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Author: Ernst Franzek Publisher: Springer Science & Business Media ISBN: 3709163536 Category : Medical Languages : en Pages : 156
Book Description
Contradictory results in schizophrenia research are generally explained as being due to genetic heterogeneity and multiple factor heredity in relationship to manifold environmental factors. The book reports a short overview of all relevant twin studies on schizophrenic psychoses and provides data and case histories on a systematic twin study based on a polydiagnostic approach carried out by two independently working psychiatrists. In addition to the internationally applied operational diagnostic systems of DSM-III-R and ICD 10 Leonhard’s subclassification of schizophrenic psychoses was used. Up to now this sophisticated methodological approach is unique in the world. The data provide strong evidence that the spectrum of psychoses with schizophrenic and schizophrenia-like symptoms is not a continuum of diseases. At least in Leonhard’s three major groups of cycloid psychoses, unsystematic schizophrenias and systematic schizophrenias genetic, somatic and psycho-social factors play a completely different etiological role. Cycloid psychoses and systematic schizophrenias are predominantly caused by "environmental” factors. In unsystematic schizophrenias, however, genetic predisposition is the main etiological factor and environmental factors are subordinate.
Author: Ernst Franzek Publisher: Springer Science & Business Media ISBN: 3709163536 Category : Medical Languages : en Pages : 156
Book Description
Contradictory results in schizophrenia research are generally explained as being due to genetic heterogeneity and multiple factor heredity in relationship to manifold environmental factors. The book reports a short overview of all relevant twin studies on schizophrenic psychoses and provides data and case histories on a systematic twin study based on a polydiagnostic approach carried out by two independently working psychiatrists. In addition to the internationally applied operational diagnostic systems of DSM-III-R and ICD 10 Leonhard’s subclassification of schizophrenic psychoses was used. Up to now this sophisticated methodological approach is unique in the world. The data provide strong evidence that the spectrum of psychoses with schizophrenic and schizophrenia-like symptoms is not a continuum of diseases. At least in Leonhard’s three major groups of cycloid psychoses, unsystematic schizophrenias and systematic schizophrenias genetic, somatic and psycho-social factors play a completely different etiological role. Cycloid psychoses and systematic schizophrenias are predominantly caused by "environmental” factors. In unsystematic schizophrenias, however, genetic predisposition is the main etiological factor and environmental factors are subordinate.
Author: Pamela Spiro Wagner Publisher: Macmillan ISBN: 9780312320652 Category : Biography & Autobiography Languages : en Pages : 346
Book Description
Relates the stories of a pair of identical twin sisters, a schizophrenic and a psychiatrist, in an account that traces the deterioration of the favored sister into mental illness, and the other's emergence from her troubled sibling's shadow.
Author: Gareth W. Roberts Publisher: Cambridge University Press ISBN: 9780521425582 Category : Medical Languages : en Pages : 204
Book Description
This volume provides an introduction to the essential techniques required for studying the molecular biology of brain disease. The approaches and strategies for investigations of gene structure and regulation are described with reference to the molecular genetics of prion and Alzheimer's disease. The effects of aberrant gene regulation can also be examined at the protein level by immunocytochemistry and autoradiography. Improved understanding of basic biology has resulted in new approaches to animal models using transgenic techniques and new therapeutic approaches. The volume is structured to illustrate all these approaches and demonstrate the practice and promise of molecular neuropathology.
Author: Michael Poyurovsky Publisher: Cambridge University Press ISBN: 1107000122 Category : Medical Languages : en Pages : 249
Book Description
This is the first book to address the clinical and neurobiological interface between schizophrenia and obsessive-compulsive disorder (OCD). There is growing evidence that obsessive-compulsive symptoms in schizophrenia are prevalent, persistent and characterized by a distinct pattern of familial inheritance, neurocognitive deficits and brain activation. This text provides guidelines for differential diagnosis of schizophrenic patients with obsessive-compulsive symptoms, and patients with primary OCD alongside poor insight, psychotic features or schizotypal personality. Written by a leading expert in the coexistence of obsessive-compulsive and schizophrenic phenomena, Schizo-Obsessive Disorder uses numerous case studies to present diagnostic guidelines and to describe a recommended treatment algorithm, demystifying this complex disorder and aiding its effective management. The book is essential reading for psychiatrists, neurologists and the wider range of multidisciplinary mental health practitioners.
Author: Sir Michael Rutter Publisher: Wiley-Blackwell ISBN: 9781405110624 Category : Psychology Languages : en Pages : 272
Book Description
In this major new book, eminent scientist Professor Sir Michael Rutter gets behind the hype of the behavioral genetics debate to provide a balanced and authoritative overview of the genetic revolution and its implications for understanding human behavior. Written by one of the world's leading figures in child psychology and psychiatry, Professor Sir Michael Rutter Provides non-technical explanation of genetics to diffuse the sensational debates surrounding the topic Sets out in layman's terms what genes do, how much is nature and how much is nurture Argues that nature and nurture are not truly separate and gives examples of how the two interact Looks at the implications of genetic findings for policy and practice The book will inform public debate about the implications of the Human Genome Project and, more broadly, the field of genetic science
Author: Philip D. Harvey Publisher: Cambridge University Press ISBN: 1107013208 Category : Medical Languages : en Pages : 341
Book Description
Provides state-of-the-art information about cognition in schizophrenia with a wide ranging focus on measuring and treating cognitive deficits.
Author: Robin M. Murray Publisher: Cambridge University Press ISBN: 9780521121026 Category : Medical Languages : en Pages : 0
Book Description
An international team of leading researchers and clinicians provides the first comprehensive, epidemiological overview of this multi-faceted and still-perplexing disorder. Controversial issues such as the validity of discrete or dimensional classifications of schizophrenia and the continuum between psychosis and 'normality' are explored in depth. Separate chapters are devoted to topics of particular relevance to schizophrenia such as suicide, violence and substance abuse. Finally, new prospects for treatment and prevention are considered.
Author: Ernst Franzek
Author: Ernst Franzek
Author: Irving I. Gottesman
Author: Christian Astrup
Author: Pamela Spiro Wagner
Author: Karl Leonhard
Author: Gareth W. Roberts
Author: Michael Poyurovsky
Author: Sir Michael Rutter
Author: Philip D. Harvey
Author: Robin M. Murray