Role of Nutrigenomics in Modern-day Healthcare and Drug Discovery PDF Download

Author: Genevieve Dable-Tupas
Publisher: Elsevier
ISBN: 0323859623
Category : Science
Languages : en
Pages : 598

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Book Description
Role of Nutrigenomics in Modern-day Healthcare and Drug Discovery presents novel insights into how these tools can be applied in the study of nutrient-gene interaction for the management of certain disease conditions without using synthetic drugs or other treatments that come with side effects. Divided into three parts, Part I presents chapters that give background information of the subject while laying a framework for other chapters to follow. Part II presents chapters that discuss the role of nutrigenomics in healthcare, while Part III presents chapters that discuss the role of nutrigenomics in modern day drug discovery. Written by a global team of experts from key institutions around the world, this book is useful for drug developers, medicinal chemists, public health scientists, molecular biologists, biochemists, toxicologists and food scientists. - Provides readers with background information on the role of nutrigenomics in healthcare, with a focus on emerging topics in nutrigenetics and nutrigenomics - Presents chapters that discusses the role of nutrigenomics in the modern day drug discovery for the treatment and management of diseases - Includes a wide array of definitions, methods, summaries, figures and tables to aid readers with understanding and application

Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309477670
Category : Medical
Languages : en
Pages : 155

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Book Description
On December 5, 2017, the National Academies of Sciences, Engineering, and Medicine hosted a public workshop titled Nutrigenomics and the Future of Nutrition in Washington, DC, to review current knowledge in the field of nutrigenomics as it relates to nutrition. Workshop participants explored the influence of genetic and epigenetic expression on nutritional status and the potential impact of personalized nutrition on health maintenance and chronic disease prevention. This publication summarizes the presentations and discussions from the workshop.

Author: David Castle
Publisher: Academic Press
ISBN: 0080920829
Category : Technology & Engineering
Languages : en
Pages : 311

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Book Description
Nutrigenomics is the rapidly developing field of science that studies nutrient-gene interaction. This field has broad implications for understanding the interaction of human genomics and nutrition, but can also have very specific implications for individual dietary recommendations in light of personal genetics. Predicted applications for nutrigenomics include genomics-based dietary guidelines and personalized nutrition based on individual genetic tests. These developments have sweeping ethical, legal and regulatory implications for individuals, corporations and governments.This book brings together experts in ethics, law, regulatory analysis, and communication studies to identify and address relevant issues in the emerging field of nutritional genomics. Contributing authors are experts in the social aspects of biotechnology innovation, with expertise in nutrigenomics. From addressing the concern that nutrigenomics will transform food into medicine and undermine pleasures associated with eating to the latest in the science of nutrigenomics, this book provides a world-wide perspective on the potential impact of nutrigenomics on our association with food. - Explores the rapidly developing, yet not fully understood, impact of nutrigenomics on the relationship to food medicalization, genetic privacy, nutrition and health - Provides ground for further exploration to identify issues and provide analysis to aid in policy and regulation development - Provides ethical and legal insights into this unfolding science, as well as serving as a model for thinking about issues arising in other fields of science and technology

Author: Artemis P. Simopoulos
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805594275
Category : Medical
Languages : en
Pages : 201

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Book Description
Awareness of the influence of our genetic variation to dietary response (nutrigenetics) and how nutrients may affect gene expression (nutrigenomics) is prompting a revolution in the field of nutrition. Nutrigenetics/Nutrigenomics provide powerful approaches to unravel the complex relationships among nutritional molecules, genetic variants and the biological system. This publication contains selected papers from the '3rd Congress of the International Society of Nutrigenetics/Nutrigenomics' held in Bethesda, Md., in October 2009. The contributions address frontiers in nutrigenetics, nutrigenomics, epigenetics, transcriptomics as well as non-coding RNAs and posttranslational gene regulations in various diseases and conditions. In addition to scientific studies, the challenges and opportunities facing governments, academia and the industry are included. Everyone interested in the future of personalized medicine and nutrition or agriculture, as well as researchers in academia, government and industry will find this publication of the utmost interest for their work.

Author: Arturo Panduro
Publisher: Frontiers Media SA
ISBN: 2832551092
Category : Medical
Languages : en
Pages : 104

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Book Description
Human populations that have recently undergone substantial changes in their traditional social, cultural, and dietary habits have shown an increased susceptibility to developing chronic diet-related diseases concerning their genetic background. One factor is that the population's adaptive genetic variants related to its evolutionary history are exposed to different physical and lifestyle environments that underlie and influence the current patterns of disease risk. Under this perspective, the current obesogenic environment has promoted the acculturation of a westernized diet disrupting the ancestral gene-foods/nutrients/bioactive compounds interactions, i.e., ancestral genetic/ethnic profile vs. modern lifestyle. Modern lifestyles, including unhealthy dietary patterns, have further impaired the consumption of staple foods with essential nutrients and functional properties, increasing the incidence of obesity and associated comorbidities. However, most conventional nutrition approaches targeting chronic diseases have limited impact on managing the leading non-communicable diseases affecting modern societies.

