Author: Werner R. Loewenstein Publisher: Springer Science & Business Media ISBN: 3642650635 Category : Science Languages : en Pages : 630
Book Description
Why should there be a handbook of sensory physiology, and if so, why now' The editors have asked this question, marshalled all of the arguments that seemed to speak against their project, and then discovered that most of these arguments really spoke in favor of it: there seemed to be no doubt that the attempt should be made and that it should be made now. No complete overview of sensory physiology has been attempted since Bethe's "Handbuch der normalen und pathologischen Physiologie", nearly forty years ago. Since then, the field has evolved with unforeseen rapidity. Although electric probing of single peripheral nerve fibers was begun by ADRIAN and ZOTTERMAN as early as 1926, in the somatosensory system, and extended to single optic nerve fibers by HARTLINE in 1932, the real upsurge of such single-unit studies has only come during the last two decades. Single-cell electrophysiology has now been applied to all sensory modalities and on almost every conceivable phylogenetic level. It has begun to clarify peripheral receptor action and is adding to our. understanding of the central processing of sensory information. In parallel with these developments, there have been fundamental studies of the physics and chemistry of the receptors themselves: these studies are leading to insights into the mechanisms of energy transduction and nerve impulse initiation.
Author: Krishna C. Persaud Publisher: CRC Press ISBN: 1439871728 Category : Medical Languages : en Pages : 237
Book Description
Many advances have been made in the last decade in the understanding of the computational principles underlying olfactory system functioning. Neuromorphic Olfaction is a collaboration among European researchers who, through NEUROCHEM (Fp7-Grant Agreement Number 216916)-a challenging and innovative European-funded project-introduce novel computing p
Author: John R. Heckenlively Publisher: MIT Press ISBN: 0262083469 Category : Medical Languages : en Pages : 1033
Book Description
The long-awaited second edition of an authoritative reference on electrophysiologic vision testing, including detailed information on techniques and problems, basic physiology and anatomy, theoretical concepts, and clinical findings; with extensive new material. This authoritative text is the only comprehensive reference available on electrophysiologic vision testing, offering both practical information on techniques and problems as well as basic physiology and anatomy, theoretical concepts, and clinical correlations. The second edition, of the widely used text, offers extensive new material and updated information: 65 of the 84 chapters are completely new, with the changes reflecting recent advances in the field. The book will continue to be an essential resource for practitioners and scholars from a range of disciplines within vision science. The contributions not only cover new information—important material that is likely to become more important in the next decade—but also offer a long-range perspective on the field and its remarkable development in the last century. After discussing the history and background of clinical electrophysiology, the book introduces the anatomy of the retina and principles of cell biology in the visual pathways at the molecular, physiological, and biochemical levels. It relates these new findings to the techniques and interpretations of clinical tests, including the electro-oculogram (EOG), electroretinogram (ERG), and visual evoked potentials (VEP), which are discussed in detail, as are equipment, data acquisition and analysis, principles and protocols for clinical testing, diseases and dysfunction, and animal testing. Notable additions for this edition include chapters on the origin of electroretinogram waveforms, multifocal techniques, testing in standard laboratory animals, recent advances in analysis of abnormalities in disease, and the applications of these techniques to the study of genetic abnormalities.
Author: Lisa Bartee Publisher: ISBN: 9781636350417 Category : Languages : en Pages :
Book Description
The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research.
Author: Brian J Arey Publisher: Elsevier ISBN: 0124115071 Category : Science Languages : en Pages : 317
Book Description
Biased Signaling in Physiology, Pharmacology and Therapeutics is a unique and essential reference for the scientific community concerning how conformational-dependent activation is a common phenomenon across many classes of receptors or signaling molecules. It discusses the role of conformational dynamics in leading to signaling bias across different classes of receptors and signaling molecules. By providing a broader view of signaling bias, this resource helps to explain common mechanisms shared across receptor classes and how this can be utilized to elucidate their cellular activity and better understand their therapeutic potential. Written for both new and established scientists in pharmacology, cell biology, biochemistry, and signal transduction, as well as physicians, this book clearly illustrates how biased receptor signaling can be utilized to develop and understand complex pharmacology. Chapters are each focused on a specific class of receptor or other important topic and make use of real-world examples illustrating how the latest research in signal transduction has led to a better understanding of pharmacology and cell biology. This structure creates a basis for understanding that physiological signalling bias has been selected by nature in order to provide complex and tissue- specific biological responses in the face of limited receptors and signaling pathways. This book provides a framework to reveal that these physiological mechanisms are not restricted to one receptor type or family and thus presents receptor signaling from a newer, more global perspective. - Offers a unique and valuable resource on biased receptor signaling that provides a global view for better understanding pharmacology across many receptor families - Integrates biased receptor signaling, physiology, and pharmacology to place this emerging science within the context of treating disease - Includes important chapters on both the pharmaceutical and therapeutic implications of biased signaling
Author: Wolfgang B. Liedtke, MD, PH.D. Publisher: CRC Press ISBN: 1420005847 Category : Medical Languages : en Pages : 502
Book Description
Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st
Author: Robert F. Schmidt Publisher: Springer Science & Business Media ISBN: 3642825982 Category : Medical Languages : en Pages : 310
Book Description
Since 1978 this textbook, to the gratification of its authors and publisher, has found an undiminished readership. Recent research in sensory physiology has progressed so rapidly that this third edition, like the second, has required thorough revision. The understanding of pain, in particular, has increased to a remarkable degree. This development is reflected here in the appearance, for the first time, of a chapter devoted entirely to the subject "Nociception and Pain". In view of the great clinical significance of pain, it seemed necessary to broaden the scope of the discussion, so that in addition to the aspects directly related to sensory physiology consideration is given to the pathophysiology, pharmacology and psychology of pain. The chapters present in earlier editions have also been carefully reexamined and, where necessary, revised and extended. Most of the illustrations provided for the first edition by the Stuttgart studio Gay & Benz have been retained. Some required alteration or replacement, and a number of new illustrations have been added. For the meticulous skill with which she transformed our ideas into graphs and drawings, we are most grateful to Mrs. Regine Gattung-Petith.
Author: Werner R. Loewenstein
Author: 
Author: Krishna C. Persaud
Author: John R. Heckenlively
Author: Lisa Bartee
Author: Matthew E. Cross
Author: Brian J Arey
Author: R. J. Lefkowitz
Author: Wolfgang B. Liedtke, MD, PH.D.
Author: Robert F. Schmidt