Author: P. D. Sethi
Publisher:
ISBN: 9788123905600
Category : Drugs
Languages : en
Pages : 692
Book Description
Quantitative Analysis of Drugs in Pharmaceutical Formulations, 3e
Author: P. D. Sethi
Publisher:
ISBN: 9788123905600
Category : Drugs
Languages : en
Pages : 692
Book Description
Publisher:
ISBN: 9788123905600
Category : Drugs
Languages : en
Pages : 692
Book Description
Quantitative Analysis of Drugs in Pharmaceutical Formulations
Author: Prabhu Dayal Sethi
Publisher:
ISBN: 9788190000505
Category :
Languages : en
Pages : 478
Book Description
Publisher:
ISBN: 9788190000505
Category :
Languages : en
Pages : 478
Book Description
The Quantitative Analysis of Drugs
Author: Donald Clarence. Garratt
Publisher: Springer Science & Business Media
ISBN: 1461333806
Category : Science
Languages : en
Pages : 937
Book Description
General Monographs, Alphabetically Arranged and Consisting of Methods for Quantitative Determination of the Substance, its Salts, and Preparations of Which it is a Principal Con- Stituent.- Synthetic Organic Compounds, Methods for Determination of Substances not Included in the General Monographs.- Essential Oils.- Oils, Fats and Waxes.- Appendices.- I. Determination of Alcohol Content.- II. Complexometric Titrations.- III. Non-aqueous Titrations.- IV. The Oxygen-Flask Combustion Technique.- V. Determination of Water.- VI. Extraneous Matter in Food and Drugs.- VII. Microbiological Assays.- VII.
Publisher: Springer Science & Business Media
ISBN: 1461333806
Category : Science
Languages : en
Pages : 937
Book Description
General Monographs, Alphabetically Arranged and Consisting of Methods for Quantitative Determination of the Substance, its Salts, and Preparations of Which it is a Principal Con- Stituent.- Synthetic Organic Compounds, Methods for Determination of Substances not Included in the General Monographs.- Essential Oils.- Oils, Fats and Waxes.- Appendices.- I. Determination of Alcohol Content.- II. Complexometric Titrations.- III. Non-aqueous Titrations.- IV. The Oxygen-Flask Combustion Technique.- V. Determination of Water.- VI. Extraneous Matter in Food and Drugs.- VII. Microbiological Assays.- VII.
A Comparative Study of the Quantitative Analysis of Barbiturates and Related Drugs in Pharmaceutical Formulations by Nuclear Magnetic Resonance and High Pressure Liquid Chromatography
Author: Nasreen Banu Zaidi
Publisher:
ISBN:
Category : Barbiturates
Languages : en
Pages : 108
Book Description
Publisher:
ISBN:
Category : Barbiturates
Languages : en
Pages : 108
Book Description
Identification and Determination of Impurities in Drugs
Author: S. Görög
Publisher: Elsevier
ISBN: 0080534406
Category : Science
Languages : en
Pages : 773
Book Description
Impurity profiling is the common name of a group of analytical activities, the aim of which is the detection, identification/structure elucidation and quantitative determination of organic and inorganic impurities, as well as residual solvents in bulk drugs and pharmaceutical formulations. Since this is the best way to characterise the quality and stability of bulk drugs and pharmaceutical formulations, this is the core activity in modern drug analysis.Due to the very rapid development of the analytical methodologies available for this purpose and the similarly rapid increase of the demands as regards the purity of drugs it is an important task to give a summary of the problems and the various possibilities offered by modern analytical chemistry for their solution. That is the aim of this book.The book is methodology-oriented. In the first chapter some important aspects of the background of impurity-related analytical studies (toxicological, pharmacopoeial aspects, the characterisation of the sources of impurities and the role of impurity profiling in various fields of drug research, production and therapeutic use) are summarised. Chapter two deals with related organic impurities, the strategies for impurity profiling, the use of chromatographic and related separation methods, spectroscopic, and hyphenated techniques. The subject of the third chapter is the identification and determination of residual solvents. The determination of inorganic impurities is discussed in chapter four. The special problems of degradation products as impurities are dealt with in chapter five. A separate chapter has been compiled to deal with one of the most up-to-date problems in contemporary pharmaceutical analysis, the estimation of enantiomeric purity of chiral drugs. Chapter seven is devoted to various approaches to solve the problem of polymorphic modifications as impurities. Since in the broader sense of the word the microbiological purity of drugs and drug products also belongs to this circle, the most important information from this field is summarised in chapter eight. After the mainly methodology-oriented chapters, the final one concentrates on four groups of drugs (peptides, biotechnological products, antibiotics and steroids) in order to demonstrate the use of the methods described earlier.
