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Author: Attila Gacser Publisher: Frontiers Media SA ISBN: 2889450627 Category : Languages : en Pages : 150
Book Description
Fungal infections represent nowadays a significant burden on the healthcare system of most of the countries, and are among the infections with the highest mortality rates. This has fostered the study of the interaction of these organisms with the human host. The outer most layer of a fungal cell is the cell wall, and together with the secreted components into the extracellular compartment, are the first lines of contact with the host cells. This interaction is critical for tissue adhesion, colonization and damage. In addition, these fungal extracellular components will define the outcome of the interaction with the host immune cells, leading either to the establishment of a protective antifungal immune response or to an immune-evasive mechanism by the fungal cell. On the other hand, our immune system has effectively evolved to deal with fungal pathogens, developing strategies for cell eradication, burden control, or antigen presentation from the innate branch to the adaptive immune response. Here, we provide a series of comprehensive review papers dealing with both aspect of the interaction fungus-immune cells: the role of virulence factors and cell wall components during such interaction, and the recent advances in the study of cellular receptors in the establishment of a protective anti-fungal immune response.
Author: Attila Gacser Publisher: Frontiers Media SA ISBN: 2889450627 Category : Languages : en Pages : 150
Book Description
Fungal infections represent nowadays a significant burden on the healthcare system of most of the countries, and are among the infections with the highest mortality rates. This has fostered the study of the interaction of these organisms with the human host. The outer most layer of a fungal cell is the cell wall, and together with the secreted components into the extracellular compartment, are the first lines of contact with the host cells. This interaction is critical for tissue adhesion, colonization and damage. In addition, these fungal extracellular components will define the outcome of the interaction with the host immune cells, leading either to the establishment of a protective antifungal immune response or to an immune-evasive mechanism by the fungal cell. On the other hand, our immune system has effectively evolved to deal with fungal pathogens, developing strategies for cell eradication, burden control, or antigen presentation from the innate branch to the adaptive immune response. Here, we provide a series of comprehensive review papers dealing with both aspect of the interaction fungus-immune cells: the role of virulence factors and cell wall components during such interaction, and the recent advances in the study of cellular receptors in the establishment of a protective anti-fungal immune response.
Author: Publisher: ISBN: Category : Languages : en Pages : 0
Book Description
Fungal infections represent nowadays a significant burden on the healthcare system of most of the countries, and are among the infections with the highest mortality rates. This has fostered the study of the interaction of these organisms with the human host. The outer most layer of a fungal cell is the cell wall, and together with the secreted components into the extracellular compartment, are the first lines of contact with the host cells. This interaction is critical for tissue adhesion, colonization and damage. In addition, these fungal extracellular components will define the outcome of the interaction with the host immune cells, leading either to the establishment of a protective antifungal immune response or to an immune-evasive mechanism by the fungal cell. On the other hand, our immune system has effectively evolved to deal with fungal pathogens, developing strategies for cell eradication, burden control, or antigen presentation from the innate branch to the adaptive immune response. Here, we provide a series of comprehensive review papers dealing with both aspect of the interaction fungus-immune cells: the role of virulence factors and cell wall components during such interaction, and the recent advances in the study of cellular receptors in the establishment of a protective anti-fungal immune response.
Author: Eleftherios Mylonakis Publisher: Springer Science & Business Media ISBN: 1441956387 Category : Science Languages : en Pages : 135
Book Description
Most studies of bacterial or fungal infectious diseases focus separately on the pathogenic microbe, the host response, or the characterization of therapeutic compounds. Compartmentalization of pathogenesis-related research into an analysis of the “pathogen”, the “host,” or the “antimicrobial compound” has largely been dictated by the lack of model systems in which all of these approaches can be used simultaneously, as well as by the traditional view that microbiology, immunology, and chemical biology and pharmacology are separate disciplines. An increasing number of workers from different fields have turned to insects, fish, worms and other model hosts as facile, ethically expedient, relatively simple, and inexpensive hosts to model a variety of human infectious diseases and to study host responses and innate immunity. Because many of these hosts are genetically tractable, they can be used in conjunction with an appropriate pathogen to facilitate the discovery of novel features of the host innate immune response. This book provides a series of reports from the 1st International Conference on Model Hosts. This first of its kind meeting focused on invertebrate, vertebrate and amoeboid systems used for the study of host-pathogen interactions, virulence and immunity, as well as on the relevance of these pathogenesis systems and mammalian models. Importantly, a common, fundamental set of molecular mechanisms is employed by a significant number of microbial pathogens against a widely divergent array of metazoan hosts. Moreover, the evolutionarily conserved immune responses of these model hosts have contributed important insights to our understanding of the innate immune response of mammals. This book provides a series of reports from the 1st International Conference on Model Hosts. This first of its kind meeting focused on invertebrate, vertebrate and amoeboid systems used for the study of host-pathogen interactions, virulence and immunity, as well as on the relevance of these pathogenesis systems and mammalian models. Importantly, a common, fundamental set of molecular mechanisms is employed by a significant number of microbial pathogens against a widely divergent array of metazoan hosts. Moreover, the evolutionarily conserved immune responses of these model hosts have contributed important insights to our understanding of the innate immune response of mammals.
