Medical Isotope Production Without Highly Enriched Uranium

Medical Isotope Production Without Highly Enriched Uranium PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309130395
Category : Medical
Languages : en
Pages : 220

Book Description
This book is the product of a congressionally mandated study to examine the feasibility of eliminating the use of highly enriched uranium (HEU2) in reactor fuel, reactor targets, and medical isotope production facilities. The book focuses primarily on the use of HEU for the production of the medical isotope molybdenum-99 (Mo-99), whose decay product, technetium-99m3 (Tc-99m), is used in the majority of medical diagnostic imaging procedures in the United States, and secondarily on the use of HEU for research and test reactor fuel. The supply of Mo-99 in the U.S. is likely to be unreliable until newer production sources come online. The reliability of the current supply system is an important medical isotope concern; this book concludes that achieving a cost difference of less than 10 percent in facilities that will need to convert from HEU- to LEU-based Mo-99 production is much less important than is reliability of supply.

Setting Up a Radiotherapy Programme

Setting Up a Radiotherapy Programme PDF Author: International Atomic Energy Agency
Publisher:
ISBN: 9789201018076
Category : Medical
Languages : en
Pages : 229

Book Description
This publication provides guidance for designing and implementing radiotherapy programmes, taking into account clinical, medical physics, radiation protection and safety aspects. It reflects current requirements for radiotherapy infrastructure in settings with limited resources. It will be of use to professionals involved in the development, implementation and management of radiotherapy programmes

Energy and Water Development Appropriations for 2008

Energy and Water Development Appropriations for 2008 PDF Author: United States. Congress. House. Committee on Appropriations. Subcommittee on Energy and Water Development
Publisher:
ISBN:
Category : Federal aid to energy development
Languages : en
Pages : 666

Book Description


Comprehensive Nuclear Materials

Comprehensive Nuclear Materials PDF Author:
Publisher: Elsevier
ISBN: 0081028660
Category : Science
Languages : en
Pages : 4871

Book Description
Materials in a nuclear environment are exposed to extreme conditions of radiation, temperature and/or corrosion, and in many cases the combination of these makes the material behavior very different from conventional materials. This is evident for the four major technological challenges the nuclear technology domain is facing currently: (i) long-term operation of existing Generation II nuclear power plants, (ii) the design of the next generation reactors (Generation IV), (iii) the construction of the ITER fusion reactor in Cadarache (France), (iv) and the intermediate and final disposal of nuclear waste. In order to address these challenges, engineers and designers need to know the properties of a wide variety of materials under these conditions and to understand the underlying processes affecting changes in their behavior, in order to assess their performance and to determine the limits of operation. Comprehensive Nuclear Materials, Second Edition, Seven Volume Set provides broad ranging, validated summaries of all the major topics in the field of nuclear material research for fission as well as fusion reactor systems. Attention is given to the fundamental scientific aspects of nuclear materials: fuel and structural materials for fission reactors, waste materials, and materials for fusion reactors. The articles are written at a level that allows undergraduate students to understand the material, while providing active researchers with a ready reference resource of information. Most of the chapters from the first Edition have been revised and updated and a significant number of new topics are covered in completely new material. During the ten years between the two editions, the challenge for applications of nuclear materials has been significantly impacted by world events, public awareness, and technological innovation. Materials play a key role as enablers of new technologies, and we trust that this new edition of Comprehensive Nuclear Materials has captured the key recent developments. Critically reviews the major classes and functions of materials, supporting the selection, assessment, validation and engineering of materials in extreme nuclear environments Comprehensive resource for up-to-date and authoritative information which is not always available elsewhere, even in journals Provides an in-depth treatment of materials modeling and simulation, with a specific focus on nuclear issues Serves as an excellent entry point for students and researchers new to the field

The Supply of Medical Isotopes

The Supply of Medical Isotopes PDF Author:
Publisher:
ISBN: 9789264625099
Category :
Languages : en
Pages : 122

Book Description
This report explores the main reasons behind the unreliable supply of Technetium-99m (Tc-99m) in health-care systems and policy options to address the issue. Tc-99m is used in 85% of nuclear medicine diagnostic scans performed worldwide – around 30 million patient examinations every year. These scans allow diagnoses of diseases in many parts of the human body, including the skeleton, heart and circulatory system, and the brain. Medical isotopes are subject to radioactive decay and have to be delivered just-in-time through a complex supply chain. However, ageing production facilities and a lack of investment have made the supply of Tc-99m unreliable. This report analyses the use and substitutability of Tc-99m in health care, health-care provider payment mechanisms for scans, and the structure of the supply chain. It concludes that the main reasons for unreliable supply are that production is not economically viable and that the structure of the supply chain prevents producers from charging prices that reflect the full costs of production and supply.

