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Magnesium in the Central Nervous System

Magnesium in the Central Nervous System PDF Author: Robert Vink
Publisher: University of Adelaide Press
ISBN: 0987073052
Category : Medical
Languages : en
Pages : 354

Book Description
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Magnesium in the Central Nervous System

Magnesium in the Central Nervous System PDF Author: Robert Vink
Publisher: University of Adelaide Press
ISBN: 0987073052
Category : Medical
Languages : en
Pages : 354

Book Description
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Diagnostic and Statistical Manual of Mental Disorders (DSM-5)

Diagnostic and Statistical Manual of Mental Disorders (DSM-5) PDF Author: American Psychiatric Association
Publisher: American Psychiatric Publishing
ISBN: 9781955245180
Category :
Languages : en
Pages :

Book Description


Schizophrenia and Bipolar Disorders

Schizophrenia and Bipolar Disorders PDF Author: Herbert Wagemaker
Publisher: Ponte Vedra Publishing
ISBN: 9780965499613
Category : Bipolar disorder
Languages : en
Pages : 162

Book Description


First Episode Psychosis

First Episode Psychosis PDF Author: Katherine J. Aitchison
Publisher: CRC Press
ISBN: 9781853174353
Category : Medical
Languages : en
Pages : 152

Book Description
The new edition of this popular handbook has been thoroughly updated to include the latest data concerning treatment of first-episode patients. Drawing from their experience, the authors discuss the presentation and assessment of the first psychotic episode and review the appropriate use of antipsychotic agents and psychosocial approaches in effective management.

Hidden Valley Road

Hidden Valley Road PDF Author: Robert Kolker
Publisher: Anchor
ISBN: 0385543778
Category : Biography & Autobiography
Languages : en
Pages : 427

Book Description
#1 NEW YORK TIMES BESTSELLER • OPRAH’S BOOK CLUB PICK • ONE OF GQ's TOP 50 BOOKS OF LITERARY JOURNALISM IN THE 21st CENTURY • The heartrending story of a midcentury American family with twelve children, six of them diagnosed with schizophrenia, that became science's great hope in the quest to understand the disease. "Reads like a medical detective journey and sheds light on a topic so many of us face: mental illness." —Oprah Winfrey Don and Mimi Galvin seemed to be living the American dream. After World War II, Don's work with the Air Force brought them to Colorado, where their twelve children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins--aspiration, hard work, upward mobility, domestic harmony--and they worked hard to play their parts. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the ten Galvin boys, one after another, were diagnosed as schizophrenic. How could all this happen to one family? What took place inside the house on Hidden Valley Road was so extraordinary that the Galvins became one of the first families to be studied by the National Institute of Mental Health. Their story offers a shadow history of the science of schizophrenia, from the era of institutionalization, lobotomy, and the schizophrenogenic mother to the search for genetic markers for the disease, always amid profound disagreements about the nature of the illness itself. And unbeknownst to the Galvins, samples of their DNA informed decades of genetic research that continues today, offering paths to treatment, prediction, and even eradication of the disease for future generations. With clarity and compassion, bestselling and award-winning author Robert Kolker uncovers one family's unforgettable legacy of suffering, love, and hope.

Affective and Schizoaffective Disorders

Affective and Schizoaffective Disorders PDF Author: Andreas Marneros
Publisher: Springer Science & Business Media
ISBN: 3642753531
Category : Medical
Languages : en
Pages : 306

Book Description
Several contributions in our first book about schizo affective disorders (Marneros and Tsuang, Schizoaffective Psychoses, Springer-Verlag, 1986) supported the assumption that schizoaffective disorders differ in relevant ways from schizophrenic disorders. The classification of schizo affective disorders as a subgroup of schizophrenia has also been criticized, and empirical research in clinical, genetic, therapeutic, and prognostic areas supports the idea that there are some strong similari ties between schizo affective and affective disorders. Of course, there are not only similarities between these two groups, but also differences just as there are between schizo affective and schizophrenic disorders. It is precisely the existence of similarities and differences between schizo affective disorders and the other two so-called typical mental disorders, i.e., schizophrenia and affective disorders, which makes them a challenge in psychiatric research, a challenge to the traditional dichotomy in the classification of disorders which originated with Kraepelin. This challenge is certainly proving fruitful in psychiatric research. These "cases in between" may well demonstrate that sep arating, dividing, and limiting is not always meaningful. Sometimes it can be more meaningful to unify; to unify in the sense of building bridges between typical groups. It is here that the assumption of a "psychotic continuum" can become relevant, and the investigation of schizoaffective disorders is of prime importance in research on a possible continuum of psychosis.

