Author: Marek Malik
Publisher: Frontiers Media SA
ISBN: 288966970X
Category : Science
Languages : en
Pages : 269
Book Description
Effective identification of patients at increased risk of malignant cardiac arrhythmia presently represents a clinically important unmet need. Existing guidelines for the selection of candidates for the prophylactic implantation of cardioverters-defibrillators (ICD) are based solely on the reduction of ventricular haemodynamic performance. Although this guidance is based on statistical results of previously conducted randomized clinical trials, available experience shows that it does not serve clinical needs efficiently. The majority of patients who are implanted with ICDs for prophylactic reasons never utilize the device during its technical longevity whilst, at the same time, many patients who succumb to sudden cardiac death do not have ventricular haemodynamic performance particularly compromised. Recent results also showed that the previous statistical findings of ICD efficacy are not fully reproducible in patients with non-ischemic heart disease and that the reduction of sudden cardiac death after myocardial infarction by external automatic defibrillation vests is lower than expected. Advances in cardiac electrophysiology are needed for better understanding of the mechanisms that are the basis of different arrhythmic abnormalities. Increased understanding of these mechanisms will allow them to be more effectively classified so that optimum therapeutic options can be offered. Likewise, better understanding of the underlying electrophysiology processes is needed so that novel and more focused randomized clinical trials can be designed. Compared to invasive electrophysiological studies, noninvasive cardiac electrophysiology offers the possibility of screening larger number of patients as well as healthy subjects investigated under different provocations and conditions. To advance the field, broad spectrum of studies is needed together with meta-analyses and reviews facilitating research interactions.
Risk Factors of Noninvasive Cardiac Electrophysiology
Author: Marek Malik
Publisher: Frontiers Media SA
ISBN: 288966970X
Category : Science
Languages : en
Pages : 269
Book Description
Effective identification of patients at increased risk of malignant cardiac arrhythmia presently represents a clinically important unmet need. Existing guidelines for the selection of candidates for the prophylactic implantation of cardioverters-defibrillators (ICD) are based solely on the reduction of ventricular haemodynamic performance. Although this guidance is based on statistical results of previously conducted randomized clinical trials, available experience shows that it does not serve clinical needs efficiently. The majority of patients who are implanted with ICDs for prophylactic reasons never utilize the device during its technical longevity whilst, at the same time, many patients who succumb to sudden cardiac death do not have ventricular haemodynamic performance particularly compromised. Recent results also showed that the previous statistical findings of ICD efficacy are not fully reproducible in patients with non-ischemic heart disease and that the reduction of sudden cardiac death after myocardial infarction by external automatic defibrillation vests is lower than expected. Advances in cardiac electrophysiology are needed for better understanding of the mechanisms that are the basis of different arrhythmic abnormalities. Increased understanding of these mechanisms will allow them to be more effectively classified so that optimum therapeutic options can be offered. Likewise, better understanding of the underlying electrophysiology processes is needed so that novel and more focused randomized clinical trials can be designed. Compared to invasive electrophysiological studies, noninvasive cardiac electrophysiology offers the possibility of screening larger number of patients as well as healthy subjects investigated under different provocations and conditions. To advance the field, broad spectrum of studies is needed together with meta-analyses and reviews facilitating research interactions.
