Polyphenols-based Nanotherapeutics for Cancer Management PDF Download

Author: Shams Tabrez
Publisher: Springer Nature
ISBN: 9811649359
Category : Medical
Languages : en
Pages : 441

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Book Description
This book reviews the applications of polyphenols in cancer treatment. The initial chapter of the book classifies different polyphenols and discusses their biological and chemical properties. The subsequent chapters then explore the diverse role of polyphenols in modulating signal transduction pathways in cancer including, cellular proliferation, differentiation, apoptosis, inflammation, angiogenesis, and metastasis. This book highlights the usefulness of polyphenol enriched seafood in modulating the anti-tumor and anti-inflammatory cytokine IFN-γ. The book also presents nanoformulation of polyphenol as a promising strategy for their enhanced bioavailability and targeted delivery. Lastly, the book examines the toxicity and safety evaluations of polyphenols as anticancer agents.

Author: Shams Tabrez
Publisher:
ISBN: 9789811649363
Category :
Languages : en
Pages : 0

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Book Description

Author: Anupam Das Talukdar
Publisher: Elsevier
ISBN: 0323904149
Category : Technology & Engineering
Languages : en
Pages : 672

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Book Description
Advances in Nanotechnology-Based Drug Delivery Systems covers the core concepts and latest research regarding the use of nanoscale materials for the development and application of drug delivery systems. The book introduces the reader to nanotechnology in drug delivery, covering the synthesis, encapsulation techniques, characterization and key properties of nanoscale drug delivery systems. Later chapters review the broad range of target applications, including site-specific delivery of drugs for cardiovascular disease, cancer, bacterial infection, bone regeneration. and much more. This book helps translate advanced research into a clinical setting, analyzing the toxicity and health and safety challenges associated with utilizing nanotechnology in biomedicine. This will be a useful reference for those interested in nano-sized drug delivery in biomedicine, including academics and researchers in materials science, biomedical engineering, pharmaceutical science and related disciplines. - Provides a clear introduction to nanotechnology in drug delivery, covering key principles, synthesis, characterization and unique properties of nanoscale materials for drug delivery systems - Discusses preclinical, clinical and patented nano-drug delivery systems, enabling the reader to grasp the current state-of-the-art and market - Covers a broad range of targets for nanoscale drug delivery systems, such as in neurological disorders, oral disease, renal disease, cancer, skin protection, and much more

Author: Chandrabhan Verma
Publisher: John Wiley & Sons
ISBN: 1394203926
Category : Science
Languages : en
Pages : 628

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Book Description
SCIENCE AND ENGINEERING OF POLYPHENOLS A groundbreaking synthesis of rich and varied polyphenol research Polyphenols are a class of compounds, found naturally in fruits and vegetables, whose flexibility and ubiquity give them a vast range of applications in pharmaceutical, environmental, and biological research and development. They play a role in diagnosing and preventing diseases from diabetes to Parkinson’s to Alzheimer’s and have been integral in food preservation. The field of polyphenols research has the potential to touch virtually every area of organic production. Science and Engineering of Polyphenols provides a current and comprehensive overview of this field of research and its latest developments. Long overdue as a ‘state of the field’ synthesis for an area of study that has seen rapid development in recent years, this book promises to be a milestone. Science and Engineering of Polyphenols readers will also find: Treatment of both natural and synthetic polyphenols Detailed discussion of topics including synthesis and characterization of polyphenols, electronic and molecular structure of polyphenols, and many more Supplementary material including websites of interest and updates on the latest research and development Science and Engineering of Polyphenols is ideal for scholars, industrialists, and policymakers in any of the myriad areas of academia and industry touched by polyphenol research.

Author: Heba Abd El-Sattar El-Nashar
Publisher: Bentham Science Publishers
ISBN: 9815179675
Category : Medical
Languages : en
Pages : 232

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Book Description
Natural Products for Skin Diseases: A Treasure Trove for Dermatologic Therapy is an enlightening journey through the realm of natural remedies for various skin diseases. The editors have compiled information on effective and holistic treatment approaches that can be applied in clinical settings. This book brings diverse range of topics, including skin protection against harmful radiation, natural remedies for burns and wounds, management of skin pigmentation issues, and herbal treatments for scabies. It also explores the potential of natural cosmetics and their future applications, along with the use of natural products and nanoparticles in skin delivery. All chapters are contributed by experts in dermatology and herbal medicine, and are supplemented with scientific references for advanced readers. The book primarily serves as a textbook for students in medicine and dermatologists in training. It also serves as a valuable guide for dermatologists, researchers, and healthcare professionals, revealing the treasure trove of benefits that natural products offer for treating skin diseases.

