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Author: Thomas Ming Swi Chang Publisher: World Scientific ISBN: 9814472867 Category : Medical Languages : en Pages : 599
Book Description
Nanomedicine consists of the use of nanotechnology and nanobiotechnology in medicine. There have been extensive developments in the area of nanomedicine. The scope of this book is first to discuss the origin of nanomedicine. Following this, instead of a general overview of the whole area, 24 chapters on selected topics of important areas are described in detail. Authors are selected from around the world to give a representative and international view of the activities in the area of nanomedicine.
Author: Thomas Ming Swi Chang Publisher: World Scientific ISBN: 9814472875 Category : Medical Languages : en Pages : 600
Book Description
Nanomedicine consists of the use of nanotechnology and nanobiotechnology in medicine. There have been extensive developments in the area of nanomedicine. The scope of this book is first to discuss the origin of nanomedicine. Following this, instead of a general overview of the whole area, 24 chapters on selected topics of important areas are described in detail. Authors are selected from around the world to give a representative and international view of the activities in the area of nanomedicine. Contents:Artificial Cells: The Beginning of Nanomedicine (Thomas Ming Swi Chang)The Clinical Development of Hemopure®: A Selective Commentary (A Gerson Greenburg)Glutaraldehyde Polymerized Porcine Hemoglobin: Preparation, Safety Evaluation and Pharmacodynamics Study (Chao Chen, Hongli Zhu and Kunping Yan)Evidence Regarding Some Pharmacologic Characteristics of Hemoglobin-Based Oxygen Carriers (Enrico Bucci)EAF PEG Hemoglobins: Novel Class of Nonhypertensive Resuscitation Fluids: Simplicity and Advantages of Extension Arm Chemistry for PEGylation (Seetharama A Acharya, Amy G Tsai and Marcos Intaglietta)Biocompatibility of a Highly Concentrated Fluid of Hemoglobin-Vesicles as a Transfusion Alternative (Hiromi Sakai)Molecular Basis of Haptoglobin and Hemoglobin Complex Formation and Protection against Oxidative Stress and Damage (Yiping Jia and Abdu I Alayash)Polynitroxylated Hemoglobin as a Multifunctional Therapeutic for Critical Care and Transfusion Medicine (Li Ma and Carleton Jen Chang Hsia)Surface-Mediated Drug Delivery (Benjamin M Wohl, Betina Fejerskov, Siow-Feng Chong and Alexander N Zelikin)Use of Tunable Pores for Accurate Characterization of Micro- and Nanoparticle Systems in Nanomedicine (James Eldridge, Aaron H Colby, Geoff R Willmott, Sam Yu and Mark W Grinstaff)Microfluidic Probes to Process Surfaces, Cells, and Tissues (Mohammad A Qasaimeh, Sebastien G Ricoult and David Juncker)Subcompartmentalized Systems Towards Therapeutic Cell Mimics (Leticia Hosta-Rigau and Brigitte Städler)Soft Magnetic Nanomaterials Towards Nanomedicine: Magnetism Principles, Preparation, Characterization and Potential Applications (G W Qin, S Li, Y P Ren, F Darain and K Dimitrov)GoldMag Composite Particles and Their Applications in Nanomedicine (Mingli Peng, Xu Chao, Chao Chen and Yali Cui)Nanoparticles for Imaging and Therapy: Functionalization, Endocytosis and Characterization (Yu Zhang, Yi Li, Gürer Budak, Mihrimah Ozkan and Cengiz S Ozkan)Noscapines: Novel Carrier Systems to Target Tumor Cells (Ramesh Chandra, J Madan, Prashant Singh, Pradeep Kumar, V Tomar, Sujata K Dass and Ankush Chandra)High-Throughput Methods for Miniaturization of Implantable Artificial Cells (Maryam Mobed-Miremadi)Amphiphilic Core–Shell Nanoparticles Containing Hairy Polyethyleneimine Shells as Effective Nanocarriers for Gene and siRNA Delivery (Pei Li, Yuen Shan Siu, Kin Man Ho and Wei Li)Nano-Chaperones: Nanoparticles Acting as Artificial Chaperones (S Boridy and D Maysinger)Bio-Functional Polymer Vesicles for Applications in Nanomedicine (Hans-Peter M de Hoog, Bo Liedberg and Madhavan Nallani)Carbon Nanotubes in Cancer and Stem Cell Therapeutics (Wei Shao, Arghya Paul and Satya Prakash)Chitosan-Based Nanocarriers for Efficient and Targeted siRNA Delivery (Surendra Nimesh and Ramesh Chandra)Application of Polyethylenimine-Based Nanoparticles for RNA Therapeutics (Surendra Nimesh and Ramesh Chandra)Nanosilver System Technology for Applications in Nanomedicine (Helmut Schmid) Readership: Graduate students and researchers in nanomedicine, nanobiotechnology, nanotechnology, biotechnology and biomedical engineering. Keywords:Nanomedicine;Nanobiotechnology;Nanotechnology;Blood Substitutes;Polyhemoglobin;Oxygen Therapeutics;Antioxidant;Oxygen Radicals;Regenerative Medicine;Nanocapsules;Nanoparticles;Bioencapsulation;Drug Delivery;Magnetic;Conjugated Hemoglobin;Enzymes;Cancer Therapy;Carbon Nanotubule;Microfluidics;Blood;Transfusion;Polyethylene Glycol;Liposome;Polymersomes;Oxidative Stress;Artificial Cells
