Author: E. De Clercq Publisher: Elsevier ISBN: 0080548245 Category : Medical Languages : en Pages : 265
Book Description
Regularly reviewing the "state-of-the-art" developments in the antiviral drug research field, this latest volume spans the conceptual design and chemical synthesis of new antiviral compounds. It discusses their structure-activity relationship, mechanism and targets of action, pharmacological behavior, antiviral activity spectrum, and therapeutic potential for clinical use.
Author: Minoru Fukuda Publisher: ISBN: Category : Science Languages : en Pages : 288
Book Description
Cell-surface carbohydrates play critical roles in cell-cell interactions. This well-written book brings together leading researchers to detail major recent advances regarding our understanding of the molecular mechanisms underlying such processes. Emphasis is given to cell type, specific carbohydrate expression, and the carbohydrates and proteins involved in cell recognition. Topics include the molecular structure of animal lectins, carbohydrate recognition in cell-cell interaction, chemical synthesis of oligosaccharides, conformational studies on oligosaccharides, and cell-surface carbohydrates, among others. Also included is a full discussion of key experimental approaches such as chemical synthesis and the three-dimensional structural analysis of carbohydrates. Providing both an up-to-date description of the subject and a forecast of likely future developments, Molecular Glycobiology is a much-needed synopsis of an exciting and rapidly expanding field. It will be welcomed by students and researchers in molecular biology, biochemistry, cell biology, and glycobiology.
Author: George C. Khachatourians Publisher: CRC Press ISBN: 9780203910979 Category : Science Languages : en Pages : 910
Book Description
With contributions from nearly 130 internationally renowned experts in the field, this reference details advances in transgenic plant construction and explores the social, political, and legal aspects of genetic plant manipulation. It provides analyzes of the history, genetics, physiology, and cultivation of over 30 species of transgenic seeds, fruits, and vegetables. Stressing the impact of genetic engineering strategies on the nutritional and functional benefit of foods as well as on consumer health and the global market economy, the book covers methods of gene marking, transferring, and tagging public perceptions to the selective breeding, hybridization, and recombinant DNA manipulation of food.
Author: Ajit Varki Publisher: Twelve ISBN: 1455511927 Category : Science Languages : en Pages : 290
Book Description
The history of science abounds with momentous theories that disrupted conventional wisdom and yet were eventually proven true. Ajit Varki and Danny Brower's "Mind over Reality" theory is poised to be one such idea-a concept that runs counter to commonly-held notions about human evolution but that may hold the key to understanding why humans evolved as we did, leaving all other related species far behind. At a chance meeting in 2005, Brower, a geneticist, posed an unusual idea to Varki that he believed could explain the origins of human uniqueness among the world's species: Why is there no humanlike elephant or humanlike dolphin, despite millions of years of evolutionary opportunity? Why is it that humans alone can understand the minds of others? Haunted by their encounter, Varki tried years later to contact Brower only to discover that he had died unexpectedly. Inspired by an incomplete manuscript Brower left behind, Denial presents a radical new theory on the origins of our species. It was not, the authors argue, a biological leap that set humanity apart from other species, but a psychological one: namely, the uniquely human ability to deny reality in the face of inarguable evidence-including the willful ignorance of our own inevitable deaths. The awareness of our own mortality could have caused anxieties that resulted in our avoiding the risks of competing to procreate-an evolutionary dead-end. Humans therefore needed to evolve a mechanism for overcoming this hurdle: the denial of reality. As a consequence of this evolutionary quirk we now deny any aspects of reality that are not to our liking-we smoke cigarettes, eat unhealthy foods, and avoid exercise, knowing these habits are a prescription for an early death. And so what has worked to establish our species could be our undoing if we continue to deny the consequences of unrealistic approaches to everything from personal health to financial risk-taking to climate change. On the other hand reality-denial affords us many valuable attributes, such as optimism, confidence, and courage in the face of long odds. Presented in homage to Brower's original thinking, Denial offers a powerful warning about the dangers inherent in our remarkable ability to ignore reality-a gift that will either lead to our downfall, or continue to be our greatest asset.
Author: Elizaveta Padalko Publisher: Leuven University Press ISBN: 9789058674494 Category : Medical Languages : en Pages : 186
Book Description
This is a Ph.D. dissertation. Coxsackieviruses B (CBV) are considered to be the principal etiological agent of viral myocarditis. In analogy to many other viral illnesses, both direct viral injury as well as the immune response plays an important role in the pathogenesis of viral heart disease. At the present moment not a single specific therapeutic agent is available for the treatment of CVB-induced myocarditis. The main goal of this work was to explore new strategies for the treatment of viral myocarditis based on the current scientific knowledge about the pathogenesis of this disease.
Author: Hans-Joachim Gabius Publisher: John Wiley & Sons ISBN: 3527614729 Category : Science Languages : en Pages : 663
Book Description
A comprehensive survey of the topic, ranging from basic molecular research to clinical applications. Critical reviews by leading experts in each field summarize the state of knowledge and discuss the anticipated benefits of novel approaches and strategies. These include the impact of modern analysis techniques on glycobiology, the use of synthetic neoglycoproteins, or the clinical consequences of new insights into the physiological role of lectins and glycoconjugates in pathology, oncology, immunity, neuroscience and reproduction medicine. Throughout, the aim is to separate realistic applications from mere hopes.
Author: Mikael Bols Publisher: Wiley-Interscience ISBN: Category : Science Languages : en Pages : 202
Book Description
Bols delivers an original and effective presentation that unravels secrets from carbohydrate chemistry. He specifically describes which carbohydrates are best used in Synthesis and how to obtain them. The first half of this indispensable reference contains a dictionary-like list of compounds that can be prepared in a few steps from commercially cheap carbohydrates. The latter section describes which carbohydrates are commercially and inexpensively available along with the chemistry that can be used to convert them into useful building blocks.
Author: E. De Clercq
Author: Azita Alavi
Author: Minoru Fukuda
Author: George C. Khachatourians
Author: Mukesh Kumar Mishra (Journalist)
Author: Ajit Varki
Author: Elizaveta Padalko
Author: Hans-Joachim Gabius
Author: Mikael Bols