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Author: Tom Nesi Publisher: Macmillan ISBN: 142993185X Category : Business & Economics Languages : en Pages : 317
Book Description
To the millions of Americans who suffer from chronic pain and arthritis, Vioxx seemed like a miracle. One of the most widely promoted and prescribed pain medications in the world -- used by more than twenty million people -- it was endorsed by the medical establishment and celebrities such as Olympic champion figure skater Dorothy Hamill. With annual sales of $2.5 billion, Vioxx became a pharmaceutical bonanza before being abruptly taken off the market in September 2004, after it was revealed that it led to an increased risk of heart-related disease and death. Drawing on internal documents, video footage, court testimony, and exclusive interviews, as well as three decades of experience inside the medical industry, Tom Nesi tells the dramatic story of what the drug's manufacturer, Merck, knew and when. It is a compelling narrative of business and medical science run amok, with a cast of characters ranging from those at the highest levels of the multibillion-dollar pharmaceutical industry to research scientists, marketers, and drug company sales reps. Here also are accounts from physicians, lawyers, financial analysts, and patients and their families whose lives have been forever altered by Vioxx. Set against a fascinating history of the origins of the modern pharmaceutical industry, POISON PILLS is a shocking tale that involves the breakdown of the United States medical system, the failures of the Food and Drug Administration, and enormous profits made by a large pharmaceutical corporation at the potential cost of thousands of lives.
Author: Tom Nesi Publisher: Macmillan ISBN: 142993185X Category : Business & Economics Languages : en Pages : 317
Book Description
To the millions of Americans who suffer from chronic pain and arthritis, Vioxx seemed like a miracle. One of the most widely promoted and prescribed pain medications in the world -- used by more than twenty million people -- it was endorsed by the medical establishment and celebrities such as Olympic champion figure skater Dorothy Hamill. With annual sales of $2.5 billion, Vioxx became a pharmaceutical bonanza before being abruptly taken off the market in September 2004, after it was revealed that it led to an increased risk of heart-related disease and death. Drawing on internal documents, video footage, court testimony, and exclusive interviews, as well as three decades of experience inside the medical industry, Tom Nesi tells the dramatic story of what the drug's manufacturer, Merck, knew and when. It is a compelling narrative of business and medical science run amok, with a cast of characters ranging from those at the highest levels of the multibillion-dollar pharmaceutical industry to research scientists, marketers, and drug company sales reps. Here also are accounts from physicians, lawyers, financial analysts, and patients and their families whose lives have been forever altered by Vioxx. Set against a fascinating history of the origins of the modern pharmaceutical industry, POISON PILLS is a shocking tale that involves the breakdown of the United States medical system, the failures of the Food and Drug Administration, and enormous profits made by a large pharmaceutical corporation at the potential cost of thousands of lives.
Author: Gordon Polk Publisher: ISBN: 9781420888898 Category : Medical Languages : en Pages : 308
Book Description
In 1994, the prospect of finding a cure for AIDS represented a dream that scientists and physicians hoped to realize by the new millennium. Despite advances in medicines and treatments, a single cure still remains elusive to this day. What goes on behind the scenes in the world of new drug development is often secretive and deceptive. This mystery reveals the motives of a pharmaceutical company that is on the cusp of launching a revolutionary treatment for AIDS. Patient access to the new drug KLX is hampered by deception, greed and murder. The societal impact of AIDS is poignantly outlined in this story about innocent humans who are affected by the actions of a few executives controlling a multi-billion dollar pharmaceutical market. From homeless people to politicians and government bureaucrats, conspiracies are created between unlikely allies. Only a young employee of Linfeld Pharmaceuticals has the courage to fight for the hope of thousands suffering from AIDS.
Author: Patrick A. Gaughan Publisher: John Wiley & Sons ISBN: 0470135948 Category : Business & Economics Languages : en Pages : 639
Book Description
Modern restructuring techniques for a global business landscape Corporate restructurings are an indispensable tool in building a new generation of re-engineered companies with the power and resources to compete on a global playing field. Written from a practical and historical perspective, Mergers, Acquisitions, and Corporate Restructurings, Fourth Edition carefully analyzes the strategies and motives that inspire M&As, the laws and rules that govern the field, as well as the offensive and defensive techniques of hostile acquisitions. In this thoroughly revised Fourth Edition, author and business valuation expert Patrick Gaughan provides a fresh perspective on M&As in today's global business landscape, and how your company can reap the benefits from the various forms of restructurings available. Packed with the most up-to-date research, graphs, and case studies, Mergers, Acquisitions, and Corporate Restructurings, Fourth Edition explores: * Recent takeover trends including the role of private equity firms and hedge funds * Most effective offensive and defensive tactics in hostile bids * A review of the effect of shareholder wealth on a variety of takeover actions * Modern, historical, and global perspectives on the field * The various forms of downsizing including divestitures, spinoffs, and equity carve-outs * Bankruptcy as an effective restructuring technique * Latest developments in corporate governance * Pros and cons of joint ventures and strategic alliances * Primary methods used to value public and private companies
Author: M. A. Granovsky Publisher: ISBN: 9780578111384 Category : Law firms Languages : en Pages : 350
Book Description
It's the drug of the century, a miracle weight loss compound worth billions, invented by Jon Vickers shortly before his death. So why is Jon's brother Benedict risking his inheritance, his brother's legacy, and even his own life to keep the drug from the market? And why is Olga Mueller, a jaded lawyer Benedict met by chance while traveling to Istanbul, willing to help? Can they take on a powerful venture capitalist and a ruthless top-tier law firm and win? Or even survive? In a world where money rules, does truth stand a chance?
