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Author: Giuseppe Filardo Publisher: Springer Nature ISBN: 3030847446 Category : Medical Languages : en Pages : 394
Book Description
This book presents the evidence related to the use of injectable biologics to provide faster and better healing for musculoskeletal lesions and conditions. The authors discuss approaches, such as blood derivatives and cell concentrates, applied to lesions of muscles, ligaments, tendons, bones, meniscus and cartilage, as well as osteoarthritis. Chapters are written by some of the most influential opinion leaders in the field, with up-to-date review of the current literature, where the authors explore both the potential and the limitations of these minimally invasive and promising treatments. The first section is devoted to the formulations and rationale for the use of injectable orthobiologics, while the second section reviews current treatment methods applied to specific joints and pathologies – ranging from tendinopathies through non-unions to articular degenerative processes – as well as the results of these treatment approaches. The third section explores future perspectives, such as pluripotent stem cells, gene therapy, and the stimulation of intrinsic stromal cell niches. Appealing to a broad readership, this book will be of interest to both laboratory research scientists and clinicians, including orthopedists, sports physicians, physiatrists, and regenerative medicine experts.
Author: Giuseppe Filardo Publisher: Springer Nature ISBN: 3030847446 Category : Medical Languages : en Pages : 394
Book Description
This book presents the evidence related to the use of injectable biologics to provide faster and better healing for musculoskeletal lesions and conditions. The authors discuss approaches, such as blood derivatives and cell concentrates, applied to lesions of muscles, ligaments, tendons, bones, meniscus and cartilage, as well as osteoarthritis. Chapters are written by some of the most influential opinion leaders in the field, with up-to-date review of the current literature, where the authors explore both the potential and the limitations of these minimally invasive and promising treatments. The first section is devoted to the formulations and rationale for the use of injectable orthobiologics, while the second section reviews current treatment methods applied to specific joints and pathologies – ranging from tendinopathies through non-unions to articular degenerative processes – as well as the results of these treatment approaches. The third section explores future perspectives, such as pluripotent stem cells, gene therapy, and the stimulation of intrinsic stromal cell niches. Appealing to a broad readership, this book will be of interest to both laboratory research scientists and clinicians, including orthopedists, sports physicians, physiatrists, and regenerative medicine experts.
Author: Robert Alan Bonakdar Publisher: Oxford University Press ISBN: 0199315248 Category : Medical Languages : en Pages : 929
Book Description
Integrative Pain Management is a comprehensive guide written by experts in the field that provides case examples of pain conditions, reviews common integrative treatments including physical therapy, behavioral strategies, and advanced procedures to maximize function and reduce pain; and with extensive resources.
Author: Masaki Ieda Publisher: Springer ISBN: 3319561065 Category : Medical Languages : en Pages : 277
Book Description
This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged. The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.
Author: Grant Cooper Publisher: Springer Nature ISBN: 3030427714 Category : Medical Languages : en Pages : 268
Book Description
Regenerative medicine (RM) is a rapidly expanding topic within orthopedic and spine surgery, sports medicine and rehabilitation medicine. In the last ten years, regenerative medicine has emerged from the fringes as a complement and challenge to evidence-based medicine. Both clinicians and patients alike are eager to be able to offer and receive treatments that don't just surgically replace or clean old joints or inject away inflammation or work as a stop-gap measure. Regenerative medicine encompasses everything from the use of stem cells and platelet-rich plasma (PRP) to prolotherapy, viscosupplementation and beyond. This book will provide healthcare practitioners dealing with spine and joint pain with the most current, up-to-date evidence-based information about which treatments work, which treatments don't, and which are on the horizon as potential game changers. Chapters are arranged in a consistent format and cover the spine, shoulder, elbow, hand and wrist, hip, knee, and foot and ankle, providing a thorough, top-to-bottom approach. A concluding chapter discusses current and future directions and applications of RM over the next decade or two. Timely and forward-thinking, Regenerative Medicine for Spine and Joint Pain will be a concise and practical resource for orthopedists, spine surgeons, sports medicine specialists, physical therapists and rehabilitation specialists, and primary care providers looking to expand their practice.