Author: Alexandra C. Brand Publisher: Humana Press ISBN: 9781493959044 Category : Science Languages : en Pages : 597
Book Description
Microbiologists, medical mycologists, immunologists, and biochemists are increasingly working together to focus on the processes involved in the progression and treatment of fungal disease. Host-Fungus Interactions: Methods and Protocols is designed for research scientists who are involved in this work and interested in undertaking new or comparative studies of interactions between the mammalian host and clinically important fungal pathogens. Aiming to combine approaches for reverse genetics in pathogenic fungi with methods for their application in in vitro and in vivo models of disease, the book includes methods for the culture and genetic manipulation of the primary fungal pathogens and the opportunistic pathogens, as well as methods for investigating host-fungus interactions in model systems. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Host-Fungus Interactions: Methods and Protocols describes available molecular methods and fungal infection models in great detail in order to encourage researchers to try new approaches to investigating host-fungus interactions with added levels of confidence.
Author: Marcela C. Pagano Publisher: Springer ISBN: 3319243551 Category : Science Languages : en Pages : 149
Book Description
Recent Advances on Mycorrhizal Fungi integrates work done by pre-eminent scientists, academics, and researchers dedicated to the study of mycorrhizas in laboratories around the world. The main aim of this book is to compile the information related to mycorrhizas advancement and their applications. First, an overview of the recent advances in mycorrhizal fungi is fully examined. Then, researchers from different countries address issues related to semiarid, xeric, and agro-ecosystems. A greater understanding of the ecology of this type of fungi will underpin efforts to provide new strategies for agriculture production systems and environmental solutions. Finally, relevant topics such as plant stress and ecological succession with regard to mycorrhizal symbioses are discussed. This book will be useful to those who work with mycorrhizas and important for academic and research teams, as well as to teachers, students, professionals and farmers. This information will be a key foundation to decision-makers worldwide and also for conservationists and ecologists.
Author: Vishukumar Aimanianda Publisher: Frontiers Media SA ISBN: 2889660206 Category : Medical Languages : en Pages : 108
Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author: Elaine Bignell Publisher: Humana ISBN: 9781071611814 Category : Science Languages : en Pages : 242
Book Description
This volume provides readers with essential protocols for dissecting the host-fungus interaction, and engages researchers in study of mammalian disease. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Host-Fungal Interactions: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Author: Joseph Heitman Publisher: John Wiley & Sons ISBN: 1555819583 Category : Medical Languages : en Pages : 1136
Book Description
Fungi research and knowledge grew rapidly following recent advances in genetics and genomics. This book synthesizes new knowledge with existing information to stimulate new scientific questions and propel fungal scientists on to the next stages of research. This book is a comprehensive guide on fungi, environmental sensing, genetics, genomics, interactions with microbes, plants, insects, and humans, technological applications, and natural product development.
Author: Michael J. Carlile Publisher: Gulf Professional Publishing ISBN: 0127384464 Category : Science Languages : en Pages : 407
Book Description
This new edition of The Fungi provides a comprehensive introduction to the importance of fungi in the natural world and in practical applications, from a microbiological perspective.
Author: Pankaj Kumar Chaurasia Publisher: ISBN: 9781536171976 Category : Fungi Languages : en Pages : 442
Book Description
Fungi are the renowned eukaryotic organisms. They are heterotrophs like animals, plants and most of the bacteria and studied under the separate branch of science âMycology'. They are abundantly found worldwide as yeasts, moulds, mushrooms etc. Due to the discovery of the different types of fungi, their working styles, habitats, their growing style, culture, sources and optimum locality, fungi have been classified separately from the other eukaryotes like animal and plants. In modern time, there are a number of diseases known which have been caused by fungi but many more significant and useful functions of them are also known and well discovered. Their various positive roles in medicines, remediation, food industries, agriculture, paper and pulp industries, chemical industries, biological researches etc. make them highly significant objectives for researchers and scientists. They also secrete a number of biologically valuable enzymes which further enhance their utility in the field of biotechnology. Their worldwide distributions make them easily available for the research. A number of researches in the field of fungal biotechnology are currently running in order to explore their momentous properties related to their nutraceutical and pharmaceutical values. In this regard, the deep study of their detailed properties, sources, culture, secretion of enzymes, isolation techniques, characterization, kinetics etc. are highly required. Handy nature, very easy language, scientific writing style and advanced research materials of this book make this interesting and highly helpful for the readers and researchers of the field of life sciences, biochemistry and biotechnology to conduct their research. Students of undergraduate and post graduate courses of life sciences/biochemistry/biotechnology will also highly benefit from this book. This book has recent, descriptive as well as up to date information on the recent developments in the world of fungi in the form 17 chapters (divided in two sections: section A and section B) prepared by admirable scientific collaborations. Each chapter has been written by worldwide eminent experts of their scientific research fields. This book covered several valuable and promising topics: (i) Diversity, distribution and classification of fungi. (ii) Isolation, identification and characterization of fungi. (iii) Study of the fungal culture, growth, production, optimization etc. (iv) Rhizospheric fungi, endophytic fungi, lichens, pathogens and secondary metabolites. (v) Fungal properties and applications, biologically potential mushrooms, nutraceutical applications, pharmaceutical applications and bioconversions of wastes materials etc. (vi) Secretion of the different enzymes from fungi (vii) Fungal enzymes, their purification, characterization, kinetics, properties and applications in the field of biotechnology.
Author: Attila Gacser
Author: Attila Gacser
Author: 
Author: Eleftherios Mylonakis
Author: Alexandra C. Brand
Author: Marcela C. Pagano
Author: Vishukumar Aimanianda
Author: Elaine Bignell
Author: Joseph Heitman
Author: Michael J. Carlile
Author: Pankaj Kumar Chaurasia