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Radiotherapy and Clinical Radiobiology of Head and Neck Cancer

Radiotherapy and Clinical Radiobiology of Head and Neck Cancer PDF Author: Loredana G. Marcu
Publisher: CRC Press
ISBN: 135100199X
Category : Science
Languages : en
Pages : 220

Book Description
Common factors that lead to treatment failure in head and neck cancer are the lack of tumour oxygenation, the accelerated division of cancer cells during treatment, and radioresistance. These tumour-related challenges and possible ways to overcome them are covered in this book, authored by three medical physicists and a clinical oncologist who explain how different radiobiological findings have led to the development of various treatment techniques for head and neck cancer. Novel treatment techniques as supported by current scientific evidence are comprehensively explored, as well as the major challenges that arise in the retreatment of patients who have already undergone a form of radiotherapy for primary head and neck cancer. Features: Uses an interdisciplinary approach, encompassing clinical aspects of radiotherapy, radiation biology, and medical physics Applies content by relating all radiobiological characteristics to their respective clinical implications Explains the radiobiological rationale for all previous and current clinical trials for head and neck cancer

Radiotherapy and Clinical Radiobiology of Head and Neck Cancer

Radiotherapy and Clinical Radiobiology of Head and Neck Cancer PDF Author: Loredana G. Marcu
Publisher: CRC Press
ISBN: 135100199X
Category : Science
Languages : en
Pages : 220

Book Description
Common factors that lead to treatment failure in head and neck cancer are the lack of tumour oxygenation, the accelerated division of cancer cells during treatment, and radioresistance. These tumour-related challenges and possible ways to overcome them are covered in this book, authored by three medical physicists and a clinical oncologist who explain how different radiobiological findings have led to the development of various treatment techniques for head and neck cancer. Novel treatment techniques as supported by current scientific evidence are comprehensively explored, as well as the major challenges that arise in the retreatment of patients who have already undergone a form of radiotherapy for primary head and neck cancer. Features: Uses an interdisciplinary approach, encompassing clinical aspects of radiotherapy, radiation biology, and medical physics Applies content by relating all radiobiological characteristics to their respective clinical implications Explains the radiobiological rationale for all previous and current clinical trials for head and neck cancer

Radiotherapy for Head and Neck Cancers

Radiotherapy for Head and Neck Cancers PDF Author: K. Kian Ang
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781760935
Category : Medical
Languages : en
Pages : 234

Book Description
Long established as a staple reference for all radiation oncologists, Radiotherapy for Head and Neck Cancers: Indications and Techniques is now in its Third Edition. This completely updated edition presents the state-of-the-art protocols currently used at the M.D. Anderson Cancer Center and thoroughly explains the principles, nomenclature, and clinical use of intensity-modulated radiotherapy (IMRT). New full-color illustrations have been added throughout the book. The first section discusses the practical aspects of external beam therapy, brachytherapy, and endocavitary beam therapy and offers guidelines on patient care before and during radiotherapy. The second section provides detailed coverage of site-specific indications and techniques.

Basic Clinical Radiobiology

Basic Clinical Radiobiology PDF Author: Michael C. Joiner
Publisher: CRC Press
ISBN: 0429955391
Category : Medical
Languages : en
Pages : 766

Book Description
Basic Clinical Radiobiology is a concise but comprehensive textbook setting out the essentials of the science and clinical application of radiobiology for those seeking accreditation in radiation oncology, clinical radiation physics, and radiation technology. Fully revised and updated to keep abreast of current developments in radiation biology and radiation oncology, this fifth edition continues to present in an interesting way the biological basis of radiation therapy, discussing the basic principles and significant developments that underlie the latest attempts to improve the radiotherapeutic management of cancer. This new edition is highly illustrated with attractive 2-colour presentation and now includes new chapters on stem cells, tissue response and the convergence of radiotherapy, radiobiology, and physics. It will be invaluable for FRCR (clinical oncology) and equivalent candidates, SpRs (and equivalent) in radiation oncology, practicing radiation oncologists and radiotherapists, as well as radiobiologists and radiotherapy physicists.