Author: Donald DePamphilis Publisher: Academic Press ISBN: 0080959091 Category : Business & Economics Languages : en Pages : 290
Book Description
Mergers and Acquisitions Basics: All You Need to Know provides an introduction to the fundamental concepts of mergers and acquisitions. Key concepts discussed include M&As as change agents in the context of corporate restructuring; legal structures and strategies employed in corporate restructuring; takeover strategies and the impact on corporate governance; takeover defenses; and players who make mergers and acquisitions happen. The book also covers developing a business plan and the tools used to evaluate, display, and communicate information to key constituencies both inside and outside the corporation; the acquisition planning process; the negotiation, integration planning, and closing phases; financing transactions; and M&A post-merger integration.This book is written for buyers and sellers of businesses, financial analysts, chief executive officers, chief financial officers, operating managers, investment bankers, and portfolio managers. Others who may have an interest include bank lending officers, venture capitalists, government regulators, human resource managers, entrepreneurs, and board members. The book may also be used as a companion or supplemental text for undergraduate and graduate students taking courses on mergers and acquisitions, corporate restructuring, business strategy, management, governance, and entrepreneurship. - Describes a broad view of the mergers and acquisition process to illustrate agents' interactions - Simplifies without overgeneralizing - Bases conclusions on empirical evidence, not experience and opinion - Features a recent business case at the end of each chapter
Author: Deborah Blum Publisher: Penguin ISBN: 0525560289 Category : Political Science Languages : en Pages : 370
Book Description
A New York Times Notable Book The inspiration for PBS's AMERICAN EXPERIENCE film The Poison Squad. From Pulitzer Prize winner and New York Times-bestselling author Deborah Blum, the dramatic true story of how food was made safe in the United States and the heroes, led by the inimitable Dr. Harvey Washington Wiley, who fought for change By the end of nineteenth century, food was dangerous. Lethal, even. "Milk" might contain formaldehyde, most often used to embalm corpses. Decaying meat was preserved with both salicylic acid, a pharmaceutical chemical, and borax, a compound first identified as a cleaning product. This was not by accident; food manufacturers had rushed to embrace the rise of industrial chemistry, and were knowingly selling harmful products. Unchecked by government regulation, basic safety, or even labelling requirements, they put profit before the health of their customers. By some estimates, in New York City alone, thousands of children were killed by "embalmed milk" every year. Citizens--activists, journalists, scientists, and women's groups--began agitating for change. But even as protective measures were enacted in Europe, American corporations blocked even modest regulations. Then, in 1883, Dr. Harvey Washington Wiley, a chemistry professor from Purdue University, was named chief chemist of the agriculture department, and the agency began methodically investigating food and drink fraud, even conducting shocking human tests on groups of young men who came to be known as, "The Poison Squad." Over the next thirty years, a titanic struggle took place, with the courageous and fascinating Dr. Wiley campaigning indefatigably for food safety and consumer protection. Together with a gallant cast, including the muckraking reporter Upton Sinclair, whose fiction revealed the horrific truth about the Chicago stockyards; Fannie Farmer, then the most famous cookbook author in the country; and Henry J. Heinz, one of the few food producers who actively advocated for pure food, Dr. Wiley changed history. When the landmark 1906 Food and Drug Act was finally passed, it was known across the land, as "Dr. Wiley's Law." Blum brings to life this timeless and hugely satisfying "David and Goliath" tale with righteous verve and style, driving home the moral imperative of confronting corporate greed and government corruption with a bracing clarity, which speaks resoundingly to the enormous social and political challenges we face today.
Author: Nilesh Nilkanth Oak Publisher: Bhima, LLC ISBN: 9780983034414 Category : Languages : en Pages : 226
Book Description
The chronology and astronomy evidence of the Mahabharata text is elegantly analyzed against the background of modern astronomy. The synthesis leads to 5561 BCE as the year of Mahabharata war. The meticulous research of this book decisively falsifies all existing claims for the year of Mahabharata war. A must-read for anyone interested in History of Hindu civilization.
Author: Katherine Eban Publisher: HarperCollins ISBN: 0063054108 Category : Medical Languages : en Pages : 523
Book Description
A NEW YORK TIMES BESTSELLER * New York Times Notable Book * Best Book of the Year: New York Public Library, Kirkus Reviews, Science Friday With a new postscript by the author From an award-winning journalist, an explosive narrative investigation of the generic drug boom that reveals fraud and life-threatening dangers on a global scale—The Jungle for pharmaceuticals Many have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true? Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects. The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.
Author: Tom Nesi
Author: Tom Nesi
Author: Glenn Kaplan
Author: Gordon Polk
Author: Patrick A. Gaughan
Author: Philip Nitschke
Author: M. A. Granovsky
Author: Donald DePamphilis
Author: Deborah Blum
Author: Nilesh Nilkanth Oak
Author: Katherine Eban