Research Staff, and Daniel Bobrow is a Research Fellow, in the System Sciences Laboratory at Xerox Palo Alto Research Center.
Publisher: MIT Press
ISBN: 9780262610742
Category : Computers
Languages : en
Pages : 352
Book Description
The authors introduce this new approach to programming language design, describe its evolution and design principles, and present a formal specification of a metaobject protocol for CLOS. The CLOS metaobject protocol is an elegant, high-performance extension to the CommonLisp Object System. The authors, who developed the metaobject protocol and who were among the group that developed CLOS, introduce this new approach to programming language design, describe its evolution and design principles, and present a formal specification of a metaobject protocol for CLOS. Kiczales, des Rivières, and Bobrow show that the "art of metaobject protocol design" lies in creating a synthetic combination of object-oriented and reflective techniques that can be applied under existing software engineering considerations to yield a new approach to programming language design that meets a broad set of design criteria. One of the major benefits of including the metaobject protocol in programming languages is that it allows users to adjust the language to better suit their needs. Metaobject protocols also disprove the adage that adding more flexibility to a programming language reduces its performance. In presenting the principles of metaobject protocols, the authors work with actual code for a simplified implementation of CLOS and its metaobject protocol, providing an opportunity for the reader to gain hands-on experience with the design process. They also include a number of exercises that address important concerns and open issues. Gregor Kiczales and Jim des Rivières, are Members of the Research Staff, and Daniel Bobrow is a Research Fellow, in the System Sciences Laboratory at Xerox Palo Alto Research Center.
Advances in Artificial Intelligence, Computation, and Data Science
Author: Tuan D. Pham
Publisher: Springer Nature
ISBN: 303069951X
Category : Science
Languages : en
Pages : 373
Book Description
Artificial intelligence (AI) has become pervasive in most areas of research and applications. While computation can significantly reduce mental efforts for complex problem solving, effective computer algorithms allow continuous improvement of AI tools to handle complexity—in both time and memory requirements—for machine learning in large datasets. Meanwhile, data science is an evolving scientific discipline that strives to overcome the hindrance of traditional skills that are too limited to enable scientific discovery when leveraging research outcomes. Solutions to many problems in medicine and life science, which cannot be answered by these conventional approaches, are urgently needed for society. This edited book attempts to report recent advances in the complementary domains of AI, computation, and data science with applications in medicine and life science. The benefits to the reader are manifold as researchers from similar or different fields can be aware of advanced developments and novel applications that can be useful for either immediate implementations or future scientific pursuit. Features: Considers recent advances in AI, computation, and data science for solving complex problems in medicine, physiology, biology, chemistry, and biochemistry Provides recent developments in three evolving key areas and their complementary combinations: AI, computation, and data science Reports on applications in medicine and physiology, including cancer, neuroscience, and digital pathology Examines applications in life science, including systems biology, biochemistry, and even food technology This unique book, representing research from a team of international contributors, has not only real utility in academia for those in the medical and life sciences communities, but also a much wider readership from industry, science, and other areas of technology and education.
Publisher: Springer Nature
ISBN: 303069951X
Category : Science
Languages : en
Pages : 373
Book Description
Artificial intelligence (AI) has become pervasive in most areas of research and applications. While computation can significantly reduce mental efforts for complex problem solving, effective computer algorithms allow continuous improvement of AI tools to handle complexity—in both time and memory requirements—for machine learning in large datasets. Meanwhile, data science is an evolving scientific discipline that strives to overcome the hindrance of traditional skills that are too limited to enable scientific discovery when leveraging research outcomes. Solutions to many problems in medicine and life science, which cannot be answered by these conventional approaches, are urgently needed for society. This edited book attempts to report recent advances in the complementary domains of AI, computation, and data science with applications in medicine and life science. The benefits to the reader are manifold as researchers from similar or different fields can be aware of advanced developments and novel applications that can be useful for either immediate implementations or future scientific pursuit. Features: Considers recent advances in AI, computation, and data science for solving complex problems in medicine, physiology, biology, chemistry, and biochemistry Provides recent developments in three evolving key areas and their complementary combinations: AI, computation, and data science Reports on applications in medicine and physiology, including cancer, neuroscience, and digital pathology Examines applications in life science, including systems biology, biochemistry, and even food technology This unique book, representing research from a team of international contributors, has not only real utility in academia for those in the medical and life sciences communities, but also a much wider readership from industry, science, and other areas of technology and education.