Author: Shakeel Ahmed
Publisher: John Wiley & Sons
ISBN: 1119905036
Category : Technology & Engineering
Languages : en
Pages : 421

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Book Description
NANOTECHNOLOGY IN FUNCTIONAL FOODS The broad applicability of bioactive delivery systems for improving food quality, safety, and human health will make this book a valuable resource for a wide range of readers in industry, research, and academia. Functional foods is an emerging trend in the food industry, whose potential value is determined by whether they are safe with respect to consumer health. Nanotechnology in Functional Foods was written to help the reader better understand the benefits and concerns associated with these foods. In addition to giving an overview of the current state-of-the-art in functional foods, different aspects of the advanced research being conducted on their extraction, synthesis, analysis, and biological effects are presented. Besides focusing on several synthesis techniques, the book also discusses the application of nanoparticles in nutrient delivery and pharmaceuticals, such as nano-emulsions, solid lipid nanoparticles, and polymeric nanoparticles; their properties and interactions with other food components and their impact on the human body; the consumer acceptance and diversification of these nutrients. Moreover, new trends are discussed concerning the application of artificial intelligence in screening various components of functional foods. Audience The book will be central to food scientists, materials scientists, biotechnologists, medicinal chemists, pharmacists, and medical professionals. Tanima Bhattacharya, PhD, is a formulation scientist, who completed her Doctoral degree in Food Processing & Nutrition Science from the Indian Institute of Engineering Science and Technology, Shibpur, West Bengal, India and gained overseas post-doctoral experience from the College of Chemistry and Chemical Engineering Hubei University of China. She has published several scientific research articles in international peer-reviewed journals, and her research interests include the fabrication of biocompatible nanostructures and studying their properties and applications in the area of food science, technology, and biomedical sciences. Shakeel Ahmed, PhD, is an assistant professor of Chemistry at the Higher Education Department, Government of Jammu and Kashmir, India. His PhD degree in Chemistry is from Jamia Millia Islamia, A Central University, New Delhi. He has published several research publications in the area of green nanomaterials and biopolymers for various applications including biomedical, packaging, and water treatment. He has published more than 20 books in the area of nanomaterials and green materials.

Author: Sneh Punia Bangar
Publisher: Royal Society of Chemistry
ISBN: 1837670307
Category : Technology & Engineering
Languages : en
Pages : 428

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Book Description
In recent years, consumers have been concentrating on the health benefits and nutrition from food to preserve a healthy lifestyle. They are looking for colorants derived from natural sources to enhance the nutritional and antioxidant value of foods. Coloured cereals (wheat, rice, barley, oat, maize, sorghum, and millets) contain many phytochemicals, including anthocyanins and carotenoids associated with numerous health benefits. This book presents a comprehensive overview of the bioactive potential, food applications, and health benefits of coloured cereal grains. Novel approaches to the integration of coloured grain into food in the food processing industries are included, reviewing high-value pigments in the bran layer which can easily be extracted and utilized as functional foods and natural colorants. Aimed at researchers carrying out innovative studies, food regulatory and safety authorities and food processing industries who are trying to minimize synthetic food colorants and dyes, this book provides a novel approach to the use of substitute synthetic dyes which can improve the nutritional value, appearance, texture, flavour, and storage properties of food products.

Author: Marcos Roberto de Oliveira
Publisher: Academic Press
ISBN: 0323886183
Category : Science
Languages : en
Pages : 602

