Protooncogenes and Growth Factors in Steroid Hormone Induced Growth and Differentiation PDF Download

Author: Sohaib A. Khan
Publisher: CRC Press
ISBN: 9780849386725
Category : Medical
Languages : en
Pages : 296

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Book Description
Protooncogenes and Growth Factors in Steroid Hormone Induced Growth and Differentiation reviews current information regarding the complex nature of hormone-induced cell growth and differentiation. The contributors examine the emerging consensus that protooncogenes and growth factors mediate perhaps the most crucial steps leading to cell growth and differentiation. The primary objective of this book is to unite the status of current research related to protooncogenes and growth factors from diverse physiological systems to help readers gain a comprehensive understanding of the subject. Leading researchers have contributed outstanding chapters pertaining to steroid hormone-regulated cell growth and differentiation in normal and/or neoplastic tissues. This book will appeal to basic science researchers, clinicians, industrial researchers, and graduate students.

Author: David O. Norris
Publisher: Academic Press
ISBN: 0080958095
Category : Technology & Engineering
Languages : en
Pages : 1681

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Book Description
This series of volumes represents a comprehensive and integrated treatment of reproduction in vertebrates from fishes of all sorts through mammals. It is designed to provide a readable, coordinated description of reproductive basics in each group of vertebrates as well as an introduction to the latest trends in reproductive research and our understanding of reproductive events. Whereas each chapter and each volume is intended to stand alone as a review of that topic or vertebrate group, respectively, the volumes are prepared so as to provide a thorough topical treatment across the vertebrates. Terminology has been standardized across the volumes to reduce confusion where multiple names exist in the literature, and a comprehensive glossary of these terms and their alternative names is provided. A complete, essential and up to date reference for research scientists working on vertebrate hormones and reproduction - and on animlals as models in human reproductive research Covers the endocrinology, neuroendocrinology, physiology, behaviour and anatomy of vertebrate reproduction Structured coverage of the major themes for all five vertebrate groups allows a consistent treatment for all Special chapters elaborate on features specific to individual vertebrate groups and to comparative aspects, similarities and differences between them

Author: Stanley R. Glasser
Publisher: CRC Press
ISBN: 0203219031
Category : Medical
Languages : en
Pages : 1079

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Book Description
The Endometrium is devoted to a comprehensive multi-disciplinary account of the uterine endometrium. This book is the first to define the regulatory biological interrelationships between epithelial and stromal cell phenotypes, endothelial cells, extracellular matrix and immunobiological elements. It highlights their relevance to clinical conditions

Author: David Norris
Publisher: Academic Press
ISBN: 0080958079
Category : Technology & Engineering
Languages : en
Pages : 433

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Book Description
This series of volumes represents a comprehensive and integrated treatment of reproduction in vertebrates from fishes of all sorts through mammals. It is designed to provide a readable, coordinated description of reproductive basics in each group of vertebrates as well as an introduction to the latest trends in reproductive research and our understanding of reproductive events. Whereas each chapter and each volume is intended to stand alone as a review of that topic or vertebrate group, respectively, the volumes are prepared so as to provide a thorough topical treatment across the vertebrates. Terminology has been standardized across the volumes to reduce confusion where multiple names exist in the literature, and a comprehensive glossary of these terms and their alternative names is provided. A complete, essential and up to date reference for research scientists working on vertebrate hormones and reproduction - and on animlals as models in human reproductive research Covers the endocrinology, neuroendocrinology, physiology, behaviour and anatomy of vertebrate reproduction Structured coverage of the major themes for all five vertebrate groups allows a consistent treatment for all Special chapters elaborate on features specific to individual vertebrate groups and to comparative aspects, similarities and differences between them

Author: Fuller W. Bazer
Publisher: Springer Science & Business Media
ISBN: 1461218047
Category : Medical
Languages : en
Pages : 579

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Book Description
A comprehensive, cutting-edge review of the complex interactions between maternal and fetal-placental tissues that control the establishment and maintenance of pregnancy, the proper development of the fetus, the birth process, and the behavioral aspects of bonding between mother and newborn. Expert researchers review the endocrine and physiological events that culminate in the delivery of offspring, and provide a solid base of comparative information on the menstrual cycle of primates, including humans. They also discuss the sources and functions of both steroid and protein hormones from the placenta and the details of their effects on uterine function, placental development, fetal growth and well-being, and maternal responses to pregnancy. This book will become the standard reference source not only for reproductive scientists, but also for those clinicians who want better to understand the complex factors that affect pregnancy-and their pregnant patients.

