Protein Folding and Misfolding

Protein Folding and Misfolding PDF Author: Heinz Fabian
Publisher: Springer Science & Business Media
ISBN: 3642222307
Category : Science
Languages : en
Pages : 257

Book Description
Infrared spectroscopy is a new and innovative technology to study protein folding/misfolding events in the broad arsenal of techniques conventionally used in this field. The progress in understanding protein folding and misfolding is primarily due to the development of biophysical methods which permit to probe conformational changes with high kinetic and structural resolution. The most commonly used approaches rely on rapid mixing methods to initiate the folding event via a sudden change in solvent conditions. Traditionally, techniques such as fluorescence, circular dichroism or visible absorption are applied to probe the process. In contrast to these techniques, infrared spectroscopy came into play only very recently, and the progress made in this field up to date which now permits to probe folding events over the time scale from picoseconds to minutes has not yet been discussed in a book. The aim of this book is to provide an overview of the developments as seen by some of the main contributors to the field. The chapters are not intended to give exhaustive reviews of the literature but, instead to illustrate examples demonstrating the sort of information, which infrared techniques can provide and how this information can be extracted from the experimental data. By discussing the strengths and limitations of the infrared approaches for the investigation of folding and misfolding mechanisms this book helps the reader to evaluate whether a particular system is appropriate for studies by infrared spectroscopy and which specific advantages the techniques offer to solve specific problems.

Biological and Biomedical Infrared Spectroscopy

Biological and Biomedical Infrared Spectroscopy PDF Author: Andreas Barth
Publisher: IOS Press
ISBN: 1607500450
Category : Science
Languages : en
Pages : 448

Book Description
Although infrared spectroscopy has been applied with success to the study of important biological and biomedical processes for many years, key advances in this vibrant technique have led to its increasing use, ranging from characterization of individual macromolecules (DNA, RNA, lipids, proteins) to human tissues, cells and their components. Infrared spectroscopy thus has a significant role to play in the analysis of the vast number of genes and proteins being identified by the various genomic sequencing projects. Whilst this book gives an overview of the field, it highlights more recent developments, such as the use of bright synchrotron radiation for recording infrared spectra, the development of two-dimensional infrared spectroscopy and the ability to record infrared spectra at ultra fast speeds.

Quantitative Infrared Spectroscopy for Understanding of a Condensed Matter

Quantitative Infrared Spectroscopy for Understanding of a Condensed Matter PDF Author: Takeshi Hasegawa
Publisher: Springer
ISBN: 4431564934
Category : Science
Languages : en
Pages : 207

Book Description
This book is intended to provide a course of infrared spectroscopy for quantitative analysis, covering both bulk matter and surface/interface analyses. Although the technology of Fourier transform infrared (FT-IR) spectroscopy was established many years ago, the full potential of infrared spectroscopy has not been properly recognized, and its intrinsic potential is still put aside. FT-IR has outstandingly useful characteristics, however, represented by the high sensitivity for monolayer analysis, highly reliable quantitativity, and reproducibility, which are quite suitable for surface and interface analysis. Because infrared spectroscopy provides rich chemical information—for example, hydrogen bonding, molecular conformation, orientation, aggregation, and crystallinity—FT-IR should be the first choice of chemical analysis in a laboratory. In this book, various analytical techniques and basic knowledge of infrared spectroscopy are described in a uniform manner. In particular, techniques for quantitative understanding are particularly focused for the reader’s convenience.

Infrared Spectroscopy

Infrared Spectroscopy PDF Author: Daniel Cozzolino
Publisher: Nova Science Publishers
ISBN: 9781629485218
Category : Infrared spectroscopy
Languages : en
Pages : 0

Book Description
Since Herschel discovered light in the near-infrared region as early as 1800, the NIR region of the electromagnetic spectrum, once regarded as having little potential for analytical work, has now become one of the most promising techniques for molecular spectroscopy in several analytical fields. Over the last three decades, the development of new applications of infrared spectroscopy has been associated with increased power of computers and progress in chemometrics. This book introduces and presents several novel applications of NIR spectroscopy in biology, medicine, food science, the pharmaceutical sciences, polymers and minerals, for the first time in a single book. It is written by an international panel of scientists with a vast expertise in the field of infrared spectroscopy, providing unique views and perspectives on both practical and theoretical applications. This book should serve as a reference source for undergraduate and postgraduate students, scientists and researchers in the field of infrared spectroscopy.

Progress in Adhesion and Adhesives, Volume 3

Progress in Adhesion and Adhesives, Volume 3 PDF Author: K. L. Mittal
Publisher: John Wiley & Sons
ISBN: 111952637X
Category : Technology & Engineering
Languages : en
Pages : 432

