Protein Stabilization by the Rational Design of Surface Charge-charge Interactions

Protein Stabilization by the Rational Design of Surface Charge-charge Interactions PDF Author: Katrina L Schweiker
Publisher:
ISBN:
Category : Stability
Languages : en
Pages :

Book Description


Computer Methods Part A

Computer Methods Part A PDF Author:
Publisher: Academic Press
ISBN: 0080923291
Category : Science
Languages : en
Pages : 491

Book Description
The combination of faster, more advanced computers and more quantitatively oriented biomedical researchers has recently yielded new and more precise methods for the analysis of biomedical data. These better analyses have enhanced the conclusions that can be drawn from biomedical data, and they have changed the way that experiments are designed and performed. This volume, along with previous and forthcoming 'Computer Methods' volumes for the Methods in Enzymology serial, aims to inform biomedical researchers about recent applications of modern data analysis and simulation methods as applied to biomedical research.

Thermostable Proteins

Thermostable Proteins PDF Author: Srikanta Sen
Publisher: CRC Press
ISBN: 143983914X
Category : Science
Languages : en
Pages : 184

Book Description
This book covers the basic structural, thermodynamic and kinetic principles are covered and molecular strategies for the adaptation to high temperatures revealed by structure analysis are delineated. The roles of fluctuations, hydration and internal packing are thoroughly dicussed. Enzymes with a particular industrial importance, the subtilisin-like serine proteases, have been extensively studied by protein engineering. One extensive chapter is devoted to the present state of knowledge concerning structure-function relations and the origin of the their structural stability. Last but not least, computational and experimental approaches for the design of proteins with increased thermal stability based on sequences or 3D structures are present

Electrostatics

Electrostatics PDF Author: Hüseyin Canbolat
Publisher: BoD – Books on Demand
ISBN: 9535102397
Category : Technology & Engineering
Languages : en
Pages : 164

Book Description
In this book, the authors provide state-of-the-art research studies on electrostatic principles or include the electrostatic phenomena as an important factor. The chapters cover diverse subjects, such as biotechnology, bioengineering, actuation of MEMS, measurement and nanoelectronics. Hopefully, the interested readers will benefit from the book in their studies. It is probable that the presented studies will lead the researchers to develop new ideas to conduct their research.

Enzyme Catalysis in Organic Synthesis, 3 Volume Set

Enzyme Catalysis in Organic Synthesis, 3 Volume Set PDF Author: Karlheinz Drauz
Publisher: John Wiley & Sons
ISBN: 3527325476
Category : Science
Languages : en
Pages : 2143

Book Description
This comprehensive three-volume set is the standard reference in the field of organic synthesis, catalysis and biocatalysis. Edited by a highly experienced and highly knowledgeable team with a tremendous amount of experience in this field and its applications, this edition retains the successful concept of past editions, while the contents are very much focused on new developments in the field. All the techniques described are directly transferable from the lab to the industrial scale, making for a very application-oriented approach. A must for all chemists and biotechnologists.

Methods in Protein Structure and Stability Analysis: Conformational stability, size, shape, and surface of protein molecules

Methods in Protein Structure and Stability Analysis: Conformational stability, size, shape, and surface of protein molecules PDF Author: Vladimir N. Uversky
Publisher: Nova Publishers
ISBN: 9781600217043
Category : Science
Languages : en
Pages : 414

Book Description
Protein research is a frontier field in science. Proteins are widely distributed in plants and animals and are the principal constituents of the protoplasm of all cells, and consist essentially of combinations of a-amino acids in peptide linkages. Twenty different amino acids are commonly found in proteins, and serve as enzymes, structural elements, hormones, immunoglobulins, etc., and are involved throughout the body, and in photosynthesis. This book gathers new leading-edge research from throughout the world in this exciting and exploding field of research.

Understanding Enzymes

Understanding Enzymes PDF Author: Allan Svendsen
Publisher: CRC Press
ISBN: 9814669334
Category : Mathematics
Languages : en
Pages : 884

Book Description
Understanding Enzymes: Function, Design, Engineering, and Analysis focuses on the understanding of enzyme function and optimization gained in the past decade, past enzyme function analysis, enzyme engineering, and growing insights from the simulation work and nanotechnology measurement of enzymes in action in vitro or in silico. The book also prese

Rational Design of Stable Protein Formulations

Rational Design of Stable Protein Formulations PDF Author: John F. Carpenter
Publisher: Springer Science & Business Media
ISBN: 1461505577
Category : Medical
Languages : en
Pages : 218

Book Description
Recombinant proteins and polypeptides continue to be the most important class of biotechnology-derived agents in today's pharmaceutical industry. Over the past few years, our fundamental understanding of how proteins degrade and how stabilizing agents work has made it possible to approach formulation of protein pharmaceuticals from a much more rational point of view. This book describes the current level of understanding of protein instability and the strategies for stabilizing proteins under a variety of stressful conditions.

Biocatalysis for Practitioners

Biocatalysis for Practitioners PDF Author: Gonzalo de Gonzalo
Publisher: John Wiley & Sons
ISBN: 3527824448
Category : Science
Languages : en
Pages : 528

Book Description
This reference book originates from the interdisciplinary research cooperation between academia and industry. In three distinct parts, latest results from basic research on stable enzymes are explained and brought into context with possible industrial applications. Downstream processing technology as well as biocatalytic and biotechnological production processes from global players display the enormous potential of biocatalysts. Application of "extreme" reaction conditions (i.e. unconventional, such as high temperature, pressure, and pH value) - biocatalysts are normally used within a well defined process window - leads to novel synthetic effects. Both novel enzyme systems and the synthetic routes in which they can be applied are made accessible to the reader. In addition, the complementary innovative process technology under unconventional conditions is highlighted by latest examples from biotech industry.

Protein Engineering and Design

Protein Engineering and Design PDF Author: Sheldon J. Park
Publisher: CRC Press
ISBN: 1420076590
Category : Medical
Languages : en
Pages : 434

Book Description
Experimental protein engineering and computational protein design are broad but complementary strategies for developing proteins with altered or novel structural properties and biological functions. By describing cutting-edge advances in both of these fields, Protein Engineering and Design aims to cultivate a synergistic approach to protein science