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Author: Shuang-Qing Zhang Publisher: Nova Science Publishers ISBN: 9781634844949 Category : Natural products Languages : en Pages : 0
Book Description
Natural medicines are derived from natural sources such as plants, animals and/or mineral origins. The use of traditional natural products is an empirical healthcare system based on thousands of years of human experience. Over the past few decades, quality control and safety evaluation methods for natural products, though sophisticated and technologically advanced, still lack comprehensiveness and practicability to some extent. Generally, those methods fully satisfy the modern scientific requirements for extraction, identification, purity, quality and pharmacological effects in the assessment of chemical drugs. However, they are not suitable for handling the complex chemical characteristics of natural products. Therefore, a better understanding of the basic properties of natural medicines and advanced chemical, pharmacological and biological techniques would facilitate the application of the natural products in public health. The purpose of this book is to address the issues mentioned above and present related solutions. The book covers the below topics: Advanced analytical technologies in the application of the natural medicines (eg: mass spectrometry, gas or liquid chromatography, and NMR); Recent advances in biochemistry research of natural medicines (e.g. gene expression microarray, tissue microarray, and chromatin-precipitation assay); Innovations in analytical chemistry of natural products; Quality control and safety evaluation of traditional medical material and finished products; Detection of low quality and adulterants of natural product; Identification of the plant by various analytical techniques; Regulations and management of natural products from foreign countries; Novel cell-based models used for the high-throughput screening for drug discovery in natural products; Pharmacological effects of natural products in vitro and in vivo; Advanced modeling techniques used in pharamcokinetic and pharmacodynamic properties of natural products (eg: Pharsight WINNONLIN, Simcyp, and Gastroplus).
Author: Shuang-Qing Zhang Publisher: Nova Science Publishers ISBN: 9781634844949 Category : Natural products Languages : en Pages : 0
Book Description
Natural medicines are derived from natural sources such as plants, animals and/or mineral origins. The use of traditional natural products is an empirical healthcare system based on thousands of years of human experience. Over the past few decades, quality control and safety evaluation methods for natural products, though sophisticated and technologically advanced, still lack comprehensiveness and practicability to some extent. Generally, those methods fully satisfy the modern scientific requirements for extraction, identification, purity, quality and pharmacological effects in the assessment of chemical drugs. However, they are not suitable for handling the complex chemical characteristics of natural products. Therefore, a better understanding of the basic properties of natural medicines and advanced chemical, pharmacological and biological techniques would facilitate the application of the natural products in public health. The purpose of this book is to address the issues mentioned above and present related solutions. The book covers the below topics: Advanced analytical technologies in the application of the natural medicines (eg: mass spectrometry, gas or liquid chromatography, and NMR); Recent advances in biochemistry research of natural medicines (e.g. gene expression microarray, tissue microarray, and chromatin-precipitation assay); Innovations in analytical chemistry of natural products; Quality control and safety evaluation of traditional medical material and finished products; Detection of low quality and adulterants of natural product; Identification of the plant by various analytical techniques; Regulations and management of natural products from foreign countries; Novel cell-based models used for the high-throughput screening for drug discovery in natural products; Pharmacological effects of natural products in vitro and in vivo; Advanced modeling techniques used in pharamcokinetic and pharmacodynamic properties of natural products (eg: Pharsight WINNONLIN, Simcyp, and Gastroplus).