Author: Andrew T. S. Wee Publisher: World Scientific ISBN: 9812839569 Category : Science Languages : en Pages : 268
Book Description
Scanning probe techniques. Scanning probe microscopy based nanoscale patterning and fabrication / X. N. Xie, H. J. Chung and A. T. S. Wee. Nanoscale characterization by scanning tunneling microscopy / H. Xu ... [et al.] -- Nanofabrication. EUV lithography for semiconductor manufacturing and nanofabrication / H. Kinoshita. Synchrotron-radiation-supported high-aspect-ratio nanofabrication / A. Chen ... [et al.] -- Functional nanomaterials. Chemical interactions at noble metal nanoparticle surfaces - catalysis, sensors and devices / A. S. Nair. Diamond-like carbon : a new material base for nano-architectures / X. Li and D. H. C. Chua. Hotplate technique for nanomaterials / Y. Zhu and C. H. Sow -- Molecular engineering. [Pie symbol]-d interaction based molecular conducting magnets : how to increase the effects of the [Pie symbol]-d interaction / A. Miyazaki and T. Enoki. Recent developments on porphyrin assemblies / R. Charvet ... [et al.] -- Bionanotechnology and nanomedicine. Nanostructures from designer peptides / B. T. Ong, P. K. Ajikumar and S. Valiyaveettil. Nanotechnology and human diseases / G. Y. H. Lee and C. T. Lim. Nanomedicine : nanoparticles of biodegradable polymers for cancer diagnosis and treatment / S. S. Feng.
Author: Yi Guo Publisher: Springer Science & Business Media ISBN: 1441984100 Category : Technology & Engineering Languages : en Pages : 201
Book Description
Micro/Nano-robotics for Biomedical Applications features a system approach and incorporates modern methodologies in autonomous mobile robots for programmable and controllable micro/nano-robots aiming at biomedical applications. The book provides chapters of instructional materials in micro/nanorobotics for biomedical applications. The book features lecture units on micro/nanorobot components and techniques, including sensors, actuator, power supply, and micro/nano-fabrication and assembly. It also contains case studies on using micro/nano-robots in biomedical environments and in biomedicine, as well as a design example to conceptually develop a Vitamin-pill sized robot to enter human’s gastrointestinal tract. Laboratory modules to teach robot navigation and cooperation methods suitable to biomedical applications will be also provided based on existing simulation and robot platforms.
Author: Susan Hua Publisher: Frontiers Media SA ISBN: 2889457451 Category : Languages : en Pages : 155
Book Description
Nanotechnology is a multidisciplinary field that is revolutionizing the way we detect and treat damage to the human body. Nanomedicine applies nanotechnology to highly specific medical interventions for the prevention, diagnosis, and treatment of diseases. They are increasingly being used to overcome biological barriers in the body to improve the way we deliver compounds to specific tissues and organs. In particular, nanomedicines have been shown to be beneficial for stabilizing therapeutic compounds, overcoming obstacles to cellular and tissue uptake, and improving biodistribution of compounds to target sites in vivo. Nanomedicines have demonstrated significant therapeutic advantages for a multitude of biomedical applications, however the clinical translation of these nanotechnology platforms has not progressed as quickly as the plethora of positive results would have suggested. Understanding the advances in nanomedicine to date and the challenges that still need to be overcome, will allow future research to improve on existing platforms and to address the current translational and regulatory limitations. This eBook “Advances and Challenges in Nanomedicine” has brought together experts in the fields of nanomedicine, nanotechnology, nanotoxicology, pharmaceutics, manufacturing, and translation to discuss the application of nanotechnology to drug delivery. This information is presented as original research, opinion, perspective, and review articles. The goal of this eBook is to generate collaborative discussion on the current status, general trends, challenges, strategies, and future direction of pharmaceutical nanotechnology, as well as highlight current and emerging nanoparticulate platforms with potential medical applications.