Publisher: Elsevier
ISBN: 0080534406
Category : Science
Languages : en
Pages : 773
Book Description
Impurity profiling is the common name of a group of analytical activities, the aim of which is the detection, identification/structure elucidation and quantitative determination of organic and inorganic impurities, as well as residual solvents in bulk drugs and pharmaceutical formulations. Since this is the best way to characterise the quality and stability of bulk drugs and pharmaceutical formulations, this is the core activity in modern drug analysis.Due to the very rapid development of the analytical methodologies available for this purpose and the similarly rapid increase of the demands as regards the purity of drugs it is an important task to give a summary of the problems and the various possibilities offered by modern analytical chemistry for their solution. That is the aim of this book.The book is methodology-oriented. In the first chapter some important aspects of the background of impurity-related analytical studies (toxicological, pharmacopoeial aspects, the characterisation of the sources of impurities and the role of impurity profiling in various fields of drug research, production and therapeutic use) are summarised. Chapter two deals with related organic impurities, the strategies for impurity profiling, the use of chromatographic and related separation methods, spectroscopic, and hyphenated techniques. The subject of the third chapter is the identification and determination of residual solvents. The determination of inorganic impurities is discussed in chapter four. The special problems of degradation products as impurities are dealt with in chapter five. A separate chapter has been compiled to deal with one of the most up-to-date problems in contemporary pharmaceutical analysis, the estimation of enantiomeric purity of chiral drugs. Chapter seven is devoted to various approaches to solve the problem of polymorphic modifications as impurities. Since in the broader sense of the word the microbiological purity of drugs and drug products also belongs to this circle, the most important information from this field is summarised in chapter eight. After the mainly methodology-oriented chapters, the final one concentrates on four groups of drugs (peptides, biotechnological products, antibiotics and steroids) in order to demonstrate the use of the methods described earlier.
Quantitative Methods in Pharmaceutical Research and Development
Author: Olga V. Marchenko
Publisher: Springer Nature
ISBN: 3030485552
Category : Medical
Languages : en
Pages : 445
Book Description
This contributed volume presents an overview of concepts, methods, and applications used in several quantitative areas of drug research, development, and marketing. Chapters bring together the theories and applications of various disciplines, allowing readers to learn more about quantitative fields, and to better recognize the differences between them. Because it provides a thorough overview, this will serve as a self-contained resource for readers interested in the pharmaceutical industry, and the quantitative methods that serve as its foundation. Specific disciplines covered include: Biostatistics Pharmacometrics Genomics Bioinformatics Pharmacoepidemiology Commercial analytics Operational analytics Quantitative Methods in Pharmaceutical Research and Development is ideal for undergraduate students interested in learning about real-world applications of quantitative methods, and the potential career options open to them. It will also be of interest to experts working in these areas.
Publisher: Springer Nature
ISBN: 3030485552
Category : Medical
Languages : en
Pages : 445
Book Description
This contributed volume presents an overview of concepts, methods, and applications used in several quantitative areas of drug research, development, and marketing. Chapters bring together the theories and applications of various disciplines, allowing readers to learn more about quantitative fields, and to better recognize the differences between them. Because it provides a thorough overview, this will serve as a self-contained resource for readers interested in the pharmaceutical industry, and the quantitative methods that serve as its foundation. Specific disciplines covered include: Biostatistics Pharmacometrics Genomics Bioinformatics Pharmacoepidemiology Commercial analytics Operational analytics Quantitative Methods in Pharmaceutical Research and Development is ideal for undergraduate students interested in learning about real-world applications of quantitative methods, and the potential career options open to them. It will also be of interest to experts working in these areas.