Author: Pulok K. Mukherjee Publisher: Elsevier ISBN: 0128133988 Category : Science Languages : en Pages : 784
Book Description
Quality Control and Evaluation of Herbal Drugs brings together current thinking and practices for evaluation of natural products and traditional medicines. The use of herbal medicine in therapeutics is on the rise in both developed and developing countries and this book facilitates the necessary development of quality standards for these medicines.This book elucidates on various challenges and opportunities for quality evaluation of herbal drugs with several integrated approaches including metabolomics, chemoprofiling, marker analysis, stability testing, good practices for manufacturing, clinical aspects, Ethnopharmacology and Ethnomedicine inspired drug development. Written by Prof. Pulok K Mukherjee, a leader in this field; the book highlights on various methods, techniques and approaches for evaluating the purity, quality, safety and efficacy of herbal drugs. Particular attention is paid to methods that assess these drugs’ activity, the compounds responsible and their underlying mechanisms of action. The book describes the quality control parameters followed in India and other countries, including Japan, China, Bangladesh, and other Asian countries, as well as the regulatory profiles of the European Union and North America. This book will be useful in bio-prospecting of natural products and traditional medicine-inspired drug discovery and development. Provides new information on the research and development of natural remedies - essential reading on the study and use of natural resources for preventative or healing purposes Brings together current thinking and practices in quality control and standardization of herbal drugs highlighting several integrated approaches for metabolomics, chemo-profiling and marker analysis Aids in developing knowledge of various techniques including macroscopy, microscopy, HPTLC, HPLC, LC-MS/MS, GC-MS etc. with the development of integrated methods for evaluation of botanicals used in traditional medicine Assessment of herbal drugs through bio-analytical techniques, bioassay guided isolation, enzyme inhibition, pharmacological, microbiological, antiviral assays and safety related quality issues References global organizations, such as the WHO, USFDA, CDSCO, AYUSH, TCM and others to serve as a comprehensive document for enforcement agencies, NGOs and regulatory authorities
Author: Andrew G. Mtewa Publisher: John Wiley & Sons ISBN: 1119650232 Category : Science Languages : en Pages : 444
Book Description
Focusing on phytochemicals and their potential for drug discovery, this book offers a comprehensive resource on poisonous plants and their applications in chemistry and in pharmacology. Provides a comprehensive resource on phytotoxins, covering historical perspectives, modern applications, and their potential in drug discovery Covers the mechanisms, benefits, risks and management protocols of phytotoxins in a scientific laboratory and the usefulness in drug discovery Presents chapters in a carefully designed, clear order, making it an ideal resource for the academic researcher or the industry professional at any stage in their career
Author: World Health Organization Publisher: World Health Organization ISBN: 9241545100 Category : Medical Languages : en Pages : 122
Book Description
A collection of test procedures for assessing the identity, purity, and content of medicinal plant materials, including determination of pesticide residues, arsenic and heavy metals. Intended to assist national laboratories engaged in drug quality control, the manual responds to the growing use of medicinal plants, the special quality problems they pose, and the corresponding need for international guidance on reliable methods for quality control. Recommended procedures - whether involving visual inspection or the use of thin-layer chromatography for the qualitative determination of impurities - should also prove useful to the pharmaceutical industry and pharmacists working with these materials.
Author: Ravindra Kumar Pandey Publisher: CRC Press ISBN: 0429682832 Category : Health & Fitness Languages : en Pages : 202
Book Description
Due to the increase in the consumption of herbal medicine, there is a need to know which scientifically based methods are appropriate for assessing the quality of herbal medicines. Fingerprinting has emerged as a suitable technique for quality estimation. Chemical markers are used for evaluation of herbal medicines. Identification and quantification of these chemical markers are crucial for quality control of herbal medicines. This book provides updated knowledge on methodology, quality assessment, toxicity analysis and medicinal values of natural compounds.
Author: Yukihiro Shoyama Publisher: BoD – Books on Demand ISBN: 9533076828 Category : Medical Languages : en Pages : 296
Book Description
The authors of this thematic issue provide a comprehensive summary of most recent knowledge and references on quality control in wide fields. Quality control is essential for natural products like natural medicine and related food products. In this issue fifteen chapters have been included, discussing in detail various aspects of quality control. It will certainly prove useful not only for phytochemical researchers, but also many scientists working in numerous fields. Much effort has been invested by the contributors to share current information. Without their efforts and input 'Quality Control of Herbal Medicine and Related Areas' could not exist.