Automated Reasoning for Systems Biology and Medicine
Author: Pietro Liò
Publisher: Springer
ISBN: 303017297X
Category : Computers
Languages : en
Pages : 471
Book Description
This book presents outstanding contributions in an exciting, new and multidisciplinary research area: the application of formal, automated reasoning techniques to analyse complex models in systems biology and systems medicine. Automated reasoning is a field of computer science devoted to the development of algorithms that yield trustworthy answers, providing a basis of sound logical reasoning. For example, in the semiconductor industry formal verification is instrumental to ensuring that chip designs are free of defects (or “bugs”). Over the past 15 years, systems biology and systems medicine have been introduced in an attempt to understand the enormous complexity of life from a computational point of view. This has generated a wealth of new knowledge in the form of computational models, whose staggering complexity makes manual analysis methods infeasible. Sound, trusted, and automated means of analysing the models are thus required in order to be able to trust their conclusions. Above all, this is crucial to engineering safe biomedical devices and to reducing our reliance on wet-lab experiments and clinical trials, which will in turn produce lower economic and societal costs. Some examples of the questions addressed here include: Can we automatically adjust medications for patients with multiple chronic conditions? Can we verify that an artificial pancreas system delivers insulin in a way that ensures Type 1 diabetic patients never suffer from hyperglycaemia or hypoglycaemia? And lastly, can we predict what kind of mutations a cancer cell is likely to undergo? This book brings together leading researchers from a number of highly interdisciplinary areas, including: · Parameter inference from time series · Model selection · Network structure identification · Machine learning · Systems medicine · Hypothesis generation from experimental data · Systems biology, systems medicine, and digital pathology · Verification of biomedical devices “This book presents a comprehensive spectrum of model-focused analysis techniques for biological systems ...an essential resource for tracking the developments of a fast moving field that promises to revolutionize biology and medicine by the automated analysis of models and data.”Prof Luca Cardelli FRS, University of Oxford
Publisher: Springer
ISBN: 303017297X
Category : Computers
Languages : en
Pages : 471
Book Description
This book presents outstanding contributions in an exciting, new and multidisciplinary research area: the application of formal, automated reasoning techniques to analyse complex models in systems biology and systems medicine. Automated reasoning is a field of computer science devoted to the development of algorithms that yield trustworthy answers, providing a basis of sound logical reasoning. For example, in the semiconductor industry formal verification is instrumental to ensuring that chip designs are free of defects (or “bugs”). Over the past 15 years, systems biology and systems medicine have been introduced in an attempt to understand the enormous complexity of life from a computational point of view. This has generated a wealth of new knowledge in the form of computational models, whose staggering complexity makes manual analysis methods infeasible. Sound, trusted, and automated means of analysing the models are thus required in order to be able to trust their conclusions. Above all, this is crucial to engineering safe biomedical devices and to reducing our reliance on wet-lab experiments and clinical trials, which will in turn produce lower economic and societal costs. Some examples of the questions addressed here include: Can we automatically adjust medications for patients with multiple chronic conditions? Can we verify that an artificial pancreas system delivers insulin in a way that ensures Type 1 diabetic patients never suffer from hyperglycaemia or hypoglycaemia? And lastly, can we predict what kind of mutations a cancer cell is likely to undergo? This book brings together leading researchers from a number of highly interdisciplinary areas, including: · Parameter inference from time series · Model selection · Network structure identification · Machine learning · Systems medicine · Hypothesis generation from experimental data · Systems biology, systems medicine, and digital pathology · Verification of biomedical devices “This book presents a comprehensive spectrum of model-focused analysis techniques for biological systems ...an essential resource for tracking the developments of a fast moving field that promises to revolutionize biology and medicine by the automated analysis of models and data.”Prof Luca Cardelli FRS, University of Oxford