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Author: United States. Public Health Service. Office of the Surgeon General Publisher: ISBN: Category : Government publications Languages : en Pages : 728
Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Author: United States. Public Health Service. Office of the Surgeon General Publisher: ISBN: Category : Government publications Languages : en Pages : 728
Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Author: OECD Publisher: OECD Publishing ISBN: 9264279083 Category : Languages : en Pages : 258
Book Description
This report examines how the two global mega-trends of population ageing and rising inequalities have been developing and interacting, both within and across generations.
Author: José Manuel Salazar-Xirinachs Publisher: ISBN: 9789221285663 Category : Developed countries Languages : en Pages : 400
Book Description
This book helps connect the dots between economic theory, the role of capabilities, the lessons from history and the practical challenges of design and implementation of industrial policies. In so doing it provides an excellent policy roadmap for anyone interested in the challenge of promoting catch-up growth and productive transformation.
Author: Collectif Publisher: OECD ISBN: 9264301763 Category : Business & Economics Languages : en Pages : 260
Book Description
This interim report of the OECD/G20 Inclusive Framework on BEPS is a follow-up to the work delivered in 2015 under Action 1 of the BEPS Project on addressing the tax challenges of the digital economy. It sets out the Inclusive Framework’s agreed direction of work on digitalisation and the international tax rules through to 2020. It describes how digitalisation is also affecting other areas of the tax system, providing tax authorities with new tools that are translating into improvements in taxpayer services, improving the efficiency of tax collection and detecting tax evasion.
Author: Patrick Waller Publisher: John Wiley & Sons ISBN: 1119289785 Category : Medical Languages : en Pages : 192
Book Description
Pharmacovigilance is the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug-related problems. This introductory guide is designed to aid the rapid understanding of the key principles of pharmacovigilance. Packed full of examples illustrating drug safety issues it not only covers the processes involved, but the regulatory aspects and ethical and societal considerations of pharmacovigilance. Covering the basics step-by-step, this book is perfect for beginners and is essential reading for those new to drug safety departments and pharmaceutical medicine students. The second edition is thoroughly revised and updated throughout and includes a new chapter on clinical aspects of pharmacovigilance.
Author: Mira Harrison-Woolrych Publisher: Springer ISBN: 3319124064 Category : Medical Languages : en Pages : 624
Book Description
In this definitive new text, the major medicines, devices and vaccines used by women worldwide are brought together for the first time in a single volume. Written and edited by international experts with an evidence-based approach, the book offers a comprehensive summary of all the key areas of women’s medicines. In the first part, issues relating to female drug exposure and considerations for prescribing for subgroups of women - for example during pregnancy and lactation - are presented in the context of contemporary clinical practice. In the second part, specific groups of pharmaceutical products are reviewed, including oral contraceptives, emergency contraception, treatment of chronic pelvic pain, hormone replacement therapy, bisphosphonates, herbal medicines for women, contraceptive devices and human papilloma virus (HPV) vaccines. Every chapter reviews and summarises the efficacy and safety of each group of products and concludes with a useful set of clinical take home messages. In the third part, broader perspectives are presented - from a primary care overview of prescribing for women, through to regulatory, political and religious aspects, including issues with women’s medicines in developing countries. The final two chapters focus on risk communication and conclude that women themselves should be placed at the centre of all discussions about their medicines. The book is aimed at prescribers, other healthcare professionals and students in the field of women’s health throughout the world. It is an extremely valuable resource for all in clinical practice, for students of medicine, nursing, pharmacy and related sciences, and also for those in medicines regulation, pharmacovigilance and the pharmaceutical industry.
Author: William B. Swann Publisher: Amer Psychological Assn ISBN: 9781557985316 Category : Social Science Languages : en Pages : 324
Book Description
Once the province of a small group of theorists and researchers operating on the periphery of psychological science, gender research has charged into the psychological mainstream during the last two decades. In large measure, Janet T. Spence has been responsible for this transformation, challenging the traditional ideas of fundamental difference between men and women. The simple idea of difference, once used to rationalize prejudices and discrimination, has now been replaced by a complex, sophisticated awareness of how gender is constructed and maintained. This book explores new empirical work and theoretical models about the causes and consequences of constructing gender.
Author: Alejandro Portes Publisher: ISBN: Category : Business & Economics Languages : en Pages : 344
Book Description
A New York roofer requests payment in cash. A Bogota car mechanic sets up "shop" on a quiet side street. Four Mexican immigrants assemble semiconductors in a San Diego home. A Leningrad doctor sells needed medicine to a desperate patient. All are part of a growing worldwide phenomenon that is widely known but little understood. The informal or underground economy is thriving today, not only in the Third World countries where it was first reported and studied but also in Eastern Europe and the developed nations of the West. The Informal Economy is the first book to bring together studies from all three of these settings and to integrate them into a coherent theoretical framework. Taking an international perspective, the authors dispel a number of misconceptions about the informal economy. They make clear, for instance, that it is not solely a province of the poor. Cutting across social strata, it reflects a political and economic realignment between employers and workers and a shift in the regulatory mission of the government. Throughout, the authors' theoretical observations serve not only to unify material from diverse sources but also to map out directions for further research.
Author: Arvid Aage Skaar Publisher: Kluwer Law International B.V. ISBN: 9403520647 Category : Law Languages : en Pages : 957
Book Description
A new edition of the preeminent work on the permanent establishment (PE) is a major event in tax law scholarship. Taking into account changes in judicial and administrative practice as well as the Organisation for Economic Co-operation and Development’s (OECD’s) and the United Nation’s (UN’s) work in the three decades since the first edition, the present study brings the analysis up to date with the current internationally accepted interpretation of PE. The analysis is based on more than 720 cases from more than 20 countries, in addition to the OECD and UN model treaties and more than 630 books, articles, and official documents. The increased significance of the digital economy has rendered the traditional concept of PE inadequate for the allocation of taxing jurisdiction over the modern, mobile or digital international business. The author’s in-depth analysis explains the legal elements of the PE principle with attention to their continuing benefit and their shortcomings: criteria defining a PE- place of business, location, right of use, duration, business connection, business activity, ordinary course of business; evidence of a right of use to a place of business; business activities included in the PE concept of the tax treaties; identification of projects offshore and onshore; UN model treaty deviations from the OECD agency clause; distinction between jurisdictions with significant natural resources and countries possessing the capital, technology and know-how necessary to explore and exploit these resources; and how policies in each country may erode the PE concept. The book provides many synopses of court decisions and administrative rulings upon which the analysis is based. In addition to cases previously published in law reports and other publications, a number of unpublished decisions are included. A key word index makes it easy to find what is needed in any particular matter. The PE principle, in one version or another, is used in several thousand tax treaties in force today. This updated comprehensive study reveals the obligations imposed through the use of PE in tax treaties and will continue to be of immeasurable value to tax practitioners and scholars worldwide. In addition, the discussion of whether the notion of PE is an appropriate criterion for taxing jurisdiction in international fiscal law today provides authoritative and insightful food for thought.
Author: United States. Public Health Service. Office of the Surgeon General
Author: United States. Public Health Service. Office of the Surgeon General
Author: OECD
Author: José Manuel Salazar-Xirinachs
Author: Collectif
Author: Marion Jansen
Author: Patrick Waller
Author: Mira Harrison-Woolrych
Author: William B. Swann
Author: Alejandro Portes
Author: Arvid Aage Skaar