Author: Genevieve Dable-Tupas
Publisher: Elsevier
ISBN: 0443154368
Category : Medical
Languages : en
Pages : 385

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Book Description
Human Microbiome Drug Targets: Modern Approaches in Disease Management presents fundamental information on the human microbiome, looking into the relationship between the microbiome and how it changes with specific diseases. Delving into the multifaceted roles of the microbiome in health and disease, the book's chapters discuss the role of the human microbiome in the pathophysiologic understanding of relevant diseases or disorders and their management. As changes in the human microbiome can provide clues to the probable cause and effect of diseases or disorders, as well as the impacts of therapy or intervention, this book is a welcomed addition to the existing research. Explaining how a better understanding of the microbiome and its impact on health and disease can pave the way for future discoveries leading to better health outcomes, this book will be of interest to drug developers, medicinal chemists, microbiologists, infectious disease specialists, biochemists, and students. - Provides readers with background information on the human microbiome, its evolution, and current understanding - Includes chapters dedicated to the importance of the human microbiome as "drugs" and as drug targets - Serves as a guide to drug developers working in pharma, biotech, and academia, bringing together the latest research on the topic

Author: John Oloche Onuh
Publisher: CRC Press
ISBN: 1000935876
Category : Medical
Languages : en
Pages : 645

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Book Description
Phytochemicals are receiving increasing attention due to their observed nutritional and health-promoting effects in numerous food applications. As plant secondary metabolites with bioactive properties, they may provide desirable health benefits beyond basic nutrition to reduce chronic disease conditions. Their importance in nutrition and health cannot be overstated as it has generated so much interest and studies focused on elucidating their roles has produced so many outstanding results. Plant phytochemicals are readily used in alternative medicine in South East Asia especially, in China and India and they are becoming widely acceptable worldwide. However, very little is still known about the phytochemicals despite these intense research efforts because of their diverse biological and chemical nature. In this newest addition to the series, Nutraceuticals: Basic Research and Clinical Applications, Plant Food Phytochemicals and Bioactive Compounds in Nutrition and Health provides a comprehensive review of the current state of knowledge in the field of bioactive plant phytochemical compounds, their food sources, bioactivities, bioavailability, extraction, production, and applications. Experts in the field discuss various bioactivities of the notable and promising plant phytochemicals of significance in nutrition and health, e.g., lowering of CVD, hypertension, cholesterol, diabetes, obesity, inflammation, cancer, oxidative stress, neurodegenerative diseases and a host of other chronic disease conditions. Key Features: Describes the various nutritional and bioactive significances of notable and promising plant phytochemicals of significance in nutritional and medical research and their food and/or plant sources Includes various approaches for the quantification, extraction and production of the notable and promising phytochemical compounds in nutrition and health Examines the challenges and promises of plant phytochemical as ingredients for the development of functional foods and nutraceuticals as well as their use in alternative medicine Discusses regulatory issues regarding plant phytochemicals, especially as it pertains to their health claims and use

Author: R. C. Sobti
Publisher: Springer Nature
ISBN: 9819962633
Category :
Languages : en
Pages : 1584

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Book Description

Author: Amal Kumar Dhara
Publisher: Springer Nature
ISBN: 9819977037
Category :
Languages : en
Pages : 637

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Book Description

Author: Mithun Rudrapal
Publisher: John Wiley & Sons
ISBN: 1394188838
Category : Science
Languages : en
Pages : 405

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Book Description
Polyphenols Understand polyphenols and their benefits with this comprehensive overview Polyphenols are a group of beneficial compounds—including phenolic acids, flavonoids, anthocyanins, and others—that can be found in a vast range of plants and plant-based foods. Their health benefits and the variety of their applications in functional foods, dietary supplements, and similar areas have made polyphenols a $1 billion market, a figure that is expected to more than double in the next decade. This has placed increased emphasis on areas of cutting-edge research such as the use of bio-based nanodelivery systems to improve the oral bioavailability of polyphenols. Polyphenols constitutes a comprehensive introduction to these compounds, their health benefits, and their potential nutraceutical applications. It incorporates both the biochemical fundamentals of polyphenols and their precise potential to prevent numerous common diseases. The result is an essential reference for a vital, growing area of research and industry. Polyphenols readers will also find: Detailed coverage of polyphenols’ occurrence, bioactivity, and technological applications In-depth discussion of nano-based delivery systems to increase polyphenols’ therapeutic efficacy and oral bioavailability and to reduce required dosages Guidance for developing treatments for cancers, cardiovascular diseases, inflammatory conditions, and more Polyphenols is ideal for food scientists and manufacturers, medicinal chemists, pharmaceutical scientists, and any biochemical or biomedical researcher or professional working with polyphenols or plant-based foods.