Current Topics in Clinical Radiobiology of Tumors

Current Topics in Clinical Radiobiology of Tumors PDF Author: Hans-Peter Beck-Bornholdt
Publisher: Springer Science & Business Media
ISBN: 3642849180
Category : Medical
Languages : en
Pages : 364

Book Description
The impact of basic science radiobiological research is now being recognized of significant importance in clinical radiation oncology. Observations made in the laboratory using animals as'well as tissue culture have led to a better biologic understanding of techniques for altered fractionation, techniques for measuring tumor cell proliferation, the possi bilities and limitations of methods for evaluation of nonrandomized clinical studies in deriving time dose relationships for human tumors as well as a better understanding of repair kinetics in mammalian cells, fractionation sensitivity and the major impact oftechnologies to improve local/regional control with the subsequent impact on survival. These findings have led to changes in treatment schedules and have led to further close cooperation among the radiation oncologists and radiation biologists. Well support research efforts in radiation biology have a major and significant impact on the clinical care of the cancer patient. Studies that originated in the laboratory are now finding their way into clinical practice resulting in better local and regional control and improved number of patients surviving without disease.

Head and Neck Cancer

Head and Neck Cancer PDF Author: Dwight E. Heron, MD
Publisher: Demos Medical Publishing
ISBN: 1936287366
Category : Medical
Languages : en
Pages : 187

Book Description
" This issue of Radiation Medicine Rounds examines the latest advances in the use of radiation medicine in treatment of head and neck cancer. Head and neck cancer treatment has undergone major change over the course of the past few years and Head and Neck Cancer addresses current best practices in the light of the most recent evidence. All of the chapters are written by international experts in the field, address the common clinical scenarios in head and neck cancer and are multidisciplinary in scope. Chapters examining health services in head and neck cancer as well as factors influencing clinical decisions round out the coverage. Radiation Medicine Rounds features : In-depth, up-to-date expert reviews and analysis of major new developments in all areas of Radiation Medicine Each issue edited by an authority in that subject area Each issue focused on a single major topic in Radiation Medicine, providing coverage of advances in radiation science, radiation medicine technology, radiation medicine practice, and assessment of recent quality and outcome studies Series Description: Radiation Medicine Rounds is a review series providing a thorough analysis of new scientific, technologic, and clinical advances in all areas of radiation medicine. There will be an emphasis throughout on multidisciplinary approaches to the specialty, as well as an emphasis on quality and outcomes analysis. The goal is to provide authoritative, thorough assessment of a wide range of ""hot topics"" and emerging new data for the entire specialty of radiation medicine. "

Basic Clinical Radiobiology Fourth Edition

Basic Clinical Radiobiology Fourth Edition PDF Author: Michael C. Joiner
Publisher: CRC Press
ISBN: 0340929669
Category : Medical
Languages : en
Pages : 392

Book Description
This concise but comprehensive textbook sets out the essentials of the science and clinical application of radiobiology for those seeking accreditation in radiation oncology, clinical radiation physics and radiation technology. Fully revised and updated to keep abreast of current developments in radiation biology and radiation oncology, the fourth edition continues to present in an interesting way the biological basis of radiation therapy, discussing the basic principles and significant developments that underlie the latest attempts to improve the radiotherapeutic management of cancer. New topics for the fourth edition include chapters on the mechanisms of cell death, biological response modifiers, and biological image guided radiotherapy, with major revisions to sections on the molecular basis of the radiation response, tumour hypoxia and the dose-rate effect. A variety of new authors have contributed to this revision, who, together with the new Editorial team, have used their significant international teaching experience to ensure the content remains clear and comprehensive, and as valuable to the trainee as it is to the established radiation oncologist. With the fourth edition we will see the most radical change so far - as Professor Gordon Steel has retired as Editor and has been replaced by Bert van der Kogel, the current current course director for the above-mentioned course, plus Michael Joiner, who is the head of the Radiation Biology Program at the Wayne State University and is the Associate Editor of the International Journal of Radiation Biology.