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Book Description
Mitochondrial Dysfunction and Nanotherapeutics: Aging, Diseases, and Nanotechnology-Related Strategies in Mitochondrial Medicine provides a comprehensive overview of mitochondrial dysfunction and current strategies for targeting the organelle. Based on the most current research, the editor lined up a team of worldwide experts to cover the most exciting research in the area, considering the impact through the human life span. This book is structured in two parts that provide a good balance of foundational and applied content. Part I deals with an overview of mitochondrial dysfunction and its role in the aging process, including metabolic diseases, neuro-affective and neurodegenerative disorders, sepsis, and toxicological aspects. Part II covers therapeutic substance delivery to mitochondria with a focus on cancer, neurodegenerative diseases, and increasing the bioavailability of natural compounds of interest. Several nanoscale strategies are described. Mitochondrial Dysfunction and Nanotherapeutics: Aging, Diseases, and Nanotechnology-Related Strategies in Mitochondrial Medicine is a complete resource for researchers in this exciting field. Its comprehensive coverage makes this book particularly interesting to bioscience researchers looking to understand the foundations of mitochondrial health throughout the human life span. Additionally, clinician researchers, medical doctors, nutritionists, pharmacologists, and sports scientists may be attracted to the detailed information on the organelle-targeted delivery strategies. - Contains detailed information on mitochondrial dysfunction - Reviews our current understanding of the role of mitochondria in aging - Includes coverage of specific conditions, including sports and affective disorders, among others - Discusses mitochondria targeted delivery of therapeutic compounds

Author: Fazlul H. Sarkar
Publisher: Springer Science & Business Media
ISBN: 9400726309
Category : Medical
Languages : en
Pages : 383

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Book Description
This book is about Nutraceuticals in cancer therapy, specifically targeted and Adjuvant therapy. It shows several approaches for possibly reducing systemic toxicity. This book illustrates the role of several dietary agents, collectively called nutraceuticals or natural agents in the prevention and/or treatment of human malignancies known to be mediated through alterations in multiple molecular targets. This book contains sixteen chapters which begin with historical perspective on the value of natural agents in the prevention of human malignancies followed by a series of current topics on multiple nutraceuticals targeting multiple cancers. This collection would likely be useful for bringing newer generations with broader perspectives in launching cutting-edge innovative molecular research, which would certainly help in designing targeted clinical trials in order to realize the dream of customize strategies for the prevention and/or treatment of human malignancies without causing any systemic toxicity. Moreover, the knowledge gained would allow novel utilization of nutraceuticals as adjunct to both conventional chemotherapy and radiation therapy in order to improve the overall quality of life and survival of patients diagnosed with cancers.

Author: Mithun Rudrapal
Publisher: John Wiley & Sons
ISBN: 1119811775
Category : Medical
Languages : en
Pages : 580

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Book Description
Phytoantioxidants and Nanotherapeutics Discover the medicinal importance of antioxidant herbal medicines, phytochemicals, and nanodelivery systems for a wide range of diseases Phytomedicine has been—and continues to be—central to many cultures and societies due to its low toxicity, low cost, accessibility, and efficacy in treating difficult diseases. In fact, many plant-derived bioactive natural products serve as potential sources of drug leads or therapeutic agents in the treatment of a wide range of human diseases. When combined with nanotechnology, phytomedicine has the potential to affect and impact a tissue-specific site, which can reduce drug dosage and side effects while improving activity. Phytoantioxidants and Nanotherapeutics offers a comprehensive look at the significant role that phytomedicine-derived antioxidants play on the field of medicine, particularly when combined with the nanotechnology-derived drug delivery systems. The book thoroughly covers the herbs, plant extracts, and other dietary elements that may be used as sources of natural antioxidants and similarly highlights the use of phytomedicine- derived bioactive compounds including plant polyphenols and flavonoids to reducing the impact of oxidative stress induced human diseases. The text also demonstrates the biochemical and therapeutic targets of nanodrugs and discusses nanostructure toxicity, while emphasizing the challenges and regulatory issues involved with nanophytotherapeutics. Phytoantioxidants and Nanotherapeutics readers will also find: A helpful bridge between the cutting-edge field of nanotechnology delivery and phytotherapeutics The potential role of bioactive phytochemicals, particularly polyphenolic compounds and flavonoids, in oxidative stress-induced diseases Description of the latest developments on nanotherapeutics of phytoantioxidants for the treatment of certain chronic human diseases, such as cancer, inflammations, diabetes, viral, bacterial and parasitic infections, nervous system disorders, cardiovascular disorders, and neurological diseases. Phytoantioxidants and Nanotherapeutics is a useful reference for drug manufacturers and drug developers, formulation scientists, biomedical scientists, medicinal chemists, phytochemists, healthcare providers, and academics and researchers.