Quantitative Approaches to Microcirculation PDF Download

Author: Andreas Linninger
Publisher: Springer Nature
ISBN: 3031585194
Category :
Languages : en
Pages : 224

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Author: Giampaolo Niccoli
Publisher: Academic Press
ISBN: 0128133619
Category : Medical
Languages : en
Pages : 401

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Book Description
Coronary Microvascular Obstruction in Acute Myocardial Infarction: From Mechanisms to Treatment provides a comprehensive understanding of the phenomenon of coronary microvascular obstruction (CMVO) that is the main limitation of reperfusion therapies in ST-elevation myocardial infarction. It provides in-depth coverage of the phenomenon of CMVO which heavily affects prognosis by increasing the risk of death and heart failure at follow-up. A first of its kind reference dedicated solely to this topic, it is appropriate for a wide audience, from researchers, to those who aid in the management, prevention and treatment of CMVO. - Provides in-depth coverage of coronary microvascular obstruction (CMVO), spanning research, management, prevention and treatment - Includes the most up-to-date information on CMVO as presented from top experts around the word - Provides access to a companion website with extra material, including tables, additional references and instructional videos - Gives extensive coverage on how to measure CMVO, including in-depth indexes that can be used to detect and quantify the phenomenon

Author: D. Neil Granger
Publisher: Morgan & Claypool Publishers
ISBN: 1615041656
Category : Medical
Languages : en
Pages : 99

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Book Description
The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of the microvasculature (arterioles, capillaries, and venules) exhibit characteristic phenotypic changes during inflammation that appear to be directed toward enhancing the delivery of inflammatory cells to the injured/infected tissue, isolating the region from healthy tissue and the systemic circulation, and setting the stage for tissue repair and regeneration. The best characterized responses of the microcirculation to inflammation include impaired vasomotor function, reduced capillary perfusion, adhesion of leukocytes and platelets, activation of the coagulation cascade, and enhanced thrombosis, increased vascular permeability, and an increase in the rate of proliferation of blood and lymphatic vessels. A variety of cells that normally circulate in blood (leukocytes, platelets) or reside within the vessel wall (endothelial cells, pericytes) or in the perivascular space (mast cells, macrophages) are activated in response to inflammation. The activation products and chemical mediators released from these cells act through different well-characterized signaling pathways to induce the phenotypic changes in microvessel function that accompany inflammation. Drugs that target a specific microvascular response to inflammation, such as leukocyte-endothelial cell adhesion or angiogenesis, have shown promise in both the preclinical and clinical studies of inflammatory disease. Future research efforts in this area will likely identify new avenues for therapeutic intervention in inflammation. Table of Contents: Introduction / Historical Perspectives / Anatomical Considerations / Impaired Vasomotor Responses / Capillary Perfusion / Angiogenesis / Leukocyte-Endothelial Cell Adhesion / Platelet-Vessel Wall Interactions / Coagulation and Thrombosis / Endothelial Barrier Dysfunction / Epilogue / References

Author: David Shepro
Publisher: Elsevier
ISBN: 0126395101
Category : Medical
Languages : en
Pages : 1353

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Book Description
The microvasculature refers to the smallest blood vessels, arterial and venous, that nurture the tissues of each organ. Apart from transport, they also contribute to the systematic regulation of the body. In everyday terminology, the microcirculation is "where the action is." Microcirculation is directly involved in such disease states as Alzheimers, inflammation, tumor growth, diabetic retinopathy, and wound healing- plus cardiovascular fitness is directly related to the formation of new capillaries in large muscles. Microvascular Research is the first book devoted exclusively to this vital systemic component of the cardiovascular system and provides up to date mini-reviews of normal functions and clinical states. The contributing authors are senior scientists with international reputation in their given disciplines. This two-volume set is a broad, interdisciplinary work that encompasses basic research and clinical applications equally. * Broad coverage of both basic and clinical aspects of microvasculature research * Contains 167 chapters from over 300 international authors * Each chapter includes key figures and annotated references

Author: Michael R. Pinsky
Publisher: Springer Science & Business Media
ISBN: 9783540229865
Category : Medical
Languages : en
Pages : 442

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Book Description
This is the newest volume in the softcover series "Update in Intensive Care Medicine". It takes a novel, practical approach to analyzing hemodynamic monitoring, focusing on the patient and outcomes based on disease, treatment options and relevance of monitoring to direct patient care. It will rapidly become a classic in the approach to patient monitoring and management during critical illness.

Author: Michael R. Pinsky
Publisher: Springer Science & Business Media
ISBN: 3642282709
Category : Medical
Languages : en
Pages : 430

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Book Description
The two previous editions of Applied Physiology in Intensive Care Medicine proved extremely successful, and the book has now been revised and split into two volumes to enhance ease of use. This first volume comprises three elements -- "physiological notes," “technical notes,” and seminal studies. The physiological notes concisely and clearly capture the essence of the physiological perspectives underpinning our understanding of disease and response to therapy. The technical notes then succinctly explain some of the basics of “how to” in this technology-centered field of critical care medicine. Finally, a number of seminal studies are provided on diverse topics in intensive care. Applied Physiology in Intensive Care, written by some of the most renowned experts in the field, is an up-to-date compendium of practical bedside knowledge that will serve the clinician as an invaluable reference source on key issues regularly confronted in everyday practice.

Author: A. Gullo
Publisher: Springer Science & Business Media
ISBN: 8847004071
Category : Medical
Languages : en
Pages : 844

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Book Description
Progress in the field of medicine over the last 50 years has led to important results for society, both in terms of prevention and in the treatment of single or variously associated pathologies. The main objective of modern medicine has been the acquisition of increased skills and highly specialised knowledge in the various disciplines. At the same time, there has been a progressive multidisciplinary and multi-professional interest in acute disease conditions that place the patient in potential or real life-threatening situations. The state of the art of intensive medicine comprises a wide range of sophisticated interventions and collaboration between different medical disciplines, both of which give the patient access to the most advanced forms of treatment that are currently available.

Author: Juan Carlos Kaski
Publisher: Springer Science & Business Media
ISBN: 144714838X
Category : Medical
Languages : en
Pages : 351

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Book Description
Written by leading authorities in the field, Chest Pain with Normal Coronary Arteries comprehensively reviews the clinical presentation and the pathogenesis of the condition, as well as its management. This book provides a practical tool for the clinician and a bank of information and new ideas for research scientists and clinical researchers interested in understanding the causes and mechanisms of chest pain with normal coronary arteries. Whether the pain be of gastroenterologic, cardiac or endocrine in origin, the book focuses on effective diagnosis, treatment and management of different pathologies in patients. Chest Pain with Normal Coronary Arteries is an essential read for all clinicians involved in managing patients with chest pain, and those that should be aware of non-cardiac chest pain.

Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1364

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Author: Silvia Aguiar Rosa
Publisher: Principia Editora
ISBN: 9897163255
Category : Medical
Languages : en
Pages : 106

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Book Description
The increasing awareness of coronary microvascular dysfunction through the broad spectrum of car-diovascular disease makes this pathophysiological feature an important aspect to study in clinical practice. A multimodality approach, including echocardiography, cardiovascular magnetic resonance, PET and cardiac catheterization, allows a holistic view into microcirculation in each entity, and contri-butes for a better understanding of the pathophysiology.The search for coronary microvascular dysfunction may potentially change the management of the patient and treatment approach, with recognized prognostic impact. This book aims to review the principal aspects of coronary microvascu-lar dysfunction, from the pathophysiology, to imaging, clinical relevance and treatment.