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Author: United States. Public Health Service. Office of the Surgeon General Publisher: ISBN: Category : Government publications Languages : en Pages : 728
Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Author: United States. Public Health Service. Office of the Surgeon General Publisher: ISBN: Category : Government publications Languages : en Pages : 728
Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Author: Anne Le Publisher: Springer ISBN: 331977736X Category : Medical Languages : en Pages : 186
Book Description
Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
Author: Suzanne H. Reuben Publisher: DIANE Publishing ISBN: 1437934218 Category : Health & Fitness Languages : en Pages : 240
Book Description
Though overall cancer incidence and mortality have continued to decline in recent years, cancer continues to devastate the lives of far too many Americans. In 2009 alone, 1.5 million American men, women, and children were diagnosed with cancer, and 562,000 died from the disease. There is a growing body of evidence linking environmental exposures to cancer. The Pres. Cancer Panel dedicated its 2008¿2009 activities to examining the impact of environmental factors on cancer risk. The Panel considered industrial, occupational, and agricultural exposures as well as exposures related to medical practice, military activities, modern lifestyles, and natural sources. This report presents the Panel¿s recommend. to mitigate or eliminate these barriers. Illus.
Author: National Academies of Sciences, Engineering, and Medicine Publisher: National Academies Press ISBN: 0309679060 Category : Medical Languages : en Pages : 83
Book Description
The National Academies of Sciences, Engineering, and Medicine held the workshop Applying Big Data to Address the Social Determinants of Health in Oncology on October 28â€"29, 2019, in Washington, DC. This workshop examined social determinants of health (SDOH) in the context of cancer, and considered opportunities to effectively leverage big data to improve health equity and reduce disparities. The workshop featured presentations and discussion by experts in technology, oncology, and SDOH, as well as representatives from government, industry, academia, and health care systems. This publication summarizes the presentations and discussions from the workshop.
Author: Joseph A. Gallian Publisher: ISBN: 9780821843215 Category : Mathematics Languages : en Pages : 455
Book Description
Descriptions of summer research programs: The AIM REU: Individual projects with a common theme by D. W. Farmer The Applied Mathematical Sciences Summer Institute by E. T. Camacho and S. A. Wirkus Promoting research and minority participantion via undergraduate research in the mathematical sciences. MTBI/SUMS-Arizona State University by C. Castillo-Chavez, C. Castillo-Garsow, G. Chowell, D. Murillo, and M. Pshaenich Summer mathematics research experience for undergraduates (REU) at Brigham Young University by M. Dorff Introducing undergraduates for underrepresented minorities to mathematical research: The CSU Channel Islands/California Lutheran University REU, 2004-2006 by C. Wyels The REUT and NREUP programs at California State University, Chico by C. M. Gallagher and T. W. Mattman Undergraduate research at Canisius. Geometry and physics on graphs, summer 2006 by S. Prassidis The NSF REU at Central Michigan University by S. Narayan and K. Smith Claremont Colleges REU, 2005-07 by J. Hoste The first summer undergraduate research program at Clayton State University by A. Lanz Clemson REU in computational number theory and combinatorics by N. Calkin and K. James Research with pre-mathematicians by C. R. Johnson Traditional roots, new beginnings: Transitions in undergraduate research in mathematics at ETSU by A. P. Godbole Undergraduate research in mathematics at Grand Valley State University by S. Schlicker The Hope College REU program by T. Pennings The REU experience at Iowa State University by L. Hogben Lafayette College's REU by G. Gordon LSU REU: Graphs, knots, & Dessins in topology, number theory & geometry by N. W. Stoltzfus, R. V. Perlis, and J. W. Hoffman Mount Holyoke College mathematics summer research institute by M. M. Robinson The director's summer program at the NSA by T. White REU in mathematical biology at Penn State Erie, The Behrend College by J. P. Previte, M. A. Rutter, and S. A. Stevens The Rice University Summer Institute of Statistics (RUSIS) by J. Rojo The Rose-Hulman REU in mathematics by K. Bryan The REU program at DIMACS/Rutgers University by B. J. Latka and F. S. Roberts The SUNY Potsdam-Clarkson University REU program by J. Foisy The Trinity University research experiences for undergraduates in mathematics program by S. Chapman Undergraduate research in mathematics at the University of Akron by J. D. Adler The