Author: Gerard A. Malanga, MD Publisher: Springer Publishing Company ISBN: 1617052892 Category : Medical Languages : en Pages : 305
Book Description
Regenerative medicine offers physicians new tools to help repair damaged tissue, alleviate pain, accelerate healing, and improve function for patients with degenerative conditions or sports injuries. Regenerative Treatments in Sports and Orthopedic Medicine is the first comprehensive book devoted to orthobiologic treatments for orthopedic conditions. Authored by experts in regenerative medicine, this evidence- and experience-based guide is written for clinicians looking to understand and effectively implement these treatments in their practices. Broad yet focused coverage of the scientific underpinnings, regulatory issues, staffing and equipment, nutritional and rehabilitation concerns, and orthobiologic interventions for specific clinical problems make this the ideal procedural reference for anyone working to restore function to athletes or other patients with musculoskeletal pathologies. Key Features Unparallelled coverage of clinical science and practical applications Written by pioneering leaders at the forefront of an emerging standard of care Evidence-based indications for initiating orthobiologic therapies Includes a review of important nomenclature for the novice Covers both Platelet Rich Plasma (PRP) and stem cell procedures A must-read guide for practitioners in academic and private practice settings
Author: Ross Carter Publisher: ISBN: 9781543182620 Category : Languages : en Pages : 166
Book Description
The Cellular Regeneration Method is a groundbreaking combination of regenerative treatments to ELIMINATE knee, hip, shoulder, and spine pain NATURALLY in 30 days or less, without dangerous surgery or addictive medications. The Cellular Regeneration Method produces truly amazing results with patients who have been suffering for years with chronic pain in their joints and/or spine and living with limitations and who have not achieved lasting results by any other means. In this book, you will discover the 3 phases of healing using treatment from ethically derived stem cells. You will also find testimonials from real people and their real-life transformations from suffering to a life with restored happiness, joy, energy, and pain-free mobility.
Author: Lucas G. Chase Publisher: Springer Science & Business Media ISBN: 1627032002 Category : Science Languages : en Pages : 458
Book Description
Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.
Author: Neil H. Riordan Publisher: Neil H Riordan ISBN: 9780999045305 Category : Health & Fitness Languages : en Pages : 302
Book Description
Stem cells are the repair cells of your body. When there aren't enough of them, or they aren't working properly, chronic diseases can manifest and persist. From industry leaders, sport stars, and Hollywood icons to thousands of everyday, ordinary people, stem cell therapy has helped when standard medicine failed. Many of them had lost hope. These are their stories. Neil H Riordan, author of MSC: Clinical Evidence Leading Medicine's Next Frontier, the definitive textbook on clinical stem cell therapy, brings you an easy-to-read book about how and why stem cells work, and why they're the wave of the future.
Author: Stephan Becker Publisher: Springer Science & Business Media ISBN: 3211742212 Category : Medical Languages : en Pages : 169
Book Description
This is the first book to cover minimal-invasive treatment of osteoporotic, tumorous and traumatic vertebral fractures in the English language. In addition to detailed descriptions of the techniques, including tips and tricks from experts, the book contains a chapter about the medical treatment of osteoporosis, which is indispensable in the interdisciplinary approach to osteoporosis. This acclaimed innovative concept unites several treatment aspects. More conservative treatment methods are also presented in this work. All chapters reflect new developments and clinical findings in the field of orthopaedics, surgery, traumatology and neurosurgery.
Author: Giuseppe Filardo
Author: Giuseppe Filardo
Author: ASIPP Publishing
Author: Robert Alan Bonakdar
Author: Masaki Ieda
Author: Grant Cooper
Author: Gerard A. Malanga, MD
Author: Ross Carter
Author: Lucas G. Chase
Author: Neil H. Riordan
Author: Stephan Becker