Author: João Carlos Gonçalves dos Reis
Publisher: Springer Nature
ISBN: 3031470583
Category : Business & Economics
Languages : en
Pages : 609
Book Description
This proceedings volume gathers selected, blinded peer-reviewed contributions presented at the XXIX International Joint Conference on Industrial Engineering and Operations Management (IJCIEOM), held in Lisbon, Portugal, from June 28th to 30th, 2023. This volume focuses especially on the applications of Industrial Engineering and Operations Management for research and practice. It includes relevant information for academics since most of the chapters focus on real-world case studies and systematic reviews. It also provides valuable insights for professionals in the industrial sector by presenting solutions to complex industrial challenges. The 2023 iteration of the IJCIEOM conference had the theme "Developing resilience in Industrial Engineering and Operations Management" and aimed to analyze the resilience of supply chains in the post-COVID-19 era. The works published in this volume focus on how Digital Transformation (DX) and Artificial Intelligence (AI) have made the manufacturing and service industry more resistant to VUCA elements (i.e., volatile, uncertain, complex, and ambiguous). Regarding DX and AI, the research specifically focused on supply chain management, project management, and Industry 4.0. Other studies explore how industrial engineering incorporated innovative and technological concepts into service and product operations. Overall, this volume provides a valuable resource for researchers and practitioners alike as it presents numerous relevant contributions in identifying new challenges and opportunities for industrial engineering and operations management. This conference was sponsored by renowned international industry engineering associations, particularly the American Society for Engineering Management (ASEM), the Institute of Industrial & Systems Engineers (IISE), and the Asociación para el Desarrollo de la Ingeniería de Organización (ADINGOR).
Industrial Engineering and Operations Management
Author: João Carlos Gonçalves dos Reis
Publisher: Springer Nature
ISBN: 3031470583
Category : Business & Economics
Languages : en
Pages : 609
Book Description
This proceedings volume gathers selected, blinded peer-reviewed contributions presented at the XXIX International Joint Conference on Industrial Engineering and Operations Management (IJCIEOM), held in Lisbon, Portugal, from June 28th to 30th, 2023. This volume focuses especially on the applications of Industrial Engineering and Operations Management for research and practice. It includes relevant information for academics since most of the chapters focus on real-world case studies and systematic reviews. It also provides valuable insights for professionals in the industrial sector by presenting solutions to complex industrial challenges. The 2023 iteration of the IJCIEOM conference had the theme "Developing resilience in Industrial Engineering and Operations Management" and aimed to analyze the resilience of supply chains in the post-COVID-19 era. The works published in this volume focus on how Digital Transformation (DX) and Artificial Intelligence (AI) have made the manufacturing and service industry more resistant to VUCA elements (i.e., volatile, uncertain, complex, and ambiguous). Regarding DX and AI, the research specifically focused on supply chain management, project management, and Industry 4.0. Other studies explore how industrial engineering incorporated innovative and technological concepts into service and product operations. Overall, this volume provides a valuable resource for researchers and practitioners alike as it presents numerous relevant contributions in identifying new challenges and opportunities for industrial engineering and operations management. This conference was sponsored by renowned international industry engineering associations, particularly the American Society for Engineering Management (ASEM), the Institute of Industrial & Systems Engineers (IISE), and the Asociación para el Desarrollo de la Ingeniería de Organización (ADINGOR).