Duluth undergraduate research program 1977-2006 by J. A. Gallian Promoting undergraduate research in mathematics at the University of Nebraska-Lincoln by J. L. Walker, W. Ledder, R. Rebarber, and G. Woodward REU site: Algorithmic combinatorics on words by F. Blanchet-Sadri Promoting undergraduate research by T. Aktosun Research experiences for undergraduates inverse problems for electrical networks by J. A. Morrow Valparaiso experiences in research for undergraduates in mathematics by R. Gillman and Z. Szaniszlo Wabash Summer Institute in Algebra (WSIA) by M. Axtell, J. D. Phillips, and W. Turner THe SMALL program at Williams College by C. E. Silva and F. Morgan Industrial mathematics and statistics research for undergraduates at WPI by A. C. Heinricher and S. L. Weekes Descriptions of summer enrichment programs: Twelve years of summer program for women in mathematics-What works and why? by M. M. Gupta Research experience for undergraduates in numerical analysis and scientific computing: An international program by G. Fairweather and B. M. Moskal Articles: The Long-Term Undergraduate Research (LURE) model by S. S. Adams, J. A. Davis, N. Eugene, K. Hoke, S. Narayan, and K. Smith Research with students from underrepresented groups by R. Ashley, A. Ayela-Uwangue, F. Cabrera, C. Callesano, and D. A. Narayan Research classes at Gettysburg College by B. Bajnok Research in industrial projects for students: A unique undergraduate experience by S. Beggs What students say about their REU experience by F. Connolly and J. A. Gallian Diversity issues in undergraduate research by R. Cortez, D. Davenport, H
Author: Álvaro Rocha Publisher: Springer ISBN: 3319734504 Category : Technology & Engineering Languages : en Pages : 1170
Book Description
This book includes a selection of articles from the 2018 International Conference on Information Technology & Systems (ICITS 18), held on January 10 – 12, 2018, at the Universidad Estatal Península de Santa Elena, Libertad City, Ecuador. ICIST is a global forum for researchers and practitioners to present and discuss recent findings and innovations, current trends, lessons learned and the challenges of modern information technology and systems research, together with their technological development and applications. The main topics covered include information and knowledge management; organizational models and information systems; software and systems modeling; software systems, architectures, applications and tools; multimedia systems and applications; computer networks, mobility and pervasive systems; intelligent and decision support systems; big data analytics and applications; human–computer interaction; ethics, computers & security; health informatics; and information technologies in education.
Author: Charles Swanton Publisher: Perspectives Cshl ISBN: 9781621821434 Category : Medical Languages : en Pages : 350
Book Description
Tumor progression is driven by mutations that confer growth advantages to different subpopulations of cancer cells. As a tumor grows, these subpopulations expand, accumulate new mutations, and are subjected to selective pressures from the environment, including anticancer interventions. This process, termed clonal evolution, can lead to the emergence of therapy-resistant tumors and poses a major challenge for cancer eradication efforts. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines cancer progression as an evolutionary process and explores how this way of looking at cancer may lead to more effective strategies for managing and treating it. The contributors review efforts to characterize the subclonal architecture and dynamics of tumors, understand the roles of chromosomal instability, driver mutations, and mutation order, and determine how cancer cells respond to selective pressures imposed by anticancer agents, immune cells, and other components of the tumor microenvironment. They compare cancer evolution to organismal evolution and describe how ecological theories and mathematical models are being used to understand the complex dynamics between a tumor and its microenvironment during cancer progression. The authors also discuss improved methods to monitor tumor evolution (e.g., liquid biopsies) and the development of more effective strategies for managing and treating cancers (e.g., immunotherapies). This volume will therefore serve as a vital reference for all cancer biologists as well as anyone seeking to improve clinical outcomes for patients with cancer.
Author: United States. Public Health Service. Office of the Surgeon General
Author: United States. Public Health Service. Office of the Surgeon General
Author: Anne Le
Author: 
Author: 
Author: Suzanne H. Reuben
Author: National Academies of Sciences, Engineering, and Medicine
Author: Joseph A. Gallian
Author: American Medical Association
Author: Álvaro Rocha
Author: Charles Swanton