Author: Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Results and Problems in Cell Differentiation
Author: Results and Problems in Cell Differentiation
Author: W. BeermannPublisher:
ISBN:
Category : Cell differentiation
Languages : en
Pages : 174
Book Description
Cell Cycle and Cell Differentiation
Author: J. ReinertPublisher: Springer Science & Business Media
ISBN: 354037390X
Category : Science
Languages : en
Pages : 336
Book Description
It is instructive to compare the response of biologists to the two themes that comprise the title of this volume. The concept of the cell cycle-in contra distinction to cell division-is a relatively recent one. Nevertheless biologists of all persuasions appreciate and readily agree on the central problems in this area. Issues ranging from mechanisms that initiate and integrate the synthesis of chro mosomal proteins and DNA during S-phase of mitosis to the manner in which assembly of microtubules and their interactions lead to the segregation of metaphase chromosomes are readily followed by botanists and zoologists, as well as by cell and molecular biologists. These problems are crisp and well-defined. The current state of "cell differentiation" stands in sharp contrast. This, one of the oldest problems in experimental biology, almost defies definition today. The difficulties arise not only from a lack of pertinent information on the regulatory mechanisms, but also from conflicting basic concepts in this field. One of the ways in which this situation might be improved would be to find a broader experimental basis, including a better understanding of the relationship between the cell cycle and cell differentiation.
Differentiation and Neoplasia
Author: R. G. McKinnellPublisher: Springer Science & Business Media
ISBN: 3540382674
Category : Medical
Languages : en
Pages : 327
Book Description
There is no commonly accepted mechanism to explain differentiation of either normal or neoplastic cells. Despite this fact, the organizers of the 3 rd International Conference on Differentiation recognized that there is much emerging evidence which supports the view that both normal cells and many cancer cells share common differentiative processes. Accordingly, the organizers perceived that clinical scientists and developmental biologists would greatly benefit by together considering differentiation. In that way, developmental biologists would be apprised of recent insights in cancer cell biology and the physician scientist would be updated on events in developmental biology and both would gain new understanding of the cell biology of neoplasia. A specific example may reveal the potential value of developmental biologists interacting with cancer physicians. An example chosen at random suggests that probably any paper included in the symposium volume would serve the purpose. Dr. Stephen Subtelny reviewed recent studies by his laboratory concerning germ cell migration and replication in frog embryos. How might those results interest the cancer scientist? Dr. Subtelny showed that primordial germ cells of a fertile graft will reverse their migratory direction and move into a sterile host. Perhaps in this context it would not be inappropriate to state that the germ cells of the graft metastasized into the host. Germ cells from grafts of a different species will populate the previously sterile host gonad.
Molecular Mechanisms of Cell Differentiation in Gonad Development
Author: Rafal P. PiprekPublisher: Springer
ISBN: 3319319736
Category : Science
Languages : en
Pages : 444
Book Description
This book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. It also discusses the processes leading to the testis- and ovary-specific structures and functions. The individual chapters review the origin and differentiation of the somatic cells of the genital ridges; the formation and migration of primordial germ cells in mouse and man; the gonadal supporting cell lineage and mammalian sex determination; differentiation of Sertoli and granulosa cells; mesonephric cell migration into the gonads and vascularization; origin and differentiation of androgen-producing cells in the gonads; germ cell commitment to the oogenic versus spermatogenic pathway and the role of retinoic acid; ovarian folliculogenesis; control of oocyte growth and development by intercellular communication within the follicular niche; biology of the Sertoli cell in the fetal, pubertal and adult mammalian testis; mechanisms regulating spermatogonial differentiation; stem cells in mammalian gonads; the role of microRNAs in cell differentiation during gonad development; human sex development and its disorders; as well as methods for the study of gonadal development.
Genetic Mosaics and Cell Differentiation
Author: W. J. GehringPublisher: Springer Science & Business Media
ISBN: 354035803X
Category : Science
Languages : en
Pages : 323
Book Description
The relationship of cell lineage and differentiation is one of the most intriguing problems in developmental biology. In most higher organisms, the analysis of the cell lineage has to rely on indirect methods. Only in the most suitable systems, like the nematodes, can the pattern of cell division be determined by direct observation under the microscope. In cases where this is not possible, the fate of the cells has to be examined by using cell markers. Most suitable for this purpose are genetic markers, provided that they do not interfere with the developmental pathway to be studied. However, suitable genetic markers and techniques for generating genetic mosaics are available in a few organisms only. Therefore, this volume is largely concerned with Drosophila and the mouse, which have been studied most extensively. In 1929 STURTEVANT introduced the analysis of gynandromorphs into devel opmental genetics. However, this important contribution remained largely unnoticed until the late sixties, when the potential of this technique for deter mining embryonic fate maps and the number of primordial cells was exploited, and the methodology extended to the mapping of mutational foci. Mitotic recombination was demostrated by STER:-
The Stability of the Differentiated State
Author: Joan AbbottPublisher: Springer
ISBN: 3662350890
Category : Science
Languages : en
Pages : 163
Book Description
Cell Differentiation
Author: J. M. AshworthPublisher: Springer Science & Business Media
ISBN: 9400957130
Category : Science
Languages : en
Pages : 64
Book Description
The development of an embryo is one of the which prevents entry of other sperm, fusion of most awe inspiring biological phenomena and the two haploid nuclei occurs and within about the study of cell differentiation can be traced 30 minutes the pigmented cortex rotates with respect to the underlying cytoplasm and in so back in antiquity to Aristotle and beyond However, there are few modern sciences which doing it reveals a grey, crescent shaped area on pay more than a cursory obeisance to their the side of the egg opposite to the point of founders and few students seem very interested entry of the sperm. This is another example of in the theories of their dead predecessors. polarity developing. Soon after fertilization the Embryology, though, is that rare exception - a zygote enters a period of rapid nuclear and cell division. The result of this cleavage process is science where the problems, theories and often that the egg cytoplasm is partitioned between techniques that excite our interest today, are essentially the same as those which excited our numerous cells whose ratio of nuclear volume to cytoplasmic volume is more like that found colleagues of fifty or even a hundred years ago. in an 'average' somatic cell.
Cell Cycle and Cell Differentiation
Author: Jakob ReinertNew Cell Differentiation Research Topics
Author: Hitoshi SaitamaPublisher: Nova Publishers
ISBN: 9781600219375
Category : Science
Languages : en
Pages : 324
Book Description
This new book presents research developments from around the globe in the field of cellular differentiation which is a concept from developmental biology describing the process by which cells acquire a 'type'. The morphology of a cell may change dramatically during differentiation, but the genetic material remains the same, with few exceptions. A cell that is able to differentiate into many cell types is known as pluripotent. These cells are called stem cells in animals and meristematic cells in higher plants. A cell that is able to differentiate into all cell types is known as totipotent. In mammals, only the zygote and early embryonic cells are totipotent, while in plants, many differentiated cells can become totipotent with simple laboratory techniques.