Safety and Efficacy of Sustained-release Recombinantly Derived Bovine Somatotropin Administered to Lactating Dairy Cows PDF Download

Author: Richard Alan Larson
Publisher:
ISBN:
Category : Controlled release preparations
Languages : en
Pages : 264

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Author: United States. General Accounting Office
Publisher:
ISBN:
Category : Beef
Languages : en
Pages : 72

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Author: Rolf James Annexstad
Publisher:
ISBN:
Category :
Languages : en
Pages : 206

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Author: Khaled Gohary
Publisher:
ISBN:
Category :
Languages : en
Pages :

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This thesis describes an evaluation of the impact of administering recombinant bovine somatotropin (rbST) before calving on health, milk production, reproductive performance and dry matter intake (DMI) of lactating dairy cows. In addition, this thesis includes an evaluation of the cost of subclinical ketosis (SCK), economic value of using Rumensin® Controlled Release Capsules (CRC) for disease prevention and the economic value of using propylene glycol (PG) for treatment of SCK after being diagnosed with different cow-side tests. One randomized clinical trial was conducted on 4 commercial dairy herds in Southern Ontario and at the University of Guelph where rbST was administered every other week starting at 28-22 days before calving until cows calved. The key finding of this study was that pre-partum rbST administration had no significant clinical impact on health and performance of dairy cows after calving. A spreadsheet was constructed to perform the economic analysis of ketosis cost and treatment. It was estimated that one case of SCK can cost up to $350. The economic value of using CRC to reduce ketosis depends on the prevalence of ketosis-related diseases in a herd. Using a cow-side test with high sensitivity and specificity to diagnose SCK pays off through minimizing the losses by classifying fewer cows as false negatives and therefore treating more sick cows and mitigating the negative impact of SCK. Results presented in this thesis highlight the insufficiency of rbST administration in the pre-partum period only, to improve health in the transition period and to improve cow performance after calving. Results of an economic analysis highlight the high cost impact of SCK and the importance of reducing its incidence through implementing management during the transition period.

Author: National Research Council
Publisher: National Academies Press
ISBN: 0309084393
Category : Technology & Engineering
Languages : en
Pages : 201

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Genetic-based animal biotechnology has produced new food and pharmaceutical products and promises many more advances to benefit humankind. These exciting prospects are accompanied by considerable unease, however, about matters such as safety and ethics. This book identifies science-based and policy-related concerns about animal biotechnologyâ€"key issues that must be resolved before the new breakthroughs can reach their potential. The book includes a short history of the field and provides understandable definitions of terms like cloning. Looking at technologies on the near horizon, the authors discuss what we know and what we fear about their effectsâ€"the inadvertent release of dangerous microorganisms, the safety of products derived from biotechnology, the impact of genetically engineered animals on their environment. In addition to these concerns, the book explores animal welfare concerns, and our societal and institutional capacity to manage and regulate the technology and its products. This accessible volume will be important to everyone interested in the implications of the use of animal biotechnology.

Author: National Research Council
Publisher: National Academies
ISBN: 0309049970
Category : Technology & Engineering
Languages : en
Pages : 94

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In the past decade, animal scientists have learned that administering recombinantly derived somatotropin (growth hormone) to cows improves milk production and that giving beta-adrenergic agonists to meat animals improves productivity and leanness. In order for these metabolic modifiers to yield benefits, however, sound management of the animals' nutrition is necessary. This volume reports on how these substances work in the animals' metabolism, what effects they might have on nutrient requirements of domestic livestock, and what information should be developed further by investigators. The book explores the current understanding of the biology, structure, mechanisms of action, and treatment effects of somatotropin, beta-adrenergic agonists, and anabolic steroids. A companion volume to the Nutrient Requirements of Domestic Animals series, this authoritative volume will be required reading for animal scientists, researchers, veterinarians, livestock farmers, and faculty and students in university animal veterinary science programs.

Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 796

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Author: National Research Council
Publisher: National Academies Press
ISBN: 0309175771
Category : Medical
Languages : en
Pages : 276

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The use of drugs in food animal production has resulted in benefits throughout the food industry; however, their use has also raised public health safety concerns. The Use of Drugs in Food Animals provides an overview of why and how drugs are used in the major food-producing animal industriesâ€"poultry, dairy, beef, swine, and aquaculture. The volume discusses the prevalence of human pathogens in foods of animal origin. It also addresses the transfer of resistance in animal microbes to human pathogens and the resulting risk of human disease. The committee offers analysis and insight into these areas: Monitoring of drug residues. The book provides a brief overview of how the FDA and USDA monitor drug residues in foods of animal origin and describes quality assurance programs initiated by the poultry, dairy, beef, and swine industries. Antibiotic resistance. The committee reports what is known about this controversial problem and its potential effect on human health. The volume also looks at how drug use may be minimized with new approaches in genetics, nutrition, and animal management.

Author:
Publisher: Academic Press
ISBN: 0123744075
Category : Technology & Engineering
Languages : en
Pages : 4072

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Dairy Science, Four Volume Set includes the study of milk and milk-derived food products, examining the biological, chemical, physical, and microbiological aspects of milk itself as well as the technological (processing) aspects of the transformation of milk into its various consumer products, including beverages, fermented products, concentrated and dried products, butter and ice cream. This new edition includes information on the possible impact of genetic modification of dairy animals, safety concerns of raw milk and raw milk products, peptides in milk, dairy-based allergies, packaging and shelf-life and other topics of importance and interest to those in dairy research and industry. Fully reviewed, revised and updated with the latest developments in Dairy Science Full color inserts in each volume illustrate key concepts Extended index for easily locating information

Author: National Research Council
Publisher: National Academies Press
ISBN: 0309166152
Category : Science
Languages : en
Pages : 254

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Book Description
Assists policymakers in evaluating the appropriate scientific methods for detecting unintended changes in food and assessing the potential for adverse health effects from genetically modified products. In this book, the committee recommended that greater scrutiny should be given to foods containing new compounds or unusual amounts of naturally occurring substances, regardless of the method used to create them. The book offers a framework to guide federal agencies in selecting the route of safety assessment. It identifies and recommends several pre- and post-market approaches to guide the assessment of unintended compositional changes that could result from genetically modified foods and research avenues to fill the knowledge gaps.