Risk of Subsequent Adjacent Fractures after Vertebral Augmentation in the Treatment for Osteoporotic Vertebral Compression Fractures PDF Download

Author: José Manuel Ortega Zufiría
Publisher: GRIN Verlag
ISBN: 3346289052
Category : Medical
Languages : en
Pages : 25

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Book Description
Research Paper (postgraduate) from the year 2020 in the subject Medicine - Other, grade: 10.00, , course: NEUROCIRUGÍA, language: English, abstract: The aim of this study was to investigate whether percutaneous vertebral augmentation (PVA) was associated with clinical and radiological subsequent adjacent fractures. A systematic review and meta-analysis was performed searching on PubMed, EMBASE, Cochrane library, Google Scholar, web of science and ClinicalTrial.gov from the establishment of the database to January 2020. Eligible studies assessing the subsequent adjacent fractures after PVA compared with conservative treatment (CT) were incorporated. The pooled risk ratio (RR) with its 95% confidence intervals (95% CI) was used. Heterogeneity, sensitivity and publication bias analyses were performed. A total of 24 studies were considered eligible and were included finally. 20/421 patients (4.75%) had clinical subsequent adjacent fractures from PVA group, and 25/359 patients (6.96%) had from CT group, and 46/440 patients (10.45%) from PVA group and 36/444 patients (8.10%) from CT group had radiological subsequent adjacent fractures. There both had no significant difference between two groups (RR=0.67, 95%CI: [0.38, 1.19], P = 0.17)/ (RR=1.13, 95%CI: [0.75, 1.70], P = 0.576). However, in fractured vertebrae, number in PVA group was more than that in CT group (RR=1.41, 95%CI: [1.03, 1.93], P = 0.03). Collectively, currently available literature provides data showed PVA did not increase the incidence for subsequent adjacent fractures, no matter it was clinical or radiological fracture. But PVA may increase the number of fractured vertebrae.

Author: Stephan Becker
Publisher: Springer Science & Business Media
ISBN: 3211742212
Category : Medical
Languages : en
Pages : 169

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Book Description
This is the first book to cover minimal-invasive treatment of osteoporotic, tumorous and traumatic vertebral fractures in the English language. In addition to detailed descriptions of the techniques, including tips and tricks from experts, the book contains a chapter about the medical treatment of osteoporosis, which is indispensable in the interdisciplinary approach to osteoporosis. This acclaimed innovative concept unites several treatment aspects. More conservative treatment methods are also presented in this work. All chapters reflect new developments and clinical findings in the field of orthopaedics, surgery, traumatology and neurosurgery.

Author: John M. Mathis
Publisher: Springer Science & Business Media
ISBN: 0387360832
Category : Medical
Languages : en
Pages : 316

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Book Description
Since the ?rst edition of this book was published in 2002, there have been many advances in our knowledge of percutaneous vertoplasty (PV), particularly about how to perform the procedure more safely and how to approach more complex case situations. Additionally, mate- als that were initially used “off label” or that simply were not FDA approved have completed their governmental review and have received FDA approval. This has increased the legitimacy of the p- cedure from the legal and reimbursement perspective. Controversy over height restoration and device selection has become a progressively bigger issue over time. Kyphoplasty (balloon assisted vertebroplasty) has received tremendous emphasis. This book c- pares and contrasts data and claims that differentiate kyphoplasty from percutaneous vertebroplasty. We also look at other methods that pot- tially can be used for height restoration. New procedures that deal with bone augmentation in other anatomic regions have evolved (i.e., sacroplasty) and are discussed. As this re- lution in image-guided percutaneous bone augmentation has dev- oped, multiple medical specialties have embraced these procedures in their training programs for both residents and practicing physicians.

Author: Afshin E. Razi
Publisher: Springer Nature
ISBN: 3030338614
Category : Medical
Languages : en
Pages : 233

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Book Description
Vertebral compression fractures (VCFs) are the most common type of fracture secondary to osteoporosis. These fractures are associated with significant rates of morbidity and mortality and annual direct medical expenditures of more than $1 billion in the United States. This book presents a concise review of the diagnosis, management and treatment of vertebral compression fractures, discussing best practices for evaluation and radiographic diagnosis of vertebral compression fractures, as well as both non-operative and operative treatment options, including cement augmentation. Opening chapters discuss both normal bone physiology as well as the pathophysiology of osteoporotic bone, and the evaluation and biomechanics of VCF, both osteoporotic and pathologic. Examination, radiography and long-term sequelae of VCF are then presented. The bulk of the remainder of the book focuses on medical, non-operative and operative management strategies, including vertebroplasty and kyphoplasty cement augmentation, management of spinal deformity, VCF adjacent to previous spinal fusion, and sacral insufficiency fractures. A final chapter on future treatment strategies rounds out the presentation. Spinal Compression Fractures in Osteoporotic and Pathologic Bone is ideal for orthopaedic trauma, spine, and neurosurgeons. The book is also intended for endocrinologists, rheumatologists, interventional radiologists, physiatrists, anesthesiologists, primary care physicians, and other practitioners who manage and treat patients with osteoporosis.