Publisher: Springer Nature
ISBN: 3031470583
Category : Business & Economics
Languages : en
Pages : 609
Book Description
This proceedings volume gathers selected, blinded peer-reviewed contributions presented at the XXIX International Joint Conference on Industrial Engineering and Operations Management (IJCIEOM), held in Lisbon, Portugal, from June 28th to 30th, 2023. This volume focuses especially on the applications of Industrial Engineering and Operations Management for research and practice. It includes relevant information for academics since most of the chapters focus on real-world case studies and systematic reviews. It also provides valuable insights for professionals in the industrial sector by presenting solutions to complex industrial challenges. The 2023 iteration of the IJCIEOM conference had the theme "Developing resilience in Industrial Engineering and Operations Management" and aimed to analyze the resilience of supply chains in the post-COVID-19 era. The works published in this volume focus on how Digital Transformation (DX) and Artificial Intelligence (AI) have made the manufacturing and service industry more resistant to VUCA elements (i.e., volatile, uncertain, complex, and ambiguous). Regarding DX and AI, the research specifically focused on supply chain management, project management, and Industry 4.0. Other studies explore how industrial engineering incorporated innovative and technological concepts into service and product operations. Overall, this volume provides a valuable resource for researchers and practitioners alike as it presents numerous relevant contributions in identifying new challenges and opportunities for industrial engineering and operations management. This conference was sponsored by renowned international industry engineering associations, particularly the American Society for Engineering Management (ASEM), the Institute of Industrial & Systems Engineers (IISE), and the Asociación para el Desarrollo de la Ingeniería de Organización (ADINGOR).
Handbook of Healthcare Analytics
Author: Tinglong Dai
Publisher: John Wiley & Sons
ISBN: 1119300967
Category : Business & Economics
Languages : en
Pages : 496
Book Description
How can analytics scholars and healthcare professionals access the most exciting and important healthcare topics and tools for the 21st century? Editors Tinglong Dai and Sridhar Tayur, aided by a team of internationally acclaimed experts, have curated this timely volume to help newcomers and seasoned researchers alike to rapidly comprehend a diverse set of thrusts and tools in this rapidly growing cross-disciplinary field. The Handbook covers a wide range of macro-, meso- and micro-level thrusts—such as market design, competing interests, global health, personalized medicine, residential care and concierge medicine, among others—and structures what has been a highly fragmented research area into a coherent scientific discipline. The handbook also provides an easy-to-comprehend introduction to five essential research tools—Markov decision process, game theory and information economics, queueing games, econometric methods, and data science—by illustrating their uses and applicability on examples from diverse healthcare settings, thus connecting tools with thrusts. The primary audience of the Handbook includes analytics scholars interested in healthcare and healthcare practitioners interested in analytics. This Handbook: Instills analytics scholars with a way of thinking that incorporates behavioral, incentive, and policy considerations in various healthcare settings. This change in perspective—a shift in gaze away from narrow, local and one-off operational improvement efforts that do not replicate, scale or remain sustainable—can lead to new knowledge and innovative solutions that healthcare has been seeking so desperately. Facilitates collaboration between healthcare experts and analytics scholar to frame and tackle their pressing concerns through appropriate modern mathematical tools designed for this very purpose. The handbook is designed to be accessible to the independent reader, and it may be used in a variety of settings, from a short lecture series on specific topics to a semester-long course.
Publisher: John Wiley & Sons
ISBN: 1119300967
Category : Business & Economics
Languages : en
Pages : 496
Book Description
How can analytics scholars and healthcare professionals access the most exciting and important healthcare topics and tools for the 21st century? Editors Tinglong Dai and Sridhar Tayur, aided by a team of internationally acclaimed experts, have curated this timely volume to help newcomers and seasoned researchers alike to rapidly comprehend a diverse set of thrusts and tools in this rapidly growing cross-disciplinary field. The Handbook covers a wide range of macro-, meso- and micro-level thrusts—such as market design, competing interests, global health, personalized medicine, residential care and concierge medicine, among others—and structures what has been a highly fragmented research area into a coherent scientific discipline. The handbook also provides an easy-to-comprehend introduction to five essential research tools—Markov decision process, game theory and information economics, queueing games, econometric methods, and data science—by illustrating their uses and applicability on examples from diverse healthcare settings, thus connecting tools with thrusts. The primary audience of the Handbook includes analytics scholars interested in healthcare and healthcare practitioners interested in analytics. This Handbook: Instills analytics scholars with a way of thinking that incorporates behavioral, incentive, and policy considerations in various healthcare settings. This change in perspective—a shift in gaze away from narrow, local and one-off operational improvement efforts that do not replicate, scale or remain sustainable—can lead to new knowledge and innovative solutions that healthcare has been seeking so desperately. Facilitates collaboration between healthcare experts and analytics scholar to frame and tackle their pressing concerns through appropriate modern mathematical tools designed for this very purpose. The handbook is designed to be accessible to the independent reader, and it may be used in a variety of settings, from a short lecture series on specific topics to a semester-long course.
