Scientific Report on the Investigations of the Imperial Cancer Research Fund PDF Download

Author: Cancer Research Fund (Great Britain)
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 288

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Author: Imperial Cancer Research Fund (Great Britain)
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 134

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Author:
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 52

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Author: Imperial Cancer Research Fund (Great Britain)
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 324

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Author: Charles Swanton
Publisher: Perspectives Cshl
ISBN: 9781621821434
Category : Medical
Languages : en
Pages : 350

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Book Description
Tumor progression is driven by mutations that confer growth advantages to different subpopulations of cancer cells. As a tumor grows, these subpopulations expand, accumulate new mutations, and are subjected to selective pressures from the environment, including anticancer interventions. This process, termed clonal evolution, can lead to the emergence of therapy-resistant tumors and poses a major challenge for cancer eradication efforts. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines cancer progression as an evolutionary process and explores how this way of looking at cancer may lead to more effective strategies for managing and treating it. The contributors review efforts to characterize the subclonal architecture and dynamics of tumors, understand the roles of chromosomal instability, driver mutations, and mutation order, and determine how cancer cells respond to selective pressures imposed by anticancer agents, immune cells, and other components of the tumor microenvironment. They compare cancer evolution to organismal evolution and describe how ecological theories and mathematical models are being used to understand the complex dynamics between a tumor and its microenvironment during cancer progression. The authors also discuss improved methods to monitor tumor evolution (e.g., liquid biopsies) and the development of more effective strategies for managing and treating cancers (e.g., immunotherapies). This volume will therefore serve as a vital reference for all cancer biologists as well as anyone seeking to improve clinical outcomes for patients with cancer.

Author: Imperial Cancer Research Fund (Great
Publisher: Legare Street Press
ISBN: 9781019744284
Category :
Languages : en
Pages : 0

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A scientific report detailing the Imperial Cancer Research Fund's investigations under the direction of the Royal College of Physicians of London and the Royal College of Surgeons of England. This book is intended for medical researchers, oncologists, and anyone interested in cancer research. This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Author: Kongelige Danske videnskabernes selskab
Publisher:
ISBN:
Category : Biology
Languages : en
Pages : 534

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Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1516

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A keyword listing of serial titles currently received by the National Library of Medicine.

Author: Philippines. Bureau of Science
Publisher:
ISBN:
Category :
Languages : en
Pages : 582

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Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 798

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