Curing Bipolar Disorder and Schizophrenia

Curing Bipolar Disorder and Schizophrenia PDF Author: Doris Denise King
Publisher:
ISBN: 9780982485309
Category : Psychology
Languages : en
Pages : 104

Book Description
Based on the work and research of the late Dr. John Lee, "Curing Bipolar Disorder and Schizophrenia" explains the importance of hormone balance to mental health and describes what can happen in the brain and body when they don't have the progesterone they need.

Bipolar Disorder

Bipolar Disorder PDF Author: Lucy Hilts
Publisher: Self Publisher
ISBN: 8835876532
Category : Psychology
Languages : en
Pages : 41

Book Description
Does bipolar disorder occur in children? What are some of the main elements of a bipolar disorder? What is so difficult about diagnosing bipolar disorder? What are possible solutions? These and many other questions will be answered in this book. Aside from this, clinical concepts will be discussed, as well as nutritional resources, the connection to autism, suicidal tendencies, and the overlap of the symptoms in schizophrenia. In short, if you’re trying to learn more about bipolar disorder, this book is a good choice.

The Natural History of Mania, Depression, and Schizophrenia

The Natural History of Mania, Depression, and Schizophrenia PDF Author: George Winokur
Publisher: American Psychiatric Pub
ISBN: 9780880487269
Category : Medical
Languages : en
Pages : 396

Book Description
The Natural History of Mania, Depression, and Schizophrenia takes an unusual look at the course of mental illness, based on data from the Iowa 500 Research Project. This project involved the long-term (30-40 years) follow-up of patients diagnosed with schizophrenia, depression, and bipolar illness. After presenting a history and background of the study, the authors provide fascinating, verbatim interviews with patients at the time of hospital admission in the 1930s and 1940s. Eight of the 15 chapters are dedicated to the modern, systematic follow-up and family study of these patients. Medical students, residents, psychiatrists, social workers, psychologists, ministers, and clinicians are offered an interesting look at what might be expected should treatment not be instituted with such patients. Unlike earlier works that focused on the descriptive aspects of mental illness, this book provides clinicians with a more systematic evaluation of the symptom picture, course and outcome, and family history. It concludes with useful information on the diagnosis and classification of the affective disorders and chronic nonaffective psychoses.

Schizophrenia Is a Misdiagnosis

Schizophrenia Is a Misdiagnosis PDF Author: C. Raymond Lake
Publisher: Springer Science & Business Media
ISBN: 1461418704
Category : Medical
Languages : en
Pages : 442

Book Description
Schizophrenia is the most widely known and feared mental illness worldwide, yet a rapidly growing literature from a broad spectrum of basic and clinical disciplines, especially epidemiology and molecular genetics, suggests that schizophrenia is the same condition as a psychotic bipolar disorder and does not exist as a separate disease. The goal is to document and interpret these data to justify eliminating the diagnosis of schizophrenia from the nomenclature. The author reviews the changing diagnostic concepts of schizophrenia and bipolar disorder with a historical perspective to clarify how the current conflict over explanations for psychosis has arisen. That two disorders, schizophrenia and bipolar, known as the Kraepelinian dichotomy, account for the functional psychoses has been a cornerstone of Psychiatry for over 100 years, but is questioned because of substantial similarities and overlap between these two disorders. Literature in the field demonstrates that psychotic patients are frequently misdiagnosed as suffering from the disease called schizophrenia when they suffer from a psychotic mood disorder. Such patients, their families, and their caretakers suffer significant disadvantages from the misdiagnosis. Psychotic patients misdiagnosed with schizophrenia receive substandard care regarding their medications, thus allowing their bipolar conditions to worsen. Other adverse effects are substantial and will be included. Liability for medical malpractice is of critical importance for the mental health professionals who make the majority of the diagnoses of schizophrenia. The concept put forward in this work will have a discipline-altering impact.