Supply Chain Management in the Drug Industry
Author: Hedley Rees
Publisher: John Wiley & Sons
ISBN: 0470922842
Category : Medical
Languages : en
Pages : 458
Book Description
This book bridges the gap between practitioners of supply-chain management and pharmaceutical industry experts. It aims to help both these groups understand the different worlds they live in and how to jointly contribute to meaningful improvements in supply-chains within the globally important pharmaceutical sector. Scientific and technical staff must work closely with supply-chain practitioners and other relevant parties to help secure responsive, cost effective and risk mitigated supply chains to compete on a world stage. This should not wait until a drug has been registered, but should start as early as possible in the development process and before registration or clinical trials. The author suggests that CMC (chemistry manufacturing controls) drug development must reset the line of sight – from supply of drug to the clinic and gaining a registration, to the building of a patient value stream. Capable processes and suppliers, streamlined logistics, flexible plant and equipment, shorter cycle times, effective flow of information and reduced waste. All these factors can and should be addressed at the CMC development stage.
Publisher: John Wiley & Sons
ISBN: 0470922842
Category : Medical
Languages : en
Pages : 458
Book Description
This book bridges the gap between practitioners of supply-chain management and pharmaceutical industry experts. It aims to help both these groups understand the different worlds they live in and how to jointly contribute to meaningful improvements in supply-chains within the globally important pharmaceutical sector. Scientific and technical staff must work closely with supply-chain practitioners and other relevant parties to help secure responsive, cost effective and risk mitigated supply chains to compete on a world stage. This should not wait until a drug has been registered, but should start as early as possible in the development process and before registration or clinical trials. The author suggests that CMC (chemistry manufacturing controls) drug development must reset the line of sight – from supply of drug to the clinic and gaining a registration, to the building of a patient value stream. Capable processes and suppliers, streamlined logistics, flexible plant and equipment, shorter cycle times, effective flow of information and reduced waste. All these factors can and should be addressed at the CMC development stage.
Continuous Pharmaceutical Processing
Author: Zoltan K Nagy
Publisher: Springer Nature
ISBN: 3030415244
Category : Medical
Languages : en
Pages : 542
Book Description
Continuous pharmaceutical manufacturing is currently receiving much interest from industry and regulatory authorities, with the joint aim of allowing rapid access of novel therapeutics and existing medications to the public, without compromising high quality. Research groups from different academic institutions have significantly contributed to this field with an immense amount of published research addressing a variety of topics related to continuous processing. The book is structured to have individual chapters on the different continuous unit operations involved in drug substance and drug product manufacturing. A wide spectrum of topics are covered, including basic principles of continuous manufacturing, applications of continuous flow chemistry in drug synthesis, continuous crystallization, continuous drying, feeders and blenders, roll compaction and continuous wet granulation.The underlying theme for each of these chapters is to present to the reader the recent advances in modeling, experimental investigations and equipment design as they pertain to each individual unit operation. The book also includes chapters on quality by design (QbD) and process analytical technology (PAT) for continuous processing, process control strategies including new concepts of quality-by-control (QbC), real-time process management and plant optimization, business and supply chain considerations related to continuous manufacturing as well as safety guidelines related to continuous chemistry. A separate chapter is dedicated to discussing regulatory aspects of continuous manufacturing, with description of current regulatory environment quality/GMP aspects, as well as regulatory gaps and challenges. Our aim from publishing this book is to make it a valuable reference for readers interested in this topic, with a desire to gain a fundamental understanding of engineering principles and mechanistic studies utilized in understanding and developing continuous processes. In addition, our advanced readers and practitioners in this field will find that the technical content of Continuous Pharmaceutical Processing is at the forefront of recent technological advances, with coverage of future prospects and challenges for this technology.
