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Author: Tilak Saha Publisher: Bentham Science Publishers ISBN: 981512398X Category : Science Languages : en Pages : 270
Book Description
Recent Trends and the Future of Antimicrobial Agents provides a significantly expanded overview of the topic with updated research in a broader context on the development of alternative approaches against microbial infections. This part primarily describes the use of probiotics, chemically synthesized compounds and nanomaterials as antimicrobial agents. The first chapter describes the potential of probiotics for the restoration of gut microbiomes. Amongst various antimicrobial agents, the use of antibodies has recently been investigated as a potential remedy. A chapter on antibody-based therapy as an alternative to antibiotics has been included. Chemical synthesis has eased the development of target-based prospective drug molecules against microorganisms. Chemically synthesized cationic amphiphiles and amphiphilic nanocarriers as antimicrobial agents have been discussed with sufficient detail in two different chapters. Research and progress in Schiff Base-Metal Complexes and Metal-Organic Frameworks for their antimicrobial applications have also been described in two separate chapters. Independent chapters discussing the design, synthesis and antimicrobial applications of biogenic metal or metalloid nanoparticles, bactericidal QDs and MoS2-based antibacterial nanocomposites have fulfilled the aim of incorporating cutting-edge research in the areas of alternative antimicrobials. Also, a new-age approach to combat microbes, antimicrobial photodynamic therapy (aPDT), is discussed in the final chapter of the edited volume. This part intends to provide the readers with an updated and broad view of research and development in alternative remedial approaches against microbial infections. The contents cater to the information needs of professionals and learners in academia, industry and health services who aim to learn the most significant experimental and practical approaches towards finding alternatives to existing antimicrobial therapies.
Author: Tilak Saha Publisher: Bentham Science Publishers ISBN: 981512398X Category : Science Languages : en Pages : 270
Book Description
Recent Trends and the Future of Antimicrobial Agents provides a significantly expanded overview of the topic with updated research in a broader context on the development of alternative approaches against microbial infections. This part primarily describes the use of probiotics, chemically synthesized compounds and nanomaterials as antimicrobial agents. The first chapter describes the potential of probiotics for the restoration of gut microbiomes. Amongst various antimicrobial agents, the use of antibodies has recently been investigated as a potential remedy. A chapter on antibody-based therapy as an alternative to antibiotics has been included. Chemical synthesis has eased the development of target-based prospective drug molecules against microorganisms. Chemically synthesized cationic amphiphiles and amphiphilic nanocarriers as antimicrobial agents have been discussed with sufficient detail in two different chapters. Research and progress in Schiff Base-Metal Complexes and Metal-Organic Frameworks for their antimicrobial applications have also been described in two separate chapters. Independent chapters discussing the design, synthesis and antimicrobial applications of biogenic metal or metalloid nanoparticles, bactericidal QDs and MoS2-based antibacterial nanocomposites have fulfilled the aim of incorporating cutting-edge research in the areas of alternative antimicrobials. Also, a new-age approach to combat microbes, antimicrobial photodynamic therapy (aPDT), is discussed in the final chapter of the edited volume. This part intends to provide the readers with an updated and broad view of research and development in alternative remedial approaches against microbial infections. The contents cater to the information needs of professionals and learners in academia, industry and health services who aim to learn the most significant experimental and practical approaches towards finding alternatives to existing antimicrobial therapies.
Author: National Research Council Publisher: National Academies Press ISBN: 0309180686 Category : Medical Languages : en Pages : 102
Book Description
Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309185548 Category : Medical Languages : en Pages : 397
Book Description
Infectious diseases are a global hazard that puts every nation and every person at risk. The recent SARS outbreak is a prime example. Knowing neither geographic nor political borders, often arriving silently and lethally, microbial pathogens constitute a grave threat to the health of humans. Indeed, a majority of countries recently identified the spread of infectious disease as the greatest global problem they confront. Throughout history, humans have struggled to control both the causes and consequences of infectious diseases and we will continue to do so into the foreseeable future. Following up on a high-profile 1992 report from the Institute of Medicine, Microbial Threats to Health examines the current state of knowledge and policy pertaining to emerging and re-emerging infectious diseases from around the globe. It examines the spectrum of microbial threats, factors in disease emergence, and the ultimate capacity of the United States to meet the challenges posed by microbial threats to human health. From the impact of war or technology on disease emergence to the development of enhanced disease surveillance and vaccine strategies, Microbial Threats to Health contains valuable information for researchers, students, health care providers, policymakers, public health officials. and the interested public.
