Author: Publisher:
ISBN:
Category : Canada
Languages : en
Pages : 1832
Book Description
Canadiana
Author: Naturally Occurring Pyrrolizidine Alkaloids
Author: Dr. Abdel-Fatta RizkPublisher: CRC Press
ISBN: 9780849346507
Category : Science
Languages : en
Pages : 244
Book Description
Plants containing pyrrolizidine alkaloids are so numerous and widespread that they can be expected to be present in most environments. About 200 pyrrolizidine alkaloids have been isolated and identified from different plants. Interest in these alkaloids has increased in recent years due to their causative effects in the heavy loss of livestock in many countries. Naturally Occurring Pyrrolizidine Alkaloids discusses the plant sources and properties of pyrrolizidine alkaloids; extraction, fractionation and identification; various methods of spectrometry of pyrrolizidine alkaloids; quantitative determination; and the toxicity, carcinogenicity, pharmacology, and other biological activities of pyrrolizidine alkaloids. Researchers in veterinary and human medicine will find this book to be a fascinating and useful reference tool.
Biosynthesis of the Unique Necic Acid Moiety in Lycopsamine Type Pyrrolizidine Alkaloids
Author: Dorothee LangelPublisher: Cuvillier Verlag
ISBN: 3867276463
Category :
Languages : en
Pages : 227
Book Description
Chemistry and Toxicology of Pyrrolizidine Alkaloids
Author: A. R. MattocksPublisher:
ISBN:
Category : Medical
Languages : en
Pages : 424
Book Description
Pyrrolizidine Alkaloids
Author: Helmut WiedenfeldPublisher: Vandenhoeck & Ruprecht
ISBN: 3899714261
Category : Pyrrolizidines
Languages : en
Pages : 145
Book Description
Pyrrolizidine alkaloids show only minor toxicity in their native state, but are metabolized in the human or animal organisms to carcinogenic, teratogenic and mutagenic compounds, with the precise structure of these compounds being responsible for the metabolic toxification process. Therefore, to be able to evaluate the toxic potential of each alkaloid, it is essential to exactly know the structure of the respective compound. X-ray structure analysis is the appropriate method both for elucidating the structure and for determining other parameters, such as the lengths of the bonds that influence the metabolic process. This book describes the incidence and the process of the intoxication as well as the possibilities to how the substances may reach the organism. In addition, the compounds elucidated by X-ray structure analysis to date are shown in their three-dimensional structure and structure-toxicity relationships are discussed.Pyrrolizidinalkaloide weisen in nativem Zustand nur geringe Toxizität auf, werden jedoch zu kanzerogenen, teratogenen und mutagenen Verbindungen metabolisiert, wenn sie in den menschlichen oder tierischen Organismus gelangen. Der Verlauf dieser Toxifizierung hängt von der konkreten Struktur dieser Stoffe und weiteren Parametern ab. Zur Bestimmung dieser Faktoren stellt die Röntgenstrukturanalyse die geeignete Methode dar. Im vorliegenden Buch werden das Vorkommen, der Ablauf der Toxifizierung und die Möglichkeiten, wie die Stoffe in den Organismus gelangen können, beschrieben. Es werden die bislang durch Röntgenstrukturanalyse vermessenen Verbindungen in ihrer 3D-Struktur aufgefÃ"hrt und Struktur-Toxizitätsbeziehungen diskutiert.
Production, Distribution and Function of Secondary Metabolites
Author: Nicole Marie van DamPublisher:
ISBN: 9789090078557
Category : Alkaloids
Languages : en
Pages : 152
Book Description
Studies Directed Toward the Synthesis of Pyrrolizidine Alkaloids
Author: John Nicholas BonfiglioPublisher:
ISBN:
Category : Alkaloids
Languages : en
Pages : 366
Book Description
Alkaloid Synthesis
Author: Hans-Joachim KnölkerPublisher: Springer Science & Business Media
ISBN: 3642255299
Category : Science
Languages : en
Pages : 268
Book Description
Lycopodium Alkaloids: Isolation and Asymmetric Synthesis, by Mariko Kitajima and Hiromitsu Takayama.- Synthesis of Morphine Alkaloids and Derivatives, by Uwe Rinner and Tomas Hudlicky.- Indole Prenylation in Alkaloid Synthesis, by Thomas Lindel, Nils Marsch and Santosh Kumar Adla.- Marine Pyrroloiminoquinone Alkaloids, by Yasuyuki Kita and Hiromichi Fujioka.- Synthetic Studies on Amaryllidaceae and Other Terrestrially Derived Alkaloids, by Martin G. Banwell, Nadia Yuqian Gao, Brett D. Schwartz and Lorenzo V. White.- Synthesis of Pyrrole and Carbazole Alkaloids, by Ingmar Bauer and Hans-Joachim Knölker.-