Author: W. G. Eisert Publisher: Springer Science & Business Media ISBN: 3642693342 Category : Medical Languages : en Pages : 343
Book Description
In October 1982, a small international symposium was held at the Gesellschaft fUr Strahlen- und Umweltforschung mbH (GSF) in Munich as a satellite meeting of the IX International Conference on Analytical Cytology. The symposium focussed on cytometric approaches to biological dosimetry, and was, to the best of our knowledge, the first meeting on this subject ever held. There was strong encouragement from the 75 attendees and from others to publish a proceedings of the symposium. Hence this book, containing 30 of the 36 presentations, has been assembled. Dosimetry, the accurate and systematic determination of doses, usually refers to grams of substance administered or rads of ionization or some such measure of exposure of a patient, a victim or an experimental system. The term also can be used to describe the quantity of an ultimate, active agent as delivered to the appropriate target material within a biological system. Thus, for mutagens, one can speak of DNA dosimetry, meaning the number of adducts produced in the DNA of target cells such as bone-mar row stem cells or spermatogonia.
Author: Pedro Andreo Publisher: John Wiley & Sons ISBN: 3527811044 Category : Science Languages : en Pages : 226
Book Description
Fosters a thorough understand of radiation dosimetry concepts: detailed solutions to the exercises in the textbook Fundamentals of Ionizing Radiation Dosimetry!
Author: National Research Council Publisher: National Academies ISBN: 0309039959 Category : Science Languages : en Pages : 436
Book Description
This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations.
Author: National Research Council Publisher: National Academies Press ISBN: 0309037891 Category : Science Languages : en Pages : 623
Book Description
This book describes hazards from radon progeny and other alpha-emitters that humans may inhale or ingest from their environment. In their analysis, the authors summarize in one document clinical and epidemiological evidence, the results of animal studies, research on alpha-particle damage at the cellular level, metabolic pathways for internal alpha-emitters, dosimetry and microdosimetry of radionuclides deposited in specific tissues, and the chemical toxicity of some low-specific-activity alpha-emitters. Techniques for estimating the risks to humans posed by radon and other internally deposited alpha-emitters are offered, along with a discussion of formulas, models, methods, and the level of uncertainty inherent in the risk estimates.
Author: Frank Herbert Attix Publisher: John Wiley & Sons ISBN: 3527617140 Category : Medical Languages : en Pages : 628
Book Description
A straightforward presentation of the broad concepts underlying radiological physics and radiation dosimetry for the graduate-level student. Covers photon and neutron attenuation, radiation and charged particle equilibrium, interactions of photons and charged particles with matter, radiotherapy dosimetry, as well as photographic, calorimetric, chemical, and thermoluminescence dosimetry. Includes many new derivations, such as Kramers X-ray spectrum, as well as topics that have not been thoroughly analyzed in other texts, such as broad-beam attenuation and geometrics, and the reciprocity theorem. Subjects are layed out in a logical sequence, making the topics easier for students to follow. Supplemented with numerous diagrams and tables.
Author: Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation Publisher: National Academies Press ISBN: 0309133343 Category : Science Languages : en Pages : 422
Book Description
This book is the seventh in a series of titles from the National Research Council that addresses the effects of exposure to low dose LET (Linear Energy Transfer) ionizing radiation and human health. Updating information previously presented in the 1990 publication, Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, this book draws upon new data in both epidemiologic and experimental research. Ionizing radiation arises from both natural and man-made sources and at very high doses can produce damaging effects in human tissue that can be evident within days after exposure. However, it is the low-dose exposures that are the focus of this book. So-called “late” effects, such as cancer, are produced many years after the initial exposure. This book is among the first of its kind to include detailed risk estimates for cancer incidence in addition to cancer mortality. BEIR VII offers a full review of the available biological, biophysical, and epidemiological literature since the last BEIR report on the subject and develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309175674 Category : Medical Languages : en Pages : 321
Book Description
Does radiation medicine need more regulation or simply better-coordinated regulation? This book addresses this and other questions of critical importance to public health and safety. The issues involved are high on the nation's agenda: the impact of radiation on public safety, the balance between federal and state authority, and the cost-benefit ratio of regulation. Although incidents of misadministration are rare, a case in Pennsylvania resulting in the death of a patient and the inadvertent exposure of others to a high dose of radiation drew attention to issues concerning the regulation of ionizing radiation in medicine and the need to examine current regulatory practices. Written at the request from the Nuclear Regulatory Commission (NRC), Radiation in Medicine reviews the regulation of ionizing radiation in medicine, focusing on the NRC's Medical Use Program, which governs the use of reactor-generated byproduct materials. The committee recommends immediate action on enforcement and provides longer term proposals for reform of the regulatory system. The volume covers: Sources of radiation and their use in medicine. Levels of risk to patients, workers, and the public. Current roles of the Nuclear Regulatory Commission, other federal agencies, and states. Criticisms from the regulated community. The committee explores alternative regulatory structures for radiation medicine and explains the rationale for the option it recommends in this volume. Based on extensive research, input from the regulated community, and the collaborative efforts of experts from a range of disciplines, Radiation in Medicine will be an important resource for federal and state policymakers and regulators, health professionals involved in radiation treatment, developers and producers of radiation equipment, insurance providers, and concerned laypersons.