Publisher: Springer Nature
ISBN: 3030415244
Category : Medical
Languages : en
Pages : 542
Book Description
Continuous pharmaceutical manufacturing is currently receiving much interest from industry and regulatory authorities, with the joint aim of allowing rapid access of novel therapeutics and existing medications to the public, without compromising high quality. Research groups from different academic institutions have significantly contributed to this field with an immense amount of published research addressing a variety of topics related to continuous processing. The book is structured to have individual chapters on the different continuous unit operations involved in drug substance and drug product manufacturing. A wide spectrum of topics are covered, including basic principles of continuous manufacturing, applications of continuous flow chemistry in drug synthesis, continuous crystallization, continuous drying, feeders and blenders, roll compaction and continuous wet granulation.The underlying theme for each of these chapters is to present to the reader the recent advances in modeling, experimental investigations and equipment design as they pertain to each individual unit operation. The book also includes chapters on quality by design (QbD) and process analytical technology (PAT) for continuous processing, process control strategies including new concepts of quality-by-control (QbC), real-time process management and plant optimization, business and supply chain considerations related to continuous manufacturing as well as safety guidelines related to continuous chemistry. A separate chapter is dedicated to discussing regulatory aspects of continuous manufacturing, with description of current regulatory environment quality/GMP aspects, as well as regulatory gaps and challenges. Our aim from publishing this book is to make it a valuable reference for readers interested in this topic, with a desire to gain a fundamental understanding of engineering principles and mechanistic studies utilized in understanding and developing continuous processes. In addition, our advanced readers and practitioners in this field will find that the technical content of Continuous Pharmaceutical Processing is at the forefront of recent technological advances, with coverage of future prospects and challenges for this technology.
Handbook of Research on Urban and Humanitarian Logistics
Author: Gonzalez-Feliu, Jesus
Publisher: IGI Global
ISBN: 1522581618
Category : Business & Economics
Languages : en
Pages : 526
Book Description
City logistics is one of the most popular fields of transportation sciences, dealing with sustainably supplying cities and at the same time reducing congestion and pollution related to goods transport in urban areas. Recently, humanitarian, emergency, and crises logistics has been a subject of increasing interest, often seen from an international viewpoint. However, some of the recent natural crises have shown the importance of resilience and reliability of the current urban logistics systems. The Handbook of Research on Urban and Humanitarian Logistics is a critical scholarly publication that addresses urban logistics and resilience, sustainable urban logistics, humanitarian logistics in urban areas both for crisis or long-term, and planning for resilient urban development. Featuring a broad range of topics that discuss the new and future trends in urban logistics and resilient cities, this publication is ideal for public planners; urban planners; company managers in logistics and transport; consulting agencies; regional, national, and international institutions and organizations; researchers; academicians; and students.
Publisher: IGI Global
ISBN: 1522581618
Category : Business & Economics
Languages : en
Pages : 526
Book Description
City logistics is one of the most popular fields of transportation sciences, dealing with sustainably supplying cities and at the same time reducing congestion and pollution related to goods transport in urban areas. Recently, humanitarian, emergency, and crises logistics has been a subject of increasing interest, often seen from an international viewpoint. However, some of the recent natural crises have shown the importance of resilience and reliability of the current urban logistics systems. The Handbook of Research on Urban and Humanitarian Logistics is a critical scholarly publication that addresses urban logistics and resilience, sustainable urban logistics, humanitarian logistics in urban areas both for crisis or long-term, and planning for resilient urban development. Featuring a broad range of topics that discuss the new and future trends in urban logistics and resilient cities, this publication is ideal for public planners; urban planners; company managers in logistics and transport; consulting agencies; regional, national, and international institutions and organizations; researchers; academicians; and students.