Author: Bert Müller Publisher: John Wiley & Sons ISBN: 3527338608 Category : Technology & Engineering Languages : en Pages : 416
Book Description
Unique in combining the expertise of practitioners from university hospitals and that of academic researchers, this timely monograph presents selected topics catering specifically to the needs and interests of natural scientists and engineers as well as physicians who are concerned with developing nanotechnology-based treatments to improve human health. To this end, the book cover the materials aspects of nanomedicine, such as the hierarchical structure of biological materials, the imaging of hard and soft tissues and, in particular, concrete examples of nanotechnology-based approaches in modern medical treatments. The whole is rounded off by a discussion of the opportunities and risks of using nanotechnology and nanomaterials in medicine, backed by case studies taken from real life.
Author: Nancy A. Monteiro-Riviere Publisher: CRC Press ISBN: 1482203871 Category : Medical Languages : en Pages : 516
Book Description
Since the first publication of this book in 2007, the field of nanoscience and nanomedicine continues to grow substantially. This second edition, Nanotoxicology: Progress toward Nanomedicine, enlists internationally recognized experts to document the continuing development and rationale for the safe design of engineered nanomaterials (ENM). This includes new improved characterization endpoints, screening, and detection methods for in vitro and in vivo toxicity testing. These tools also contribute greatly to nanosafety research applied to nanomedicines. Topics include The impacts of nanotechnology on biomedicine, including functionalization for tissue-specific targeting, the biointeractions of multifunctional nanoparticle-based therapy, and the ability to control specific physicochemical properties of nanoparticles The requirements for proper detection, measurement, and assessment both for workplace exposure and in consumer products—with a focus on potential health and safety implications Predictive modeling, using quantitative nanostructure activity relationships to predict the pharmacokinetics and biodistribution of nanomaterials in the body Specific methodologies, imaging, and techniques to assess nanomaterials from the manufacturing process to nanomedicine applications Tools for assessing nanoparticle toxicity and the limitations of detection methods for assessing toxicity in both in vivo and in vitro systems and at the single cell and tissue levels Toxicity of nanomaterials to specific organ systems, cell–based targeting to tumors, and other biomedical applications The difficulty of conducting risk assessments and the need for addressing knowledge gaps, especially with long-term studies A roadmap for future research The development of nanotechnology-based products must be complemented with appropriate validated methods to assess, monitor, manage, and reduce the potential risks of ENM to human health and the environment. This volume provides a cogent survey of advances in this area by a well-respected and diverse group of international scientists.
Author: Surendra Nimesh Publisher: Woodhead Publishing ISBN: 0081005636 Category : Science Languages : en Pages : 256
Book Description
Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance. The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc. Provides a complete overview of the applicatiosn of nanomedicine in the delivery of nucleic acids, from characterization of nanoparticles, to in vitro and in vivo studies Discusses delivery issues of less well explored nucleic acids, like PNAs, Ribozymes, DNAzymes, etc. Summarizes the current state of research in nucleic acid delivery and underscores the future of nanomedicine in this field
Author: Raj Bawa Publisher: CRC Press ISBN: 9814669237 Category : Medical Languages : en Pages : 1502
Book Description
This unique handbook (60 chapters) examines the entire "product life cycle," from the creation of nanomedical products to their final market introduction. While focusing on critical issues relevant to nanoproduct development and translational activities, it tackles topics such as regulatory science, patent law, FDA law, ethics, personalized medicine, risk analysis, toxicology, nano-characterization and commercialization activities. A separate section provides fascinating perspectives and editorials from leading experts in this complex interdisciplinary field.
Author: Thomas Ming Swi Chang
Author: Thomas Ming Swi Chang
Author: Andrew T. S. Wee
Author: Andrew T. S. Wee
Author: 
Author: Yi Guo
Author: Susan Hua
Author: Bert Müller
Author: Nancy A. Monteiro-Riviere
Author: Surendra Nimesh
Author: Raj Bawa