Publisher: Frontiers Media SA
ISBN: 288966970X
Category : Science
Languages : en
Pages : 269
Book Description
Effective identification of patients at increased risk of malignant cardiac arrhythmia presently represents a clinically important unmet need. Existing guidelines for the selection of candidates for the prophylactic implantation of cardioverters-defibrillators (ICD) are based solely on the reduction of ventricular haemodynamic performance. Although this guidance is based on statistical results of previously conducted randomized clinical trials, available experience shows that it does not serve clinical needs efficiently. The majority of patients who are implanted with ICDs for prophylactic reasons never utilize the device during its technical longevity whilst, at the same time, many patients who succumb to sudden cardiac death do not have ventricular haemodynamic performance particularly compromised. Recent results also showed that the previous statistical findings of ICD efficacy are not fully reproducible in patients with non-ischemic heart disease and that the reduction of sudden cardiac death after myocardial infarction by external automatic defibrillation vests is lower than expected. Advances in cardiac electrophysiology are needed for better understanding of the mechanisms that are the basis of different arrhythmic abnormalities. Increased understanding of these mechanisms will allow them to be more effectively classified so that optimum therapeutic options can be offered. Likewise, better understanding of the underlying electrophysiology processes is needed so that novel and more focused randomized clinical trials can be designed. Compared to invasive electrophysiological studies, noninvasive cardiac electrophysiology offers the possibility of screening larger number of patients as well as healthy subjects investigated under different provocations and conditions. To advance the field, broad spectrum of studies is needed together with meta-analyses and reviews facilitating research interactions.
Cardiovascular Disability
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 030915698X
Category : Medical
Languages : en
Pages : 304
Book Description
The Social Security Administration (SSA) uses a screening tool called the Listing of Impairments to identify claimants who are so severely impaired that they cannot work at all and thus immediately qualify for benefits. In this report, the IOM makes several recommendations for improving SSA's capacity to determine disability benefits more quickly and efficiently using the Listings.
Publisher: National Academies Press
ISBN: 030915698X
Category : Medical
Languages : en
Pages : 304
Book Description
The Social Security Administration (SSA) uses a screening tool called the Listing of Impairments to identify claimants who are so severely impaired that they cannot work at all and thus immediately qualify for benefits. In this report, the IOM makes several recommendations for improving SSA's capacity to determine disability benefits more quickly and efficiently using the Listings.
Diagnosis and Management of Hypertrophic Cardiomyopathy
Author: Barry J. Maron
Publisher: John Wiley & Sons
ISBN: 140514615X
Category : Medical
Languages : en
Pages : 527
Book Description
Diagnosis and Management of Hypertrophic Cardiomyopathy is aunique, multi-authored compendium of information regarding thecomplexities of clinical and genetic diagnosis, natural history,and management of hypertrophic cardiomyopathy (HCM)—the mostcommon and important of the genetic cardiovasculardiseases—as well as related issues impacting the health oftrained athletes. Edited by Dr. Barry J. Maron, a world authority on HCM, and withmajor contributions from all of the international experts in thisfield, this book provides a single comprehensive source ofinformation concerning HCM. Recent advances in the field arediscussed, including the importance of left ventricular outflowtract obstruction, the use of implantable defibrillators for theprevention of sudden death in young people, definition of thegenetic basis for HCM and its role in clinical diagnosis and riskstratification, the development of more precise strategies forassessing the level of risk for sudden death among all patientswith HCM, and the evolution of invasive interventions for heartfailure symptoms, such as surgical management and its alternatives(alcohol septal ablation and dual-chamber pacing). Key Features: Contributions from all experts in the field,representing diverse viewpoints regarding this heterogeneousdisease and related issues in athletes Information to dispel misunderstandings regarding issuesassociated with HCM and cardiovascular disease in athletes The only comprehensive source of information available on thetopic
Publisher: John Wiley & Sons
ISBN: 140514615X
Category : Medical
Languages : en
Pages : 527
Book Description
Diagnosis and Management of Hypertrophic Cardiomyopathy is aunique, multi-authored compendium of information regarding thecomplexities of clinical and genetic diagnosis, natural history,and management of hypertrophic cardiomyopathy (HCM)—the mostcommon and important of the genetic cardiovasculardiseases—as well as related issues impacting the health oftrained athletes. Edited by Dr. Barry J. Maron, a world authority on HCM, and withmajor contributions from all of the international experts in thisfield, this book provides a single comprehensive source ofinformation concerning HCM. Recent advances in the field arediscussed, including the importance of left ventricular outflowtract obstruction, the use of implantable defibrillators for theprevention of sudden death in young people, definition of thegenetic basis for HCM and its role in clinical diagnosis and riskstratification, the development of more precise strategies forassessing the level of risk for sudden death among all patientswith HCM, and the evolution of invasive interventions for heartfailure symptoms, such as surgical management and its alternatives(alcohol septal ablation and dual-chamber pacing). Key Features: Contributions from all experts in the field,representing diverse viewpoints regarding this heterogeneousdisease and related issues in athletes Information to dispel misunderstandings regarding issuesassociated with HCM and cardiovascular disease in athletes The only comprehensive source of information available on thetopic
Frontiers in Noninvasive Cardiac Mapping, An Issue of Cardiac Electrophysiology Clinics
Author: Ashok Shah
Publisher: Elsevier Health Sciences
ISBN: 0323356745
Category : Medical
Languages : en
Pages : 185
Book Description
This issue of Cardiac Electrophysiology Clinics examines Frontiers in Non-invasive Cardiac Mapping. Topics include imaging of heart rhythm disorders, experimental validation and modeling of validation, challenges and future directions of inverse problems, phase mapping of cardiac fibrillation, frequency domain analysis, analysis of diagnostic 12-lead electrocardiography and 3D non-invasive mapping, and many more.
