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Author: W. Gaebel Publisher: Springer Science & Business Media ISBN: 3709166365 Category : Medical Languages : en Pages : 236
Book Description
Prognosis is a core concept in psychiatry. This book is concerned with prediction of neuroleptic treatment outcome in schizophrenia from a conceptual and methodological point of view. Various aspects of the topic, such as definition and measurement of response, dimensions of treatment outcome, neuropsychological, neuropsychopharmacological and neurobiochemical predictors as well as the clinical application of neuroimaging methods and neurogenetics are treated by experts in the field. One aim of the book is to summarize the present state of the art in prediction research and thereby to provide a useful compendium. Moreover guidelines for future research strategies are formulated.
Author: W. Gaebel Publisher: Springer Science & Business Media ISBN: 3709166365 Category : Medical Languages : en Pages : 236
Book Description
Prognosis is a core concept in psychiatry. This book is concerned with prediction of neuroleptic treatment outcome in schizophrenia from a conceptual and methodological point of view. Various aspects of the topic, such as definition and measurement of response, dimensions of treatment outcome, neuropsychological, neuropsychopharmacological and neurobiochemical predictors as well as the clinical application of neuroimaging methods and neurogenetics are treated by experts in the field. One aim of the book is to summarize the present state of the art in prediction research and thereby to provide a useful compendium. Moreover guidelines for future research strategies are formulated.
Author: Leanne M. Williams, Ph.D. Publisher: American Psychiatric Pub ISBN: 1615371583 Category : Medical Languages : en Pages : 302
Book Description
Precision psychiatry, as outlined in this groundbreaking book, presents a new path forward. By integrating findings from basic and clinical neuroscience, clinical practice, and population-level data, the field seeks to develop therapeutic approaches tailored for specific individuals with a specific constellation of health issues, characteristics, strengths, and symptoms.
Author: Tonmoy Sharma Publisher: OUP Oxford ISBN: 9780198510840 Category : Medical Languages : en Pages : 272
Book Description
New developments in the basic and clinical neurosciences have lead to important advances in our understanding of the events that occur between conception and birth that can influence schizophrenia. At the other end of the life span, some of the most exciting developments in years have recently been coming out of post-mortem studies of patients with schizophrenia. This volume is unique in adopting a lifespan approach to understanding schizophrenia. With contributions from leading scientists in this field, and research from the frontiers of schizophrenia research, the book demonstrates the practical applications of this knowledge in developing new and effective treatments. This volume is a major new addition to the psychiatry literature.
Author: Marek Kubicki Publisher: Springer Nature ISBN: 3030352064 Category : Medical Languages : en Pages : 432
Book Description
This comprehensive book explains the importance of imaging techniques in exploring and understanding the role of brain abnormalities in schizophrenia. The findings obtained using individual imaging modalities and their biological interpretation are reviewed in detail, and updates are provided on methodology, testable hypotheses, limitations, and new directions for research. The coverage also includes important recent applications of neuroimaging to schizophrenia, for example in relation to non-pharmacological interventions, brain development, genetics, and prediction of treatment response and outcome. Written by world renowned experts in the field, the book will be invaluable to all who wish to learn about the newest and most important developments in neuroimaging research in schizophrenia, how these developments relate to the last 30 years of research, and how they can be leveraged to bring us closer to a cure for this devastating disorder. Neuroimaging in Schizophrenia will assist clinicians in navigating what is an extremely complex field and will be a source of insight and stimulation for researchers.
Author: Peter F. Buckley Publisher: Springer Science & Business Media ISBN: 3642452574 Category : Medical Languages : en Pages : 231
Book Description
Schizophrenia is often associated with an inadequate response to pharmacological and non-pharmacological treatments. How to treat patients who have an unsatisfactory response to anti-psychotics, including clozapine - which is unequivocally the most powerful antipsychotic medication for this recalcitrant population - remains a clinical conundrum. A range of adjunctive medications have been tried with mixed results; there has also been renewed interest in the role of neuromodulatory strategies, electroconvulsive therapy, and cognitive and vocational approaches. Perhaps a bright spot for the future lies in the evolution of pharmacogenetic approaches for individualized care. In this book, leading experts from Europe, Australia and the Americas provide a timely appraisal of treatments for the most severely ill schizophrenia patients. This clinically focused book is informed by the latest research on the neurobiology and treatment of schizophrenia. It is comprehensive in scope, covering current treatment options, various add-on approaches, and a range of psychosocial treatments. The contributors are respected experts who have combined their clinical experience with cutting-edge research to provide readers with authoritative information on fundamental aspects of clinical care for schizophrenia.
Author: Neal R. Cutler Publisher: John Wiley & Sons ISBN: 9781444318586 Category : Medical Languages : en Pages : 272
Book Description
Covering the latest advances in CNS drug development, this bookwill guide all those involved in pre-clinical to early clinicaltrials. The authors describe how recent innovations can acceleratethe development of novel CNS compounds, improve early detection ofefficacy and toxicity signals, and increase the safety oflater-stage clinical trials. The current crisis in the drug development industry iscritically reviewed, as well as the steps needed to correct theproblems, including new government-backed regulations andindustry-based innovations designed to accelerate CNS drugdevelopment in the future. Animal-based models of major CNS disorders are described indetail, and the ability of the latest in vitro and computer-basedmodels to simulate CNS disease states and predict drug efficacy andside-effects are examined. Particular attention is given tothe growing use of biomarkers and how they can be used effectivelyin early human trials as signals of potential drug efficacy, aswell as the increasingly important role of imaging studies to guidedose selection. Cognitive assessments that can be useful indicatorsof effect in patient populations are also discussed. Written by a team of clinical scientists involved in CNS drugtrials for over 20 years, and based on a wealth of drug developmentand clinical trial experience, Critical Pathways to Success inCNS Drug Developmentis full of practical advice forsuccessfully designing and executing CNS drug trials, avoidingpotential pitfalls, and complying with government regulations
Author: Katherine J. Aitchison Publisher: CRC Press ISBN: 9781853174353 Category : Medical Languages : en Pages : 152
Book Description
The new edition of this popular handbook has been thoroughly updated to include the latest data concerning treatment of first-episode patients. Drawing from their experience, the authors discuss the presentation and assessment of the first psychotic episode and review the appropriate use of antipsychotic agents and psychosocial approaches in effective management.
Author: Christian L. Shriqui Publisher: American Psychiatric Publishing ISBN: Category : Schizophrenia Languages : en Pages : 904
Book Description
Rarely has a book focused in so comprehensive a manner on the treatment of schizophrenia. Contemporary Issues in the Treatment of Schizophrenia covers the spectrum of therapeutic approaches to the disorder -- biological, pharmacological, and psychosocial -- as well as presenting a wealth of new research on the course and outcome of schizophrenia. This volume should be a welcome addition to the libraries of psychiatrists, psychiatric residents, psychologists, and other health professionals working with schizophrenia.
Author: W. Gaebel
Author: W. Gaebel
Author: Leanne M. Williams, Ph.D.
Author: Tonmoy Sharma
Author: Marek Kubicki
Author: Peter F. Buckley
Author: Neal R. Cutler
Author: Herbert Y. Meltzer
Author: 
Author: Katherine J. Aitchison
Author: Christian L. Shriqui