Naturally Occurring Pyrrolizidine Alkaloids PDF Download
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Author: Dr. Abdel-Fatta Rizk Publisher: CRC Press ISBN: 9780849346507 Category : Science Languages : en Pages : 244
Book Description
Plants containing pyrrolizidine alkaloids are so numerous and widespread that they can be expected to be present in most environments. About 200 pyrrolizidine alkaloids have been isolated and identified from different plants. Interest in these alkaloids has increased in recent years due to their causative effects in the heavy loss of livestock in many countries. Naturally Occurring Pyrrolizidine Alkaloids discusses the plant sources and properties of pyrrolizidine alkaloids; extraction, fractionation and identification; various methods of spectrometry of pyrrolizidine alkaloids; quantitative determination; and the toxicity, carcinogenicity, pharmacology, and other biological activities of pyrrolizidine alkaloids. Researchers in veterinary and human medicine will find this book to be a fascinating and useful reference tool.
Author: Dr. Abdel-Fatta Rizk Publisher: CRC Press ISBN: 9780849346507 Category : Science Languages : en Pages : 244
Book Description
Plants containing pyrrolizidine alkaloids are so numerous and widespread that they can be expected to be present in most environments. About 200 pyrrolizidine alkaloids have been isolated and identified from different plants. Interest in these alkaloids has increased in recent years due to their causative effects in the heavy loss of livestock in many countries. Naturally Occurring Pyrrolizidine Alkaloids discusses the plant sources and properties of pyrrolizidine alkaloids; extraction, fractionation and identification; various methods of spectrometry of pyrrolizidine alkaloids; quantitative determination; and the toxicity, carcinogenicity, pharmacology, and other biological activities of pyrrolizidine alkaloids. Researchers in veterinary and human medicine will find this book to be a fascinating and useful reference tool.
Author: R. H. F. Manske Publisher: Elsevier ISBN: 1483221954 Category : Medical Languages : en Pages : 534
Book Description
The Alkaloids: Chemistry and Physiology, Volume I deals with the chemistry and pharmacology of the alkaloids. This book discusses the sources of alkaloids and their isolation, alkaloids in grafts, position in nitrogen metabolism, and factors affecting alkaloid formation. The structure of the necic acids, common sources of different senecio alkaloids, alkaloids of hemlock, and chemistry of the tropane alkaloids are also elaborated. This text likewise covers the elucidation of the structure of strychnine and brucine; consequences of alkaloid formation; and structure of the alkaloids. This volume is a good source for chemists and researchers interested in the field of alkaloid chemistry.
Author: Paul M. Dewick Publisher: John Wiley & Sons ISBN: 9780471496410 Category : Medical Languages : en Pages : 524
Book Description
This guide covers classes of natural products in medicine, whether derived from plants, micro-organisms or animals. Structured according to biosynthetic pathway, it is written from a chemistry-based approach.
Author: Helmut Wiedenfeld Publisher: Vandenhoeck & Ruprecht ISBN: 3899714261 Category : Pyrrolizidines Languages : en Pages : 145
Book Description
Pyrrolizidine alkaloids show only minor toxicity in their native state, but are metabolized in the human or animal organisms to carcinogenic, teratogenic and mutagenic compounds, with the precise structure of these compounds being responsible for the metabolic toxification process. Therefore, to be able to evaluate the toxic potential of each alkaloid, it is essential to exactly know the structure of the respective compound. X-ray structure analysis is the appropriate method both for elucidating the structure and for determining other parameters, such as the lengths of the bonds that influence the metabolic process. This book describes the incidence and the process of the intoxication as well as the possibilities to how the substances may reach the organism. In addition, the compounds elucidated by X-ray structure analysis to date are shown in their three-dimensional structure and structure-toxicity relationships are discussed.Pyrrolizidinalkaloide weisen in nativem Zustand nur geringe Toxizität auf, werden jedoch zu kanzerogenen, teratogenen und mutagenen Verbindungen metabolisiert, wenn sie in den menschlichen oder tierischen Organismus gelangen. Der Verlauf dieser Toxifizierung hängt von der konkreten Struktur dieser Stoffe und weiteren Parametern ab. Zur Bestimmung dieser Faktoren stellt die Röntgenstrukturanalyse die geeignete Methode dar. Im vorliegenden Buch werden das Vorkommen, der Ablauf der Toxifizierung und die Möglichkeiten, wie die Stoffe in den Organismus gelangen können, beschrieben. Es werden die bislang durch Röntgenstrukturanalyse vermessenen Verbindungen in ihrer 3D-Struktur aufgefÃ"hrt und Struktur-Toxizitätsbeziehungen diskutiert.
Author: Dr. Abdel-Fatta Rizk
Author: Dr. Abdel-Fatta Rizk
Author: R. H. F. Manske
Author: Elefterrios Demetrios Coucourakis
Author: Paul M. Dewick
Author: Robert Bruce Jeppsen
Author: 
Author: 
Author: Francis Robert Soer
Author: L. B. Bull
Author: Helmut Wiedenfeld