Author: Robert B. Dickson
Publisher: Springer Science & Business Media
ISBN: 1461312590
Category : Medical
Languages : en
Pages : 432

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Book Description
Mammary Tumor Cell Cycle, Differentiation and Metastasis is the fifth volume since 1988 in a series designed to broadly examine current advances in the cellular and molecular biology of breast cancer. As in previous volumes, the editors have invited recognized experts in cutting-edge topics to provide a chapter focused on their area of research. The editors have turned to the researchers who study rodent models of the disease and to those who study the cellular and molecular basis of human breast cancer. The first section of the book is devoted to new mouse models of mammary development and tumorigenesis. The second section moves to studies of human breast cancer and focuses on receptors, signalling, and the cell cycle. The final section deals with defective tissue interactions in human breast cancer. We are now in a period of extremely rapid accumulation of data on the molecular and cellular biology of breast cancer. These findings are highlighted in chapters from Mammary Tumor Cell Cycle, Differentiation and Metastasis: Advances in Cellular and Molecular Biology of Breast Cancer.

Author: Lutz Birnbaumer
Publisher: Elsevier
ISBN: 0080534147
Category : Medical
Languages : en
Pages : 381

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Book Description
Hormones and Signaling focuses on the mechanism of gene regulation at the cellular level. It also covers the way hormones act to modulate gene regulation and animal development.Includes information on: - Nuclear receptors, coactivators, and corepressors - Membrane receptors, kinases, and phosphorylation on cascades - Hormonal regulation of development - Calcium channels and neurotransmitters - Chromatin, transcription factors, and regulation of gene expression - JAK/STAT pathways - Hormone-regulated development and gene "knock-out"

Author: John P. Bilezikian
Publisher: Academic Press
ISBN: 0080568750
Category : Medical
Languages : en
Pages : 2074

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Book Description
Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. - Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants...it is all in one source written by the experts in the field - The essential resource for anyone involved in the study of bones and bone diseases - Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics - Readers can easily search and locate information quickly as it will be online with this new edition

Author: C. Marcelo Aldaz
Publisher: John Wiley & Sons
ISBN: 9780471169017
Category : Health & Fitness
Languages : en
Pages : 320

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Book Description
Progress in Clinical and Biological Research, Volume 396 Etiology of Breast and Gynecological Cancers Proceedings of the Ninth International Conference on Carcinogenesis and Risk Assessment, Held in Austin, Texas, November 29–December 2, 1995 C. Marcelo Aldaz, Michael N. Gould, John McLachlan, and Thomas J. Slaga, Editors Accounting for 150 cancers per 100,000 people at risk, breast cancer and gynecological cancer together constitute a major public health concern. These cancers have a common target population, and many also have common etiological features, including hormonal factors, genetic changes in genes such as BRCA1, and environmental factors such as ionizing radiation, viruses, chemical xenobiotics, diet, and nutrition. Etiology of Breast and Gynecological Cancers explores important environmental and genetic factors that are key to the induction of these cancers. The book takes a broad perspective, with chapters contributed by laboratory investigators and clinicians, as well as by epidemiologists. It emphasizes validation and issues of extrapolation from animal models to humans and their impact on risk assessment, and it also discusses intervention strategies in terms of chemoprevention, which has the potential to reduce the morbidity and mortality from these cancers in women. Etiology of Breast and Gynecological Cancers explores a wide variety of topics, including: recent advances in the molecular genetics of hereditary breast and ovarian cancer molecular perspectives on cancer, the cell cycle, and the inherited disorder ataxia-telangiectasia genotoxicity of environmental agents in human mammary epithelial cells rodent model of reproductive tract leiomyomata estrogens and the genetic control of tumor growth Featuring 19 outstanding presentations from leading researchers in an array of disciplines, Etiology of Breast and Gynecological Cancers is an important resource for investigators and clinicians in oncology, epidemiology, and public health, providing new understanding of the sources of these disorders as well as new directions for treatment and prevention.

Author: Edward J. Pavlik
Publisher: Birkhäuser
ISBN: 1461220041
Category : Science
Languages : en
Pages : 248

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Book Description
These two volumes on Estrogens, Progestins, and Their Antagonists repre sent a thematic extension of the series, Hormones in Health and Disease. The first publication in the series, Steroid Hormone Receptors: Basic and Clinical Aspects, focused on recent advances in the anatomy of steroid receptors and members of the steroid receptor superfamily. Consistent with the spirit of the series, the authors addressed issues of clinical significance of steroid receptor detection in hormone-related disorders. The second volume in the series, Hormones and Cancer, attempted a more direct examination of ac tions of hormones in cancerous tissues and cells. In these two volumes, which together form the third in the series, the editor, Dr. Edward Pavlik, has introduced a team of leading investigators engaged in research on various aspects of the steroids that regulate female reproductive physiology. Estrogens and progestins, the main components of the most widely used contraceptive pills, have found a variety of uses in clinical endocrinology. These volumes contain discussions that range from the introduction of novel hormonal ligands to "hormonal antagonism by steroid analogs. A balanced treatment is provided of applications of the steroids in treatment and management of hormone-dependent conditions and malignancies. The remarkable synthesis of literature contained in this volume will provide a reader with both the fundamental concepts underly ing steroid hormone physiology and the clinical applications of observations made on basic aspects of hormone action. I congratulate the editorial leadership of Dr.