Author: Dilip Ghosh Publisher: CRC Press ISBN: 1351741349 Category : Medical Languages : en Pages : 615
Book Description
Globally, natural medicine has been considered as an important alternative to modern allopathic medicine. Although natural medicines are popular in society, only limited medicinal herbs have been scientifically evaluated for their potential in medical treatment. This book connects various aspects of the complex journey from traditional medicine to modern medicine. It provides information on topics including global regulations and regulatory hurdles, diverse nutritional challenges and potential health benefits, novel food innovations especially seed-to-clinic approaches, and future trends. FEATURES • Provides information on sustainable use of natural products in the development of new drugs and clinically validated herbal remedies • Discusses issues on evaluation and clinical aspects of herbal medicine, promotion and development, safety evaluation, metabolite profiling, biomarker analysis, formulation, and stability testing • Describes traditional uses of natural medicine through identification, isolation and structural characterization of their active components • Elucidates mechanisms of biological action, adverse effects and identification of their molecular targets of natural medicine • Multidisciplinary appeal including chemistry, pharmacology, pharmacognosy and cell and molecular biology, as well as integration with clinical medicine This book serves as an essential guide for individuals researching natural medicines, and industry employees in areas including drug development, pharmacology, natural products chemistry, clinical efficacy, ethnopharmacology, pharmacognosy, phytotherapy, phyto-technology and herbal science.
Author: Vivek Kothari Publisher: Gene-Tech Books ISBN: 9788189729141 Category : Natural products Languages : en Pages : 0
Book Description
The Introduction Of Biotechnology In Every Aspect Of Natural Products Research, Has Dramatically Facilitated The Potential Applications By The Industry Today. Natural Dyes, Alternative Food Ingredients And Preservation Materials And Microbial Polysaccharides, Are Only Some Examples Of The Growing Use Of Natural Products In The Industry. Importantly, The Pharmaceutical Sector Is Actively Involved In Natural Products Research, Since A Large Number Of Novel Compounds Have Medicinal Value. Although Natural Products Has The Chemical Diversity And Has Been Proven To Be Useful Templates, Their Sustainable Supply From The Original Biological Source Always Remain A Problem. Biotechnology Is Expected To Play A Major Role In The Production Of Natural Products Through Biosynthesis And Bioengineering Which Will Further Reduce The Dependence On A Large Amount Of Plant Samples And Hence Reduce The Pressure Of Reducing The Number Of Biogenetic Resources In The Tropical Forests. This Book Describes The Importance Of Biotechnology In The Search For Natural Products From Plants And Other Sources. It Aims To Provide Readers With A Comprehensive Information Which Will Help Them To Successfully Address Current Research And Application Issues In Natural Products And Biotechnology. Contents Chapter 1: Introduction To Natural Products; Chapter 2: Natural Products And Drug Discovery; Chapter 3: Genetic Manipulation And Natural Products; Chapter 4: Bioprocessing And Natural Products; Chapter 5: Enzyme Technology In Food Processing; Chapter 6: Biotechnology And Marine Natural Products; Chapter 7: Safety Evaluation Of Biotechnology Products Derived From Animals; Chapter 8: Medicinal Natural Products And Risk Assessment; Chapter 9: Safety Testing Of Medicinal Products Derived From Biotechnology; Chapter 10: Safety Evaluation Of Natural Food Products.
Author: Pulok K. Mukherjee Publisher: Elsevier ISBN: 0323984568 Category : Business & Economics Languages : en Pages : 858
Book Description
Evidence-Based Validation of Herbal Medicines: Translational Research on Botanicals brings together current thinking and practice in the characterization and validation of natural products. The book describes different approaches and techniques for evaluating the quality, safety and efficacy of herbal medicine, particularly methods to assess their activity and understand compounds responsible and their probable underlying mechanisms of action. This book brings together the views, expertise and experiences of scientific experts in the field of medicinal plant research, hence it will be useful for researcher who want to know more about the natural lead with their validation and also useful to exploit traditional medicines. Includes state-of-the-art methods for detecting, isolating and performing structure elucidation by degradation and spectroscopic techniques Highlights the trends in validation and value addition of herbal medicine with different scientific approaches used in therapeutics Contains several all-new chapters on topics such as traditional-medicine-inspired drug development to treat emerging viral diseases, medicinal plants in antimicrobial resistance, TLC bio profiling, botanicals as medicinal foods, bioprospecting and bioassay-guided isolation of medicinal plants, immunomodulators from medicinal plants, and more
Author: Shuang-Qing Zhang
Author: Shuang-Qing Zhang
Author: Pulok K. Mukherjee
Author: Andrew G. Mtewa
Author: World Health Organization
Author: Pulok K. Mukherjee
Author: Ravindra Kumar Pandey
Author: Yukihiro Shoyama
Author: Dilip Ghosh
Author: Vivek Kothari
Author: Pulok K. Mukherjee