Book Description
A solid collection of interdisciplinary review articles on the latest developments in adhesion science and adhesives technology With the ever-increasing amount of research being published, it is a Herculean task to be fully conversant with the latest research developments in any field, and the arena of adhesion and adhesives is no exception. Thus, topical review articles provide an alternate and very efficient way to stay abreast of the state-of-the-art in many subjects representing the field of adhesion science and adhesives. Based on the success of the preceding volumes in this series "Progress in Adhesion and Adhesives"), the present volume comprises 12 review articles published in Volume 5 (2017) of Reviews of Adhesion and Adhesives. The subject of these 12 reviews fall into the following general areas: 1. Nanoparticles in reinforced polymeric composites. 2. Wettability behavior and its modification, including superhydrophobic surfaces. 3. Ways to promote adhesion, including rubber adhesion. 4. Adhesives and adhesive joints 5. Dental adhesion. The topics covered include: Nanoparticles as interphase modifiers in fiber reinforced polymeric composites; fabrication of micro/nano patterns on polymeric substrates to control wettability behavior; plasma processing of aluminum alloys to promote adhesion; UV-curing of adhesives; functionally graded adhesively bonded joints; adhesion between unvulgarized elastomers; electrowetting for digital microfluidics; control of biofilm at the tooth-restoration bonding interface; easy-to-clean superhydrophobic coatings; cyanoacrylates; promotion of resin-dentin bond longevity in adhesive dentistry; and effects of nanoparticles on nanocomposites Mode I and Mode II fractures.

Applications of Infrared Spectroscopy in Biochemistry, Biology, and Medicine

Applications of Infrared Spectroscopy in Biochemistry, Biology, and Medicine PDF Author: Frank Parker
Publisher: Springer Science & Business Media
ISBN: 1468418726
Category : Science
Languages : en
Pages : 612

Book Description
This book is not intended to be a basic text in infrared spectroscopy. Many such books exist and I have referred to them in the text. Rather, I have tried to find applications that would be interesting to a variety of people: advanced undergraduate chemistry students, graduate students and research workers in several disciplines, spectros copists, and physicians active in research or in the practice of medicine. With this aim in mind there was no intent to have exhaustive coverage of the literature. I should like to acknowledge my use of several books and reviews, which were invaluable in my search for material: G. H. Beaven, E. A. Johnson, H. A. Willis and R. G. 1. Miller, Molecular Spec troscopy, Heywood and Company, Ltd., London, 1961. J. A. Schell man and Charlotte Schellman, 'The Conformation of Polypeptide Chains in Proteins," in The Proteins, Vol. II, 2nd Ed. (H. Neurath, ed.), Academic Press, New York, 1964. R. T. O'Connor, "Application of Infrared Spectrophotometry to Fatty Acid Derivatives," J. Am. Oil Chemists' Soc. 33, 1 (1956). F. L. Kauffman, "Infrared Spectroscopy of Fats and Oils," J. Am. Oil Chemists' Soc. 41,4 (1964). W. J. Potts, Jr., Chemical Infrared Spectroscopy, Vol. I, Techniques, Wiley, New York, 1963. R. S. Tipson, Infrared Spectroscopy of Carbohydrates, National Bureau of Standards Monograph llO, Washington, D.C., 1968. C. N. R. Rao, Chemical Applications of Infrared Spectroscopy, Academic Press, New York, 1963.

Infrared Spectroscopy in Conservation Science

Infrared Spectroscopy in Conservation Science PDF Author: Michele R. Derrick
Publisher: Getty Publications
ISBN: 0892364696
Category : Art
Languages : en
Pages : 252

Book Description
This book provides practical information on the use of infrared (IR) spectroscopy for the analysis of materials found in cultural objects. Designed for scientists and students in the fields of archaeology, art conservation, microscopy, forensics, chemistry, and optics, the book discusses techniques for examining the microscopic amounts of complex, aged components in objects such as paintings, sculptures, and archaeological fragments. Chapters include the history of infrared spectroscopy, the basic parameters of infrared absorption theory, IR instrumentation, analysis methods, sample collection and preparation, and spectra interpretation. The authors cite several case studies, such as examinations of Chumash Indian paints and the Dead Sea Scrolls. The Institute’s Tools for Conservation series provides practical scientific procedures and methodologies for the practice of conservation. The series is specifically directed to conservation scientists, conservators, and technical experts in related fields.

Learning Directory

Learning Directory PDF Author:
Publisher:
ISBN:
Category : Teaching
Languages : en
Pages : 1132

Book Description


Advances in Optics, Vol. 3

Advances in Optics, Vol. 3 PDF Author: Sergey Yurish
Publisher: Lulu.com
ISBN: 8469794396
Category : Technology & Engineering
Languages : en
Pages : 521

Book Description
'Advances in Optics: Reviews' Book Series is a comprehensive study of the field of optics, which provides readers with the most up-to-date coverage of optics, photonics and lasers with a good balance of practical and theoretical aspects. Directed towards both physicists and engineers this Book Series is also suitable for audiences focusing on applications of optics. The Vol.3 is devoted to various topics of applied optics and contains 17 chapters written by 49 experts in the field from 14 countries: Australia, China, India, Israel, Italy, Japan, Malaysia, Mexico, The Netherlands, Poland, Taiwan, UK, USA, Vietnam A clear comprehensive presentation makes these books work well as both a teaching resources and a reference books. The book is intended for researchers and scientists in physics and optics, in academia and industry, as well as postgraduate students.

Advances in Theoretically Interesting Molecules Volume 3

Advances in Theoretically Interesting Molecules Volume 3 PDF Author: Randolph P. Thummel
Publisher: Newnes
ISBN: 1559386983
Category : Science
Languages : en
Pages : 330

Book Description