Author: Daniel K. Resnick
Publisher: Thieme
ISBN: 163853196X
Category : Medical
Languages : en
Pages : 168

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Book Description
Largely due to their capacity to provide immediate pain relief in osteoporotic compression fractures and neoplastic disease of the spine, vertebroplasty and kyphoplasty have become popular techniques in recent years. These procedures require minimal incisions and can be performed without general anesthesia, which adds to their appeal. This is the first book to cover everything that is currently known about vertebroplasty and kyphoplasty, including patient selection, operative techniques, complication avoidance, management, outcomes, and more! You will find extensive discussions of the role of vertebroplasty and kyphoplasty in acute fractures, non-osteoporotic pathological compression fractures, and burst fractures. A multidisciplinary panel of spine surgeons, orthopedic surgeons, neurosurgeons, and interventional radiologists provide their unique perspectives, along with comparisons of techniques and potential complications to help you select the right procedure for a particular patient. Filling a significant gap in literature, this exceptional work provides a ''snapshot'' of these modern surgical techniques, with practical guidelines on using them to provide optimal patient care. It is a state-of-the-art resource for all informed spine surgeons, radiologists, and neurosurgeons. *Message from AANS and Thieme: Participants using this book to apply for CME credit now have until January 31, 2010 to complete and pass the Home Study Examination (available online from the AANS - see CME Credit Information page for more information). (A co-publication of Thieme and the American Association of Neurological Surgeons)

Author: Kathryn Fitch
Publisher: Rand Corporation
ISBN: 9780833029188
Category : History
Languages : en
Pages : 109

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Book Description
Health systems should function in such a way that the amount of inappropriate care is minimized, while at the same time stinting as little as possible on appropriate and necessary care. The ability to determine and identify which care is overused and which is underused is essential to this functioning. To this end, the "RAND/UCLA Appropriateness Method" was developed in the 1980s. It has been further developed and refined in North America and, increasingly, in Europe. The rationale behind the method is that randomized clinical trials--the "gold standard" for evidence-based medicine--are generally either not available or cannot provide evidence at a level of detail sufficient to apply to the wide range of patients seen in everyday clinical practice. Although robust scientific evidence about the benefits of many procedures is lacking, physicians must nonetheless make decisions every day about when to use them. Consequently, a method was developed that combined the best available scientific evidence with the collective judgment of experts to yield a statement regarding the appropriateness of performing a procedure at the level of patient-specific symptoms, medical history, and test results. This manual presents step-by-step guidelines for conceptualising, designing, and carrying out a study of the appropriateness of medical or surgical procedures (for either diagnosis or treatment) using the RAND/UCLA Appropriateness Method. The manual distills the experience of many researchers in North America and Europe and presents current (as of the year 2000) thinking on the subject. Although the manual is self-contained and complete, the authors do not recommend that those unfamiliar with the RAND/UCLA Appropriateness Method independently conduct an appropriateness study; instead, they suggest "seeing one" before "doing one." To this end, contact information is provided to assist potential users of the method.

Author: Stephan Grampp
Publisher: Springer Science & Business Media
ISBN: 3662052350
Category : Medical
Languages : en
Pages : 204

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Book Description
Due to the aging population in the Western world, osteoporosis has become a major problem which is of interest to several medical disciplines: not only radiologists but also gynecologists, endocrinologists, rheumatologists, and orthopedic surgeons are involved in the management of this widespread condition. Functional imaging is becoming rapidly an important area of diagnostic radiology. Imaging of osteoporosis is another application of this recent addition to the armory of radiology. It is important that radiologists should be fully aware of the range of diagnostic modalities-conventional radiologic methods, dual X-ray absorptiometry, quantitative computed tomography, quantitative ultrasound, magnetic resonance imaging, etc. -that are now available for the diagnosis and the follow-up of osteoporosis, and know how to apply these sophisticated methods in daily clinical practice. Dr. S. Grampp is a radiologist with a longstanding interest in osteoporosis, and his previous publications on this condition are internationally known. He has been very successful in engaging several outstandingly qualified experts to contribute to the indi vidual chapters of this superb book, which provides a omprehensive c overview of our current knowledge of osteoporosis. I am confident that this volume will meet with great interest from radiologists and all other clinicians involved in the care of patients with osteoporosis and will encounter the same success as many previous volumes in this series.