Molybdenum-99 for Medical Imaging

Molybdenum-99 for Medical Imaging PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309445310
Category : Medical
Languages : en
Pages : 264

Book Description
The decay product of the medical isotope molybdenum-99 (Mo-99), technetium-99m (Tc-99m), and associated medical isotopes iodine-131 (I-131) and xenon-133 (Xe-133) are used worldwide for medical diagnostic imaging or therapy. The United States consumes about half of the world's supply of Mo-99, but there has been no domestic (i.e., U.S.-based) production of this isotope since the late 1980s. The United States imports Mo-99 for domestic use from Australia, Canada, Europe, and South Africa. Mo-99 and Tc-99m cannot be stockpiled for use because of their short half-lives. Consequently, they must be routinely produced and delivered to medical imaging centers. Almost all Mo-99 for medical use is produced by irradiating highly enriched uranium (HEU) targets in research reactors, several of which are over 50 years old and are approaching the end of their operating lives. Unanticipated and extended shutdowns of some of these old reactors have resulted in severe Mo-99 supply shortages in the United States and other countries. Some of these shortages have disrupted the delivery of medical care. Molybdenum-99 for Medical Imaging examines the production and utilization of Mo-99 and associated medical isotopes, and provides recommendations for medical use.

Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets

Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 030946627X
Category : Medical
Languages : en
Pages : 87

Book Description
Participants of the July 17-18, 2017, symposium titled Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets examined current trends in molybdenum-99 production, prospects for new global supplies, and technical, economic, regulatory, and other considerations for supplying molybdenum-99 to global markets. This publication summarizes the presentations and discussions from the symposium.

On the Horizon

On the Horizon PDF Author: Sarah Minot Asrar
Publisher: Rowman & Littlefield
ISBN: 1442281049
Category : Political Science
Languages : en
Pages : 207

Book Description
The papers included in this volume comprise research from participants in the 2018 Nuclear Scholars Initiative and the Project on Nuclear Issues (PONI) Conference Series. PONI sponsors this research to provide a forum for facilitating new and innovative thinking and to provide a platform for emerging thought leaders across the nuclear enterprise. The papers in this volume span a wide range of technical and policy issues, further discussion in their respective areas, and provide innovative recommendations for pressing challenges. To that end, these papers explore such topics as the impacts of emerging technologies and capabilities, deep-diving on nuclear strategy and national policies, proposing paths forward for addressing proliferation challenges, and enhancing arms control in contentious environments.

Radiation Source Use and Replacement

Radiation Source Use and Replacement PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309110149
Category : Medical
Languages : en
Pages : 232

Book Description
In the United States there are several thousand devices containing high-activity radiation sources licensed for use in areas ranging from medical uses such as cancer therapy to safety uses such as testing of structures and industrial equipment. Those radiation sources are licensed by the U.S. Nuclear Regulatory Commission and state agencies. Concerns have been raised about the safety and security of the radiation sources, particularly amid fears that they could be used to create dirty bombs, or radiological dispersal device (RDD). In response to a request from Congress, the U.S. Nuclear Regulatory Commission asked the National Research Council to conduct a study to review the uses of high-risk radiation sources and the feasibility of replacing them with lower risk alternatives. The study concludes that the U.S. government should consider factors such as potential economic consequences of misuse of the radiation sources into its assessments of risk. Although the committee found that replacements of most sources are possible, it is not economically feasible in some cases. The committee recommends that the U.S. government take steps to in the near term to replace radioactive cesium chloride radiation sources, a potential "dirty bomb" ingredient used in some medical and research equipment, with lower-risk alternatives. The committee further recommends that longer term efforts be undertaken to replace other sources. The book presents a number of options for making those replacements.

Nuclear Terrorism and Global Security

Nuclear Terrorism and Global Security PDF Author: Alan J. Kuperman
Publisher: Routledge
ISBN: 1135105863
Category : Political Science
Languages : en
Pages : 257

Book Description
This book examines the prospects and challenges of a global phase-out of highly enriched uranium—and the risks of this material otherwise being used by terrorists to make atom bombs. Terrorist groups, such as Al Qaeda, have demonstrated repeatedly that they seek to acquire nuclear weapons. Unbeknownst even to many security specialists, tons of bomb-grade uranium are trafficked legally each year for ostensibly peaceful purposes. If terrorists obtained even a tiny fraction of this bomb-grade uranium they could potentially construct a nuclear weapon like the one dropped on Hiroshima that killed tens of thousands. Nuclear experts and policymakers have long known of this danger but – so far – have taken only marginal steps to address it. This volume begins by highlighting the lessons of past successes where bomb-grade uranium commerce has been eliminated, such as from Argentina’s manufacture of medical isotopes. It then explores the major challenges that still lie ahead: for example, Russia’s continued use of highly enriched uranium (HEU) in dozens of nuclear facilities. Each of the book’s thirteen case studies offers advice for reducing HEU in a specific sector. These insights are then amalgamated into nine concrete policy recommendations for U.S. and world leaders to promote a global phase-out of bomb-grade uranium. This book will be of much interest to students of nuclear proliferation, global governance, international relations and security studies.