Radiation Therapy of Head and Neck Cancer

Radiation Therapy of Head and Neck Cancer PDF Author: George E. Laramore
Publisher: Springer Science & Business Media
ISBN: 3642835015
Category : Medical
Languages : en
Pages : 399

Book Description
The contemporary management of patients with cancers of the head and neck is under careful scrutiny and major changes are being introduced in order to improve the potenti al not only for long-term control but also for less in the way of disfiguring and distres sing complications associated with the treatment programs. In 1988, the American Cancer Society estimates that there will be 42400 new cases of malignant tumors of the head and neck diagnosed with 12 850 deaths. In general, the prognosis for patients with malignant tumors of the head and neck re gion depends upon the site of origin, the local and regional extent of the tumor, the Kar nofsky status of the patient as well as the patient's general medical condition. The poten tial for cure for early stage tumors is extremely high particularly for those lesions involving the vocal cord, oral cavity, and the anterior two-thirds of the tongue. Major advances have been made in the management of head and neck cancer by the innovative utilization of surgery with radiation therapy. Small tumors can be cured by ei ther surgery or radiation therapy with equally good results. However, far advanced tu mors are more complicated and more difficult to cure requiring combined, integrated, multimodal programs of management. Therefore, the previously general poor prognosis for advanced tumors is becoming better with more aggressive treatment regimens.

Clinical Radiation Oncology

Clinical Radiation Oncology PDF Author: William Small, Jr.
Publisher: John Wiley & Sons
ISBN: 1119341213
Category : Medical
Languages : en
Pages : 944

Book Description
This fully updated and enhanced third edition offers a highly practical, application-based review of the biological basis of radiation oncology and the clinical efficacy of radiation therapy. Revised edition of the classic reference in radiation oncology from Dr. C.C. Wang, whose practical approach to clinical application was legendary Includes the latest developments in the field: intensity modulated radiation therapy (IMRT), image guided radiation therapy, and particle beam therapy Includes two brand new chapters Palliative Radiotherapy, and Statistics in Radiation Oncology Features a vibrant and extremely comprehensive head and neck section Provides immediately applicable treatment algorithms for each tumor

Intensity Modulated Radiation Therapy for Head and Neck Cancer

Intensity Modulated Radiation Therapy for Head and Neck Cancer PDF Author: K. S. Clifford Chao
Publisher: Lippincott Raven
ISBN:
Category : Medical
Languages : en
Pages : 200

Book Description
The first clinical book on the hottest topic in radiation oncology, this timely teaching text offers step-by-step guidance in use of IMRT for cancers at each subsite of the head and neck. The book's high-end content gives readers the clinical decision-making expertise and technical proficiency to incorporate this state-of-the-art radiation treatment technique into practice. Unique to this text is the site-specific instruction on target determination and delineation, to ensure adequate treatment of the tumor target while sparing adjacent normal tissue. More than 250 detailed full-color and black-and-white illustrations clarify each step in clinical implementations of head and neck cancer treatment, especially IMRT. The book provides a concise, pertinent overview of the natural course, lymph node spread, diagnostic criteria, and therapeutic options for each head and neck cancer subsite. Numerous tables provide extensive summaries of the IMRT literature. Figures with succinct explanatory text demonstrate the patterns of direct tumor extension and nodal metastasis with which target volumes are determined and delineated. Clinical outcomes for patients treated with IMRT and with conventional techniques are also included.

Radiotherapy for Head and Neck Cancers

Radiotherapy for Head and Neck Cancers PDF Author: K. Kian Ang
Publisher: Lea & Febiger
ISBN:
Category : Medical
Languages : en
Pages : 160

Book Description