Cardiac Receptors PDF Download

Author: R. Hainsworth
Publisher: CUP Archive
ISBN: 9780521218535
Category : Medical
Languages : en
Pages : 544

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Author: Rosaria Meccariello
Publisher: BoD – Books on Demand
ISBN: 9535124293
Category : Medical
Languages : en
Pages : 260

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Book Description
This book provides a comprehensive overview of current knowledge of cannabinoid activity in human physiology and points out the importance of endocannabinoid system for the maintenance of human health and treatment of diseases. Each chapter has been organized with the aim to cover basic concepts in the modulation of endocannabinoid system in both physiological and pathological conditions, thanks to the integration of data from experimental animal models and clinical observations. A special focus has been put on the medical use of cannabinoids and on the targeting of endocannabinoid system as new therapeutic strategy for the prevention and treatment of human diseases. Taken together, this book targets a wide audience of basic and clinical scientists, teachers and students interested in gaining a better understanding in the field of cannabinoids.

Author: Rolf Uddman
Publisher: Academic Press
ISBN: 0323148077
Category : Medical
Languages : en
Pages : 498

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Book Description
Vascular Innervation and Receptor Mechanisms: New Perspectives reviews the areas of structure, function, and pathophysiology of the circulatory system. The text focuses on the role of neuropeptides and structural function of endothelium. The book begins with a brief discussion on the background of autonomic and sensory nerves in the circulatory system, which is provided in Chapter 1. Having established the basic studies in the circulatory system, the book moves to the discussion on the analysis of peptidergic innervations and peptides in vascular control in various disorders. The last part of the book features the clinical applications of neuropeptides, perivascular peptides, and vasoactive peptides in different diseases and regulation, such as cardiovascular regulation, hypertension, congestive heart failure, and migraine and cluster headache. The text will be a good reference to both students and professionals in the fields of biology, chemistry, and medicine.

Author: Michitoshi Inoue
Publisher: Springer Science & Business Media
ISBN: 4431683674
Category : Medical
Languages : en
Pages : 330

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Book Description
Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.

Author: David C. Gaze
Publisher: BoD – Books on Demand
ISBN: 1839681616
Category : Medical
Languages : en
Pages : 356

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Book Description
This is the latest book in a series of cardiovascular-related texts from IntechOpen Publishing. The present volume considers general aspects of cardiac disease and is divided into three distinct sections covering cardiac risk, cardiorenal pathology, and novel interventional surgical techniques. The chapters offer insight into the current state of the art with respect to the risks of developing cardiovascular diseases, maintenance of patent vascular access in patients with the cardiorenal syndrome, and a plethora of novel interventional technologies all aimed at salvaging damaged tissue and improving prognosis and reducing mortality. This volume of 18 chapters is intended for general medical and biomedical students at both undergraduate and postgraduate level. It also offers insightful updates on recent advances in the understanding of the pathophysiology of cardiac diseases and the new techniques added to the medical armamentarium to improve the outcomes and prevent mortality and would be of interest to those working in academia and healthcare science.

Author: Michel Félétou
Publisher: Morgan & Claypool Publishers
ISBN: 1615041230
Category : Science
Languages : en
Pages : 309

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Book Description
The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References

Author: Ashok K. Srivastava
Publisher: Springer Science & Business Media
ISBN: 0387095519
Category : Medical
Languages : en
Pages : 426

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Book Description
Signal Transduction in Cardiovascular System Health and Disease highlights the major contributions of different signaling systems in modulating normal cardiovascular functions and how a perturbation in these signaling events leads to abnormal cell functions and cardiovascular disorders. This title is volume 3 in the new Springer series, Advances in Biochemistry in Health and Disease.

Author: Anthony P. Davenport
Publisher: Springer Science & Business Media
ISBN: 1592599273
Category : Medical
Languages : en
Pages : 246

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Book Description
A comprehensive collection of readily reproducible methods for studying receptors in silico, in vitro, and in vivo. These cutting-edge techniques cover mining from curated databases, identifying novel receptors by high throughput screening, molecular methods to identify mRNA encoding receptors, radioligand binding assays and their analysis, quantitative autoradiography, and imaging receptors by positron emission tomography (PET). Highlights include phenotypic characterization of receptors in knockout mice, imaging receptors using green fluorescent protein and fluorescent resonance energy transfer, and quantitative analysis of receptor mRNA by TaqMan PCR. These book equips the researcher with techniques for exploring the unprecedented number of new receptor systems now emerging and the so-called "orphan" receptors whose activating ligand has not been identified.

Author: Viacheslav Nikolaev
Publisher: Springer
ISBN: 3319545795
Category : Medical
Languages : en
Pages : 383

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Book Description
The book comprehensively presents new findings in cardiovascular research related to signaling microdomains in health and disease. Important second messengers such as cAMP, cGMP, calcium and their role in microdomain signaling are discussed. The book offers and explains methodical approaches and technical ways how to successfully analyze microdomain signaling, also in the context of disease. It further provides scientific perspectives and strategies that are based on the concept of signaling within microdomains and that can revolutionize pharmacology and eventually lead to the effective treatment of cardiovascular diseases in future.This book is written for scientists in cardiovascular research, pharmacology, molecular and cellular biology as well as medical doctors in cardiology, angiology and nephrology.

Author: Thomas Brand
Publisher: MDPI
ISBN: 3038429899
Category : Medical
Languages : en
Pages : 307

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Book Description
This book is a printed edition of the Special Issue "Cyclic Nucleotide Signaling and the Cardiovascular System" that was published in JCDD