Supply Chain Management
Author: Nada R. Sanders
Publisher: John Wiley & Sons
ISBN: 1394187653
Category : Business & Economics
Languages : en
Pages : 404
Book Description
Illustrates SCM best practices while helping students understand the complexities of SCM decision making Now in its fourth edition, Supply Chain Management: A Global Perspective integrates the foundational principles and business-oriented functions of supply chain management (SCM) in one comprehensive volume. Providing students with a balanced and integrated perspective with a global focus, this market-leading textbook highlights the holistic and interconnected nature of SCM while addressing supply chain strategy, design, planning, sourcing, logistics, forecasting, demand planning, operations management, and more. A standard text at universities around the world, Supply Chain Management offers cross-functional coverage, a student-friendly pedagogy, and a wealth of real-world examples of SCM in companies of various sizes. Author Nada R Sanders draws upon her extensive experience in academia and industry to provide both the foundational material required to understand the subject matter and practical tips that demonstrate how the latest techniques are being applied. Supply chain management is advancing rapidly and becoming ever more important in the global business climate. Covering both the underlying principles and practical techniques of SCM, Supply Chain Management: A Global Perspective, Fourth Edition, remains an ideal textbook for upper-level undergraduate courses in Operations Management, Supply Chain Management, and Logistics Management programs. New to this Edition: Updated content in each chapter illustrating the latest business practices in the context of SCM Increased focus on new and emerging technologies, including AI, that are changing supply chains New real-world examples of key concepts applied to supply chains of companies of various sizes and sectors New discussion topics reflecting recent international, government, and organizational policy issues relevant to SCM New and updated cases, discussion questions, examples, and classroom exercises Wiley Advantage: Provides consistent and fully integrated coverage of all key areas of SCM concepts, strategic implementations, and operational techniques Examines supply chain management as a boundary-spanning function that is intertwined with other organizational areas Discusses how recent developments in trade, tax, tariffs, data protection, and national security impact the global supply change Contains extensive pedagogical tools and solved problems designed to make difficult concepts accessible Features a wealth of cases and examples of the latest business practices in supply chain management Includes access to a companion website with an extensive test bank, PowerPoint slides, an instructor’s manual, and other teaching resources
Publisher: John Wiley & Sons
ISBN: 1394187653
Category : Business & Economics
Languages : en
Pages : 404
Book Description
Illustrates SCM best practices while helping students understand the complexities of SCM decision making Now in its fourth edition, Supply Chain Management: A Global Perspective integrates the foundational principles and business-oriented functions of supply chain management (SCM) in one comprehensive volume. Providing students with a balanced and integrated perspective with a global focus, this market-leading textbook highlights the holistic and interconnected nature of SCM while addressing supply chain strategy, design, planning, sourcing, logistics, forecasting, demand planning, operations management, and more. A standard text at universities around the world, Supply Chain Management offers cross-functional coverage, a student-friendly pedagogy, and a wealth of real-world examples of SCM in companies of various sizes. Author Nada R Sanders draws upon her extensive experience in academia and industry to provide both the foundational material required to understand the subject matter and practical tips that demonstrate how the latest techniques are being applied. Supply chain management is advancing rapidly and becoming ever more important in the global business climate. Covering both the underlying principles and practical techniques of SCM, Supply Chain Management: A Global Perspective, Fourth Edition, remains an ideal textbook for upper-level undergraduate courses in Operations Management, Supply Chain Management, and Logistics Management programs. New to this Edition: Updated content in each chapter illustrating the latest business practices in the context of SCM Increased focus on new and emerging technologies, including AI, that are changing supply chains New real-world examples of key concepts applied to supply chains of companies of various sizes and sectors New discussion topics reflecting recent international, government, and organizational policy issues relevant to SCM New and updated cases, discussion questions, examples, and classroom exercises Wiley Advantage: Provides consistent and fully integrated coverage of all key areas of SCM concepts, strategic implementations, and operational techniques Examines supply chain management as a boundary-spanning function that is intertwined with other organizational areas Discusses how recent developments in trade, tax, tariffs, data protection, and national security impact the global supply change Contains extensive pedagogical tools and solved problems designed to make difficult concepts accessible Features a wealth of cases and examples of the latest business practices in supply chain management Includes access to a companion website with an extensive test bank, PowerPoint slides, an instructor’s manual, and other teaching resources
