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Prevention Measures for Cirrhosis of Liver and Its Progression

Prevention Measures for Cirrhosis of Liver and Its Progression PDF Author: Sharad C Shah
Publisher: JP Medical Ltd
ISBN: 9352501896
Category : Medical
Languages : en
Pages : 169

Book Description
This book is a concise guide to the prevention and management of cirrhosis of the liver. Divided into four sections, the book begins with an overview of the condition, followed by detailed discussion on the different levels of prevention, both major and minor. The third section examines aetiologies and their prevention and the final chapter covers fibrosis (scarring) reversal. This practical guide provides clinicians and trainees with evidence-based direction on the diagnosis, treatment and management of cirrhosis and its many complications. Key Points Concise guide to prevention and management of liver cirrhosis Provides detail on different levels of prevention Covers fibrosis (scarring) reversal Offers evidence-based direction on diagnosis, treatment and management of cirrhosis and its complications

Prevention Measures for Cirrhosis of Liver and Its Progression

Prevention Measures for Cirrhosis of Liver and Its Progression PDF Author: Sharad C Shah
Publisher: JP Medical Ltd
ISBN: 9352501896
Category : Medical
Languages : en
Pages : 169

Book Description
This book is a concise guide to the prevention and management of cirrhosis of the liver. Divided into four sections, the book begins with an overview of the condition, followed by detailed discussion on the different levels of prevention, both major and minor. The third section examines aetiologies and their prevention and the final chapter covers fibrosis (scarring) reversal. This practical guide provides clinicians and trainees with evidence-based direction on the diagnosis, treatment and management of cirrhosis and its many complications. Key Points Concise guide to prevention and management of liver cirrhosis Provides detail on different levels of prevention Covers fibrosis (scarring) reversal Offers evidence-based direction on diagnosis, treatment and management of cirrhosis and its complications

Prevention of Progression in Chronic Liver Disease

Prevention of Progression in Chronic Liver Disease PDF Author: N. Hiyashi
Publisher: Springer Science & Business Media
ISBN: 9780792387961
Category : Medical
Languages : en
Pages : 140

Book Description
In several liver diseases, the underlying cause cannot always be eliminated, i.e. the progression of liver disease cannot be prevented. This is particularly true for non-responders to the treatment of chronic hepatitis C (HCV). It is relevant for more than 40% of patients with HCV genotype 1 and up to 20% of patients with genotype 2 or 3. Several approaches are now underway to prevent or ameliorate mechanisms of disease progression. In Asia, and particularly in Japan, Glycyrrhizine-SNMC has been widely used for this purpose. At present, SNMC is under clinical evaluation in Europe. This book, the proceedings of the Falk Workshop on 'Prevention of Progression in Chronic Liver Disease - An Update on SNMC (Stronger Neo-Minophagen C)' (Part IV of the XII Falk Liver Week, in honour of Hans Popper's 100th birthday) held in Freiburg, Germany, on 22 October 2003, is devoted to the understanding of basic mechanisms of fibrogenesis, the state of the art of non-invasive markers of disease progression that may substitute liver biopsy in the future, and of other predictive parameters indicating disease progression, in particular the development of hepatocellular carcinoma. All these problems are particularly relevant for chronic hepatitis C. A better characterization of so-called non-responders for the treatments available is crucial for the development of new strategies preventing or postponing disease progression. Such strategies should influence fibrogenesis and, thus, cirrhosis formation as well as the development of life threatening complications of liver cirrhosis, including hepatocellular carcinoma. In this volume, the available information on SNMC as an approach to prevent progression of chronic liver disease is discussed by several internationally renowned authors who report on the mechanisms of liver fibrogenesis and fibrolysis, on non-invasive markers of disease progression, and on hepatocellular carcinoma as one of the major complications of liver cirrhosis nowadays. Finally, experts from Japan report on their knowledge and experience concerning the drug SNMC/Glycyrrhizine in the prevention of cirrhosis and HCC, and first study results from Europe are presented.

