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Prostate Cancer and Pesticide Exposure in Diverse Populations in California's Central Valley

Prostate Cancer and Pesticide Exposure in Diverse Populations in California's Central Valley PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 26

Book Description
This project is a pilot case-control study of pesticide exposure and prostate cancer, that (1) poor measurement of pesticide exposure in studies of prostate cancer risk factors explains null findings to date; (2) a proposed method of recruiting and approaching cases and controls to a large population-based case-control study will result in acceptable response rates, but also will be biased; (3) We will be able to obtain sufficient DNA from mailed buccal swab kits to assess effect modification by known relevant genes, and have sufficient stored DNA to assess the impact of genes that may be discovered in future. We found that there are substantial increased risks of prostate cancer with long term exposure to a number of pesticides, despite the limitations of our pilot study (namely, small sample size). We addressed selection bias, and after doing so, still noted increased risks for prostate cancer with certain pesticides. Our study design appears to ensure that a large scale study would both be successful, and is warranted.

Prostate Cancer and Pesticide Exposure in Diverse Populations in California's Central Valley

Prostate Cancer and Pesticide Exposure in Diverse Populations in California's Central Valley PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 26

Book Description
This project is a pilot case-control study of pesticide exposure and prostate cancer, that (1) poor measurement of pesticide exposure in studies of prostate cancer risk factors explains null findings to date; (2) a proposed method of recruiting and approaching cases and controls to a large population-based case-control study will result in acceptable response rates, but also will be biased; (3) We will be able to obtain sufficient DNA from mailed buccal swab kits to assess effect modification by known relevant genes, and have sufficient stored DNA to assess the impact of genes that may be discovered in future. We found that there are substantial increased risks of prostate cancer with long term exposure to a number of pesticides, despite the limitations of our pilot study (namely, small sample size). We addressed selection bias, and after doing so, still noted increased risks for prostate cancer with certain pesticides. Our study design appears to ensure that a large scale study would both be successful, and is warranted.

Advancing the Science of Cancer in Latinos

Advancing the Science of Cancer in Latinos PDF Author: Amelie G. Ramirez
Publisher: Springer Nature
ISBN: 303029286X
Category : Medical
Languages : en
Pages : 320

Book Description
This open access book gives an overview of the sessions, panel discussions, and outcomes of the Advancing the Science of Cancer in Latinos conference, held in February 2018 in San Antonio, Texas, USA, and hosted by the Mays Cancer Center and the Institute for Health Promotion Research at UT Health San Antonio. Latinos – the largest, youngest, and fastest-growing minority group in the United States – are expected to face a 142% rise in cancer cases in coming years. Although there has been substantial advancement in cancer prevention, screening, diagnosis, and treatment over the past few decades, addressing Latino cancer health disparities has not nearly kept pace with progress. The diverse and dynamic group of speakers and panelists brought together at the Advancing the Science of Cancer in Latinos conference provided in-depth insights as well as progress and actionable goals for Latino-focused basic science research, clinical best practices, community interventions, and what can be done by way of prevention, screening, diagnosis, and treatment of cancer in Latinos. These insights have been translated into the chapters included in this compendium; the chapters summarize the presentations and include current knowledge in the specific topic areas, identified gaps, and top priority areas for future cancer research in Latinos. Topics included among the chapters: Colorectal cancer disparities in Latinos: Genes vs. Environment Breast cancer risk and mortality in women of Latin American origin Differential cancer risk in Latinos: The role of diet Overcoming barriers for Latinos on cancer clinical trials Es tiempo: Engaging Latinas in cervical cancer research Emerging policies in U.S. health care Advancing the Science of Cancer in Latinos proves to be an indispensable resource offering key insights into actionable targets for basic science research, suggestions for clinical best practices and community interventions, and novel strategies and advocacy opportunities to reduce health disparities in Latino communities. It will find an engaged audience among researchers, academics, physicians and other healthcare professionals, patient advocates, students, and others with an interest in the broad field of Latino cancer.

Prostate Cancer

Prostate Cancer PDF Author: Jack H. Mydlo
Publisher: Academic Press
ISBN: 0128005920
Category : Science
Languages : en
Pages : 674

Book Description
Prostate Cancer, Science and Clinical Practice, Second Edition, continues to be an important translational reference that bridges the gap between science and clinical medicine. It reviews the biological processes that can be implicated in the disease, reviews current treatments, highlights the pitfalls where relevant, and examines the scientific developments that might result in future treatments. Key chapters from the previous edition have been updated, and a plethora of new chapters describe new concepts of prostate cancer biology and newly developed therapeutics. Each chapter has been written by internationally recognized specialists on prostate cancer epidemiology, genetic susceptibility, cancer metastases, prostate physiology, proteomics, new therapeutics, and clinical trials. Presents a comprehensive, translational source for all aspects of prostate cancer in one reference work Provides a common language for cancer researchers, oncologists, and urologists to discuss prostate tumors and how prostate cancer metastases affects other major organ systems Offers insights to research clinicians, giving them a key understanding the molecular basis of prostate cancer Offers insights to cancer researchers into how clinical observations and practices can feed back into the research cycle and, therefore, can contribute to the development of more targeted genomic and proteomic assays