Logistics Management and Strategy
Author: Alan Harrison
Publisher: Pearson UK
ISBN: 1292183721
Category : Business logistics
Languages : en
Pages : 607
Book Description
Publisher: Pearson UK
ISBN: 1292183721
Category : Business logistics
Languages : en
Pages : 607
Book Description
Surviving Supply Chain Integration
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309173418
Category : Technology & Engineering
Languages : en
Pages : 162
Book Description
The managed flow of goods and information from raw material to final sale also known as a "supply chain" affects everythingâ€"from the U.S. gross domestic product to where you can buy your jeans. The nature of a company's supply chain has a significant effect on its success or failureâ€"as in the success of Dell Computer's make-to-order system and the failure of General Motor's vertical integration during the 1998 United Auto Workers strike. Supply Chain Integration looks at this crucial component of business at a time when product design, manufacture, and delivery are changing radically and globally. This book explores the benefits of continuously improving the relationship between the firm, its suppliers, and its customers to ensure the highest added value. This book identifies the state-of-the-art developments that contribute to the success of vertical tiers of suppliers and relates these developments to the capabilities that small and medium-sized manufacturers must have to be viable participants in this system. Strategies for attaining these capabilities through manufacturing extension centers and other technical assistance providers at the national, state, and local level are suggested. This book identifies action steps for small and medium-sized manufacturersâ€"the "seed corn" of business start-up and developmentâ€"to improve supply chain management. The book examines supply chain models from consultant firms, universities, manufacturers, and associations. Topics include the roles of suppliers and other supply chain participants, the rise of outsourcing, the importance of information management, the natural tension between buyer and seller, sources of assistance to small and medium-sized firms, and a host of other issues. Supply Chain Integration will be of interest to industry policymakers, economists, researchers, business leaders, and forward-thinking executives.
Publisher: National Academies Press
ISBN: 0309173418
Category : Technology & Engineering
Languages : en
Pages : 162
Book Description
The managed flow of goods and information from raw material to final sale also known as a "supply chain" affects everythingâ€"from the U.S. gross domestic product to where you can buy your jeans. The nature of a company's supply chain has a significant effect on its success or failureâ€"as in the success of Dell Computer's make-to-order system and the failure of General Motor's vertical integration during the 1998 United Auto Workers strike. Supply Chain Integration looks at this crucial component of business at a time when product design, manufacture, and delivery are changing radically and globally. This book explores the benefits of continuously improving the relationship between the firm, its suppliers, and its customers to ensure the highest added value. This book identifies the state-of-the-art developments that contribute to the success of vertical tiers of suppliers and relates these developments to the capabilities that small and medium-sized manufacturers must have to be viable participants in this system. Strategies for attaining these capabilities through manufacturing extension centers and other technical assistance providers at the national, state, and local level are suggested. This book identifies action steps for small and medium-sized manufacturersâ€"the "seed corn" of business start-up and developmentâ€"to improve supply chain management. The book examines supply chain models from consultant firms, universities, manufacturers, and associations. Topics include the roles of suppliers and other supply chain participants, the rise of outsourcing, the importance of information management, the natural tension between buyer and seller, sources of assistance to small and medium-sized firms, and a host of other issues. Supply Chain Integration will be of interest to industry policymakers, economists, researchers, business leaders, and forward-thinking executives.