Chronic Liver Failure

Chronic Liver Failure PDF Author: Pere Ginès
Publisher: Springer Science & Business Media
ISBN: 1607618664
Category : Medical
Languages : en
Pages : 583

Book Description
Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but also to internists, nephrologists, intensive care physicians, and transplant surgeons.

Hepatic Remodeling, Serum Biomarkers and Prevention of Fibrosis Progression in Liver Disease

Hepatic Remodeling, Serum Biomarkers and Prevention of Fibrosis Progression in Liver Disease PDF Author: Vedrana Reichenbach Marinkovic
Publisher:
ISBN:
Category :
Languages : en
Pages :

Book Description


The Evolving Landscape of Liver Cirrhosis Management

The Evolving Landscape of Liver Cirrhosis Management PDF Author: Hitoshi Yoshiji
Publisher: Springer Nature
ISBN: 9811379793
Category : Medical
Languages : en
Pages : 220

Book Description
This book comprehensively covers the latest developments in the diagnosis and treatment of liver cirrhosis, including molecular mechanisms and therapeutic strategies. It elaborates on and explores the relation between chronic liver disease (CLD) and its causes, including viral hepatitis, steatohepatitis, autoimmune liver diseases and/or inherited liver diseases, and sustained liver injury. Furthermore, it discusses various complications such as hepatic encephalopathy, ascites, sarcopenia, esophagogastric varices, muscle cramps and pruritus, and the fact that it frequently leads to the development of hepatocellular carcinoma. CLD is becoming a growing issue with substantial effects on public health, and Evolving Landscape in Management of Liver Cirrhosis provides scholars in gastroenterology and hepatology with invaluable insights. At the same time, it is a valuable resource for clinicians specializing in gastroenterology and hepatology as well as for researchers who are curious about new research on liver disease.

Disease Progression and Disease Prevention in Hepatology and Gastroenterology

Disease Progression and Disease Prevention in Hepatology and Gastroenterology PDF Author: P.R. Galle
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 296

Book Description
Here are the proceedings of the Falk Symposium 150, "Disease Progression and Disease Prevention in the Gastrointestinal Tract", held in Berlin, Germany, October, 2005. Pathogenic processes are described as well as primary and secondary prevention and treatment of disease. The symposium generated new perspectives on the various different pathogenic mechanisms in gastrointestinal organs. The book summarizes the state of the art in these different disease entities, as presented at the meeting.

Liver Cirrhosis and Its Development

Liver Cirrhosis and Its Development PDF Author: J.L. Boyer
Publisher: Springer Science & Business Media
ISBN: 9780792387602
Category : Medical
Languages : en
Pages : 374

Book Description
Liver cirrhosis is a major clinical problem worldwide and is associated with significant morbidity and mortality from its complications, such as liver cell insufficiency with coagulopathy and hepatic encephalopathy, portal hypertension with ascites and gastrointestinal bleeding, hepatorenal syndrome, HCC development and others. This volume, the proceedings of Falk Symposium 115 held in Basel, Switzerland, October 22-24, 1999 (Part II of the Basel Liver Week 1999; XI International Congress of Liver Diseases) covers our present knowledge of the aetiologies and early stages of liver cirrhosis development. Based on this information, strategies are discussed that are aimed at the prevention, early diagnosis and therapy of chronic liver diseases, thus preventing their progression to cirrhosis and its complications, including HCC development. The main topics mentioned above are complemented by three state-of-the-art chapters on modern aspects of medicine in general and hepatology in particular as well as their perspectives beyond the year 2000: `Molecular Medicine', `New Hepatitis Viruses' and `Genetic Liver Diseases: Diagnosis and Therapy'. Introductory chapters focusing on the more basic aspects of the biology of live cells as well as on the mechanisms underlying fibrogenesis, cholestasis and inflammation will be followed by a detailed discussion of the clinically most important causes of liver cirrhosis worldwide: hepatitis viruses B, C and D; toxins (alcohol, drugs and others) as well as metabolic liver diseases (haemochromatosis, Wilson disease, alpha-1-antitrypsin deficiency, porphyria cutanea tarda and protoporphyria). This book, therefore, will interest clinically oriented basic scientists as well as those in clinical practice, givng an update on many aspects of modern hepatology and its perspectives in the next millennium.