Author: Rodolphe Antoni Publisher: Springer ISBN: 3319486608 Category : Science Languages : en Pages : 484
Book Description
This book describes the interaction of living matter with photons, neutrons, charged particles, electrons and ions. The authors are specialists in the field of radiation protection. The book synthesizes many years of experiments with external radiation exposure in the fields of dosimetry and radiation shielding in medical, industrial and research fields. It presents the basic physical concepts including dosimetry and offers a number of tools to be used by students, engineers and technicians to assess the radiological risk and the means to avoid them by calculating the appropriate shields. The theory of radiation interaction in matter is presented together with empirical formulas and abacus. Numerous numerical applications are treated to illustrate the different topics. The state of the art in radiation protection and dosimetry is presented in detail, especially in the field of simulation codes for external exposure to radiation, medical projects and advanced research. Moreover, important data spread in different up to date references are presented in this book. The book deals also with accelerators, X-rays facilities, sealed sources, dosimetry, Monte Carlo simulation and radiation regulation. Each chapter is split in two parts depending on the level of details the readers want to focus on. The first part, accessible to a large public, provides a lot of simple examples to help understanding the physics concepts under radiation external exposure. The second part, called “Additional Information” is not mandatory; it aims on explaining topics more deeply, often using mathematical formulations. The book treats fundamental radiometric and dosimetric quantities to describe the interaction in materials under the aspects of absorbed dose processes in tissues. Definitions and applications on limited and operational radiation protection quantities are given. An important aspect are practical engineering tools in industrial, medical and research domains. Source characterization and shielding design are addressed. Also more ”exotic” topics, such as ultra intense laser and new generation accelerators, are treated. The state of the art is presented to help the reader to work with the book in a self-consistent way. The basic knowledge necessary to apply Monte Carlo methods in the field of radiation protection and dosimetry for external radiation exposure is provided. Coverage of topics such as variance reduction, pseudo-random number generation and statistic estimators make the book useful even to experienced Monte Carlo practitioners. Solved problems help the reader to understand the Monte Carlo process. The book is meant to be used by researchers, engineers and medical physicist. It is also valuable to technicians and students.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309176115 Category : Medical Languages : en Pages : 107
Book Description
Over the past several decades, public concern over exposure to ionizing radiation has increased. This concern has manifested itself in different ways depending on the perception of risk to different individuals and different groups and the circumstances of their exposure. One such group are those U.S. servicemen (the "Atomic Veterans" who participated in the atmospheric testing of nuclear weapons at the Nevada Test Site or in the Pacific Proving Grounds, who served with occupation forces in or near Hiroshima and Nagasaki, or who were prisoners of war in or near those cities at the time of, or shortly after, the atomic bombings. This book addresses the feasibility of conducting an epidemiologic study to determine if there is an increased risk of adverse reproductive outcomes in the spouses, children, and grandchildren of the Atomic Veterans.
Author: Tamar Reeve Publisher: ISBN: 9781536135398 Category : Ionizing radiation Languages : en Pages : 0
Book Description
In this compilation, the authors examine the importance of ionizing radiations for thermoluminescence dosimetry that is the current area of research for medical and industrial purposes. Ionizing radiations are harmful to the human body, so, there is a need to measure small doses in the environment as well as very high doses at the time of accident like radiation leakage and for the treatment of cancer. Next, recent advances regarding effects on exposure of some foods to ionizing radiations are presented. The dosage required for complete sterilization may, at times, lead to undesirable changes in food flavours or may exceed the permitted levels. Combining irradiation with other treatments yields satisfactory results in these cases. Combined applications of ionizing radiation with heat, low temperature, high hydrostatic pressure, and modified atmospheres are also discussed. Later, new results concerning cell survival and genetic instability of wild-type and radiosensitive yeast cells of Saccharomyces cerevisiae surviving after irradiation with 60Co γ-rays, 239Pu α-particles and 254 nm UV light are presented. Survival was determined by cell ability to produce macrocolonies on a solid nutrient medium. The authors also review data on the radiation resistance of AlGaN/GaN and InAlN/GaN High Electron Mobility Transistors (HEMTs) as well as emerging Ga2O3 photodetectors and rectifiers to different types of ionizing radiation. Both of these wide bandgap semiconductor (nitride-based and gallium oxide-based) materials are much more radiation-hard than GaAs or Si and this is largely a result of their high bond strengths. By using the test system of blood lymphocytes of healthy individuals, the following paper presents the co-mutagenic (potentiating) effect of the drugs a calcium channel blocker verapamil and an antioxidant ascorbic acid-on the radiosensitivity of cells. It was found that when the lymphocytes are irradiated in a small dose (0.3 Gy), ascorbic acid (80.0 μg / blood) and verapamil (4.0 μg / ml blood) increase the frequency of chromosomal aberrations in comparison with the radiation effect by 75 and 62, 5% respectively. Afterwards, the experimental data of the effects of temperature, light intensity, background ionizing and non-ionizing radiation on physicochemical properties of water, water solution and cell function are presented. Considering the fact that the cell membrane permeability for water is more than 10 times higher than for inorganic ions, it is hypothesized that, upon the effect of chemical and physical factors, the changes of net water efflux through the membrane precede the activation of ionic fluxes in the membrane. Also in this compilation, a study is included which investigated the modifying effect of astaxanthin on radiation induced genome damages in cultivating human peripheral blood lymphocytes (PBL). The study indicated that astaxanthin in concentration of 20.0 �g/ml demonstrated evident radioprotective properties by reduction of the ChA level, decreasing of DNA damages and increasing of the apoptotic rate. In the last chapter, the authors present some works that study the causes of the high resistance of IRRB to ionizing radiation. Then we focus on presenting in silico approaches that use protein sequences of bacteria in order to predict if an unknown bacterium belongs to IRRB or ionizing-radiationsensitive bacteria (IRSB).
Author: W. G. Eisert
Author: Pedro Andreo
Author: National Research Council
Author: National Research Council
Author: Frank Herbert Attix
Author: Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation
Author: Institute of Medicine
Author: Rodolphe Antoni
Author: Institute of Medicine
Author: Tamar Reeve