Publisher: Elsevier Health Sciences
ISBN: 0323356745
Category : Medical
Languages : en
Pages : 185
Book Description
This issue of Cardiac Electrophysiology Clinics examines Frontiers in Non-invasive Cardiac Mapping. Topics include imaging of heart rhythm disorders, experimental validation and modeling of validation, challenges and future directions of inverse problems, phase mapping of cardiac fibrillation, frequency domain analysis, analysis of diagnostic 12-lead electrocardiography and 3D non-invasive mapping, and many more.
Ventricular Arrhythmias
Author: John M. Miller
Publisher:
ISBN: 9781416062752
Category : Arrhythmia
Languages : en
Pages : 0
Book Description
Ventricular arrhythmias cause most cases of sudden cardiac death, which is the leading cause of death in the US. This issue reviews the causes of arrhythmias and the promising new drugs and devices to treat arrhythmias.
Publisher:
ISBN: 9781416062752
Category : Arrhythmia
Languages : en
Pages : 0
Book Description
Ventricular arrhythmias cause most cases of sudden cardiac death, which is the leading cause of death in the US. This issue reviews the causes of arrhythmias and the promising new drugs and devices to treat arrhythmias.
How Tobacco Smoke Causes Disease
Author: United States. Public Health Service. Office of the Surgeon General
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 728
Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 728
Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Research Awards Index
Clinical and Electrophysiologic Management of Syncope, An Issue of Cardiac Electrophysiology Clinics
Author: Antonio Raviele
Publisher: Elsevier Health Sciences
ISBN: 0323260896
Category : Medical
Languages : en
Pages : 177
Book Description
This issue of Cardiac Electrophysiology Clinics devoted to syncope a disorder that is associated with increased mortality. Internationally recognized experts discuss the many causes of syncope, helping the clinician to distinguish life-threatening etiologies from benign ones.
Publisher: Elsevier Health Sciences
ISBN: 0323260896
Category : Medical
Languages : en
Pages : 177
Book Description
This issue of Cardiac Electrophysiology Clinics devoted to syncope a disorder that is associated with increased mortality. Internationally recognized experts discuss the many causes of syncope, helping the clinician to distinguish life-threatening etiologies from benign ones.
Research Grants
Author: National Institutes of Health (U.S.). Division of Research Grants. Statistics and Analysis Branch
Publisher:
ISBN:
Category : Grants-in-aid
Languages : en
Pages : 500
Book Description
Publisher:
ISBN:
Category : Grants-in-aid
Languages : en
Pages : 500
Book Description
Subject Index of Current Research Grants and Contracts Administered by the National Heart, Lung and Blood Institute
Author: National Heart, Lung, and Blood Institute
Publisher:
ISBN:
Category : Cardiovascular system
Languages : en
Pages : 486
Book Description
Publisher:
ISBN:
Category : Cardiovascular system
Languages : en
Pages : 486
Book Description