Supply Chain Management and its Applications in Computer Science
Author: Saoussen Krichen
Publisher: John Wiley & Sons
ISBN: 1848218710
Category : Computers
Languages : en
Pages : 108
Book Description
Supply chain management is a key topic for a large variety of strategic decision problems. It is essential in making efficient decisions related to the management of inventory and the delivery of final products to customers. The focus of this book is the understanding of the supply chain taxonomy, the different levels of decision and the impact of one level on another depending on the modeling of the addressed objectives. The authors explore the potential problems that can be addressed within the supply chain, such as the inventory, the transportation and issues of holding, and find applications in numerous fields of study, from cloud computing and networking through to industrial sciences. The reader can find each issue described and its positioning in the supply chain determined. A computer science framework is also developed to show how the use of electronic platforms can aid in the handling of these potential problems.
Publisher: John Wiley & Sons
ISBN: 1848218710
Category : Computers
Languages : en
Pages : 108
Book Description
Supply chain management is a key topic for a large variety of strategic decision problems. It is essential in making efficient decisions related to the management of inventory and the delivery of final products to customers. The focus of this book is the understanding of the supply chain taxonomy, the different levels of decision and the impact of one level on another depending on the modeling of the addressed objectives. The authors explore the potential problems that can be addressed within the supply chain, such as the inventory, the transportation and issues of holding, and find applications in numerous fields of study, from cloud computing and networking through to industrial sciences. The reader can find each issue described and its positioning in the supply chain determined. A computer science framework is also developed to show how the use of electronic platforms can aid in the handling of these potential problems.
Statistical Issues in Drug Development
Author: Stephen S. Senn
Publisher: John Wiley & Sons
ISBN: 9780470723579
Category : Medical
Languages : en
Pages : 523
Book Description
Drug development is the process of finding and producingtherapeutically useful pharmaceuticals, turning them into safe andeffective medicine, and producing reliable information regardingthe appropriate dosage and dosing intervals. With regulatoryauthorities demanding increasingly higher standards in suchdevelopments, statistics has become an intrinsic and criticalelement in the design and conduct of drug development programmes. Statistical Issues in Drug Development presents anessential and thought provoking guide to the statistical issues andcontroversies involved in drug development. This highly readable second edition has been updated toinclude: Comprehensive coverage of the design and interpretation ofclinical trials. Expanded sections on missing data, equivalence, meta-analysisand dose finding. An examination of both Bayesian and frequentist methods. A new chapter on pharmacogenomics and expanded coverage ofpharmaco-epidemiology and pharmaco-economics. Coverage of the ICH guidelines, in particular ICH E9,Statistical Principles for Clinical Trials. It is hoped that the book will stimulate dialogue betweenstatisticians and life scientists working within the pharmaceuticalindustry. The accessible and wide-ranging coverage make itessential reading for both statisticians and non-statisticiansworking in the pharmaceutical industry, regulatory bodies andmedical research institutes. There is also much to benefitundergraduate and postgraduate students whose courses include amedical statistics component.
Publisher: John Wiley & Sons
ISBN: 9780470723579
Category : Medical
Languages : en
Pages : 523
Book Description
Drug development is the process of finding and producingtherapeutically useful pharmaceuticals, turning them into safe andeffective medicine, and producing reliable information regardingthe appropriate dosage and dosing intervals. With regulatoryauthorities demanding increasingly higher standards in suchdevelopments, statistics has become an intrinsic and criticalelement in the design and conduct of drug development programmes. Statistical Issues in Drug Development presents anessential and thought provoking guide to the statistical issues andcontroversies involved in drug development. This highly readable second edition has been updated toinclude: Comprehensive coverage of the design and interpretation ofclinical trials. Expanded sections on missing data, equivalence, meta-analysisand dose finding. An examination of both Bayesian and frequentist methods. A new chapter on pharmacogenomics and expanded coverage ofpharmaco-epidemiology and pharmaco-economics. Coverage of the ICH guidelines, in particular ICH E9,Statistical Principles for Clinical Trials. It is hoped that the book will stimulate dialogue betweenstatisticians and life scientists working within the pharmaceuticalindustry. The accessible and wide-ranging coverage make itessential reading for both statisticians and non-statisticiansworking in the pharmaceutical industry, regulatory bodies andmedical research institutes. There is also much to benefitundergraduate and postgraduate students whose courses include amedical statistics component.