Author: WHO Scientific Group on Prevention and Management of Osteoporosis
Publisher: World Health Organization
ISBN: 9241209216
Category : Medical
Languages : en
Pages : 206

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Book Description
Bone is hard tissue that is in a constant state of flux being built up by bone-forming cells called osteoblasts while also being broken down or resorbed by cells known as osteoclasts. During childhood and adolescence bone formation is dominant; bone length and girth increase with age ending at early adulthood when peak bone mass is attained. Males generally exhibit a longer growth period resulting in bones of greater size and overall strength. In males after the age of 20 bone resorbtion becomes predominant and bone mineral content declines about 4% per decade. Females tend to maintain peak mineral content until menopause at which time it declines about 15% per decade. Osteoporosis is a disease characterized by low bone mass and structural deterioration of bone tissue leading to bone fragility and an increased susceptibility to fractures especially of the hip spine and wrist. Osteoporosis occurs primarily as a result of normal ageing but can arise as a result of impaired development of peak bone mass (e.g. due to delayed puberty or undernutrition) or excessive bone loss during adulthood (e.g. due to estrogen deficiency in women undernutrition or corticosteriod use). Osteoporosis-induced fractures cause a great burden to society. Hip fractures are the most serious as they nearly always result in hospitalization are fatal about 20% of the time and produce permanent disability about half the time. Fracture rates increase rapidly with age and the lifetime risk of fracture in 50 year-old women is about 40% similar to that for coronary heart disease. In 1990 there were 1.7 million hip fractures alone worldwide; with changes in population demographics this figure is expected to rise to 6 million by 2050. To help describe the nature and consequences of osteoporosis as well as strategies for its prevention and management a WHO Scientific Group meeting of international experts was held in Geneva which resulted in this technical report. This monograph describes in detail normal bone development and the causes and risk factors for developing osteoporosis. The burden of osteoporosis is characterized in terms of mortality morbidity and economic costs. Methods for its prevention and treatment are discussed in detail for both pharmacological and non-pharmacological approaches. For each approach the strength of the scientific evidence is listed. The report also provides cost-analysis information for potential interventions and discusses important aspects of developing national policies to deal with osteoporosis. Recommendations are made to the general population care providers health administrators and researchers. Lastly national organizations and support groups are listed by country.

Author: Max Aebi
Publisher: Springer Science & Business Media
ISBN: 9783540244080
Category : Medical
Languages : en
Pages : 154

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Book Description
The "Bone and Joint Decade" draws our attention with increased intensity to the problem of the changes related to aging of our musculoskeletal system and the associated socioeconomic implications. In view of the increasing age of the worldwide population the impact seems to be tremendous. The editors of The Aging Spine pick up this interesting topic and engage opinion leaders to contribute their knowledge in this supplement. The various contributions cover most of the important problems, which are included in the vast specter of aging spine: osteoporosis, spinal stenosis, and tumors of the spine. The aging spine will be an everpresent issue in the life of a physician taking care of the different pathologies of the spine. This text will help to better understand the nature of the different changes in the spine of the elderly. It contributes to enabling us to diagnose and to treat this complex problem in an appropriate way.

Author: Adnan I. Qureshi
Publisher: Cambridge University Press
ISBN: 1139500740
Category : Medical
Languages : en
Pages : 515

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Book Description
Endovascular intervention - using medication and devices introduced through catheters or microcatheters placed into the blood vessels through a percutaneous approach - has emerged as a relatively new minimally invasive approach to treat cerebrovascular disease and possibly intracranial neoplasms. This textbook provides a comprehensive review of principles pertinent to endovascular treatment of cerebrovascular diseases and intracranial tumors, with a detailed description of techniques for these procedures and periprocedural management strategies. Particular emphasis is placed on expert interpretation of the quality of evidence provided and implications for practice related to endovascular procedures. This will be essential reading for clinicians working in interventional neurology and cardiology, endovascular neurosurgery, vascular surgery and neuroradiology.