The Quantitative Analysis of Drugs
Author: Donald Clarence Garratt
Publisher:
ISBN: 9781461333814
Category :
Languages : en
Pages : 944
Book Description
Publisher:
ISBN: 9781461333814
Category :
Languages : en
Pages : 944
Book Description
Sethi's Quantitative Analysis of Pharmaceutical Formulations
Author: P. D. Sethi
Publisher: CBS Publishers & Distributors Pvt Limited, India
ISBN: 9788123921877
Category : Medical
Languages : en
Pages :
Book Description
Publisher: CBS Publishers & Distributors Pvt Limited, India
ISBN: 9788123921877
Category : Medical
Languages : en
Pages :
Book Description
Sethi's Hplc High Performance Liquid Chromatography: Quantitative Analysis Of Pharmaceutical Formulations, Vol. 3 (hb)
Author: Rajat Sethi
Publisher:
ISBN: 9788123918693
Category :
Languages : en
Pages : 493
Book Description
Publisher:
ISBN: 9788123918693
Category :
Languages : en
Pages : 493
Book Description
Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery
Author: Gus R. Rosania
Publisher: Humana
ISBN: 9781071612491
Category : Medical
Languages : en
Pages : 453
Book Description
This thorough book explores some of the most important methods and concepts affecting the quantitative analysis of the transport, targeting, and disposition of chemicals within cells, which in turn impact the macroscopic pharmacokinetics of chemical agents in the whole organism. The first half of the volume focuses on small organic molecules with drug-like characteristics, while the second half delves into the cellular pharmacokinetics of biologics and other macromolecules, including peptide therapeutics, cyclotides, antibodies, as well as nanoparticles, thus creating a comprehensive treatise that approaches cellular pharmacokinetics from the different perspectives of pharmaceutical scientists, chemical biologists, medicinal chemists, and protein engineers dealing with very different chemical agents spanning a wide range of sizes, physicochemical properties, and targeting mechanisms. Written for the Methods in Pharmacology and Toxicology series, chapters provide the kind of key detail and expert implementation advice that leads to excellent results in the lab. Synthetic biologists, biophysicists, and bioengineers are amongst the long list of scientists who could benefit from reading this book or from using it as a textbook. Authoritative and practical, Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery builds on a long history of drug development and the adding of quantitative methods at the cellular scale in order to inspire new approaches to drug development that are better able to take advantage of phenomena such as soluble-to-insoluble phase transitions or bispecific targeting, which could ultimately be exploited for the development of more effective drug delivery systems and therapeutic agents.
Publisher: Humana
ISBN: 9781071612491
Category : Medical
Languages : en
Pages : 453
Book Description
This thorough book explores some of the most important methods and concepts affecting the quantitative analysis of the transport, targeting, and disposition of chemicals within cells, which in turn impact the macroscopic pharmacokinetics of chemical agents in the whole organism. The first half of the volume focuses on small organic molecules with drug-like characteristics, while the second half delves into the cellular pharmacokinetics of biologics and other macromolecules, including peptide therapeutics, cyclotides, antibodies, as well as nanoparticles, thus creating a comprehensive treatise that approaches cellular pharmacokinetics from the different perspectives of pharmaceutical scientists, chemical biologists, medicinal chemists, and protein engineers dealing with very different chemical agents spanning a wide range of sizes, physicochemical properties, and targeting mechanisms. Written for the Methods in Pharmacology and Toxicology series, chapters provide the kind of key detail and expert implementation advice that leads to excellent results in the lab. Synthetic biologists, biophysicists, and bioengineers are amongst the long list of scientists who could benefit from reading this book or from using it as a textbook. Authoritative and practical, Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery builds on a long history of drug development and the adding of quantitative methods at the cellular scale in order to inspire new approaches to drug development that are better able to take advantage of phenomena such as soluble-to-insoluble phase transitions or bispecific targeting, which could ultimately be exploited for the development of more effective drug delivery systems and therapeutic agents.