Author: Jun Lin Publisher: Frontiers Media SA ISBN: 2889195260 Category : Antibiotics Languages : en Pages : 226
Book Description
Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.
Author: Manuel Simoes Publisher: Academic Press ISBN: 0128194987 Category : Science Languages : en Pages : 418
Book Description
Recent Trends in Biofilm Science and Technology helps researchers working on fundamental aspects of biofilm formation and control conduct biofilm studies and interpret results. The book provides a remarkable amount of knowledge on the processes that regulate biofilm formation, the methods used, monitoring characterization and mathematical modeling, the problems/advantages caused by their presence in the food industry, environment and medical fields, and the current and emergent strategies for their control. Research on biofilms has progressed rapidly in the last decade due to the fact that biofilms have required the development of new analytical tools and new collaborations between biologists, engineers and mathematicians. - Presents an overview of the process of biofilm formation and its implications - Provides a clearer understanding of the role of biofilms in infections - Creates a foundation for further research on novel control strategies - Updates readers on the remarkable amount of knowledge on the processes that regulate biofilm formation
Author: Richard Schwalbe Publisher: CRC Press ISBN: 1420014498 Category : Medical Languages : fr Pages : 430
Book Description
The clinical microbiology laboratory is often a sentinel for the detection of drug resistant strains of microorganisms. Standardized protocols require continual scrutiny to detect emerging phenotypic resistance patterns. The timely notification of clinicians with susceptibility results can initiate the alteration of antimicrobial chemotherapy and
Author: W. Scott Champney Publisher: Springer Science & Business Media ISBN: 1588299155 Category : Medical Languages : en Pages : 274
Book Description
This book examines specific techniques which can be used to explore new drug targets and the effectiveness of new antibiotics. By testing new antimicrobial agents and modified existing drugs, the most vulnerable cell processes, such as cell wall and membrane synthesis, DNA replication, RNA transcription and protein synthesis, can be better exploited. This in-depth volume, however, delves even deeper by identifying additional novel cellular targets for these new therapies. The book will provide laboratory investigators with the vital tools they need to test the antimicrobial potential of products and to curb the rise of so many infectious diseases.
Author: King K. Holmes Publisher: World Bank Publications ISBN: 1464805253 Category : Medical Languages : en Pages : 1027
Book Description
Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
Author: Amit Basak Publisher: Springer ISBN: 8132227824 Category : Science Languages : en Pages : 254
Book Description
Fungal infections have taken a new spectrum due to the increased incidence of multi-drug resistant fungal pathogens. Freedom of choice for drugs to treat fungal infections is also narrow because of lesser probability of discovering drugs that would bypass affecting human cells and target fungal cells producing fewer side effects in patients. An approach has gained prominence in research is to look for bioactive antifungal compounds from natural to synthetic sources. It is necessary to discover new classes of antifungals to control the recent emergence of multi-drug resistant fungal infections. This book proposed a details top to bottom outline of antifungal compounds derived naturally or synthetically. The details of their modifications or synthetic analogues have been described, helpful to understand the structure-activity relationship which leads to new compound development in antifungal chemotherapy. Each chapter begins with a comprehensive, top-bottom in-depth discussion of antifungal agents with updated bibliographic references. This compendium will serve as a companion not only for Scientists, Researchers, and Professors, Medical Practitioners but also a valuable reference text for the university students.
Author: Jince Thomas Publisher: CRC Press ISBN: 1000793389 Category : Science Languages : en Pages : 431
Book Description
Recent trends in Nanomedicine and Tissue Engineering covers numerous recent technological and research accomplishments in the area of Nanomedicine and Tissue Engineering. The introduction of nanomaterials and nanotechnology have led to crucial advancements in the fields of nanomedicine and tissue engineering, as well as cancer therapies and drug delivery systems.The book follows recent trends in drug delivery systems, wound healing fields, cancer therapies, protection of teeth and also other health care systems.Technical topics discussed in the book include:• Nanorobots• Tissue engineering• Gene therapy• Drug delivery• Nanomotors• Nanogels.
Author: Tilak Saha
Author: Tilak Saha
Author: National Research Council
Author: Institute of Medicine
Author: Jun Lin
Author: Manuel Simoes
Author: Richard Schwalbe
Author: W. Scott Champney
Author: King K. Holmes
Author: Amit Basak
Author: Jince Thomas