Hepatocellular Carcinoma

Hepatocellular Carcinoma PDF Author: Yujin Hoshida
Publisher: Springer
ISBN: 3030215407
Category : Medical
Languages : en
Pages : 366

Book Description
This book provides a comprehensive overview of the current limitations and unmet needs in Hepatocellular Carcinoma (HCC) diagnosis, treatment, and prevention. It also provides newly emerging concepts, approaches, and technologies to address challenges. Topics covered include changing landscape of HCC etiologies in association with health disparities, framework of clinical management algorithm, new and experimental modalities of HCC diagnosis and prognostication, multidisciplinary treatment options including rapidly evolving molecular targeted therapies and immune therapies, multi-omics molecular characterization, and clinically relevant experimental models. The book is intended to assist collaboration between the diverse disciplines and facilitate forward and reverse translation between basic and clinical research by providing a comprehensive overview of relevant areas, covering epidemiological trend and population-level patient management strategies, new diagnostic and prognostic tools, recent advances in the standard care and novel therapeutic approaches, and new concepts in pathogenesis and experimental approaches and tools, by experts and opinion leaders in their respective fields. By thoroughly and concisely covering whole aspects of HCC care, Hepatocellular Carcinoma serves as a valuable reference for multidisciplinary readers, and promotes the development of personalized precision care strategies that lead to substantial improvement of disease burden and patient prognosis in HCC.

Eliminating the Public Health Problem of Hepatitis B and C in the United States

Eliminating the Public Health Problem of Hepatitis B and C in the United States PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309438020
Category : Medical
Languages : en
Pages : 187

Book Description
Hepatitis B and C cause most cases of hepatitis in the United States and the world. The two diseases account for about a million deaths a year and 78 percent of world's hepatocellular carcinoma and more than half of all fatal cirrhosis. In 2013 viral hepatitis, of which hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most common types, surpassed HIV and AIDS to become the seventh leading cause of death worldwide. The world now has the tools to prevent hepatitis B and cure hepatitis C. Perfect vaccination could eradicate HBV, but it would take two generations at least. In the meantime, there is no cure for the millions of people already infected. Conversely, there is no vaccine for HCV, but new direct-acting antivirals can cure 95 percent of chronic infections, though these drugs are unlikely to reach all chronically-infected people anytime soon. This report, the first of two, examines the feasibility of hepatitis B and C elimination in the United States and identifies critical success factors. The phase two report will outline a strategy for meeting the elimination goals discussed in this report.

Handbook of Liver Disease

Handbook of Liver Disease PDF Author: Lawrence Samuel Friedman
Publisher:
ISBN: 9780443066337
Category : Medical
Languages : en
Pages : 481

Book Description
Here's instant access to the symptoms, signs, differential diagnosis, and treatment for the full range of liver disorders. Written by an international 'who's who' of hepatology-and now in full color-this new 2nd Edition provides readers with top-notch, authoritative guidance they can count on! Discusses the hottest topics in the field, such as non-alcoholic steatohepatitis (NASH) and the latest information on liver transplantation. Includes expanded coverage of chronic hepatitis C, most notably the use of combination therapy with peginterferon and ribavirin and improvements in the management of the side effects of antiviral therapy. Offers the most recent therapeutic options for the management of chronic hepatitis B and advances in the understanding of the molecular biology of this virus. Updates the approach to the diagnosis of many liver diseases due to newer tests based on molecular techniques and advances in imaging. Features over 340 full-color illustrations. Uses a redesigned templated, outline format that makes reference a snap. Presents a concise, in-depth clinical summary-in an outline format-of the current practice of hepatology for each major disease entity. Provides a liberal use of tables, algorithms, and figures, rendering complex concepts understandable. Includes key point boxes at the beginning of each chapter, providing at-a-glance access to vital information. Includes alert symbols that highlight information that's critical to patient safety.