Research Utilizing the California Cancer Registry

Research Utilizing the California Cancer Registry PDF Author:
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 36

Book Description


Environmental Health Perspectives

Environmental Health Perspectives PDF Author:
Publisher:
ISBN:
Category : Environmental health
Languages : en
Pages : 1576

Book Description


Occupational Cancers

Occupational Cancers PDF Author: Sisko Anttila
Publisher: Springer
ISBN: 1447128257
Category : Medical
Languages : en
Pages : 612

Book Description
This book is a comprehensive guide to occupational factors of malignant diseases. It discusses potentially work-related malignancies, in the context of exposure assessment, specific clinical and pathological features of occupational cancer and biomarkers of exposure and disease. Epidemiological data about risk ratios of the cancer in question are reviewed for various occupations and with exposure to specific carcinogens, carcinogenic mechanisms, host susceptibility factors (genetic and other) and other environmental and life-style risk factors. Aspects such as surveillance of workers exposed to carcinogens and strategies for prevention of occupational cancer are also discussed. Occupational Cancers is aimed at oncologists, pathologists, residents in training, clinical researchers, clinicians in occupational health, epidemiologists, pulmonologists, lawyers and public health officials.

Veterans and Agent Orange

Veterans and Agent Orange PDF Author: Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides
Publisher: National Academies Press
ISBN: 9780309075299
Category : Medical
Languages : en
Pages : 791

Book Description
Have U.S. military personnel experienced health problems from being exposed to Agent Orange, its dioxin contaminants, and other herbicides used in Vietnam? This definitive volume summarizes the strength of the evidence associating exposure during Vietnam service with cancer and other health effects and presents conclusions from an expert panel. Veterans and Agent Orange provides a historical review of the issue, examines studies of populations, in addition to Vietnam veterans, environmentally and occupationally exposed to herbicides and dioxin, and discusses problems in study methodology. The core of the book presents What is known about the toxicology of the herbicides used in greatest quantities in Vietnam. What is known about assessing exposure to herbicides and dioxin. What can be determined from the wide range of epidemiological studies conducted by different authorities. What is known about the relationship between exposure to herbicides and dioxin, and cancer, reproductive effects, neurobehavioral disorders, and other health effects. The book describes research areas of continuing concern and offers recommendations for further research on the health effects of Agent Orange exposure among Vietnam veterans. This volume will be critically important to both policymakers and physicians in the federal government, Vietnam veterans and their families, veterans organizations, researchers, and health professionals.

Recognition and Management of Pesticide Poisonings (5th Ed. )

Recognition and Management of Pesticide Poisonings (5th Ed. ) PDF Author: J. Routt Reigart
Publisher: DIANE Publishing
ISBN: 1437914527
Category : Technology & Engineering
Languages : en
Pages : 238

Book Description
This 5th ed. is an update and expansion of the 1989 4th ed. This EPA manual provides health professionals with information on the health hazards of pesticides currently in use, and current consensus recommendations for management of poisonings and injuries caused by them. As with previous updates, this new ed. incorporates new pesticide products that are not necessarily widely known among health professionals. Contents: (1) General Information: Introduction; General Principles in the Management of Acute Pesticide Poisonings; Environmental and Occupational History; (2) Insecticides; (3) Herbicides; (4) Other Pesticides; (5) Index of Signs and Symptoms; Index of Pesticide Products. Charts and tables.

Pesticides in Crop Production

Pesticides in Crop Production PDF Author: Prabhat Kumar Srivastava
Publisher: John Wiley & Sons
ISBN: 1119432197
Category : Technology & Engineering
Languages : en
Pages : 312

Book Description
A guide to the diversity of pesticides used in modern agricultural practices, and the relevant social and environmental issues Pesticides in Crop Production offers an important resource that explores pesticide action in plants; pesticide metabolism in soil microbes, plants and animals; bioaccumulation of pesticides and sensitiveness of microbiome towards pesticides. The authors explore pesticide risk assessment, the development of pesticide resistance in pests, microbial remediation of pesticide intoxicated legumes and pesticide toxicity amelioration in plants by plant hormones. The authors include information on eco-friendly pest management. They review the impact of pesticides on soil microorganism, crops and other plants along with the impact on other organisms like aquatic fauna and terrestrial animals including human beings. The book also contains an analysis of pesticide by GC-MS/MS (Gas Chromatography tandem Mass Spectrometry) a reliable method for the quantification and confirmation of multiclass pesticide residues. This important book: Offers a comprehensive guide to the use of the diversity of pesticides and the pertinent social and environmental issues Explores the impact of pesticides from morphological, anatomical, physiological and biochemical perspectives Shows how pesticides affects soil microorganisms, crops and other plants along with the impact on other organisms like aquatic fauna and animals Critically examines whether chemical pesticides are boon or bane and whether they can be replaced by environmental friendly pesticides Written for students, researchers and professionals in agriculture, botany, entomology and biotechnology, Pesticides in Crop Production examines the effects of chemical pesticides and the feasibility of using bio-pesticides.

Toxicological Profile for Chlordane

Toxicological Profile for Chlordane PDF Author:
Publisher:
ISBN:
Category : Chlordan
Languages : en
Pages : 286

Book Description